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T80.82 vs T86.5

T80.82 (Complication of immune effector cellular therapy) compared with T86.5 (Complications of stem cell transplant), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).

Can these codes be reported together?

Yes, when both are documented. T80.82 carries an Excludes2 note covering T86.5: “complication of stem cell transplant (T86.5)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

Side by side

T80.82Complication of immune effector cellular therapyT86.5Complications of stem cell transplant
Billing statusNon-billable header

Report instead: T80.82XA, T80.82XD, T80.82XS

Billable
ClassificationS00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88)S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88)
DefinitionComplication of immune effector cellular therapy is a non-billable ICD-10-CM category code (T80.82).Complications of stem cell transplant is a billable ICD-10-CM diagnosis code (T86.5).
7th characterThe appropriate 7th character is to be added to each code from category T80
Includes
complications following perfusion
Complication of chimeric antigen receptor (CAR-T) cell therapy
Complication of IEC therapy
Complications from stem cells from peripheral blood
Complications from stem cells from umbilical cord
Use additional code
code to identify the specific complication, such as:
cytokine release syndrome (D89.83-)
immune effector cell-associated neurotoxicity syndrome (G92.0-)
code to identify other transplant complications, such as:
graft-versus-host disease (D89.81-)
malignancy associated with organ transplant (C80.2)

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources