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F10.121 ICD-10-CM Code: Alcohol abuse with intoxication delirium

Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.

Coding at a Glance

Tabular directives
2 Excludes1 · 1 use-additional code
Risk adjustment
CMS-HCC V22 category 55

Inpatient Payment Groups (MS-DRG)

Potential MS-DRG participation — not a DRG assignment.

MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v43, Appendix B.

  • MS-DRG 894 — ALCOHOL, DRUG ABUSE OR DEPENDENCE, LEFT AMA (MDC 20)
  • MS-DRG 895 — ALCOHOL, DRUG ABUSE OR DEPENDENCE WITH REHABILITATION THERAPY (MDC 20)
  • MS-DRG 896 — ALCOHOL, DRUG ABUSE OR DEPENDENCE WITHOUT REHABILITATION THERAPY WITH MCC (MDC 20)
  • MS-DRG 897 — ALCOHOL, DRUG ABUSE OR DEPENDENCE WITHOUT REHABILITATION THERAPY WITHOUT MCC (MDC 20)

A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.

Coding instructions

Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for F10.121 in the official ICD-10-CM tabular list, quoted as published.

Source: CMS/CDC — ICD-10-CM Tabular ListRelease: FY2026Effective: October 1, 2025

Notes without a marker are published on F10.121 itself; “inherited from” names the category or block whose note applies here.

Excludes1 — Not Coded Here

Conditions generally not reported together with this code (Excludes1) -- an error unless the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Source: inherited from F10.1

Use Additional Code

Supplementary codes the tabular list directs you to add.

  • Use additional code for blood alcohol level, if applicable (Y90.-)

Source: inherited from F10

Coder workflow for F10.121

MedCoder structured workflow — derived from this code’s own official record

Before you code F10.121

  1. F10.121’s title joins a condition with an associated condition or complication. Confirm each component is documented. Where the classification presumes the link through the “with” convention, only a provider statement that the conditions are unrelated defeats it. A combination code is assigned only when it fully identifies the documented conditions; a required second code for the stage, type or manifestation is still reported when the notes ask for it (Guidelines I.B.9, I.A.15).

    Guide: Combination codes →

  2. Check the Excludes1 note: if the documentation supports a condition named there, do not simply proceed with F10.121. Excludes1 conditions are not reported together with this code unless the record shows they are unrelated (Guidelines I.A.12.a).

    See the official tabular notes

Choose the right path

  1. Does the documentation support a condition named in F10.121’s Excludes1 note?
    Yes → Do not simply proceed: review the excluded code. Both are reported only when the record shows the two conditions are unrelated.
    No → Continue.

    ReviewF10.2, F10.9

Consider F10.121. Then work the Use Additional Code note, and confirm the code is valid for the date of service in the Verify section.

Documentation check

The provider’s diagnostic statement
Codes are assigned from the provider’s documented diagnosis, not from clinical criteria, test values or a medication list (Guidelines I.A.19).
The associated condition or complication
Whether the associated condition the title names is documented; the “with” convention presumes some links, and a provider statement that the conditions are unrelated defeats it (Guidelines I.A.15).
The conditions the Use Additional Code note names
Reported with this code when documented; a conditional instruction (“if applicable”, “if known”) applies only when the record supports it.

Official instructions as workflow

  • Excludes1 — check before selecting F10.121(2 notes)

    Coding workflow: If the documentation supports a condition named in this note, do not simply proceed with F10.121: the two are not reported together. The one exception is when the record shows the two conditions are unrelated to each other.

    CompareF10.2, F10.9

    See the official tabular notes · Guidelines I.A.12.a

  • Use Additional Code — after identifying F10.121(1 note)

    Coding workflow: Check whether the documentation supports the additional code(s) the note names, and report them with F10.121 when it does. Where the instruction is conditional (“if applicable”, “if known”), it applies only when the record documents the condition.

    ReviewY90

    See the official tabular notes · Guidelines I.A.13

Coding decision scenarios

Pattern scenarios for this code’s structure — decision rules, not clinical cases

Documentation: Both the condition F10.121 describes and a condition named in its Excludes1 note are documented for the same encounter.

Coding question: Can both codes be reported?

Path: Review the Excludes1 note and the excluded code, and look for a provider statement on whether the two conditions are related.

Reason: Excludes1 means the two are not coded together; the exception is when the record shows the conditions are unrelated to each other (Guidelines I.A.12.a).

ReviewF10.2, F10.9

Documentation: Only one of the components this code’s title joins is documented.

Coding question: Is F10.121 supported?

Path: Review the code for the documented component on its own.

Reason: A combination code is assigned only when it fully identifies the documented conditions; otherwise the documented component takes its own code (Guidelines I.B.9).

Documentation: A condition the Use Additional Code note names is documented.

Coding question: Is a second code reported with F10.121?

Path: Review the Use Additional Code note and the code it names.

Reason: The additional code is reported when the record documents the condition; a conditional instruction applies only when its condition is met (Guidelines I.A.13).

ReviewY90

Every row is derived from this code’s own record — its title, tabular notes, 7th-character family and same-category siblings — with fixed MedCoder wording; nothing is inferred about a patient. The official notes and guideline text are in the sections each row links to, and they control.

Code Overview

Alcohol abuse with intoxication delirium is a billable ICD-10-CM diagnosis code (F10.121).

MedCoder summary Summary composed by MedCoder from this code's official ICD-10-CM record. The tabular instructional notes themselves appear verbatim below.

Indexed Clinical Terms (7)

Official source data — entries quoted as published, in the Index’s own lookup phrasing

Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code. These are alphabetic-index entries shown as the Index writes them — lookup phrasing, not necessarily the wording of a final diagnosis.

Official Coding Guidelines

Official source data — quoted verbatim from the CMS/NCHS Official Guidelines

Official source data — quoted verbatim from the CMS/NCHS Official Guidelines

Verbatim excerpts from the ICD-10-CM Official Guidelines for Coding and Reporting (CMS/NCHS) that govern this code.

Chapter 5: Mental, Behavioral and Neurodevelopmental disorders (F01 – F99)

1) In Remission Selection of codes describing “in remission” for categories F10-F19, Mental and behavioral disorders due to psychoactive substance use (categories F10-F19 with -.11, -.21, -.91) requires the provider’s clinical judgment and are assigned only on the basis of provider documentation (as defined in the Official Guidelines for Coding and Reporting), unless otherwise instructed by the classification.

Chapter 5: Mental, Behavioral and Neurodevelopmental disorders (F01 – F99)

5) Blood Alcohol Level A code from category Y90, Evidence of alcohol involvement determined by blood alcohol level, may be assigned when this information is documented and the patient’s provider has documented a condition classifiable to category F10, Alcohol related disorders. The blood alcohol level does not need to be documented by the patient’s provider in order for it to be coded.

Chapter 15: Pregnancy, Childbirth, and the Puerperium (O00-O9A)

1) Alcohol use during pregnancy, childbirth and the puerperium Codes under subcategory O99.31, Alcohol use complicating pregnancy, childbirth, and the puerperium, should be assigned for any pregnancy case when a patient uses alcohol during the pregnancy or postpartum. A secondary code from category F10, Alcohol related disorders, should also be assigned to identify manifestations of the alcohol use.

Verify Before Coding

  • CC as a secondary diagnosis (FY2026). Can raise the stay's MS-DRG severity tier.

From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.

Relationships & Classification

MedCoder structured relationships — computed from published CMS and AHRQ datasets

Other codes that name F10.121 or its code family, from the CMS ICD-10-CM tabular instructional notes. Tabular-note edges are stored at the code family level that carries each note.

Referenced by 3 Excludes1 notes across 2 chapters: F10.2 — Alcohol dependence (via F10.1.-), F10.9 — Alcohol use, unspecified (via F10.1.-), R41.3 — Other amnesia (via F10.-).

These codes’ tabular lists mark this diagnosis as mutually exclusive — not reported together unless the conditions are documented as unrelated.

Referenced by 31 Excludes2 notes across 3 chapters: F02 — Dementia in other diseases classified elsewhere (via F10.-), F06 — Other mental disorders due to known physiological condition (via F10.-), F06.0 — Psychotic disorder with hallucinations due to known physiological condition (via F10.-), F06.2 — Psychotic disorder with delusions due to known physiological condition (via F10.-), F06.3 — Mood disorder due to known physiological condition (via F10.-), F06.4 — Anxiety disorder due to known physiological condition (via F10.-), F55 — Abuse of non-psychoactive substances (via F10.-), F63 — Impulse disorders (via F10.-), F63.1 — Pyromania (via F10.-), R78 — Findings of drugs and other substances, not normally found in blood (via F10.-), T36 — Poisoning by, adverse effect of and underdosing of systemic antibiotics (via F10.-), T36-T39 — Antibiotics & Anti-infectives (T36-T39) (via F10.-), T36-T50 — Poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances (T36-T50) (via F10.-), T37 — Poisoning by, adverse effect of and underdosing of other systemic anti-infectives and antiparasitics (via F10.-), T38 — Poisoning by, adverse effect of and underdosing of hormones and their synthetic substitutes and antagonists, not elsewhere classified (via F10.-), T39 — Poisoning by, adverse effect of and underdosing of nonopioid analgesics, antipyretics and antirheumatics (via F10.-), T40 — Poisoning by, adverse effect of and underdosing of narcotics and psychodysleptics [hallucinogens] (via F10.-), T40-T41 — Analgesics & Antipyretics (T40-T41) (via F10.-), T41 — Poisoning by, adverse effect of and underdosing of anesthetics and therapeutic gases (via F10.-), T42 — Poisoning by, adverse effect of and underdosing of antiepileptic, sedative- hypnotic and antiparkinsonism drugs (via F10.-), +11 more.

These codes’ tabular lists name this diagnosis as distinct — both may be reported when both are documented.

Referenced by 46 Use Additional Code instructions across 5 chapters: C00 — Malignant neoplasm of lip (via F10.-), C01 — Malignant neoplasm of base of tongue (via F10.-), C02 — Malignant neoplasm of other and unspecified parts of tongue (via F10.-), C03 — Malignant neoplasm of gum (via F10.-), C04 — Malignant neoplasm of floor of mouth (via F10.-), C05 — Malignant neoplasm of palate (via F10.-), C06 — Malignant neoplasm of other and unspecified parts of mouth (via F10.-), C07 — Malignant neoplasm of parotid gland (via F10.-), C08 — Malignant neoplasm of other and unspecified major salivary glands (via F10.-), C09 — Malignant neoplasm of tonsil (via F10.-), C10 — Malignant neoplasm of oropharynx (via F10.-), C14 — Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx (via F10.-), C15 — Malignant neoplasm of esophagus (via F10.-), C16 — Malignant neoplasm of stomach (via F10.-), C22 — Malignant neoplasm of liver and intrahepatic bile ducts (via F10.-), C25 — Malignant neoplasm of pancreas (via F10.-), C32 — Malignant neoplasm of larynx (via F10.-), G31.84 — Mild cognitive impairment of uncertain or unknown etiology (via F10.-), G72.1 — Alcoholic myopathy (via F10.-), I60 — Nontraumatic subarachnoid hemorrhage (via F10.-), +26 more.

These codes instruct coders to additionally report this code when it applies.

Referenced by 2 Code Also instructions across 2 chapters: G31.2 — Degeneration of nervous system due to alcohol (via F10.-), I42.6 — Alcoholic cardiomyopathy (via F10.-).

These codes suggest coding this condition alongside when both are present.

MS-DRG Grouper Relationships (FY2026)

Potential MS-DRG participation — not a DRG assignment.

FY2026 MS-DRG: CC — Complication or Comorbidity. Reported as a secondary diagnosis, this code raises the stay's MS-DRG severity tier — except when the principal diagnosis is one of 463 clinically related codes on its CMS exclusion list.

Named in the grouper logic of 4 MS-DRGs: DRG 894 (MDC 20), DRG 895 (MDC 20), DRG 896 (MDC 20), DRG 897 (MDC 20).

From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.

Clinical classification (AHRQ CCSR):MBD017 — Alcohol-related disorders (default).

Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.

Related Codes

Same clinical category (CCSR)

AHRQ's Clinical Classifications Software groups these diagnoses under the same clinical category (Alcohol-related disorders).

F10.10 — Alcohol abuse, uncomplicated, F10.120 — Alcohol abuse with intoxication, uncomplicated, F10.129 — Alcohol abuse with intoxication, unspecified, F10.130 — Alcohol abuse with withdrawal, uncomplicated, F10.131 — Alcohol abuse with withdrawal delirium, F10.132 — Alcohol abuse with withdrawal with perceptual disturbance, F10.139 — Alcohol abuse with withdrawal, unspecified, F10.14 — Alcohol abuse with alcohol-induced mood disorder, F10.150 — Alcohol abuse with alcohol-induced psychotic disorder with delusions, F10.151 — Alcohol abuse with alcohol-induced psychotic disorder with hallucinations, F10.159 — Alcohol abuse with alcohol-induced psychotic disorder, unspecified, F10.180 — Alcohol abuse with alcohol-induced anxiety disorder, F10.181 — Alcohol abuse with alcohol-induced sexual dysfunction, F10.182 — Alcohol abuse with alcohol-induced sleep disorder, F10.188 — Alcohol abuse with other alcohol-induced disorder, F10.19 — Alcohol abuse with unspecified alcohol-induced disorder, F10.20 — Alcohol dependence, uncomplicated, F10.220 — Alcohol dependence with intoxication, uncomplicated, F10.221 — Alcohol dependence with intoxication delirium, F10.229 — Alcohol dependence with intoxication, unspecified, +61 more

Same Index main term, other category

The ICD-10-CM Index to Diseases and Injuries files this code under the main terms “Abuse”, “Delirium, delirious”, “Alcohol, alcoholic, alcohol-induced”; these codes share that main term but sit in a different category of the Tabular List.

E52 — Niacin deficiency [pellagra] (pellagra), F05 — Delirium due to known physiological condition (puerperal), F11.10 — Opioid abuse, uncomplicated (drug NEC, opioid), F11.11 — Opioid abuse, in remission (drug NEC, opioid, in remission), F11.120 — Opioid abuse with intoxication, uncomplicated (drug NEC, opioid, with, intoxication, uncomplicated), F11.121 — Opioid abuse with intoxication delirium (drug NEC, opioid, with, intoxication, with, delirium), F11.122 — Opioid abuse with intoxication with perceptual disturbance (drug NEC, opioid, with, intoxication, with, perceptual disturbance), F11.129 — Opioid abuse with intoxication, unspecified (drug NEC, opioid, with, intoxication), F11.13 — Opioid abuse with withdrawal (drug NEC, opioid, with, withdrawal), F11.14 — Opioid abuse with opioid-induced mood disorder (drug NEC, opioid, with, mood disorder), F11.150 — Opioid abuse with opioid-induced psychotic disorder with delusions (drug NEC, opioid, with, psychosis, delusions), F11.151 — Opioid abuse with opioid-induced psychotic disorder with hallucinations (drug NEC, opioid, with, psychosis, hallucinations), F11.159 — Opioid abuse with opioid-induced psychotic disorder, unspecified (drug NEC, opioid, with, psychosis), F11.181 — Opioid abuse with opioid-induced sexual dysfunction (drug NEC, opioid, with, sexual dysfunction), F11.182 — Opioid abuse with opioid-induced sleep disorder (drug NEC, opioid, with, sleep disorder), F11.188 — Opioid abuse with other opioid-induced disorder (drug NEC, opioid, with, other specified disorder), F11.19 — Opioid abuse with unspecified opioid-induced disorder (drug NEC, opioid, with, unspecified disorder), F11.221 — Opioid dependence with intoxication delirium (due to, opioid intoxication, in, dependence), F11.921 — Opioid use, unspecified with intoxication delirium (due to, opioid intoxication), F12.10 — Cannabis abuse, uncomplicated (drug NEC, cannabis), +140 more

Lab tests where this diagnosis supports Medicare coverage (NCD)

Medicare's National Coverage Determination (NCD) program lists this diagnosis as medical justification for these lab tests.

Gamma-glutamyl Transferase (GGT) Test

Contextual Map

Every relationship of F10.121 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Run F10.121 with these 21 related codes in Claim Check

Hierarchy

Referenced by Excludes1 notes

  • F10.2 — Alcohol dependence[Excludes1](via F10.1.-): “alcohol abuse (F10.1-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
  • F10.9 — Alcohol use, unspecified[Excludes1](via F10.1.-): “alcohol abuse (F10.1-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
  • R41.3 — Other amnesia[Excludes1](via F10.-): “amnestic syndrome due to psychoactive substance use (F10-F19 with 5th character .6)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026

Referenced by Excludes2 notes (31)

Referenced by Use Additional Code instructions (46)

Referenced by Code Also instructions

Clinical classification (CCSR)

MS-DRG Grouper

MDC crossing

  • MDC 20 — Alcohol or Drug Use or Induced Organic Mental Disorders[MDC crossing]: “Alcohol or Drug Use or Induced Organic Mental Disorders — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs. 35 same-MDC procedures group here; browse them on the MDC page.”— CMS MS-DRG Definitions Manual · FY2026

Index entries

  • Abuse, alcohol (non-dependent), with, intoxication, with delirium[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
  • Alcohol, alcoholic, alcohol-induced, delirium (acute) (tremens) (withdrawal), abuse, with intoxication[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
  • Alcohol, alcoholic, alcohol-induced, delirium (acute) (tremens) (withdrawal), with intoxication, in, abuse[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
  • Alcohol, alcoholic, alcohol-induced, intoxication (acute) (without dependence), with, delirium[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
  • Delirium, delirious (acute or subacute) (not alcohol- or drug-induced), alcoholic (acute) (tremens) (withdrawal), with intoxication, in, abuse[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
  • Delirium, delirious (acute or subacute) (not alcohol- or drug-induced), due to (secondary to), alcohol, intoxication, in, abuse[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
  • Disorder (of), alcohol use, mild, with, alcohol intoxication, delirium[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026

Nearest codes (40)

Change history

  • FY2016 — In the code set at ICD-10-CM adoption [Change history]— CMS release files (code change ledger) · icd10cm-fy2016

Sources for this page

Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.

Code, title, tabular notes and index terms Official source data
CMS/CDC ICD-10-CM FY2026 tabular list, index and tables, effective October 1, 2025 Release, file and checksum · Publisher’s page
Coding guidelines Official source data
ICD-10-CM Official Guidelines for Coding and Reporting (FY2026), quoted by section Release, file and checksum · Publisher’s page
Claim edits Official source data
CMS Definitions of Medicare Code Edits — v43.1 (April 2026) Release, file and checksum · Publisher’s page
Inpatient payment groups Official source data
CMS MS-DRG Definitions Manual (incl. Appendix B diagnosis index, Appendix C CC/MCC list, Appendix E procedure index) and IPPS Final Rule tables — v43 Release, file and checksum · Publisher’s page
Change history and date-of-service validity Official source data
CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page
Comparisons, relationships and the contextual map MedCoder structured relationship
Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears
Summary and FAQ answers MedCoder explanation
Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.

Labels on this page: Official source data · MedCoder structured relationship · MedCoder explanation. How to read the labels · All data sources and release dates

Cite this page

Reference this page in a research guide, syllabus or article. The release is included because code content changes each year.

MedCoder.ai. "F10.121 — Alcohol abuse with intoxication delirium." ICD-10-CM FY2026. https://medcoder.ai/icd10/code/f10.121-alcohol-abuse-with-intoxication-delirium

Change history

  • FY2016 — October 1, 2015
    In the code set at ICD-10-CM adoption
    Alcohol abuse with intoxication delirium

No changes since FY2016 — additions, deletions, description changes and billable-status changes are tracked through FY2027 (effective October 1, 2026), and none are recorded for this code. Note changes are tracked from FY2027 only.

Nearest Codes in This Family

Official ICD-10-CM classifications closest to F10.121 in its code family, with their registry titles.

View all codes in the F10 family