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D59.1 ICD-10-CM Code: Other autoimmune hemolytic anemias

Compare with another code for D59.1Check this code on a claim

Billing Status: NO. This is a non-billable ICD-10-CM code: report a more specific billable code beneath it.

Coding at a Glance

Tabular directives
3 Excludes2

Not billable · FY2027A non-billable heading in the tabular list: report a more specific code beneath it.

What you need to know

Source: CMS/NCHS Official ICD-10-CM tabular notes, quoted. From the CMS/NCHS tabular list for the release in force. A note the category or block publishes applies to this code too, and is marked with where it comes from.

Excludes2Not included here; may be reported together
  • Evans syndrome (D69.41)
  • hemolytic disease of newborn (P55.-)
  • paroxysmal cold hemoglobinuria (D59.6)

Where it sits Source: CMS/NCHS

Under:Chapter 3: Diseases of the Blood and Blood-forming Organs and Certain Disorders Involving the Immune MechanismD55-D59 Hemolytic anemiasD59 Acquired hemolytic anemia

Codes under D59.1 (5)

  • D59.10Autoimmune hemolytic anemia, unspecifiedBillable
  • D59.11Warm autoimmune hemolytic anemiaBillable
  • D59.12Cold autoimmune hemolytic anemiaBillable
  • D59.13Mixed type autoimmune hemolytic anemiaBillable
  • D59.19Other autoimmune hemolytic anemiaBillable

Most relevant related codes MedCoder-derived

Read off the official notes above and this code’s own position in the tabular list. Which to report is a documentation question; Compare shows the two side by side.

CompareCheck ClaimView Related Codes

Coding instructions

Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for D59.1 in the official ICD-10-CM tabular list, quoted as published.

Source: CMS/CDC — ICD-10-CM Tabular ListRelease: FY2027Effective: October 1, 2026

Trace:FY2027 changesChange historyRelease, file and checksum

Excludes2 — Not Included Here

Conditions not covered by this code, but which may be reported alongside it when both are present.

Coder workflow for D59.1

MedCoder structured workflow — derived from this code’s own official record

Before you code D59.1

  1. D59.1 is not reportable as written. Select the more specific code beneath it that the documentation supports. Codes are reported to the highest level of specificity the classification provides (Guidelines I.B.2).

    ReviewD59.10, D59.11, D59.12, D59.13, D59.19

    See the relationships section · Guide: How to choose an ICD-10-CM code →

Choose the right path

  1. Does the documentation support one of the more specific codes beneath D59.1?
    Yes → Select that code and continue the checks below on its own page.
    No → D59.1 cannot be reported as written. Where the codes beneath it include an unspecified code, that code applies when the record goes no further; otherwise query for the missing detail.

    ReviewD59.10, D59.11, D59.12, D59.13, D59.19

Report the code beneath D59.1 that the documentation supports, not D59.1 itself. Then confirm that code is valid for the date of service on its own page.

Documentation check

The provider’s diagnostic statement
Codes are assigned from the provider’s documented diagnosis, not from clinical criteria, test values or a medication list (Guidelines I.A.19).
Any detail beyond this code’s title
What the record states that a more specific code would capture — or its absence, which itself supports the unspecified code.

Official instructions as workflow

  • Excludes2 — not part of D59.1(3 notes)

    Coding workflow: The conditions named in this note are not included in D59.1. When the record documents both, both may be reported; the note is a boundary, not a prohibition.

    CompareD69.41, P55, D59.6

    See the official tabular notes · Guidelines I.A.12.b

Every row is derived from this code’s own record — its title, tabular notes, 7th-character family and same-category siblings — with fixed MedCoder wording; nothing is inferred about a patient. The official notes and guideline text are in the sections each row links to, and they control.

Don’t confuse D59.1 with…

MedCoder analysis — pairs from this code’s official notes, distinctions written by MedCoder

The codes most likely to be picked instead of D59.1 — named in its own official notes, or sharing its laterality or encounter family — with what separates them and which documentation moves the case. Each links to the full comparison.

  • D59.9— Specificity relationship (Review)

    Overlapping diagnoses in the same category.

    Overlapping codes in the same category — the documentation decides which is the more specific fit.

    What moves you there: A record that documents no more than “Acquired hemolytic anemia, unspecified” takes D59.9; specificity in the record moves it back here.

    Full comparison: D59.1 vs D59.9 →

  • D69.41— Excludes2 relationship (Informational)

    Distinct conditions — both may be reported.

    A distinct condition — both may be reported when both are documented.

    What moves you there: Documentation of Evans syndrome adds D69.41; it is not part of this code and both may be reported when both are documented.

    Full comparison: D59.1 vs D69.41 →

  • P55— Excludes2 relationship (Informational)

    Distinct conditions — both may be reported.

    A distinct condition — both may be reported when both are documented.

    What moves you there: Documentation of hemolytic disease of newborn adds P55; it is not part of this code and both may be reported when both are documented.

    Full comparison: D59.1 vs P55 →

  • D59.6— Excludes2 relationship (Informational)

    Distinct conditions — both may be reported.

    A distinct condition — both may be reported when both are documented.

    What moves you there: Documentation of paroxysmal cold hemoglobinuria adds D59.6; it is not part of this code and both may be reported when both are documented.

    Full comparison: D59.1 vs D59.6 →

Relationships are read from this code's own official notes, its laterality siblings and its encounter family; the wording of each distinction is MedCoder editorial, and the documentation named in each “what moves you there” line is the official note phrase or sibling title itself. Source: CMS ICD-10-CM tabular instructional notes; ICD-10-CM Official Guidelines, Section I.A.12.a.

Coding context

Guidelines, coding notes, decision aids, relationships (with MS-DRG and CCSR classification), hierarchy, HCC, coverage and the context map: what a coder reaches for after the core. Each section names whether it is official source data, a MedCoder-derived relationship or MedCoder editorial.

Code Overview

Other autoimmune hemolytic anemias is a non-billable ICD-10-CM category code (D59.1). A more specific billable subcode must be selected for claims submission.

MedCoder summary Summary composed by MedCoder from this code's official ICD-10-CM record. The tabular instructional notes themselves appear verbatim below.

Verify Before Coding

From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.

Relationships & Classification

MedCoder-derived relationships — computed from published CMS and AHRQ datasets

Other codes that name D59.1 or its code family, from the CMS ICD-10-CM tabular instructional notes. Tabular-note edges are stored at the code family level that carries each note.

Referenced by 1 Excludes1 note: R71 — Abnormality of red blood cells (via D59.-).

These codes’ tabular lists mark this diagnosis as mutually exclusive — not reported together unless the conditions are documented as unrelated.

Referenced by 23 Code First instructions across 3 chapters: I21.A1 — Myocardial infarction type 2 (via D59.-), M90.5 — Osteonecrosis in diseases classified elsewhere (via D59.-), T36 — Poisoning by, adverse effect of and underdosing of systemic antibiotics (via D59.-), T36-T39 — Antibiotics & Anti-infectives (T36-T39) (via D59.-), T36-T50 — Poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances (T36-T50) (via D59.-), T37 — Poisoning by, adverse effect of and underdosing of other systemic anti-infectives and antiparasitics (via D59.-), T38 — Poisoning by, adverse effect of and underdosing of hormones and their synthetic substitutes and antagonists, not elsewhere classified (via D59.-), T39 — Poisoning by, adverse effect of and underdosing of nonopioid analgesics, antipyretics and antirheumatics (via D59.-), T40 — Poisoning by, adverse effect of and underdosing of narcotics and psychodysleptics [hallucinogens] (via D59.-), T40-T41 — Analgesics & Antipyretics (T40-T41) (via D59.-), T41 — Poisoning by, adverse effect of and underdosing of anesthetics and therapeutic gases (via D59.-), T42 — Poisoning by, adverse effect of and underdosing of antiepileptic, sedative- hypnotic and antiparkinsonism drugs (via D59.-), T42-T43 — Anticonvulsants & Psychotropics (T42-T43) (via D59.-), T43 — Poisoning by, adverse effect of and underdosing of psychotropic drugs, not elsewhere classified (via D59.-), T44 — Poisoning by, adverse effect of and underdosing of drugs primarily affecting the autonomic nervous system (via D59.-), T44-T46 — Cardiovascular & Gastrointestinal (T44-T46) (via D59.-), T45 — Poisoning by, adverse effect of and underdosing of primarily systemic and hematological agents, not elsewhere classified (via D59.-), T46 — Poisoning by, adverse effect of and underdosing of agents primarily affecting the cardiovascular system (via D59.-), T47 — Poisoning by, adverse effect of and underdosing of agents primarily affecting the gastrointestinal system (via D59.-), T47-T50 — Hormones & Systemic Agents (T47-T50) (via D59.-), +3 more.

Each of these codes carries a Code First note naming this condition — when that code is reported, THIS code is sequenced first, ahead of it.

Clinical classification (AHRQ CCSR):BLD002 — Hemolytic anemia (default).

Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.

Related Codes

Same clinical category (CCSR)

AHRQ's Clinical Classifications Software groups these diagnoses under the same clinical category (Hemolytic anemia).

D56.4 — Hereditary persistence of fetal hemoglobin [HPFH], D56.5 — Hemoglobin E-beta thalassemia, D56.8 — Other thalassemias, D56.9 — Thalassemia, unspecified, D58.0 — Hereditary spherocytosis, D58.1 — Hereditary elliptocytosis, D58.2 — Other hemoglobinopathies, D58.8 — Other specified hereditary hemolytic anemias, D58.9 — Hereditary hemolytic anemia, unspecified, D59.0 — Drug-induced autoimmune hemolytic anemia, D59.10 — Autoimmune hemolytic anemia, unspecified, D59.11 — Warm autoimmune hemolytic anemia, D59.12 — Cold autoimmune hemolytic anemia, D59.13 — Mixed type autoimmune hemolytic anemia, D59.19 — Other autoimmune hemolytic anemia, D59.2 — Drug-induced nonautoimmune hemolytic anemia, D59.3 — Hemolytic-uremic syndrome, D59.30 — Hemolytic-uremic syndrome, unspecified, D59.31 — Infection-associated hemolytic-uremic syndrome, D59.32 — Hereditary hemolytic-uremic syndrome, +18 more

Contextual Map

Every relationship of D59.1 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Run D59.1 with these 12 related codes in Claim Check

Hierarchy

Excludes2

Referenced by Excludes1 notes

Referenced by Code First instructions (23)

Clinical classification (CCSR)

Nearest codes (18)

Change history (2)

Reference

Index terms and tables, published questions and FAQ, every source behind this page with its release and checksum, the date-of-service check and the complete change history.

Common coding questions

MedCoder editorial

Can D59.1 be billed directly?

No. D59.1 (Other autoimmune hemolytic anemias) is a non-billable ICD-10-CM category code. A more specific billable subcode must be selected based on clinical documentation.

Sources for this page

Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.

Code, title, tabular notes and index terms Official source data
CMS/CDC ICD-10-CM FY2027 tabular list, index and tables, effective October 1, 2026 Release, file and checksum · Publisher’s page
Claim edits Official source data
CMS Definitions of Medicare Code Edits — v44.0 (October 2026) Release, file and checksum · Publisher’s page
Change history and date-of-service validity Official source data
CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page
Comparisons, relationships and the contextual map MedCoder-derived relationship
Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears
Summary and FAQ answers MedCoder editorial explanation
Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.

Current data releases:ICD-10-CM FY2027 · ICD-10-PCS FY2027 · HCPCS October 2026 · MS-DRG v44 · Medicare Code Editor v44.0 · NCCI PTP Q4 2026 · MUE Q4 2026 · NCD code lists 2026-01 · LCD export September 28, 2026 · All releases and sources

Labels on this page: Official source data · MedCoder-derived relationship · MedCoder editorial explanation. How to read the labels · All data sources and release dates · CMS coding rules

Cite this page

Reference this page in a research guide, syllabus or article. The release is included because code content changes each year.

MedCoder.ai. "D59.1 — Other autoimmune hemolytic anemias." ICD-10-CM FY2027. https://medcoder.ai/icd10/code/d59.1-other-autoimmune-hemolytic-anemias

Change history

  • FY2021 — October 1, 2020
    Became a non-billable header
    FY2021 changes
  • FY2016 — October 1, 2015
    In the code set at ICD-10-CM adoption
    Other autoimmune hemolytic anemias

Nearest Codes in This Family

Official ICD-10-CM classifications closest to D59.1 in its code family, with their registry titles.

View all codes in the D59 family