I82
Embolism and thrombosis of other veins
Embolism and thrombosis of other veins (I82) is a clinical category encompassing venous thromboembolic events (VTE) that occur outside the portal system and primary superficial phlebitis. This category includes high-acuity conditions such as Budd-Chiari syndrome (hepatic vein obstruction), renal vein thrombosis, and both acute and chronic deep vein thrombosis (DVT) of the lower and upper extremities. These conditions are characterized by the formation of an intravascular blood clot (thrombus) that may obstruct blood flow or detach and travel to the lungs as a pulmonary embolism. The clinical significance ranges from localized pain and swelling to life-threatening organ dysfunction or systemic embolism, requiring careful diagnostic imaging and anticoagulation management.
Clinical Symptoms
- Localized edema (swelling) of the affected limb or region
- Erythema (redness) and warmth over the thrombosed vein
- Tenderness or pain along the venous path
- Visible distension of superficial collateral veins
- Phlegmasia cerulea dolens (severe blue discoloration in massive DVT)
- Abdominal or flank pain (characteristic of visceral or renal vein thrombosis)
- Hepatomegaly and ascites (characteristic of hepatic vein thrombosis)
- Hematuria (in the context of renal vein involvement)
- Dyspnea or chest pain (if secondary pulmonary embolism occurs)
Common Causes
- Endothelial injury from trauma, surgery, or indwelling venous catheters
- Venous stasis due to prolonged immobilization, obesity, or heart failure
- Malignancy (paraneoplastic hypercoagulability)
- Inherited thrombophilias such as Factor V Leiden or Prothrombin G20210A mutation
- Deficiencies in Protein C, Protein S, or Antithrombin III
- Acquired hypercoagulable states including Antiphospholipid Syndrome
- Pregnancy and the postpartum period
- Use of oral contraceptives or hormone replacement therapy
- Nephrotic syndrome (specifically increasing risk for renal vein thrombosis)
Documentation & Coding Tips
Distinguish between acute and chronic embolism or thrombosis to ensure precise ICD-10-CM selection.
Example: Patient presents with acute onset right-sided flank pain. Imaging confirms acute embolism and thrombosis of the right renal vein. History is negative for prior venous thromboembolism. Plan: Initiate systemic anticoagulation. Billing Focus: Identification of acute status and specific renal vein involvement. Risk Adjustment: Maps to HCC 108 for acute vascular disease, reflecting higher severity than chronic or non-specific conditions.
Billing Focus: Specifying the acute vs. chronic nature is mandatory for 4th and 5th character specificity in the I82 category.
Document the specific vein involved with anatomical precision to avoid the use of unspecified codes.
Example: Evaluation of a 55-year-old male with new-onset ascites. Doppler ultrasound reveals acute embolism and thrombosis of the hepatic vein, consistent with Budd-Chiari syndrome. No evidence of inferior vena cava involvement. Billing Focus: Anatomical site specificity (Hepatic vein). Risk Adjustment: Budd-Chiari (I82.0) is a high-acuity condition requiring intensive management, impacting medical necessity and risk scores.
Billing Focus: Anatomical specificity (e.g., SVC, IVC, renal, hepatic) is required to move beyond the general I82.90 code.
Explicitly state the presence or absence of associated complications such as infarction or organ failure.
Example: Acute embolism and thrombosis of the superior vena cava secondary to indwelling central venous catheter, resulting in SVC syndrome. Patient exhibits facial edema and venous distention. Billing Focus: Inclusion of SVC syndrome as a complication. Risk Adjustment: Presence of complications like SVC syndrome increases the complexity of the medical decision-making (MDM) and mortality risk assessment.
Billing Focus: Documenting complications supports the highest level of medical necessity for interventional procedures.
Clarify the laterality for paired venous structures like renal or iliac veins.
Example: Left renal vein thrombosis, acute, confirmed via CT angiography. Right renal vein remains patent. Patient has associated nephrotic syndrome. Billing Focus: Laterality (Left). Risk Adjustment: Laterality is often required for specific ICD-10-CM codes that map to different risk-adjusted categories or DRG weights in inpatient settings.
Billing Focus: ICD-10-CM specificity for renal veins (I82.3) requires identifying right vs. left.
Note the underlying etiology if known, such as malignancy-induced hypercoagulability or mechanical causes.
Example: Acute embolism and thrombosis of the inferior vena cava, infrarenal segment, likely secondary to compression by retroperitoneal mass (metastatic adenocarcinoma). Billing Focus: Identification of the thrombus as acute and the specific IVC segment. Risk Adjustment: Linking the thrombosis to an underlying malignancy identifies a high-risk comorbid state (MCC) in many payment models.
Billing Focus: Documenting the cause (e.g., neoplasm, catheter-related) provides clinical context that may support secondary coding.
Relevant CPT Codes
-
99214 - Office or other outpatient visit for the evaluation and management of an established patient, which requires a moderate level of medical decision making. When using total time on the date of the encounter for code selection, 30-39 minutes must be met or exceeded.
Typically used for follow-up of acute venous thrombosis where anticoagulation management and monitoring are required.
-
99204 - Office or other outpatient visit for the evaluation and management of a new patient, which requires a moderate level of medical decision making. When using total time on the date of the encounter for code selection, 45-59 minutes must be met or exceeded.
Initial consultation for newly diagnosed venous thrombosis requiring a detailed treatment plan and workup for etiology.
-
99213 - Office or other outpatient visit for the evaluation and management of an established patient, which requires a low level of medical decision making. When using total time on the date of the encounter for code selection, 20-29 minutes must be met or exceeded.
Used for stable patients on long-term anticoagulation with minimal complications.
-
93975 - Duplex scan of arterial inflow and venous outflow of abdominal, pelvic, scrotal contents and/or retroperitoneal organs; complete study
Primary diagnostic tool for identifying Budd-Chiari, renal vein thrombosis, or portal vein involvement.
-
36011 - Selective catheter placement, venous system; first order branch
Used in interventional procedures to access specific veins (like the renal or hepatic veins) for venography or thrombolysis.
-
37212 - Transcatheter therapy, venous infusion for thrombolysis, initial day
Specific procedure for treating extensive or organ-threatening venous thrombosis through direct drug infusion.
-
85379 - D-dimer; quantitative
Used as a screening tool or to support the diagnosis of acute thrombotic activity.
-
74177 - Computed tomography, abdomen and pelvis, with contrast material(s)
Gold standard for diagnosing IVC, renal, and hepatic vein thrombosis and assessing surrounding structures.
-
37187 - Percutaneous transcatheter mechanical thrombectomy, vein(s), including intraprocedural pharmacological thrombolytic injection and fluoroscopic guidance, initial vessel
Used for rapid removal of large clot burdens in major veins like the IVC.
-
93978 - Duplex scan of aorta, inferior vena cava, iliac vasculature, or bypass grafts; complete study
Specifically used to evaluate the patency and flow dynamics of the IVC.
Related Diagnoses
- I82.0 - Budd-Chiari syndrome
- I82.1 - Thrombophlebitis migrans
- I82.210 - Embolism and thrombosis of superior vena cava
- I82.220 - Embolism and thrombosis of inferior vena cava
- I82.3 - Embolism and thrombosis of renal vein
- I82.C11 - Acute embolism and thrombosis of right internal jugular vein
- I81 - Portal vein thrombosis
- I26.99 - Other pulmonary embolism without acute cor pulmonale
- I80.209 - Phlebitis and thrombophlebitis of unspecified deep vessels of unspecified lower extremity
- D68.51 - Activated protein C resistance