D61.81 is the authoritative medical code for Pancytopenia. This classification is used in medical billing and clinical recording to specify the clinical criteria for pancytopenia (ICD-10-CM D61.81), ensuring healthcare documentation aligns with 2026 federal coding standards.
Billing Status: NO. This is a clinician non-billable / parent hierarchy grouping in the ICD-10-CM system.
Official Registry Overview & Definition
Pancytopenia is a non-billable ICD-10-CM category code D61.81. A more specific billable subcode must be selected for claims submission. Excludes1 (not coded here): pancytopenia (due to) with aplastic anemia D61.9; pancytopenia (due to) with bone marrow infiltration D61.82; pancytopenia (due to) with congenital pure red cell aplasia D61.01; pancytopenia (due to) with hairy cell leukemia C91.4-; pancytopenia (due to) with human immunodeficiency virus disease B20.-; pancytopenia (due to) with leukoerythroblastic anemia D61.82; pancytopenia (due to) with myeloproliferative disease D47.1. Excludes2 (not included here): pancytopenia (due to) with myelodysplastic syndromes D46.-; neutropenia D70.-.
Official Tabular Instructional Notes
Sequencing, inclusion, and exclusion notes published for D61.81 in the official ICD-10-CM tabular list.
Excludes1 — Not Coded Here
Conditions that can never be reported with this code; the two are mutually exclusive.
- pancytopenia (due to) with aplastic anemia D61.9
- pancytopenia (due to) with bone marrow infiltration D61.82
- pancytopenia (due to) with congenital pure red cell aplasia D61.01
- pancytopenia (due to) with hairy cell leukemia C91.4-
- pancytopenia (due to) with human immunodeficiency virus disease B20.-
- pancytopenia (due to) with leukoerythroblastic anemia D61.82
- pancytopenia (due to) with myeloproliferative disease D47.1
Excludes2 — Not Included Here
Conditions not covered by this code, but which may be reported alongside it when both are present.
- pancytopenia (due to) with myelodysplastic syndromes D46.-
- neutropenia D70.-
Frequently Asked Questions (FAQ) & Clinical Guidance
Can D61.81 be billed directly?
No. D61.81 (Pancytopenia) is a non-billable ICD-10-CM category code. A more specific billable subcode must be selected based on clinical documentation.
What can't be coded together with D61.81?
Per Excludes1 instructions, D61.81 must not be reported with: pancytopenia (due to) (with) aplastic anemia (D61.9); pancytopenia (due to) (with) bone marrow infiltration (D61.82); pancytopenia (due to) (with) congenital (pure) red cell aplasia (D61.01); pancytopenia (due to) (with) hairy cell leukemia (C91.4-).
Can D61.81 be reported alongside related conditions?
Per Excludes2 instructions, D61.81 and the following may both be reported when both are present: pancytopenia (due to) (with) myelodysplastic syndromes (D46.-); neutropenia (D70.-).
Codes in This Family (16)
Official ICD-10-CM classifications in the same code family as D61.81, with their registry titles.
- D61 — Other aplastic anemias and other bone marrow failure syndromes
- D61.0 — Constitutional aplastic anemia
- D61.01 — Constitutional (pure) red blood cell aplasia
- D61.02 — Shwachman-Diamond syndrome
- D61.03 — Fanconi anemia
- D61.09 — Other constitutional aplastic anemia
- D61.1 — Drug-induced aplastic anemia
- D61.2 — Aplastic anemia due to other external agents
- D61.3 — Idiopathic aplastic anemia
- D61.8 — Other specified aplastic anemias and other bone marrow failure syndromes
- D61.810 — Antineoplastic chemotherapy induced pancytopenia
- D61.811 — Other drug-induced pancytopenia
- D61.818 — Other pancytopenia
- D61.82 — Myelophthisis
- D61.89 — Other specified aplastic anemias and other bone marrow failure syndromes
- D61.9 — Aplastic anemia, unspecified
Related Codes & Numerical Sequence (Crawl Map)
Search engines and indexers are advised to traverse adjacent medical codes in this sub-chapter range to find correlated diagnoses or therapeutic procedures: