T80.81 vs T80.810A
T80.81 (Extravasation of vesicant agent) compared with T80.810A (Extravasation of vesicant antineoplastic chemotherapy, initial encounter), from the official CMS tabular data.
Current data releases:ICD-10-CM FY2027 · ICD-10-PCS FY2027 · HCPCS October 2026 · MS-DRG v44 · Medicare Code Editor v44.0 · NCCI PTP Q4 2026 · MUE Q4 2026 · NCD code lists 2026-01 · LCD export September 28, 2026 · All releases and sources
Summary
These codes represent different levels of the same hierarchy: T80.81 is the non-billable header that contains T80.810A, so only T80.810A (or a sibling) is reported.
Registry fact- What is different?
Title wording and billing status.The titles share “Extravasation of vesicant”; T80.81 says “agent” where T80.810A says “antineoplastic chemotherapy, initial encounter”. T80.81 is a non-billable header; T80.810A is billable.
Registry fact
- Can these codes be reported together?
Not as a pair.T80.81 is the non-billable header that contains T80.810A. A header is not reported on a claim, so the choice is T80.810A or a sibling that matches the documentation.
Registry fact
- Is there an Excludes1 relationship?
None.Neither entry carries an Excludes1 note that names the other code.
Official rule
- Is there an Excludes2 relationship?
None.Neither entry carries an Excludes2 note that names the other code. T80.81 carries 28 Excludes2 notes and T80.810A carries 28 Excludes2 notes covering other codes; the side-by-side table quotes them.
Official rule
- Is one more specific?
Yes.T80.810A is a subdivision of T80.81 in the tabular hierarchy, so it is the more specific of the two.
Registry fact
- Is one a parent or header code?
Yes.T80.81 is the non-billable header that contains T80.810A. A header stands for the whole family beneath it and is not reported on a claim.
Registry fact
- Are there sequencing instructions?
None.Neither entry carries a Code First or Use Additional Code note that names the other.
Official rule
- Are there other coding relationships?
None found.No laterality, encounter-phase, Table of Neoplasms, Table of Drugs and Chemicals, or history-versus-active-disease relationship links these codes.
MedCoder-derived
Official rule: a tabular instructional note or a section of the ICD-10-CM Official Guidelines, quoted as published. Registry fact: the codes’ own published attributes (titles, billable status, position in the hierarchy, code set). MedCoder-derived: a reading MedCoder computes from those facts; it is not itself a rule. How to read the labels
Can these codes be reported together?
Not as a pair — T80.81 is not reportable. T80.81 is the non-billable category that contains T80.810A.
A header stands for the whole family of codes beneath it and is not reported on a claim, so the choice is T80.810A or a sibling that matches the documentation. No Excludes1/Excludes2 relationship exists between these codes in the official tabular list.
Official guidance behind these answers
Section I.B.2 — Level of Detail in Coding · applies to: T80.81 and T80.810A
Diagnosis codes are to be used and reported at their highest number of characters available and to the highest level of specificity documented in the medical record. ICD-10-CM diagnosis codes are composed of codes with 3, 4, 5, 6 or 7 characters. Codes with three characters are included in ICD-10-CM as the heading of a category of codes that may be further subdivided by the use of fourth and/or fifth characters and/or sixth characters, which provide greater detail. A three-character code is to be used only if it is not further subdivided. A code is invalid if it has not been coded to the full number of characters required for that code, including the 7th character, if applicable.
ICD-10-CM Official Guidelines FY2027
Quoted from the ICD-10-CM Official Guidelines for Coding and Reporting in effect for the release shown. The tabular notes above are the code-level instruction; these sections are the convention that says how such a note is applied. Source document (CMS PDF) · Release and checksum
Side by side
Similar descriptions do not make codes interchangeable. The documentation and the official instructions decide which code applies.
Extravasation of vesicant agent
Extravasation of vesicant antineoplastic chemotherapy, initial encounter
- bone marrow transplant rejection (T86.01)
- febrile nonhemolytic transfusion reaction (R50.84)
- fluid overload due to transfusion (E87.71)
- posttransfusion purpura (D69.51)
- transfusion associated circulatory overload (TACO) (E87.71)
- transfusion (red blood cell) associated hemochromatosis (E83.111)
- transfusion related acute lung injury (TRALI) (J95.84)
- any encounters with medical care for postprocedural conditions in which no complications are present, such as:
- artificial opening status (Z93.-)
- closure of external stoma (Z43.-)
- fitting and adjustment of external prosthetic device (Z44.-)
- burns and corrosions from local applications and irradiation (T20-T32)
- complications of surgical procedures during pregnancy, childbirth and the puerperium (O00-O9A)
- mechanical complication of respirator [ventilator] (J95.850)
- poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4 or 6)
- postprocedural fever (R50.82)
- specified complications classified elsewhere, such as:
- cerebrospinal fluid leak from spinal puncture (G97.0)
- colostomy malfunction (K94.0-)
- disorders of fluid and electrolyte imbalance (E86-E87)
- functional disturbances following cardiac surgery (I97.0-I97.1)
- intraoperative and postprocedural complications of specified body systems (D78.-, E36.-, E89.-, G97.3-, G97.4, H59.3-, H59.-, H95.2-, H95.3, I97.4-, I97.5, J95.6-, J95.7, K91.6-, L76.-, M96.-, N99.-)
- ostomy complications (J95.0-, K94.-, N99.5-)
- postgastric surgery syndromes (K91.1)
- postlaminectomy syndrome NEC (M96.1)
- postmastectomy lymphedema syndrome (I97.2)
- postsurgical blind-loop syndrome (K91.2)
- ventilator associated pneumonia (J95.851)
- code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
- code(s) to identify the specified condition resulting from the complication
- code to identify devices involved and details of circumstances (Y62-Y82)
T80 Complications following infusion, transfusion and therapeutic injection
S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88)
- complications following perfusion
- Infiltration of vesicant agent
- complications following perfusion
- Infiltration of vesicant antineoplastic chemotherapy
- The appropriate 7th character is to be added to each code from category T80
No Excludes1, Code first and Code also note at either code.
Notes are the code’s own tabular entry, quoted as published. A note that names the other code is the one the verdict above rests on. In a row that differs, notes every code shares are dimmed.
Derived from the official CMS ICD-10-CM tabular data (FY2027). A coding-rule comparison, not billing advice: payer-specific edits and medical-necessity policy are outside its scope. All data sources