H33.22 ICD-10-CM Code: Serous retinal detachment, left eye
Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.
Coding at a Glance
- Tabular directives
- 2 Excludes1
Inpatient Payment Groups (MS-DRG)
Potential MS-DRG participation — not a DRG assignment.
MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v43, Appendix B.
- MS-DRG 124 — OTHER DISORDERS OF THE EYE WITH MCC OR THROMBOLYTIC AGENT (MDC 02)
- MS-DRG 125 — OTHER DISORDERS OF THE EYE WITHOUT MCC (MDC 02)
A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.
Coding instructions
Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for H33.22 in the official ICD-10-CM tabular list, quoted as published.
Source: CMS/CDC — ICD-10-CM Tabular ListRelease: FY2026Effective: October 1, 2025
Notes without a marker are published on H33.22 itself; “inherited from” names the category or block whose note applies here.
Excludes1 — Not Coded Here
Conditions generally not reported together with this code (Excludes1) -- an error unless the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
- central serous chorioretinopathy (H35.71-) inherited from H33.2Compare H33.22 vs H35.71 →
- detachment of retinal pigment epithelium (H35.72-, H35.73-) inherited from H33Compare H33.22 vs H35.72 →
Coder workflow for H33.22
MedCoder structured workflow — derived from this code’s own official record
Before you code H33.22
- Laterality is coded in this family. Confirm the side documented — right, left, or bilateral — and select the matching code (this page’s code: left). The unspecified-side code applies only when the record states no side. Laterality is assigned from the documented side; where a bilateral code exists and both sides are documented, it is used instead of two unilateral codes (Guidelines I.B.13).
ReviewH33.21 · right, H33.23 · bilateral, H33.20 · unspecified
- Check the Excludes1 note: if the documentation supports a condition named there, do not simply proceed with H33.22. Excludes1 conditions are not reported together with this code unless the record shows they are unrelated (Guidelines I.A.12.a).
Choose the right path
- Does the documentation support a condition named in H33.22’s Excludes1 note?
Yes → Do not simply proceed: review the excluded code. Both are reported only when the record shows the two conditions are unrelated.
No → Continue. - Is the side documented?
Yes → Select the code for the documented side (or the bilateral code when both sides are documented and one exists).
No → Use the unspecified-side code only when the record states no side; a query is the alternative.ReviewH33.21 · right, H33.23 · bilateral, H33.20 · unspecified
Consider H33.22. Then confirm the code is valid for the date of service in the Verify section.
Documentation check
- The provider’s diagnostic statement
- Codes are assigned from the provider’s documented diagnosis, not from clinical criteria, test values or a medication list (Guidelines I.A.19).
- Laterality
- Right, left or bilateral as documented; unspecified only when the record states no side (Guidelines I.B.13).
Official instructions as workflow
Excludes1 — check before selecting H33.22(2 notes)
Coding workflow: If the documentation supports a condition named in this note, do not simply proceed with H33.22: the two are not reported together. The one exception is when the record shows the two conditions are unrelated to each other.
See the official tabular notes · Guidelines I.A.12.a
Coding decision scenarios
Pattern scenarios for this code’s structure — decision rules, not clinical cases
Documentation: Both the condition H33.22 describes and a condition named in its Excludes1 note are documented for the same encounter.
Coding question: Can both codes be reported?
Path: Review the Excludes1 note and the excluded code, and look for a provider statement on whether the two conditions are related.
Reason: Excludes1 means the two are not coded together; the exception is when the record shows the conditions are unrelated to each other (Guidelines I.A.12.a).
Documentation: The record documents the condition on one side only.
Coding question: Which code in this family applies?
Path: Select the sibling code for the documented side.
Reason: Laterality is assigned from the documented side; the unspecified-side code is for records that state no side (Guidelines I.B.13).
ReviewH33.21 · right, H33.23 · bilateral, H33.20 · unspecified
Every row is derived from this code’s own record — its title, tabular notes, 7th-character family and same-category siblings — with fixed MedCoder wording; nothing is inferred about a patient. The official notes and guideline text are in the sections each row links to, and they control.
Code Overview
MedCoder summary Summary composed by MedCoder from this code's official ICD-10-CM record. The tabular instructional notes themselves appear verbatim below.
Verify Before Coding
- CC as a secondary diagnosis (FY2026). Can raise the stay's MS-DRG severity tier.
From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.
Relationships & Classification
MedCoder structured relationships — computed from published CMS and AHRQ datasets
Other codes that name H33.22 or its code family, from the CMS ICD-10-CM tabular instructional notes. Tabular-note edges are stored at the code family level that carries each note.
Referenced by 2 Excludes1 notes: H33.0 — Retinal detachment with retinal break (via H33.2.-), H35.7 — Separation of retinal layers (via H33.2.-).
These codes’ tabular lists mark this diagnosis as mutually exclusive — not reported together unless the conditions are documented as unrelated.
Referenced by 1 Use Additional Code instruction: H44.2C — Degenerative myopia with retinal detachment (via H33.-).
These codes instruct coders to additionally report this code when it applies.
MS-DRG Grouper Relationships (FY2026)
Potential MS-DRG participation — not a DRG assignment.
FY2026 MS-DRG: CC — Complication or Comorbidity. Reported as a secondary diagnosis, this code raises the stay's MS-DRG severity tier — except when the principal diagnosis is one of 74 clinically related codes on its CMS exclusion list.
Named in the grouper logic of 2 MS-DRGs: DRG 124 (MDC 02), DRG 125 (MDC 02).
From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.
Clinical classification (AHRQ CCSR):EYE005 — Retinal and vitreous conditions (default).
Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.
Related Codes
Same clinical process (MS-DRG)
Acts as CC — raises the severity of other admissions. CMS groups these diagnoses into one MS-DRG principal-diagnosis exclusion process — a CC/MCC on this list never raises severity when the principal diagnosis is also on it.
H33.111 — Cyst of ora serrata, right eye, H33.112 — Cyst of ora serrata, left eye, H33.113 — Cyst of ora serrata, bilateral, H33.119 — Cyst of ora serrata, unspecified eye, H33.191 — Other retinoschisis and retinal cysts, right eye, H33.192 — Other retinoschisis and retinal cysts, left eye, H33.193 — Other retinoschisis and retinal cysts, bilateral, H33.199 — Other retinoschisis and retinal cysts, unspecified eye, H33.20 — Serous retinal detachment, unspecified eye, H33.21 — Serous retinal detachment, right eye, H33.23 — Serous retinal detachment, bilateral, H33.301 — Unspecified retinal break, right eye, H33.302 — Unspecified retinal break, left eye, H33.303 — Unspecified retinal break, bilateral, H33.309 — Unspecified retinal break, unspecified eye, H33.311 — Horseshoe tear of retina without detachment, right eye, H33.312 — Horseshoe tear of retina without detachment, left eye, H33.313 — Horseshoe tear of retina without detachment, bilateral, H33.319 — Horseshoe tear of retina without detachment, unspecified eye, H33.321 — Round hole, right eye, +53 more
Same condition, opposite side
Same category and title, differing only in which side of the body is affected.
H33.20 — Serous retinal detachment, unspecified eye (unspecified)Compare H33.22 vs H33.20 →, H33.21 — Serous retinal detachment, right eye (right)Compare H33.22 vs H33.21 →, H33.23 — Serous retinal detachment, bilateral (bilateral)Compare H33.22 vs H33.23 →
Same clinical category (CCSR)
AHRQ's Clinical Classifications Software groups these diagnoses under the same clinical category (Retinal and vitreous conditions).
Same Index main term, other category
The ICD-10-CM Index to Diseases and Injuries files this code under the main term “Detachment”; these codes share that main term but sit in a different category of the Tabular List.
H31.40 — Unspecified choroidal detachment (choroid), H31.41 — Hemorrhagic choroidal detachment (choroid, hemorrhagic), H31.42 — Serous choroidal detachment (choroid, serous), H43.81 — Vitreous degeneration (vitreous), N88.8 — Other specified noninflammatory disorders of cervix uteri (cervix, annular), O71.3 — Obstetric laceration of cervix (cervix, annular, complicating delivery)
Contextual Map
Every relationship of H33.22 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.
Run H33.22 with these 3 related codes in Claim Check
Hierarchy
- H00-H59 — Chapter 7: Diseases of the Eye and Adnexa (H00-H59) (H00-H59)[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- H30-H36 — Disorders of choroid and retina[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
Referenced by Excludes1 notes
- H33.0 — Retinal detachment with retinal break[Excludes1](via H33.2.-): “serous retinal detachment (without retinal break) (H33.2-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- H35.7 — Separation of retinal layers[Excludes1](via H33.2.-): “retinal detachment (serous) (H33.2-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
Referenced by Use Additional Code instructions
- H44.2C — Degenerative myopia with retinal detachment[Use Additional Code](via H33.-): “code to identify the retinal detachment (H33.-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
Clinical classification (CCSR)
- EYE005 — Retinal and vitreous conditions[CCSR]— AHRQ CCSR for ICD-10-CM Diagnoses (HCUP)
MS-DRG Grouper
- CC — Complication or Comorbidity [MS-DRG severity]: “As a secondary diagnosis this code can raise the stay's MS-DRG severity tier (CC).”— CMS MS-DRG Definitions Manual (Appendix C) · FY2026
- DRG 124 — OTHER DISORDERS OF THE EYE WITH MCC OR THROMBOLYTIC AGENT[MS-DRG]: “OTHER DISORDERS OF THE EYE WITH MCC OR THROMBOLYTIC AGENT (MDC 02)”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026
- DRG 125 — OTHER DISORDERS OF THE EYE WITHOUT MCC[MS-DRG]: “OTHER DISORDERS OF THE EYE WITHOUT MCC (MDC 02)”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026
MDC crossing
- MDC 02 — Diseases and Disorders of the Eye[MDC crossing]: “Diseases and Disorders of the Eye — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs. 1,200 same-MDC procedures group here; browse them on the MDC page.”— CMS MS-DRG Definitions Manual · FY2026
Nearest codes (40)
- H33 — Retinal detachments and breaks[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- H33.103 — Unspecified retinoschisis, bilateral[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- H33.109 — Unspecified retinoschisis, unspecified eye[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- H33.11 — Cyst of ora serrata[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- H33.111 — Cyst of ora serrata, right eye[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- H33.112 — Cyst of ora serrata, left eye[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- H33.113 — Cyst of ora serrata, bilateral[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- H33.119 — Cyst of ora serrata, unspecified eye[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- and 32 more
Change history
- FY2016 — In the code set at ICD-10-CM adoption [Change history]— CMS release files (code change ledger) · icd10cm-fy2016
Sources for this page
Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.
- Code, title, tabular notes and index terms Official source data
- CMS/CDC ICD-10-CM FY2026 tabular list, index and tables, effective October 1, 2025 Release, file and checksum · Publisher’s page
- Claim edits Official source data
- CMS Definitions of Medicare Code Edits — v43.1 (April 2026) Release, file and checksum · Publisher’s page
- Inpatient payment groups Official source data
- CMS MS-DRG Definitions Manual (incl. Appendix B diagnosis index, Appendix C CC/MCC list, Appendix E procedure index) and IPPS Final Rule tables — v43 Release, file and checksum · Publisher’s page
- Change history and date-of-service validity Official source data
- CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page
- Comparisons, relationships and the contextual map MedCoder structured relationship
- Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears
- Summary and FAQ answers MedCoder explanation
- Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.
Labels on this page: Official source data · MedCoder structured relationship · MedCoder explanation. How to read the labels · All data sources and release dates
Cite this page
Reference this page in a research guide, syllabus or article. The release is included because code content changes each year.
MedCoder.ai. "H33.22 — Serous retinal detachment, left eye." ICD-10-CM FY2026. https://medcoder.ai/icd10/code/h33.22-serous-retinal-detachment-left-eye
Change history
- FY2016 — October 1, 2015In the code set at ICD-10-CM adoptionSerous retinal detachment, left eye
No changes since FY2016 — additions, deletions, description changes and billable-status changes are tracked through FY2027 (effective October 1, 2026), and none are recorded for this code. Note changes are tracked from FY2027 only.
Nearest Codes in This Family
Official ICD-10-CM classifications closest to H33.22 in its code family, with their registry titles.
- H33.193 — Other retinoschisis and retinal cysts, bilateral
- H33.199 — Other retinoschisis and retinal cysts, unspecified eye
- H33.2 — Serous retinal detachment
- H33.20 — Serous retinal detachment, unspecified eye
- H33.21 — Serous retinal detachment, right eye
- H33.23 — Serous retinal detachment, bilateral
- H33.3 — Retinal breaks without detachment
- H33.30 — Unspecified retinal break
- H33.301 — Unspecified retinal break, right eye
- H33.302 — Unspecified retinal break, left eye