J2469 HCPCS Level II Code: Injection, palonosetron hcl, 25 mcg
HCPCS Level II code, maintained by CMS. Not a CPT code: CPT (HCPCS Level I) is a separate AMA code set that MedCoder does not publish. About HCPCS Level II
Compare with another code for J2469Check this code on a claim
Code status: Valid code · October 2026. A valid code in the CMS HCPCS Level II October 2026 file. Valid is not covered or payable: Medicare payment and coverage are shown below in CMS’s own terms.
Coding at a Glance
- Drug products
- 22 NDC products
Medicare Coverage & Payment
- CMS short descriptor: Palonosetron hcl
- Medicare coverage: Carrier judgment (CMS coverage code C)
- Payment category: Drugs (pricing indicator 51)
- BETOS: O1E — Other drugs
- Last CMS action effective: January 1, 2024
Source: CMS HCPCS Level II release. Coverage codes indicate how Medicare treats the code, not whether a specific claim will be paid; payer policy and documentation still govern.
Coding context
Guidelines, coding notes, decision aids, relationships (with MS-DRG and CCSR classification), hierarchy, HCC, coverage and the context map: what a coder reaches for after the core. Each section names whether it is official source data, a MedCoder-derived relationship or MedCoder editorial.
Drug products (NDC)
CMS ASP NDC-HCPCS Crosswalk · 2026 Q4
Medicare Part B payment limit (ASP + 6%): $0.47
00409-2504-10 Palonosetron — Pfizer Inc (size 5 × qty 1 (25 MCG per billing unit))
00781-3312-75 Palonosetron — Sandoz Inc. (size 5 × qty 1 (25 MCG per billing unit))
00781-3312-95 Palonosetron — Sandoz Inc. (size 5 × qty 10 (25 MCG per billing unit))
00781-3415-75 Palonosetron — Sandoz Inc. (size 5 × qty 1 (25 MCG per billing unit))
00781-3415-95 Palonosetron HCl — Sandoz Inc. (size 5 × qty 10 (25 MCG per billing unit))
16714-0834-01 Palonosetron — Northstar RxLLC (size 5 × qty 1 (25 MCG per billing unit))
25021-0783-05 Palonosetron — Sagent Pharmaceuticals (size 5 × qty 1 (25 MCG per billing unit))
25021-0788-74 Palonosetron — Sagent Pharmaceuticals (size 5 × qty 5 (25 MCG per billing unit))
55150-0186-05 Palonosetron — Eugia US LLC (size 5 × qty 1 (25 MCG per billing unit))
60505-6193-01 Palonosetron — Apotex Corp (size 5 × qty 1 (25 MCG per billing unit))
60505-6193-04 Palonosetron HCl — Apotex Corp (size 5 × qty 10 (25 MCG per billing unit))
60505-6439-01 Palonosetron Hydrochloride — Apotex Corp (size 5 × qty 1 (25 MCG per billing unit))
63323-0673-05 Palonosetron — FreseniUS Kabi USA, LLC (size 5 × qty 1 (25 MCG per billing unit))
63323-0673-89 Palonosetron — FreseniUS Kabi USA, LLC (size 5 × qty 10 (25 MCG per billing unit))
67457-0317-25 Palonosetron — Mylan Institutional LLC (size 5 × qty 1 (25 MCG per billing unit))
68001-0355-25 Palonosetron — BluePoint Laboratories (size 5 × qty 1 (25 MCG per billing unit))
69543-0371-10 Palonosetron — Virtus Pharmaceuticals, LLC (size 5 × qty 10 (25 MCG per billing unit))
+2 more
From the CMS ASP NDC-HCPCS Crosswalk and Part B Payment Limit File. Payment limits apply per HCPCS billing code, not per package.
Contextual Map
Every relationship of J2469 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.
Nearest codes (20)
- J2400 — Injection, chloroprocaine hydrochloride, per 30 ml[Sibling]— CMS HCPCS Level II code set
- J2401 — Injection, chloroprocaine hydrochloride, per 1 mg[Sibling]— CMS HCPCS Level II code set
- J2402 — Injection, chloroprocaine hydrochloride (clorotekal), per 1 mg[Sibling]— CMS HCPCS Level II code set
- J2403 — Chloroprocaine hcl ophthalmic, 3% gel, 1 mg[Sibling]— CMS HCPCS Level II code set
- J2404 — Injection, nicardipine, 0.1 mg[Sibling]— CMS HCPCS Level II code set
- J2405 — Injection, ondansetron hydrochloride, per 1 mg[Sibling]— CMS HCPCS Level II code set
- J2406 — Injection, oritavancin (kimyrsa), 10 mg[Sibling]— CMS HCPCS Level II code set
- J2407 — Injection, oritavancin (orbactiv), 10 mg[Sibling]— CMS HCPCS Level II code set
- and 12 more
Change history
- January 1, 2005 — Added to the code set [Change history]— CMS release files (code change ledger)
Reference
Index terms and tables, published questions and FAQ, every source behind this page with its release and checksum, the date-of-service check and the complete change history.
Sources for this page
Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.
- Code, descriptors, coverage and pricing attributes Official source data
- CMS HCPCS Alpha-Numeric (ANWEB) release — October 2026 quarterly update Release, file and checksum · Publisher’s page
- Drug products Official source data
- CMS Medicare Part B Drug Average Sales Price (ASP) Pricing Files (cms.gov/medicare/payment/part-b-drugs/asp-pricing-files) -- the NDC-HCPCS crosswalk and Part B payment limit files — 2026 Q4 (October 2026 release); FDA National Drug Code Directory, product.txt and package.txt (accessdata.fda.gov/cder/ndctext.zip) — Snapshot retrieved 2026-08-24, loaded 2026-08-24 Release, file and checksum · Publisher’s page
- Change history and date-of-service validity Official source data
- CMS HCPCS quarterly update files, ingested into the change ledger Release, file and checksum · Publisher’s page
- Comparisons, relationships and the contextual map MedCoder-derived relationship
- Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears
- Summary and FAQ answers MedCoder editorial explanation
- Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.
Current data releases:ICD-10-CM FY2027 · ICD-10-PCS FY2027 · HCPCS October 2026 · MS-DRG v44 · Medicare Code Editor v44.0 · NCCI PTP Q4 2026 · MUE Q4 2026 · NCD code lists 2026-01 · LCD export September 28, 2026 · All releases and sources
Labels on this page: Official source data · MedCoder-derived relationship · MedCoder editorial explanation. How to read the labels · All data sources and release dates · CMS coding rules
Cite this page
Reference this page in a research guide, syllabus or article. The release is included because code content changes each year.
MedCoder.ai. "J2469 — Injection, palonosetron hcl, 25 mcg." HCPCS Level II October 2026. https://medcoder.ai/hcpcs/code/j2469-injection-palonosetron-hcl-25-mcg
Change history
- January 1, 2005Added to the code setInjection, palonosetron hcl, 25 mcgHCPCS 2005 changes
Nearest Codes in This Family
Official HCPCS Level II classifications closest to J2469 in its code family, with their registry titles.
- J2426 — Injection, paliperidone palmitate extended release (invega sustenna), 1 mg
- J2427 — Injection, paliperidone palmitate extended release (invega hafyera, or invega trinza), 1 mg
- J2428 — Injection, paliperidone palmitate extended release (erzofri), 1 mg
- J2430 — Injection, pamidronate disodium, per 30 mg
- J2440 — Injection, papaverine hcl, up to 60 mg
- J2460 — Injection, oxytetracycline hcl, up to 50 mg
- J2468 — Injection, palonosetron hydrochloride (posfrea), 25 micrograms
- J2470 — Injection, pantoprazole sodium, 40 mg
- J2471 — Injection, pantoprazole (hikma), not therapeutically equivalent to j2470, 40 mg
- J2472 — Injection, pantoprazole sodium in sodium chloride (baxter), 40 mg