Z79.6 vs Z79.81
Z79.6 (Long term (current) use of immunomodulators and immunosuppressants) compared with Z79.81 (Long term (current) use of agents affecting estrogen receptors and estrogen levels), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).
Can these codes be reported together?
Yes, when both are documented. Z79.6 carries an Excludes2 note covering Z79.81: “long term (current) use of agents affecting estrogen receptors and estrogen levels (Z79.81-)”
Excludes2 marks distinct conditions — both may be reported when both are documented.
Side by side
| Z79.6Long term (current) use of immunomodulators and immunosuppressants | Z79.81Long term (current) use of agents affecting estrogen receptors and estrogen levels | |
|---|---|---|
| Billing status | Non-billable header | Non-billable header |
| Classification | Z00-Z99 — Factors Influencing Health Status and Contact with Health Services (Z00-Z99) | Z00-Z99 — Factors Influencing Health Status and Contact with Health Services (Z00-Z99) |
| Definition | Long term (current) use of immunomodulators and immunosuppressants is a non-billable ICD-10-CM category code (Z79.6). | Long term (current) use of agents affecting estrogen receptors and estrogen levels is a non-billable ICD-10-CM category code (Z79.81). |
| Includes | long term (current) drug use for prophylactic purposes | long term (current) drug use for prophylactic purposes |
| Use additional code | — | code, if applicable, to identify: estrogen receptor positive status (Z17.0) family history of breast cancer (Z80.3) |
| Code first | — | , if applicable: malignant neoplasm of breast (C50.-) |
Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources