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N14.3 ICD-10-CM Code: Nephropathy induced by heavy metals

Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.

Coding at a Glance

Tabular directives
1 inclusion term · 1 Excludes1 · 1 use-additional code · 1 code-first instruction

Inpatient Payment Groups (MS-DRG)

Potential MS-DRG participation — not a DRG assignment.

MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v44, Appendix B.

  • MS-DRG 698 — OTHER KIDNEY AND URINARY TRACT DIAGNOSES WITH MCC (MDC 11)
  • MS-DRG 699 — OTHER KIDNEY AND URINARY TRACT DIAGNOSES WITH CC (MDC 11)
  • MS-DRG 700 — OTHER KIDNEY AND URINARY TRACT DIAGNOSES WITHOUT CC/MCC (MDC 11)

A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.

Coding instructions

Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for N14.3 in the official ICD-10-CM tabular list, quoted as published.

Source: CMS/CDC — ICD-10-CM Tabular ListRelease: FY2027Effective: October 1, 2026

Trace:FY2027 changesChange historyRelease, file and checksum

Notes without a marker are published on N14.3 itself; “inherited from” names the category or block whose note applies here.

Includes

Conditions the official ICD-10-CM tabular list includes under this code.

  • pyelonephritis

Source: inherited from N10-N16

Excludes1 — Not Coded Here

Conditions generally not reported together with this code (Excludes1) -- an error unless the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Source: inherited from N10-N16

Code First

Underlying conditions that must be sequenced before this code.

  • poisoning due to drug or toxin, if applicable (T36-T65 with fifth or sixth character 1-4)

Source: inherited from N14

Use Additional Code

Supplementary codes the tabular list directs you to add.

  • Use additional code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Source: inherited from N14

Coder workflow for N14.3

MedCoder structured workflow — derived from this code’s own official record

Before you code N14.3

  1. Check the Excludes1 note: if the documentation supports a condition named there, do not simply proceed with N14.3. Excludes1 conditions are not reported together with this code unless the record shows they are unrelated (Guidelines I.A.12.a).

    See the official tabular notes

Choose the right path

  1. Does the documentation support a condition named in N14.3’s Excludes1 note?
    Yes → Do not simply proceed: review the excluded code. Both are reported only when the record shows the two conditions are unrelated.
    No → Continue.

    ReviewN28.85

  2. Is the underlying (etiologic) condition the Code First note names documented?
    Yes → Sequence the underlying condition first, then N14.3.
    No → Continue; do not add an underlying condition the record does not document.

Consider N14.3. Then work the Use Additional Code note, and confirm the code is valid for the date of service in the Verify section.

Documentation check

The provider’s diagnostic statement
Codes are assigned from the provider’s documented diagnosis, not from clinical criteria, test values or a medication list (Guidelines I.A.19).
The underlying (etiologic) condition
Named in the Code First note; sequenced before this code when documented (Guidelines I.A.13).
The conditions the Use Additional Code note names
Reported with this code when documented; a conditional instruction (“if applicable”, “if known”) applies only when the record supports it.

Official instructions as workflow

  • Excludes1 — check before selecting N14.3(1 note)

    Coding workflow: If the documentation supports a condition named in this note, do not simply proceed with N14.3: the two are not reported together. The one exception is when the record shows the two conditions are unrelated to each other.

    CompareN28.85

    See the official tabular notes · Guidelines I.A.12.a

  • Code First — sequencing check(1 note)

    Coding workflow: Check whether the underlying or etiologic condition the note names is documented. When it is, sequence it before N14.3. Do not add an underlying condition the record does not document.

    See the official tabular notes · Guidelines I.A.13

  • Use Additional Code — after identifying N14.3(1 note)

    Coding workflow: Check whether the documentation supports the additional code(s) the note names, and report them with N14.3 when it does. Where the instruction is conditional (“if applicable”, “if known”), it applies only when the record documents the condition.

    See the official tabular notes · Guidelines I.A.13

Coding decision scenarios

Pattern scenarios for this code’s structure — decision rules, not clinical cases

Documentation: Both the condition N14.3 describes and a condition named in its Excludes1 note are documented for the same encounter.

Coding question: Can both codes be reported?

Path: Review the Excludes1 note and the excluded code, and look for a provider statement on whether the two conditions are related.

Reason: Excludes1 means the two are not coded together; the exception is when the record shows the conditions are unrelated to each other (Guidelines I.A.12.a).

ReviewN28.85

Documentation: The underlying condition the Code First note names is documented alongside this condition.

Coding question: How are the two sequenced?

Path: Review the Code First note.

Reason: The underlying condition is sequenced first and the manifestation follows (Guidelines I.A.13).

Documentation: A condition the Use Additional Code note names is documented.

Coding question: Is a second code reported with N14.3?

Path: Review the Use Additional Code note and the code it names.

Reason: The additional code is reported when the record documents the condition; a conditional instruction applies only when its condition is met (Guidelines I.A.13).

Every row is derived from this code’s own record — its title, tabular notes, 7th-character family and same-category siblings — with fixed MedCoder wording; nothing is inferred about a patient. The official notes and guideline text are in the sections each row links to, and they control.

Don’t confuse N14.3 with…

MedCoder analysis — pairs from this code’s official notes, distinctions written by MedCoder

The codes most likely to be picked instead of N14.3 — named in its own official notes, or sharing its laterality or encounter family — with what separates them and which documentation moves the case. Each links to the full comparison.

  • N28.85— Excludes1 conflict (Excludes1 — generally not reported together)

    Not coded here — the tabular list excludes this pair for the same encounter.

    Not reported together with this code, except where the two conditions are documented as unrelated.

    What moves you there: Documentation of pyeloureteritis cystica moves the case to N28.85; the two are not reported together unless documented as unrelated.

    Full comparison: N14.3 vs N28.85 →

  • N14.2— Specificity relationship (Review)

    Overlapping diagnoses in the same category.

    Overlapping codes in the same category — the documentation decides which is the more specific fit.

    What moves you there: A record that documents no more than “Nephropathy induced by unspecified drug, medicament or biological substance” takes N14.2; specificity in the record moves it back here.

    Full comparison: N14.3 vs N14.2 →

Relationships are read from this code's own official notes, its laterality siblings and its encounter family; the wording of each distinction is MedCoder editorial, and the documentation named in each “what moves you there” line is the official note phrase or sibling title itself. Source: CMS ICD-10-CM tabular instructional notes; ICD-10-CM Official Guidelines, Section I.A.12.a.

Code Overview

Nephropathy induced by heavy metals is a billable ICD-10-CM diagnosis code (N14.3).

MedCoder summary Summary composed by MedCoder from this code's official ICD-10-CM record. The tabular instructional notes themselves appear verbatim below.

Indexed Clinical Terms (6)

Official source data — entries quoted as published, in the Index’s own lookup phrasing

Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code. These are alphabetic-index entries shown as the Index writes them — lookup phrasing, not necessarily the wording of a final diagnosis.

Decision Points

The directives on this code's own record, as a pre-claim checklist.

  1. Sequencing: 1 Code First instruction — the underlying condition is sequenced before this code when present. See the Code First notes
  2. 1 Use Additional Code instruction — report the named additional code(s) when the documentation supports them. See the Use Additional Code notes
  3. 1 Excludes1 entry — codes named there are generally not reported together with this code (Guidelines I.A.12.a). See the Excludes1 notes

Checklist rows are derived from this code's own official directives; the wording of each check is MedCoder editorial. The official notes themselves are in the sections each row links to.

Verify Before Coding

  • No Medicare Code Editor or MS-DRG Definitions Manual restrictions apply to this code.

From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.

Relationships & Classification

MedCoder structured relationships — computed from published CMS and AHRQ datasets

Other codes that name N14.3 or its code family, from the CMS ICD-10-CM tabular instructional notes. Tabular-note edges are stored at the code family level that carries each note.

Referenced by 4 Excludes2 notes: N17 — Acute kidney failure (via N14.-), N17-N19 — Acute kidney failure and chronic kidney disease (N17-N19) (via N14.-), N18 — Chronic kidney disease (CKD) (via N14.-), N19 — Unspecified kidney failure (via N14.-).

These codes’ tabular lists name this diagnosis as distinct — both may be reported when both are documented.

MS-DRG Grouper Relationships (FY2027)

Potential MS-DRG participation — not a DRG assignment.

FY2027 MS-DRG: not on the CMS CC/MCC list — as a secondary diagnosis this code does not change MS-DRG severity for that release.

Named in the grouper logic of 3 MS-DRGs: DRG 698 (MDC 11), DRG 699 (MDC 11), DRG 700 (MDC 11).

From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.

Clinical classification (AHRQ CCSR):INJ030 — Drug induced or toxic related condition (default); GEN001 — Nephritis; nephrosis; renal sclerosis.

Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.

Related Codes

Same clinical category (CCSR)

AHRQ's Clinical Classifications Software groups these diagnoses under the same clinical categories (Drug induced or toxic related condition, Nephritis; nephrosis; renal sclerosis).

N07.8 — Hereditary nephropathy, not elsewhere classified with other morphologic lesions, N07.9 — Hereditary nephropathy, not elsewhere classified with unspecified morphologic lesions, N07.A — Hereditary nephropathy, not elsewhere classified with C3 glomerulonephritis, N07.B — Hereditary nephropathy, not elsewhere classified with APOL1-mediated kidney disease [AMKD], N08 — Glomerular disorders in diseases classified elsewhere, N14.0 — Analgesic nephropathy, N14.1 — Nephropathy induced by other drugs, medicaments and biological substances, N14.11 — Contrast-induced nephropathy, N14.19 — Nephropathy induced by other drugs, medicaments and biological substances, N14.2 — Nephropathy induced by unspecified drug, medicament or biological substance, N14.4 — Toxic nephropathy, not elsewhere classified, N15.0 — Balkan nephropathy, N15.8 — Other specified renal tubulo-interstitial diseases, N15.9 — Renal tubulo-interstitial disease, unspecified, N16 — Renal tubulo-interstitial disorders in diseases classified elsewhere, N26.9 — Renal sclerosis, unspecified, N46.021 — Azoospermia due to drug therapy, N46.121 — Oligospermia due to drug therapy, N48.33 — Priapism, drug-induced, N52.2 — Drug-induced erectile dysfunction, +353 more

Same Index main term, other category

The ICD-10-CM Index to Diseases and Injuries files this code under the main terms “Nephropathy”, “Nephritis, nephritic”; these codes share that main term but sit in a different category of the Tabular List.

N07.9 — Hereditary nephropathy, not elsewhere classified with unspecified morphologic lesions (hereditary NEC), N07.A — Hereditary nephropathy, not elsewhere classified with C3 glomerulonephritis (hereditary NEC, with, C3, glomerulopathy), N07.B — Hereditary nephropathy, not elsewhere classified with APOL1-mediated kidney disease [AMKD] (hereditary NEC, with, APOL1-mediated kidney disease), N10 — Acute pyelonephritis (tubulo-interstitial, acute), N11.0 — Nonobstructive reflux-associated chronic pyelonephritis (tubulo-interstitial, chronic, nonobstructive, reflux-associated), N11.1 — Chronic obstructive pyelonephritis (tubulo-interstitial, chronic, obstructive), N11.8 — Other chronic tubulo-interstitial nephritis (tubulo-interstitial, chronic, specified NEC), N11.9 — Chronic tubulo-interstitial nephritis, unspecified (tubulo-interstitial, chronic), N12 — Tubulo-interstitial nephritis, not specified as acute or chronic (tubulo-interstitial), N13.8 — Other obstructive and reflux uropathy (obstructive), N15.0 — Balkan nephropathy (Balkan), N17.0 — Acute kidney failure with tubular necrosis (vasomotor), N17.2 — Acute kidney failure with medullary necrosis (phenacetin), N25.0 — Renal osteodystrophy (phosphate-losing), N25.89 — Other disorders resulting from impaired renal tubular function (hypokalemic), N26.9 — Renal sclerosis, unspecified (cirrhotic), N28.89 — Other specified disorders of kidney and ureter (salt losing or wasting NEC), N28.9 — Disorder of kidney and ureter, unspecified, O26.83 — Pregnancy related renal disease (pregnancy-related), Q61.19 — Other polycystic kidney, infantile type (polycystic, childhood type NEC), +92 more

Lab tests where this diagnosis supports Medicare coverage (NCD)

Medicare's National Coverage Determination (NCD) program lists this diagnosis as medical justification for these lab tests.

Gamma-glutamyl Transferase (GGT) Test

Contextual Map

Every relationship of N14.3 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Run N14.3 with these 4 related codes in Claim Check

Hierarchy

Referenced by Excludes2 notes

  • N17 — Acute kidney failure[Excludes2](via N14.-): “drug- and heavy-metal-induced tubulo-interstitial and tubular conditions (N14.-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2027
  • N17-N19 — Acute kidney failure and chronic kidney disease (N17-N19)[Excludes2](via N14.-): “drug- and heavy-metal-induced tubulo-interstitial and tubular conditions (N14.-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2027
  • N18 — Chronic kidney disease (CKD)[Excludes2](via N14.-): “drug- and heavy-metal-induced tubulo-interstitial and tubular conditions (N14.-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2027
  • N19 — Unspecified kidney failure[Excludes2](via N14.-): “drug- and heavy-metal-induced tubulo-interstitial and tubular conditions (N14.-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2027

Clinical classification (CCSR)

MS-DRG Grouper

MDC crossing

  • MDC 11 — Diseases and Disorders of the Kidney and Urinary Tract[MDC crossing]: “Diseases and Disorders of the Kidney and Urinary Tract — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs. 3,578 same-MDC procedures group here; browse them on the MDC page.”— CMS MS-DRG Definitions Manual · FY2027

Index entries

  • Nephritis, nephritic (albuminuric) (azotemic) (congenital) (disseminated) (epithelial) (familial) (focal) (granulomatous) (hemorrhagic) (infantile) (nonsuppurative, excretory) (uremic), lead[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2027
  • Nephritis, nephritic (albuminuric) (azotemic) (congenital) (disseminated) (epithelial) (familial) (focal) (granulomatous) (hemorrhagic) (infantile) (nonsuppurative, excretory) (uremic), saturnine[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2027
  • Nephropathy, heavy metal-induced[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2027
  • Nephropathy, lead[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2027
  • Nephropathy, saturnine[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2027
  • Nephropathy, toxic NEC, due to, heavy metals[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2027

Nearest codes

Change history

  • FY2016 — In the code set at ICD-10-CM adoption [Change history]— CMS release files (code change ledger) · icd10cm-fy2016

Sources for this page

Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.

Code, title, tabular notes and index terms Official source data
CMS/CDC ICD-10-CM FY2027 tabular list, index and tables, effective October 1, 2026 Release, file and checksum · Publisher’s page
Claim edits Official source data
CMS Definitions of Medicare Code Edits — v44.0 (October 2026) Release, file and checksum · Publisher’s page
Inpatient payment groups Official source data
CMS MS-DRG Definitions Manual (incl. Appendix B diagnosis index, Appendix C CC/MCC list, Appendix E procedure index) and IPPS Final Rule tables — v44 Release, file and checksum · Publisher’s page
Change history and date-of-service validity Official source data
CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page
Comparisons, relationships and the contextual map MedCoder structured relationship
Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears
Summary and FAQ answers MedCoder explanation
Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.

Labels on this page: Official source data · MedCoder structured relationship · MedCoder explanation. How to read the labels · All data sources and release dates

Cite this page

Reference this page in a research guide, syllabus or article. The release is included because code content changes each year.

MedCoder.ai. "N14.3 — Nephropathy induced by heavy metals." ICD-10-CM FY2027. https://medcoder.ai/icd10/code/n14.3-nephropathy-induced-by-heavy-metals

Change history

  • FY2016 — October 1, 2015
    In the code set at ICD-10-CM adoption
    Nephropathy induced by heavy metals

No changes since FY2016 — additions, deletions, description changes and billable-status changes are tracked through FY2027, and none are recorded for this code. Note changes are tracked from FY2027 only.

Nearest Codes in This Family

Official ICD-10-CM classifications closest to N14.3 in its code family, with their registry titles.

View all codes in the N14 family