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D61.9 ICD-10-CM Code: Aplastic anemia, unspecified

Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.

Coding at a Glance

Tabular directives
2 inclusion terms · 1 Excludes2
Risk adjustment
CMS-HCC V22 category 46 · RxHCC V08 category 96

Inpatient Payment Groups (MS-DRG)

Potential MS-DRG participation — not a DRG assignment.

MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v43, Appendix B.

  • MS-DRG 808 — MAJOR HEMATOLOGICAL AND IMMUNOLOGICAL DIAGNOSES EXCEPT SICKLE CELL CRISIS AND COAGULATION DISORDERS WITH MCC (MDC 16)
  • MS-DRG 809 — MAJOR HEMATOLOGICAL AND IMMUNOLOGICAL DIAGNOSES EXCEPT SICKLE CELL CRISIS AND COAGULATION DISORDERS WITH CC (MDC 16)
  • MS-DRG 810 — MAJOR HEMATOLOGICAL AND IMMUNOLOGICAL DIAGNOSES EXCEPT SICKLE CELL CRISIS AND COAGULATION DISORDERS WITHOUT CC/MCC (MDC 16)

A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.

Coding instructions

Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for D61.9 in the official ICD-10-CM tabular list, quoted as published.

Source: CMS/CDC — ICD-10-CM Tabular ListRelease: FY2026Effective: October 1, 2025

Notes without a marker are published on D61.9 itself; “inherited from” names the category or block whose note applies here.

Inclusion Terms

Alternative terms the tabular list files under this code.

  • Hypoplastic anemia NOS
  • Medullary hypoplasia

Excludes2 — Not Included Here

Conditions not covered by this code, but which may be reported alongside it when both are present.

Source: inherited from D61

Coder workflow for D61.9

MedCoder structured workflow — derived from this code’s own official record

Before you code D61.9

  1. Unspecified does not mean incorrect. When the record gives no greater specificity, D61.9 may be the appropriate code. Check the record for detail that supports a more specific sibling. An unspecified code is for records that do not provide the detail a more specific code needs; a query, not an assumption, is the route to specificity (Guidelines I.A.9.b, I.B.18).

    ReviewD61.0, D61.1, D61.2, D61.3, D61.8

    See the relationships section · Guide: Other vs unspecified (NEC vs NOS) →

Choose the right path

  1. Does the record document the detail a more specific sibling code needs?
    Yes → Review the specific siblings in this subcategory.
    No → Continue — D61.9 is appropriate when the documentation goes no further.

    ReviewD61.0, D61.1, D61.2, D61.3, D61.8

Consider D61.9. Then confirm the code is valid for the date of service in the Verify section.

Documentation check

The provider’s diagnostic statement
Codes are assigned from the provider’s documented diagnosis, not from clinical criteria, test values or a medication list (Guidelines I.A.19).
Any detail beyond this code’s title
What the record states that a more specific sibling code would capture — or its absence, which itself supports the unspecified code.

Official instructions as workflow

  • Excludes2 — not part of D61.9(1 note)

    Coding workflow: The conditions named in this note are not included in D61.9. When the record documents both, both may be reported; the note is a boundary, not a prohibition.

    CompareD70

    See the official tabular notes · Guidelines I.A.12.b

Coding decision scenarios

Pattern scenarios for this code’s structure — decision rules, not clinical cases

Documentation: The provider documents the condition in the terms of this code’s title and records no further detail.

Coding question: Is a more specific sibling code supportable?

Path: Review the specific siblings in this subcategory and what each requires the record to state.

Reason: A more specific code needs documentation of the distinguishing element; without it the unspecified code is appropriate, and a provider query is the route to specificity (Guidelines I.A.9.b, I.B.18).

ReviewD61.0, D61.1, D61.2, D61.3, D61.8

Every row is derived from this code’s own record — its title, tabular notes, 7th-character family and same-category siblings — with fixed MedCoder wording; nothing is inferred about a patient. The official notes and guideline text are in the sections each row links to, and they control.

Code Overview

Aplastic anemia, unspecified is a billable ICD-10-CM diagnosis code (D61.9).

MedCoder summary Summary composed by MedCoder from this code's official ICD-10-CM record. The tabular instructional notes themselves appear verbatim below.

Indexed Clinical Terms (11)

Official source data — entries quoted as published, in the Index’s own lookup phrasing

Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code. These are alphabetic-index entries shown as the Index writes them — lookup phrasing, not necessarily the wording of a final diagnosis.

Official Coding Guidelines

No excerpt in the ICD-10-CM Official Guidelines names this code specifically. Its chapter carries only this chapter-wide note:

Chapter 3: Disease of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)

Reserved for future guideline expansion

Verify Before Coding

  • CC as a secondary diagnosis (FY2026). Can raise the stay's MS-DRG severity tier.

From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.

Relationships & Classification

MedCoder structured relationships — computed from published CMS and AHRQ datasets

Other codes that name D61.9 or its code family, from the CMS ICD-10-CM tabular instructional notes. Tabular-note edges are stored at the code family level that carries each note.

Referenced by 2 Excludes1 notes across 2 chapters: D61.81 — Pancytopenia, R71 — Abnormality of red blood cells (via D61.-).

These codes’ tabular lists mark this diagnosis as mutually exclusive — not reported together unless the conditions are documented as unrelated.

Referenced by 23 Code First instructions across 3 chapters: I21.A1 — Myocardial infarction type 2 (via D61.-), M90.5 — Osteonecrosis in diseases classified elsewhere (via D61.-), T36 — Poisoning by, adverse effect of and underdosing of systemic antibiotics (via D61.-), T36-T39 — Antibiotics & Anti-infectives (T36-T39) (via D61.-), T36-T50 — Poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances (T36-T50) (via D61.-), T37 — Poisoning by, adverse effect of and underdosing of other systemic anti-infectives and antiparasitics (via D61.-), T38 — Poisoning by, adverse effect of and underdosing of hormones and their synthetic substitutes and antagonists, not elsewhere classified (via D61.-), T39 — Poisoning by, adverse effect of and underdosing of nonopioid analgesics, antipyretics and antirheumatics (via D61.-), T40 — Poisoning by, adverse effect of and underdosing of narcotics and psychodysleptics [hallucinogens] (via D61.-), T40-T41 — Analgesics & Antipyretics (T40-T41) (via D61.-), T41 — Poisoning by, adverse effect of and underdosing of anesthetics and therapeutic gases (via D61.-), T42 — Poisoning by, adverse effect of and underdosing of antiepileptic, sedative- hypnotic and antiparkinsonism drugs (via D61.-), T42-T43 — Anticonvulsants & Psychotropics (T42-T43) (via D61.-), T43 — Poisoning by, adverse effect of and underdosing of psychotropic drugs, not elsewhere classified (via D61.-), T44 — Poisoning by, adverse effect of and underdosing of drugs primarily affecting the autonomic nervous system (via D61.-), T44-T46 — Cardiovascular & Gastrointestinal (T44-T46) (via D61.-), T45 — Poisoning by, adverse effect of and underdosing of primarily systemic and hematological agents, not elsewhere classified (via D61.-), T46 — Poisoning by, adverse effect of and underdosing of agents primarily affecting the cardiovascular system (via D61.-), T47 — Poisoning by, adverse effect of and underdosing of agents primarily affecting the gastrointestinal system (via D61.-), T47-T50 — Hormones & Systemic Agents (T47-T50) (via D61.-), +3 more.

Each of these codes carries a Code First note naming this condition — when that code is reported, THIS code is sequenced first, ahead of it.

MS-DRG Grouper Relationships (FY2026)

Potential MS-DRG participation — not a DRG assignment.

FY2026 MS-DRG: CC — Complication or Comorbidity. Reported as a secondary diagnosis, this code raises the stay's MS-DRG severity tier — except when the principal diagnosis is one of 110 clinically related codes on its CMS exclusion list.

Named in the grouper logic of 3 MS-DRGs: DRG 808 (MDC 16), DRG 809 (MDC 16), DRG 810 (MDC 16).

From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.

Clinical classification (AHRQ CCSR):BLD003 — Aplastic anemia (default).

Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.

Related Codes

Same clinical process (MS-DRG)

Acts as CC — raises the severity of other admissions. CMS groups these diagnoses into one MS-DRG principal-diagnosis exclusion process — a CC/MCC on this list never raises severity when the principal diagnosis is also on it.

D61.03 — Fanconi anemia, D61.09 — Other constitutional aplastic anemia, D61.1 — Drug-induced aplastic anemia, D61.2 — Aplastic anemia due to other external agents, D61.3 — Idiopathic aplastic anemia, D61.810 — Antineoplastic chemotherapy induced pancytopenia, D61.811 — Other drug-induced pancytopenia, D61.818 — Other pancytopenia, D61.82 — Myelophthisis, D61.89 — Other specified aplastic anemias and other bone marrow failure syndromes, D62 — Acute posthemorrhagic anemia, D64.0 — Hereditary sideroblastic anemia, D64.2 — Secondary sideroblastic anemia due to drugs and toxins, D64.3 — Other sideroblastic anemias, D64.4 — Congenital dyserythropoietic anemia, D64.81 — Anemia due to antineoplastic chemotherapy, D64.89 — Other specified anemias, D64.9 — Anemia, unspecified, D68.312 — Antiphospholipid antibody with hemorrhagic disorder, D68.51 — Activated protein C resistance, +89 more

Same clinical category (CCSR)

AHRQ's Clinical Classifications Software groups these diagnoses under the same clinical category (Aplastic anemia).

D61.03 — Fanconi anemia, D61.09 — Other constitutional aplastic anemia, D61.1 — Drug-induced aplastic anemia, D61.2 — Aplastic anemia due to other external agents, D61.3 — Idiopathic aplastic anemia, D61.810 — Antineoplastic chemotherapy induced pancytopenia, D61.811 — Other drug-induced pancytopenia, D61.818 — Other pancytopenia, D61.82 — Myelophthisis, D61.89 — Other specified aplastic anemias and other bone marrow failure syndromes, D63.0 — Anemia in neoplastic disease, D63.1 — Anemia in chronic kidney disease, D63.8 — Anemia in other chronic diseases classified elsewhere, D64.0 — Hereditary sideroblastic anemia, D64.1 — Secondary sideroblastic anemia due to disease, D64.2 — Secondary sideroblastic anemia due to drugs and toxins, D64.3 — Other sideroblastic anemias, D64.4 — Congenital dyserythropoietic anemia, D64.81 — Anemia due to antineoplastic chemotherapy, D64.89 — Other specified anemias, +7 more

Same Index main term, other category

The ICD-10-CM Index to Diseases and Injuries files this code under the main terms “Anemia”, “Hypoplasia, hypoplastic”, “Aleukia”, …; these codes share that main term but sit in a different category of the Tabular List.

D59.19 — Other autoimmune hemolytic anemia (Lederer's), D59.2 — Drug-induced nonautoimmune hemolytic anemia (hemolytic, due to, drugs), D59.4 — Other nonautoimmune hemolytic anemias (hemolytic, toxic), D59.6 — Hemoglobinuria due to hemolysis from other external causes (hemolytic, acquired, with hemoglobinuria NEC), D59.8 — Other acquired hemolytic anemias (hemolytic, acquired, specified type NEC), D59.9 — Acquired hemolytic anemia, unspecified (hemolytic, acute), D60.0 — Chronic acquired pure red cell aplasia (red cell, chronic), D60.1 — Transient acquired pure red cell aplasia (red cell, transient), D60.8 — Other acquired pure red cell aplasias (red cell, specified type NEC), D60.9 — Acquired pure red cell aplasia, unspecified (red cell), D62 — Acute posthemorrhagic anemia (blood loss, acute), D63.0 — Anemia in neoplastic disease (in, neoplastic disease), D63.1 — Anemia in chronic kidney disease (in, failure, kidney), D63.8 — Anemia in other chronic diseases classified elsewhere (intertropical), D64.0 — Hereditary sideroblastic anemia (sideroblastic, hereditary), D64.1 — Secondary sideroblastic anemia due to disease (sideroblastic, secondary, disease), D64.2 — Secondary sideroblastic anemia due to drugs and toxins (sideroblastic, secondary, drugs and toxins), D64.3 — Other sideroblastic anemias (sideroblastic), D64.4 — Congenital dyserythropoietic anemia (dyshematopoietic), D64.81 — Anemia due to antineoplastic chemotherapy (due to, antineoplastic chemotherapy), +178 more

Contextual Map

Every relationship of D61.9 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Run D61.9 with these 10 related codes in Claim Check

Hierarchy

Referenced by Excludes1 notes

  • D61.81 — Pancytopenia[Excludes1]: “pancytopenia (due to) (with) aplastic anemia (D61.9)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
  • R71 — Abnormality of red blood cells[Excludes1](via D61.-): “anemias (D50-D64)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026

Referenced by Code First instructions (23)

Clinical classification (CCSR)

MS-DRG Grouper

MDC crossing

  • MDC 16 — Diseases and Disorders of Blood, Blood Forming Organs and Immunologic Disorders[MDC crossing]: “Diseases and Disorders of Blood, Blood Forming Organs and Immunologic Disorders — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs. 1,614 same-MDC procedures group here; browse them on the MDC page.”— CMS MS-DRG Definitions Manual · FY2026

Index entries (11)

  • Aleukia, hemorrhagica[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound), aplastic[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound), hypoplasia, red blood cells[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound), hypoplastic (idiopathic)[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound), hypoproliferative (refractive)[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
  • Aplasia, bone marrow (myeloid)[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
  • Hypoplasia, hypoplastic, bone NOS, marrow[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
  • Hypoplasia, hypoplastic, medullary[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
  • and 3 more

Nearest codes (16)

Change history

  • FY2016 — In the code set at ICD-10-CM adoption [Change history]— CMS release files (code change ledger) · icd10cm-fy2016

Sources for this page

Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.

Code, title, tabular notes and index terms Official source data
CMS/CDC ICD-10-CM FY2026 tabular list, index and tables, effective October 1, 2025 Release, file and checksum · Publisher’s page
Coding guidelines Official source data
ICD-10-CM Official Guidelines for Coding and Reporting (FY2026), quoted by section Release, file and checksum · Publisher’s page
Claim edits Official source data
CMS Definitions of Medicare Code Edits — v43.1 (April 2026) Release, file and checksum · Publisher’s page
Inpatient payment groups Official source data
CMS MS-DRG Definitions Manual (incl. Appendix B diagnosis index, Appendix C CC/MCC list, Appendix E procedure index) and IPPS Final Rule tables — v43 Release, file and checksum · Publisher’s page
Change history and date-of-service validity Official source data
CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page
Comparisons, relationships and the contextual map MedCoder structured relationship
Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears
Summary and FAQ answers MedCoder explanation
Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.

Labels on this page: Official source data · MedCoder structured relationship · MedCoder explanation. How to read the labels · All data sources and release dates

Cite this page

Reference this page in a research guide, syllabus or article. The release is included because code content changes each year.

MedCoder.ai. "D61.9 — Aplastic anemia, unspecified." ICD-10-CM FY2026. https://medcoder.ai/icd10/code/d61.9-aplastic-anemia-unspecified

Change history

  • FY2016 — October 1, 2015
    In the code set at ICD-10-CM adoption
    Aplastic anemia, unspecified

No changes since FY2016 — additions, deletions, description changes and billable-status changes are tracked through FY2027 (effective October 1, 2026), and none are recorded for this code. Note changes are tracked from FY2027 only.

Nearest Codes in This Family

Official ICD-10-CM classifications closest to D61.9 in its code family, with their registry titles.

View all codes in the D61 family