E31 ICD-10-CM Code: Polyglandular dysfunction
Billing Status: NO. This is a clinician non-billable / parent hierarchy grouping in the ICD-10-CM system.
Coding at a Glance
- Tabular directives
- 5 Excludes1
Coding instructions
Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for E31 in the official ICD-10-CM tabular list, quoted as published.
Source: CMS/CDC — ICD-10-CM Tabular ListRelease: FY2026Effective: October 1, 2025
Notes without a marker are published on E31 itself; “inherited from” names the category or block whose note applies here.
Excludes1 — Not Coded Here
Conditions generally not reported together with this code (Excludes1) -- an error unless the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
- ataxia telangiectasia Louis-Bar
- dystrophia myotonica Steinert
- pseudohypoparathyroidism (E20.1) Compare E31 vs E20.1 →
- galactorrhea (N64.3) inherited from E20-E35Compare E31 vs N64.3 →
- gynecomastia (N62) inherited from E20-E35Compare E31 vs N62 →
Coder workflow for E31
MedCoder structured workflow — derived from this code’s own official record
Before you code E31
- E31 is not reportable as written. Select the more specific code beneath it that the documentation supports. Codes are reported to the highest level of specificity the classification provides (Guidelines I.B.2).
ReviewE31.0, E31.1, E31.2, E31.8, E31.9
See the relationships section · Guide: How to choose an ICD-10-CM code →
- Check the Excludes1 note: if the documentation supports a condition named there, do not simply proceed with E31. Excludes1 conditions are not reported together with this code unless the record shows they are unrelated (Guidelines I.A.12.a).
Choose the right path
- Does the documentation support one of the more specific codes beneath E31?
Yes → Select that code and continue the checks below on its own page.
No → E31 cannot be reported as written; query for the specificity its subcategory needs. - Does the documentation support a condition named in E31’s Excludes1 note?
Yes → Do not simply proceed: review the excluded code. Both are reported only when the record shows the two conditions are unrelated.
No → Continue.
Consider E31. Then confirm the code is valid for the date of service in the Verify section.
Documentation check
- The provider’s diagnostic statement
- Codes are assigned from the provider’s documented diagnosis, not from clinical criteria, test values or a medication list (Guidelines I.A.19).
Official instructions as workflow
Excludes1 — check before selecting E31(5 notes)
Coding workflow: If the documentation supports a condition named in this note, do not simply proceed with E31: the two are not reported together. The one exception is when the record shows the two conditions are unrelated to each other.
See the official tabular notes · Guidelines I.A.12.a
Coding decision scenarios
Pattern scenarios for this code’s structure — decision rules, not clinical cases
Documentation: Both the condition E31 describes and a condition named in its Excludes1 note are documented for the same encounter.
Coding question: Can both codes be reported?
Path: Review the Excludes1 note and the excluded code, and look for a provider statement on whether the two conditions are related.
Reason: Excludes1 means the two are not coded together; the exception is when the record shows the conditions are unrelated to each other (Guidelines I.A.12.a).
Every row is derived from this code’s own record — its title, tabular notes, 7th-character family and same-category siblings — with fixed MedCoder wording; nothing is inferred about a patient. The official notes and guideline text are in the sections each row links to, and they control.
Code Overview
MedCoder summary Summary composed by MedCoder from this code's official ICD-10-CM record. The tabular instructional notes themselves appear verbatim below.
Verify Before Coding
From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.
Relationships & Classification
MedCoder structured relationships — computed from published CMS and AHRQ datasets
Other codes that name E31 or its code family, from the CMS ICD-10-CM tabular instructional notes. Tabular-note edges are stored at the code family level that carries each note.
Referenced by 1 Code First instruction: G63 — Polyneuropathy in diseases classified elsewhere.
Each of these codes carries a Code First note naming this condition — when that code is reported, THIS code is sequenced first, ahead of it.
Contextual Map
Every relationship of E31 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.
Run E31 with these 6 related codes in Claim Check
Hierarchy
- E00-E89 — Chapter 4: Endocrine, Nutritional and Metabolic Diseases (E00-E89) (E00-E89)[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- E20-E35 — Disorders of other endocrine glands[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
Excludes1
- E20.1 — Pseudohypoparathyroidism[Excludes1]: “pseudohypoparathyroidism (E20.1)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- G11.3 — Cerebellar ataxia with defective DNA repair[Excludes1]: “ataxia telangiectasia [Louis-Bar] (G11.3)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- G71.11 — Myotonic muscular dystrophy[Excludes1]: “dystrophia myotonica [Steinert] (G71.11)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- N62 — Hypertrophy of breast[Excludes1]: “gynecomastia (N62)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- N64.3 — Galactorrhea not associated with childbirth[Excludes1]: “galactorrhea (N64.3)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
Referenced by Code First instructions
- G63 — Polyneuropathy in diseases classified elsewhere[Code First]: “endocrine disease, except diabetes (E00-E07, E15-E16, E20-E34)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
Nearest codes (9)
- E31.0 — Autoimmune polyglandular failure[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- E31.1 — Polyglandular hyperfunction[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- E31.2 — Multiple endocrine neoplasia [MEN] syndromes[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- E31.20 — Multiple endocrine neoplasia [MEN] syndrome, unspecified[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- E31.21 — Multiple endocrine neoplasia [MEN] type I[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- E31.22 — Multiple endocrine neoplasia [MEN] type IIA[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- E31.23 — Multiple endocrine neoplasia [MEN] type IIB[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- E31.8 — Other polyglandular dysfunction[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- and 1 more
Change history
- FY2016 — In the code set at ICD-10-CM adoption [Change history]— CMS release files (code change ledger) · icd10cm-fy2016
Common coding questions
Can E31 be billed directly?
No. E31 (Polyglandular dysfunction) is a non-billable ICD-10-CM category code. A more specific billable subcode must be selected based on clinical documentation.
Sources for this page
Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.
- Code, title, tabular notes and index terms Official source data
- CMS/CDC ICD-10-CM FY2026 tabular list, index and tables, effective October 1, 2025 Release, file and checksum · Publisher’s page
- Claim edits Official source data
- CMS Definitions of Medicare Code Edits — v43.1 (April 2026) Release, file and checksum · Publisher’s page
- Change history and date-of-service validity Official source data
- CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page
- Comparisons, relationships and the contextual map MedCoder structured relationship
- Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears
- Summary and FAQ answers MedCoder explanation
- Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.
Labels on this page: Official source data · MedCoder structured relationship · MedCoder explanation. How to read the labels · All data sources and release dates
Cite this page
Reference this page in a research guide, syllabus or article. The release is included because code content changes each year.
MedCoder.ai. "E31 — Polyglandular dysfunction." ICD-10-CM FY2026. https://medcoder.ai/icd10/code/e31-polyglandular-dysfunction
Change history
- FY2016 — October 1, 2015In the code set at ICD-10-CM adoptionPolyglandular dysfunction
No changes since FY2016 — additions, deletions, description changes and billable-status changes are tracked through FY2027 (effective October 1, 2026), and none are recorded for this code. Note changes are tracked from FY2027 only.
Nearest Codes in This Family
Official ICD-10-CM classifications closest to E31 in its code family, with their registry titles.
- E31.0 — Autoimmune polyglandular failure
- E31.1 — Polyglandular hyperfunction
- E31.2 — Multiple endocrine neoplasia [MEN] syndromes
- E31.20 — Multiple endocrine neoplasia [MEN] syndrome, unspecified
- E31.21 — Multiple endocrine neoplasia [MEN] type I
- E31.22 — Multiple endocrine neoplasia [MEN] type IIA
- E31.23 — Multiple endocrine neoplasia [MEN] type IIB
- E31.8 — Other polyglandular dysfunction
- E31.9 — Polyglandular dysfunction, unspecified