F52.4 ICD-10-CM Code: Premature ejaculation

Coding instructions

Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for F52.4 in the official ICD-10-CM tabular list, quoted as published.

Source: CMS/CDC — ICD-10-CM Tabular ListRelease: FY2026Effective: October 1, 2025

Notes without a marker are published on F52.4 itself; “inherited from” names the category or block whose note applies here.

Coder workflow for F52.4

MedCoder structured workflow — derived from this code’s own official record

Documentation check

The provider’s diagnostic statement

Codes are assigned from the provider’s documented diagnosis, not from clinical criteria, test values or a medication list (Guidelines I.A.19).

Official instructions as workflow

• Excludes2 — not part of F52.4(1 note)

  Coding workflow: The conditions named in this note are not included in F52.4. When the record documents both, both may be reported; the note is a boundary, not a prohibition.

  CompareF48.8

  See the official tabular notes · Guidelines I.A.12.b

Every row is derived from this code’s own record — its title, tabular notes, 7th-character family and same-category siblings — with fixed MedCoder wording; nothing is inferred about a patient. The official notes and guideline text are in the sections each row links to, and they control.

Indexed Clinical Terms (7)

Official source data — entries quoted as published, in the Index’s own lookup phrasing

Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code. These are alphabetic-index entries shown as the Index writes them — lookup phrasing, not necessarily the wording of a final diagnosis.

• Dysfunction, ejaculatory, premature
• Dysfunction, psychosexual, with, premature ejaculation
• Dysfunction, sexual (due to), male, ejaculatory, premature
• Dysfunction, sexual (due to), male, psychogenic, premature ejaculation
• Dysfunction, sexual (due to), premature ejaculation
• Ejaculation, premature
• Premature, ejaculation

Don’t confuse F52.4 with…

MedCoder analysis — pairs from this code’s official notes, distinctions written by MedCoder

The codes most likely to be picked instead of F52.4 — named in its own official notes, or sharing its laterality or encounter family — with what separates them and which documentation moves the case. Each links to the full comparison.

• F52.9— Specificity relationship (Review)

  Overlapping diagnoses in the same category.

  Overlapping codes in the same category — the documentation decides which is the more specific fit.

  What moves you there: A record that documents no more than “Unspecified sexual dysfunction not due to a substance or known physiological condition” takes F52.9; specificity in the record moves it back here.

  Full comparison: F52.4 vs F52.9 →

• F48.8— Excludes2 relationship (Informational)

  Distinct conditions — both may be reported.

  A distinct condition — both may be reported when both are documented.

  What moves you there: Documentation of Dhat syndrome adds F48.8; it is not part of this code and both may be reported when both are documented.

  Full comparison: F52.4 vs F48.8 →

Relationships are read from this code's own official notes, its laterality siblings and its encounter family; the wording of each distinction is MedCoder editorial, and the documentation named in each “what moves you there” line is the official note phrase or sibling title itself. Source: CMS ICD-10-CM tabular instructional notes; ICD-10-CM Official Guidelines, Section I.A.12.a.

Verify Before Coding

• No Medicare Code Editor or MS-DRG Definitions Manual restrictions apply to this code.

From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.

Relationships & Classification

MedCoder structured relationships — computed from published CMS and AHRQ datasets

Other codes that name F52.4 or its code family, from the CMS ICD-10-CM tabular instructional notes. Tabular-note edges are stored at the code family level that carries each note.

Referenced by 2 Excludes1 notes: N53 — Other male sexual dysfunction (via F52.-), N53.1 — Ejaculatory dysfunction.

These codes’ tabular lists mark this diagnosis as mutually exclusive — not reported together unless the conditions are documented as unrelated.

Referenced by 1 Excludes2 note: F45 — Somatoform disorders (via F52.-).

These codes’ tabular lists name this diagnosis as distinct — both may be reported when both are documented.

MS-DRG Grouper Relationships (FY2026)

Potential MS-DRG participation — not a DRG assignment.

FY2026 MS-DRG: not on the CMS CC/MCC list — as a secondary diagnosis this code does not change MS-DRG severity for that release.

Named in the grouper logic of 1 MS-DRG: DRG 887 (MDC 19).

From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.

Clinical classification (AHRQ CCSR):MBD013 — Miscellaneous mental and behavioral disorders/conditions (default).

Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.

Related Codes

Same clinical category (CCSR)

AHRQ's Clinical Classifications Software groups these diagnoses under the same clinical category (Miscellaneous mental and behavioral disorders/conditions).

F07.9 — Unspecified personality and behavioral disorder due to known physiological condition, F09 — Unspecified mental disorder due to known physiological condition, F48.8 — Other specified nonpsychotic mental disorders, F48.9 — Nonpsychotic mental disorder, unspecified, F52.0 — Hypoactive sexual desire disorder, F52.1 — Sexual aversion disorder, F52.21 — Male erectile disorder, F52.22 — Female sexual arousal disorder, F52.31 — Female orgasmic disorder, F52.32 — Male orgasmic disorder, F52.5 — Vaginismus not due to a substance or known physiological condition, F52.6 — Dyspareunia not due to a substance or known physiological condition, F52.8 — Other sexual dysfunction not due to a substance or known physiological condition, F52.9 — Unspecified sexual dysfunction not due to a substance or known physiological condition, F54 — Psychological and behavioral factors associated with disorders or diseases classified elsewhere, F55.0 — Abuse of antacids, F55.1 — Abuse of herbal or folk remedies, F55.2 — Abuse of laxatives, F55.3 — Abuse of steroids or hormones, F55.4 — Abuse of vitamins, +32 more

Same Index main term, other category

The ICD-10-CM Index to Diseases and Injuries files this code under the main terms “Dysfunction”, “Premature”; these codes share that main term but sit in a different category of the Tabular List.

F14.181 — Cocaine abuse with cocaine-induced sexual dysfunction (sexual, cocaine, in, abuse), F14.281 — Cocaine dependence with cocaine-induced sexual dysfunction (sexual, cocaine, in, dependence), F14.981 — Cocaine use, unspecified with cocaine-induced sexual dysfunction (sexual, cocaine), F15.181 — Other stimulant abuse with stimulant-induced sexual dysfunction (sexual, amphetamine, in, abuse), F15.281 — Other stimulant dependence with stimulant-induced sexual dysfunction (sexual, amphetamine, in, dependence), F15.981 — Other stimulant use, unspecified with stimulant-induced sexual dysfunction (sexual, amphetamine), F19.181 — Other psychoactive substance abuse with psychoactive substance-induced sexual dysfunction (sexual, psychoactive substances NEC, in, abuse), F19.281 — Other psychoactive substance dependence with psychoactive substance-induced sexual dysfunction (sexual, psychoactive substances NEC, in, dependence), F19.981 — Other psychoactive substance use, unspecified with psychoactive substance-induced sexual dysfunction (sexual, psychoactive substances NEC), F45.8 — Other somatoform disorders (colon, psychogenic), F59 — Unspecified behavioral syndromes associated with physiological disturbances and physical factors (psychophysiologic), G31.2 — Degeneration of nervous system due to alcohol (autonomic, due to alcohol), G93.89 — Other specified disorders of brain (cerebral), H02.881 — Meibomian gland dysfunction right upper eyelid (meibomian gland, of eyelid, right, upper), H02.882 — Meibomian gland dysfunction right lower eyelid (meibomian gland, of eyelid, right, lower), H02.883 — Meibomian gland dysfunction of right eye, unspecified eyelid (meibomian gland, of eyelid, right), H02.884 — Meibomian gland dysfunction left upper eyelid (meibomian gland, of eyelid, left, upper), H02.885 — Meibomian gland dysfunction left lower eyelid (meibomian gland, of eyelid, left, lower), H02.886 — Meibomian gland dysfunction of left eye, unspecified eyelid (meibomian gland, of eyelid, left), H02.889 — Meibomian gland dysfunction of unspecified eye, unspecified eyelid (meibomian gland, of eyelid), +118 more

Contextual Map

Every relationship of F52.4 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Run F52.4 with these 3 related codes in Claim Check

Hierarchy

• F01-F99 — Chapter 5: Mental, Behavioral and Neurodevelopmental Disorders (F01-F99) (F01-F99)[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• F50-F59 — Behavioral syndromes associated with physiological disturbances and physical factors[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2026

Referenced by Excludes1 notes

• N53 — Other male sexual dysfunction[Excludes1](via F52.-): “psychogenic sexual dysfunction (F52.-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• N53.1 — Ejaculatory dysfunction[Excludes1]: “premature ejaculation (F52.4)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026

Referenced by Excludes2 notes

• F45 — Somatoform disorders[Excludes2](via F52.-): “sexual dysfunction, not due to a substance or known physiological condition (F52.-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026

Clinical classification (CCSR)

• MBD013 — Miscellaneous mental and behavioral disorders/conditions[CCSR]— AHRQ CCSR for ICD-10-CM Diagnoses (HCUP)

MS-DRG Grouper

• DRG 887 — OTHER MENTAL DISORDER DIAGNOSES[MS-DRG]: “OTHER MENTAL DISORDER DIAGNOSES (MDC 19)”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026

MDC crossing

• MDC 19 — Mental Diseases and Disorders[MDC crossing]: “Mental Diseases and Disorders — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs.”— CMS MS-DRG Definitions Manual · FY2026

Index entries

• Dysfunction, ejaculatory, premature[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
• Dysfunction, psychosexual, with, premature ejaculation[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
• Dysfunction, sexual (due to), male, ejaculatory, premature[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
• Dysfunction, sexual (due to), male, psychogenic, premature ejaculation[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
• Dysfunction, sexual (due to), premature ejaculation[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
• Ejaculation, premature[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
• Premature, ejaculation[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026

Nearest codes (13)

• F52 — Sexual dysfunction not due to a substance or known physiological condition[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• F52.0 — Hypoactive sexual desire disorder[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• F52.1 — Sexual aversion disorder[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• F52.2 — Sexual arousal disorders[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• F52.21 — Male erectile disorder[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• F52.22 — Female sexual arousal disorder[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• F52.3 — Orgasmic disorder[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• F52.31 — Female orgasmic disorder[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• and 5 more

Change history

• FY2016 — In the code set at ICD-10-CM adoption [Change history]— CMS release files (code change ledger) · icd10cm-fy2016

Sources for this page

Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.

Code, title, tabular notes and index terms Official source data

CMS/CDC ICD-10-CM FY2026 tabular list, index and tables, effective October 1, 2025 Release, file and checksum · Publisher’s page

Claim edits Official source data

CMS Definitions of Medicare Code Edits — v43.1 (April 2026) Release, file and checksum · Publisher’s page

Inpatient payment groups Official source data

CMS MS-DRG Definitions Manual (incl. Appendix B diagnosis index, Appendix C CC/MCC list, Appendix E procedure index) and IPPS Final Rule tables — v43 Release, file and checksum · Publisher’s page

Change history and date-of-service validity Official source data

CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page

Comparisons, relationships and the contextual map MedCoder structured relationship

Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears

Summary and FAQ answers MedCoder explanation

Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.

Labels on this page: Official source data · MedCoder structured relationship · MedCoder explanation. How to read the labels · All data sources and release dates

Nearest Codes in This Family

Official ICD-10-CM classifications closest to F52.4 in its code family, with their registry titles.

• F52.2 — Sexual arousal disorders
• F52.21 — Male erectile disorder
• F52.22 — Female sexual arousal disorder
• F52.3 — Orgasmic disorder
• F52.31 — Female orgasmic disorder
• F52.32 — Male orgasmic disorder
• F52.5 — Vaginismus not due to a substance or known physiological condition
• F52.6 — Dyspareunia not due to a substance or known physiological condition
• F52.8 — Other sexual dysfunction not due to a substance or known physiological condition
• F52.9 — Unspecified sexual dysfunction not due to a substance or known physiological condition

View all codes in the F52 family