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J0588 HCPCS Level II Code: Injection, incobotulinumtoxin a, 1 unit

Medicare Coverage & Payment

  • CMS short descriptor: Incobotulinumtoxin a
  • Medicare coverage: Carrier judgment (CMS coverage code C)
  • Payment category: Drugs (pricing indicator 51)
  • BETOS: O1E — Other drugs
  • Last CMS action effective: January 1, 2012

Source: CMS HCPCS Level II release. Coverage codes indicate how Medicare treats the code, not whether a specific claim will be paid; payer policy and documentation still govern.

Code Overview

Injection, incobotulinumtoxin a, 1 unit is a HCPCS Level II code (J0588). CMS assigns coverage code C — Carrier judgment. Short description: Incobotulinumtoxin a.

Summary composed by MedCoder from this code's official HCPCS Level II record. The tabular instructional notes themselves appear verbatim below.

Change history

  • 2012-01-01
    Added to the code set
    Injection, incobotulinumtoxin a, 1 unit

Drug products (NDC)

CMS ASP NDC-HCPCS Crosswalk · 2026 Q3

Medicare Part B payment limit (ASP + 6%): $5.29

00259-1605-01 — Xeomin — Merz Pharmaceuticals, LLC (size 1 × qty 1 (1 UNIT per billing unit))

00259-1610-01 — Xeomin — Merz Pharmaceuticals, LLC (size 1 × qty 1 (1 UNIT per billing unit))

00259-1620-01 — Xeomin — Merz Pharmaceuticals, LLC (size 1 × qty 1 (1 UNIT per billing unit))

46783-0160-01 — Xeomin — Merz North America, Inc. (size 1 × qty 1 (1 UNIT per billing unit))

46783-0161-01 — Xeomin — Merz North America, Inc. (size 1 × qty 1 (1 UNIT per billing unit))

From the CMS ASP NDC-HCPCS Crosswalk and Part B Payment Limit File. Payment limits apply per HCPCS billing code, not per package.

Contextual Map

Every relationship of J0588 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Nearest codes (35)

  • J0500 — Injection, dicyclomine hcl, up to 20 mg [Sibling]
  • J0515 — Injection, benztropine mesylate, per 1 mg [Sibling]
  • J0517 — Injection, benralizumab, 1 mg [Sibling]
  • J0520 — Injection, bethanechol chloride, myotonachol or urecholine, up to 5 mg [Sibling]
  • J0525 — Injection, cefotetan disodium, 10 mg [Sibling]
  • J0528 — Injection, fosfomycin disodium, 20 mg [Sibling]
  • J0558 — Injection, penicillin g benzathine and penicillin g procaine, 100,000 units [Sibling]
  • J0561 — Injection, penicillin g benzathine, 100,000 units [Sibling]
  • and 27 more

Change history

  • 2012-01-01 — Added to the code set [Change history]

Nearest Codes in This Family

Official HCPCS Level II classifications closest to J0588 in its code family, with their registry titles.

  • J0583 — Injection, bivalirudin, 1 mg
  • J0584 — Injection, burosumab-twza 1 mg
  • J0585 — Injection, onabotulinumtoxina, 1 unit
  • J0586 — Injection, abobotulinumtoxina, 5 units
  • J0587 — Injection, rimabotulinumtoxinb, 100 units
  • J0589 — Injection, daxibotulinumtoxina-lanm, 1 unit
  • J0591 — Injection, deoxycholic acid, 1 mg
  • J0592 — Injection, buprenorphine hydrochloride, 0.1 mg
  • J0593 — Injection, lanadelumab-flyo, 1 mg (code may be used for medicare when drug administered under direct supervision of a physician, not for use when drug is self-administered)
  • J0594 — injection, busulfan, 1 mg