S3846 HCPCS Level II Code: Genetic testing for hemoglobin e beta-thalassemia
HCPCS Level II code, maintained by CMS. Not a CPT code: CPT (HCPCS Level I) is a separate AMA code set that MedCoder does not publish. About HCPCS Level II
Medicare Coverage & Payment
- CMS short descriptor: Gene test beta-thalassemia
Source: CMS HCPCS Level II release. Coverage codes indicate how Medicare treats the code, not whether a specific claim will be paid; payer policy and documentation still govern.
Coding context
The comparisons, hierarchy, index entries, guidelines, relationships, risk-adjustment and coverage context a coder commonly needs. Each section names whether it is official source data, a MedCoder-derived relationship or MedCoder editorial.
Contextual Map
Every relationship of S3846 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.
Nearest codes (17)
- S3800 — Genetic testing for amyotrophic lateral sclerosis (als)[Sibling]— CMS HCPCS Level II code set
- S3840 — Dna analysis for germline mutations of the ret proto-oncogene for susceptibility to multiple endocrine neoplasia type 2[Sibling]— CMS HCPCS Level II code set
- S3841 — Genetic testing for retinoblastoma[Sibling]— CMS HCPCS Level II code set
- S3842 — Genetic testing for von hippel-lindau disease[Sibling]— CMS HCPCS Level II code set
- S3844 — Dna analysis of the connexin 26 gene (gjb2) for susceptibility to congenital, profound deafness[Sibling]— CMS HCPCS Level II code set
- S3845 — Genetic testing for alpha-thalassemia[Sibling]— CMS HCPCS Level II code set
- S3849 — Genetic testing for niemann-pick disease[Sibling]— CMS HCPCS Level II code set
- S3850 — Genetic testing for sickle cell anemia[Sibling]— CMS HCPCS Level II code set
- and 9 more
Change history
- July 1, 2003 — Added to the code set [Change history]— CMS release files (code change ledger)
Deep reference
Published questions and FAQ, every source behind this page with its release and checksum, the date-of-service check and the complete change history.
Sources for this page
Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.
- Code, descriptors, coverage and pricing attributes Official source data
- CMS HCPCS Alpha-Numeric (ANWEB) release — October 2026 quarterly update Release, file and checksum · Publisher’s page
- Change history and date-of-service validity Official source data
- CMS HCPCS quarterly update files, ingested into the change ledger Release, file and checksum · Publisher’s page
- Comparisons, relationships and the contextual map MedCoder structured relationship
- Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears
- Summary and FAQ answers MedCoder explanation
- Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.
Current data releases:ICD-10-CM FY2027 · ICD-10-PCS FY2027 · HCPCS October 2026 · MS-DRG v44 · Medicare Code Editor v44.0 · NCCI PTP Q4 2026 · MUE Q4 2026 · NCD code lists 2026-01 · LCD export September 20, 2026 · All releases and sources
Labels on this page: Official source data · MedCoder structured relationship · MedCoder explanation. How to read the labels · All data sources and release dates · CMS coding rules
Cite this page
Reference this page in a research guide, syllabus or article. The release is included because code content changes each year.
MedCoder.ai. "S3846 — Genetic testing for hemoglobin e beta-thalassemia." HCPCS Level II October 2026. https://medcoder.ai/hcpcs/code/s3846-genetic-testing-for-hemoglobin-e-beta-thalassemia
Change history
- July 1, 2003Added to the code setGenetic testing for hemoglobin e beta-thalassemiaHCPCS 2003 changes
Nearest Codes in This Family
Official HCPCS Level II classifications closest to S3846 in its code family, with their registry titles.
- S3840 — Dna analysis for germline mutations of the ret proto-oncogene for susceptibility to multiple endocrine neoplasia type 2
- S3841 — Genetic testing for retinoblastoma
- S3842 — Genetic testing for von hippel-lindau disease
- S3844 — Dna analysis of the connexin 26 gene (gjb2) for susceptibility to congenital, profound deafness
- S3845 — Genetic testing for alpha-thalassemia
- S3849 — Genetic testing for niemann-pick disease
- S3850 — Genetic testing for sickle cell anemia
- S3852 — Dna analysis for apoe epsilon 4 allele for susceptibility to alzheimer's disease
- S3853 — Genetic testing for myotonic muscular dystrophy
- S3854 — Gene expression profiling panel for use in the management of breast cancer treatment