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A88.8 ICD-10-CM Code: Other specified viral infections of central nervous system

Compare with another code for A88.8Check this code on a claim

Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.

Coding at a Glance

Official instructions
5 Excludes1

What these terms mean →

Billable · FY2027A valid, specific ICD-10-CM code, reportable for dates of service in FY2027.

What you need to know

Source: CMS/NCHS Official ICD-10-CM tabular notes, quoted. From the CMS/NCHS tabular list for the release in force. A note the category or block publishes applies to this code too, and is marked with where it comes from.

Excludes1Not reported with this code unless documented as unrelated
  • viral encephalitis NOS (A86) (from A88)
  • viral meningitis NOS (A87.9) (from A88)
  • postpolio syndrome (G14) (from A80-A89)
  • sequelae of poliomyelitis (B91) (from A80-A89)

+1 more in Instructions

Where it sits Source: CMS/NCHS

Under:Chapter 1: Certain Infectious and Parasitic DiseasesA80-A89 Viral and prion infections of the central nervous systemA88 Other viral infections of central nervous system, not elsewhere classified

Most relevant related codes MedCoder-derived

Read off the official notes above and this code’s own position in the tabular list. Which to report is a documentation question; Compare shows the two side by side.

CompareCheck ClaimView Related Codes

Inpatient Payment Groups (MS-DRG)

Potential MS-DRG participation — not a DRG assignment.

MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v44, Appendix B.

  • MS-DRG 097 — NON-BACTERIAL INFECTION OF NERVOUS SYSTEM EXCEPT VIRAL MENINGITIS WITH MCC (MDC 01)
  • MS-DRG 098 — NON-BACTERIAL INFECTION OF NERVOUS SYSTEM EXCEPT VIRAL MENINGITIS WITH CC (MDC 01)
  • MS-DRG 099 — NON-BACTERIAL INFECTION OF NERVOUS SYSTEM EXCEPT VIRAL MENINGITIS WITHOUT CC/MCC (MDC 01)
  • MS-DRG 974 — HIV WITH MAJOR RELATED CONDITION WITH MCC (MDC 25)
  • MS-DRG 975 — HIV WITH MAJOR RELATED CONDITION WITH CC (MDC 25)
  • MS-DRG 976 — HIV WITH MAJOR RELATED CONDITION WITHOUT CC/MCC (MDC 25)

A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.

Coding instructions

Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for A88.8 in the official ICD-10-CM tabular list, quoted as published.

Source: CMS/CDC — ICD-10-CM Tabular ListRelease: FY2027Effective: October 1, 2026

Trace:FY2027 changesChange historyRelease, file and checksum

Notes without a marker are published on A88.8 itself; “inherited from” names the category or block whose note applies here.

Excludes1 — Not Coded Here

Conditions generally not reported together with this code (Excludes1) -- an error unless the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Coder workflow for A88.8

MedCoder structured workflow — derived from this code’s own official record

Before you code A88.8

  1. “Other” (NEC) means the condition is specified in the record but no dedicated code captures it. Confirm the documented form is not one a sibling code names before settling on A88.8; if the record states no specifics at all, the unspecified sibling applies instead. “Other” codes are for documented conditions the classification gives no specific code; “unspecified” codes are for records lacking the detail (Guidelines I.A.9.a, I.A.9.b).

    ReviewA88.0, A88.1

    See the relationships section · Guide: Other vs unspecified (NEC vs NOS) →

  2. Check the Excludes1 note: if the documentation supports a condition named there, do not simply proceed with A88.8. Excludes1 conditions are not reported together with this code unless the record shows they are unrelated (Guidelines I.A.12.a).

    See the official tabular notes

Choose the right path

  1. Does the documentation support a condition named in A88.8’s Excludes1 note?
    Yes → Do not simply proceed: review the excluded code. Both are reported only when the record shows the two conditions are unrelated.
    No → Continue.

    ReviewA86, A87.9, G14, B91, B94.1

Consider A88.8. Then confirm the code is valid for the date of service in the Verify section.

Documentation check

The provider’s diagnostic statement
Codes are assigned from the provider’s documented diagnosis, not from clinical criteria, test values or a medication list (Guidelines I.A.19).
Any detail beyond this code’s title
What the record states that a more specific code would capture — or its absence, which itself supports the unspecified code.

Official instructions as workflow

  • Excludes1 — check before selecting A88.8(5 notes)

    Coding workflow: If the documentation supports a condition named in this note, do not simply proceed with A88.8: the two are not reported together. The one exception is when the record shows the two conditions are unrelated to each other.

    CompareA86, A87.9, G14, B91, B94.1

    See the official tabular notes · Guidelines I.A.12.a

Coding decision scenarios

Pattern scenarios for this code’s structure — decision rules, not clinical cases

Documentation: Both the condition A88.8 describes and a condition named in its Excludes1 note are documented for the same encounter.

Coding question: Can both codes be reported?

Path: Review the Excludes1 note and the excluded code, and look for a provider statement on whether the two conditions are related.

Reason: Excludes1 means the two are not coded together; the exception is when the record shows the conditions are unrelated to each other (Guidelines I.A.12.a).

ReviewA86, A87.9, G14, B91, B94.1

Every row is derived from this code’s own record — its title, tabular notes, 7th-character family and same-category siblings — with fixed MedCoder wording; nothing is inferred about a patient. The official notes and guideline text are in the sections each row links to, and they control.

Don’t confuse A88.8 with…

MedCoder analysis — pairs from this code’s official notes, distinctions written by MedCoder

The codes most likely to be picked instead of A88.8 — named in its own official notes, or sharing its laterality or encounter family — with what separates them and which documentation moves the case. Each links to the full comparison.

  • A86— Excludes1 conflict (Excludes1 — generally not reported together)

    Not coded here — the tabular list excludes this pair for the same encounter.

    Not reported together with this code, except where the two conditions are documented as unrelated.

    What moves you there: Documentation of viral encephalitis NOS moves the case to A86; the two are not reported together unless documented as unrelated.

    Full comparison: A88.8 vs A86 →

  • A87.9— Excludes1 conflict (Excludes1 — generally not reported together)

    Not coded here — the tabular list excludes this pair for the same encounter.

    Not reported together with this code, except where the two conditions are documented as unrelated.

    What moves you there: Documentation of viral meningitis NOS moves the case to A87.9; the two are not reported together unless documented as unrelated.

    Full comparison: A88.8 vs A87.9 →

  • G14— Excludes1 conflict (Excludes1 — generally not reported together)

    Not coded here — the tabular list excludes this pair for the same encounter.

    Not reported together with this code, except where the two conditions are documented as unrelated.

    What moves you there: Documentation of postpolio syndrome moves the case to G14; the two are not reported together unless documented as unrelated.

    Full comparison: A88.8 vs G14 →

  • B91— Excludes1 conflict (Excludes1 — generally not reported together)

    Not coded here — the tabular list excludes this pair for the same encounter.

    Not reported together with this code, except where the two conditions are documented as unrelated.

    What moves you there: Documentation of sequelae of poliomyelitis moves the case to B91; the two are not reported together unless documented as unrelated.

    Full comparison: A88.8 vs B91 →

  • B94.1— Excludes1 conflict (Excludes1 — generally not reported together)

    Not coded here — the tabular list excludes this pair for the same encounter.

    Not reported together with this code, except where the two conditions are documented as unrelated.

    What moves you there: Documentation of sequelae of viral encephalitis moves the case to B94.1; the two are not reported together unless documented as unrelated.

    Full comparison: A88.8 vs B94.1 →

Relationships are read from this code's own official notes, its laterality siblings and its encounter family; the wording of each distinction is MedCoder editorial, and the documentation named in each “what moves you there” line is the official note phrase or sibling title itself. Source: CMS ICD-10-CM tabular instructional notes; ICD-10-CM Official Guidelines, Section I.A.12.a.

Coding context

Guidelines, coding notes, decision aids, relationships (with MS-DRG and CCSR classification), hierarchy, HCC, coverage and the context map: what a coder reaches for after the core. Each section names whether it is official source data, a MedCoder-derived relationship or MedCoder editorial.

Code Overview

Other specified viral infections of central nervous system is a billable ICD-10-CM diagnosis code (A88.8).

MedCoder summary Summary composed by MedCoder from this code's official ICD-10-CM record. The tabular instructional notes themselves appear verbatim below.

Verify Before Coding

  • CC as a secondary diagnosis (FY2027). Can raise the stay's MS-DRG severity tier.

From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.

Relationships & Classification

MedCoder-derived relationships — computed from published CMS and AHRQ datasets

MS-DRG Grouper Relationships (FY2027)

Potential MS-DRG participation — not a DRG assignment.

FY2027 MS-DRG: CC — Complication or Comorbidity. Reported as a secondary diagnosis, this code raises the stay's MS-DRG severity tier — except when the principal diagnosis is one of 188 clinically related codes on its CMS exclusion list. Does not count toward severity when the stay groups to DRGs 974-976 (HIV with Major Related Condition).

Named in the grouper logic of 6 MS-DRGs: DRG 097 (MDC 01), DRG 098 (MDC 01), DRG 099 (MDC 01), DRG 974 (MDC 25), DRG 975 (MDC 25), DRG 976 (MDC 25).

From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.

Clinical classification (AHRQ CCSR):NVS003 — Other specified CNS infection and poliomyelitis (default); INF008 — Viral infection.

Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.

Related Codes

Same clinical process (MS-DRG)

Acts as CC — raises the severity of other admissions. CMS groups these diagnoses into one MS-DRG principal-diagnosis exclusion process — a CC/MCC on this list never raises severity when the principal diagnosis is also on it.

A84.1 — Central European tick-borne encephalitis, A84.81 — Powassan virus disease, A84.89 — Other tick-borne viral encephalitis, A84.9 — Tick-borne viral encephalitis, unspecified, A85.0 — Enteroviral encephalitis, A85.1 — Adenoviral encephalitis, A85.2 — Arthropod-borne viral encephalitis, unspecified, A85.8 — Other specified viral encephalitis, A87.2 — Lymphocytic choriomeningitis, A88.0 — Enteroviral exanthematous fever [Boston exanthem], A92.1 — O'nyong-nyong fever, A92.2 — Venezuelan equine fever, A92.30 — West Nile virus infection, unspecified, A92.31 — West Nile virus infection with encephalitis, A92.32 — West Nile virus infection with other neurologic manifestation, A92.39 — West Nile virus infection with other complications, A92.4 — Rift Valley fever, A92.5 — Zika virus disease, A92.8 — Other specified mosquito-borne viral fevers, A93.0 — Oropouche virus disease, +167 more

Same clinical category (CCSR)

AHRQ's Clinical Classifications Software groups these diagnoses under the same clinical categories (Other specified CNS infection and poliomyelitis, Viral infection).

A80.30 — Acute paralytic poliomyelitis, unspecified, A80.39 — Other acute paralytic poliomyelitis, A80.4 — Acute nonparalytic poliomyelitis, A80.9 — Acute poliomyelitis, unspecified, A81.00 — Creutzfeldt-Jakob disease, unspecified, A81.01 — Variant Creutzfeldt-Jakob disease, A81.09 — Other Creutzfeldt-Jakob disease, A81.2 — Progressive multifocal leukoencephalopathy, A81.81 — Kuru, A81.82 — Gerstmann-Sträussler-Scheinker syndrome, A81.83 — Fatal familial insomnia, A81.89 — Other atypical virus infections of central nervous system, A81.9 — Atypical virus infection of central nervous system, unspecified, A82.0 — Sylvatic rabies, A82.1 — Urban rabies, A82.9 — Rabies, unspecified, A88.0 — Enteroviral exanthematous fever [Boston exanthem], A88.1 — Epidemic vertigo, A89 — Unspecified viral infection of central nervous system, G14 — Postpolio syndrome, +297 more

Same Index main term, other category

The ICD-10-CM Index to Diseases and Injuries files this code under the main term “Coxsackie”; these codes share that main term but sit in a different category of the Tabular List.

A08.39 — Other viral enteritis (enteritis), A87.0 — Enteroviral meningitis (meningitis), B08.5 — Enteroviral vesicular pharyngitis (pharyngitis), B33.0 — Epidemic myalgia (pleurodynia), B33.20 — Viral carditis, unspecified (carditis), B33.21 — Viral endocarditis (endocarditis), B33.22 — Viral myocarditis (myocarditis), B33.23 — Viral pericarditis (pericarditis), B33.8 — Other specified viral diseases (specific disease NEC), B34.1 — Enterovirus infection, unspecified, B97.11 — Coxsackievirus as the cause of diseases classified elsewhere (as cause of disease classified elsewhere)

Lab tests where this diagnosis supports Medicare coverage (NCD)

Medicare's National Coverage Determination (NCD) program lists this diagnosis as medical justification for these lab tests.

HIV Screening Test

Contextual Map

Every relationship of A88.8 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Hierarchy

Clinical classification (CCSR)

MS-DRG Grouper

MDC crossing

  • MDC 01 — Diseases and Disorders of the Nervous System[MDC crossing]: “Diseases and Disorders of the Nervous System — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs. 8,919 same-MDC procedures group here; browse them on the MDC page.”— CMS MS-DRG Definitions Manual · FY2027
  • MDC 25 — Human Immunodeficiency Virus Infections[MDC crossing]: “Human Immunodeficiency Virus Infections — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs.”— CMS MS-DRG Definitions Manual · FY2027

Index entries

  • Coxsackie (virus) (infection), central nervous system NEC[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2027
  • Disease, diseased, enteroviral, enterovirus NEC, central nervous system NEC[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2027
  • Infection, infected, infective (opportunistic), virus, viral NOS, central nervous system, enterovirus NEC[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2027
  • Infection, infected, infective (opportunistic), virus, viral NOS, central nervous system, specified NEC[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2027

Nearest codes

Change history

  • FY2016 — In the code set at ICD-10-CM adoption [Change history]— CMS release files (code change ledger) · icd10cm-fy2016

Reference

Index terms and tables, published questions and FAQ, every source behind this page with its release and checksum, the date-of-service check and the complete change history.

Indexed Clinical Terms (4)

Official source data — entries quoted as published, in the Index’s own lookup phrasing

Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code. These are alphabetic-index entries shown as the Index writes them — lookup phrasing, not necessarily the wording of a final diagnosis.

Sources for this page

Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.

Code, title, tabular notes and index terms Official source data
CMS/CDC ICD-10-CM FY2027 tabular list, index and tables, effective October 1, 2026 Release, file and checksum · Publisher’s page
Claim edits Official source data
CMS Definitions of Medicare Code Edits — v44.0 (October 2026) Release, file and checksum · Publisher’s page
Inpatient payment groups Official source data
CMS MS-DRG Definitions Manual (incl. Appendix B diagnosis index, Appendix C CC/MCC list, Appendix E procedure index) and IPPS Final Rule tables — v44 Release, file and checksum · Publisher’s page
Change history and date-of-service validity Official source data
CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page
Comparisons, relationships and the contextual map MedCoder-derived relationship
Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears
Summary and FAQ answers MedCoder editorial explanation
Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.

Current data releases:ICD-10-CM FY2027 · ICD-10-PCS FY2027 · HCPCS October 2026 · MS-DRG v44 · Medicare Code Editor v44.0 · NCCI PTP Q4 2026 · MUE Q4 2026 · NCD code lists 2026-01 · LCD export September 28, 2026 · All releases and sources

Labels on this page: Official source data · MedCoder-derived relationship · MedCoder editorial explanation. How to read the labels · All data sources and release dates · CMS coding rules

Cite this page

Reference this page in a research guide, syllabus or article. The release is included because code content changes each year.

MedCoder.ai. "A88.8 — Other specified viral infections of central nervous system." ICD-10-CM FY2027. https://medcoder.ai/icd10/code/a88.8-other-specified-viral-infections-of-central-nervous-system

Change history

  • FY2016 — October 1, 2015
    In the code set at ICD-10-CM adoption
    Other specified viral infections of central nervous system

No changes since FY2016 — additions, deletions, description changes and billable-status changes are tracked through FY2027, and none are recorded for this code. Note changes are tracked from FY2027 only.

Nearest Codes in This Family

Official ICD-10-CM classifications closest to A88.8 in its code family, with their registry titles.

View all codes in the A88 family