N64.52 ICD-10-CM Code: Nipple discharge
Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.
Coding at a Glance
- Tabular directives
- 2 Excludes1 · 2 Excludes2
Inpatient Payment Groups (MS-DRG)
Potential MS-DRG participation — not a DRG assignment.
MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v43, Appendix B.
- MS-DRG 600 — NON-MALIGNANT BREAST DISORDERS WITH CC/MCC (MDC 09)
- MS-DRG 601 — NON-MALIGNANT BREAST DISORDERS WITHOUT CC/MCC (MDC 09)
A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.
Coding instructions
Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for N64.52 in the official ICD-10-CM tabular list, quoted as published.
Source: CMS/CDC — ICD-10-CM Tabular ListRelease: FY2026Effective: October 1, 2025
Notes without a marker are published on N64.52 itself; “inherited from” names the category or block whose note applies here.
Excludes1 — Not Coded Here
Conditions generally not reported together with this code (Excludes1) -- an error unless the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
- abnormal findings in nipple discharge (R89.-) Compare N64.52 vs R89 →
- disorders of breast associated with childbirth (O91-O92) inherited from N60-N65Compare N64.52 vs O91 →
Excludes2 — Not Included Here
Conditions not covered by this code, but which may be reported alongside it when both are present.
- abnormal findings on diagnostic imaging of breast (R92.-) inherited from N64.5Compare N64.52 vs R92 →
- mechanical complication of breast prosthesis and implant (T85.4-) inherited from N64Compare N64.52 vs T85.4 →
Coder workflow for N64.52
MedCoder structured workflow — derived from this code’s own official record
Before you code N64.52
- Check the Excludes1 note: if the documentation supports a condition named there, do not simply proceed with N64.52. Excludes1 conditions are not reported together with this code unless the record shows they are unrelated (Guidelines I.A.12.a).
Choose the right path
- Does the documentation support a condition named in N64.52’s Excludes1 note?
Yes → Do not simply proceed: review the excluded code. Both are reported only when the record shows the two conditions are unrelated.
No → Continue.ReviewR89
Consider N64.52. Then confirm the code is valid for the date of service in the Verify section.
Documentation check
- The provider’s diagnostic statement
- Codes are assigned from the provider’s documented diagnosis, not from clinical criteria, test values or a medication list (Guidelines I.A.19).
Official instructions as workflow
Excludes1 — check before selecting N64.52(2 notes)
Coding workflow: If the documentation supports a condition named in this note, do not simply proceed with N64.52: the two are not reported together. The one exception is when the record shows the two conditions are unrelated to each other.
CompareR89
See the official tabular notes · Guidelines I.A.12.a
Excludes2 — not part of N64.52(2 notes)
Coding workflow: The conditions named in this note are not included in N64.52. When the record documents both, both may be reported; the note is a boundary, not a prohibition.
See the official tabular notes · Guidelines I.A.12.b
Coding decision scenarios
Pattern scenarios for this code’s structure — decision rules, not clinical cases
Documentation: Both the condition N64.52 describes and a condition named in its Excludes1 note are documented for the same encounter.
Coding question: Can both codes be reported?
Path: Review the Excludes1 note and the excluded code, and look for a provider statement on whether the two conditions are related.
Reason: Excludes1 means the two are not coded together; the exception is when the record shows the conditions are unrelated to each other (Guidelines I.A.12.a).
ReviewR89
Every row is derived from this code’s own record — its title, tabular notes, 7th-character family and same-category siblings — with fixed MedCoder wording; nothing is inferred about a patient. The official notes and guideline text are in the sections each row links to, and they control.
Code Overview
MedCoder summary Summary composed by MedCoder from this code's official ICD-10-CM record. The tabular instructional notes themselves appear verbatim below.
Indexed Clinical Terms (2)
Official source data — entries quoted as published, in the Index’s own lookup phrasing
Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code. These are alphabetic-index entries shown as the Index writes them — lookup phrasing, not necessarily the wording of a final diagnosis.
Verify Before Coding
- No Medicare Code Editor or MS-DRG Definitions Manual restrictions apply to this code.
From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.
Relationships & Classification
MedCoder structured relationships — computed from published CMS and AHRQ datasets
Other codes that name N64.52 or its code family, from the CMS ICD-10-CM tabular instructional notes. Tabular-note edges are stored at the code family level that carries each note.
Referenced by 5 Excludes2 notes: R20 — Disturbances of skin sensation, R20-R23 — Symptoms and signs involving the skin and subcutaneous tissue (R20-R23), R21 — Rash and other nonspecific skin eruption, R22 — Localized swelling, mass and lump of skin and subcutaneous tissue, R23 — Other skin changes.
These codes’ tabular lists name this diagnosis as distinct — both may be reported when both are documented.
MS-DRG Grouper Relationships (FY2026)
Potential MS-DRG participation — not a DRG assignment.
FY2026 MS-DRG: not on the CMS CC/MCC list — as a secondary diagnosis this code does not change MS-DRG severity for that release.
Named in the grouper logic of 2 MS-DRGs: DRG 600 (MDC 09), DRG 601 (MDC 09).
From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.
Clinical classification (AHRQ CCSR):GEN017 — Nonmalignant breast conditions (default).
Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.
Related Codes
Same clinical category (CCSR)
AHRQ's Clinical Classifications Software groups these diagnoses under the same clinical category (Nonmalignant breast conditions).
N63.31 — Unspecified lump in axillary tail of the right breast, N63.32 — Unspecified lump in axillary tail of the left breast, N63.41 — Unspecified lump in right breast, subareolar, N63.42 — Unspecified lump in left breast, subareolar, N64.0 — Fissure and fistula of nipple, N64.1 — Fat necrosis of breast, N64.2 — Atrophy of breast, N64.3 — Galactorrhea not associated with childbirth, N64.4 — Mastodynia, N64.51 — Induration of breast, N64.53 — Retraction of nipple, N64.59 — Other signs and symptoms in breast, N64.81 — Ptosis of breast, N64.82 — Hypoplasia of breast, N64.89 — Other specified disorders of breast, N64.9 — Disorder of breast, unspecified, N65.0 — Deformity of reconstructed breast, N65.1 — Disproportion of reconstructed breast, O91.011 — Infection of nipple associated with pregnancy, first trimester, O91.012 — Infection of nipple associated with pregnancy, second trimester, +65 more
Same Index main term, other category
The ICD-10-CM Index to Diseases and Injuries files this code under the main term “Discharge”; these codes share that main term but sit in a different category of the Tabular List.
N89.8 — Other specified noninflammatory disorders of vagina (vaginal), R09.82 — Postnasal drip (postnasal), R35.89 — Other polyuria (excessive urine), R36.0 — Urethral discharge without blood (urethral, without blood), R36.1 — Hematospermia (urethral, hematospermia), R36.9 — Urethral discharge, unspecified (penile), Z65.2 — Problems related to release from prison (prison, anxiety concerning)
Contextual Map
Every relationship of N64.52 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.
Run N64.52 with these 6 related codes in Claim Check
Hierarchy
- N00-N99 — Chapter 14: Diseases of the Genitourinary System (N00-N99) (N00-N99)[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- N60-N65 — Disorders of breast[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
Excludes1
- R89 — Abnormal findings in specimens from other organs, systems and tissues[Excludes1]: “abnormal findings in nipple discharge (R89.-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
Referenced by Excludes2 notes
- R20 — Disturbances of skin sensation[Excludes2]: “symptoms relating to breast (N64.4-N64.5)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- R20-R23 — Symptoms and signs involving the skin and subcutaneous tissue (R20-R23)[Excludes2]: “symptoms relating to breast (N64.4-N64.5)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- R21 — Rash and other nonspecific skin eruption[Excludes2]: “symptoms relating to breast (N64.4-N64.5)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- R22 — Localized swelling, mass and lump of skin and subcutaneous tissue[Excludes2]: “symptoms relating to breast (N64.4-N64.5)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- R23 — Other skin changes[Excludes2]: “symptoms relating to breast (N64.4-N64.5)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
Clinical classification (CCSR)
- GEN017 — Nonmalignant breast conditions[CCSR]— AHRQ CCSR for ICD-10-CM Diagnoses (HCUP)
MS-DRG Grouper
- DRG 600 — NON-MALIGNANT BREAST DISORDERS WITH CC/MCC[MS-DRG]: “NON-MALIGNANT BREAST DISORDERS WITH CC/MCC (MDC 09)”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026
- DRG 601 — NON-MALIGNANT BREAST DISORDERS WITHOUT CC/MCC[MS-DRG]: “NON-MALIGNANT BREAST DISORDERS WITHOUT CC/MCC (MDC 09)”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026
MDC crossing
- MDC 09 — Diseases and Disorders of the Skin, Subcutaneous Tissue and Breast[MDC crossing]: “Diseases and Disorders of the Skin, Subcutaneous Tissue and Breast — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs. 7,376 same-MDC procedures group here; browse them on the MDC page.”— CMS MS-DRG Definitions Manual · FY2026
Index entries
- Discharge (from), breast (female) (male)[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
- Discharge (from), nipple[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
Nearest codes (15)
- N64 — Other disorders of breast[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- N64.0 — Fissure and fistula of nipple[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- N64.1 — Fat necrosis of breast[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- N64.2 — Atrophy of breast[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- N64.3 — Galactorrhea not associated with childbirth[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- N64.4 — Mastodynia[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- N64.5 — Other signs and symptoms in breast[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- N64.51 — Induration of breast[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- and 7 more
Change history
- FY2016 — In the code set at ICD-10-CM adoption [Change history]— CMS release files (code change ledger) · icd10cm-fy2016
Sources for this page
Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.
- Code, title, tabular notes and index terms Official source data
- CMS/CDC ICD-10-CM FY2026 tabular list, index and tables, effective October 1, 2025 Release, file and checksum · Publisher’s page
- Claim edits Official source data
- CMS Definitions of Medicare Code Edits — v43.1 (April 2026) Release, file and checksum · Publisher’s page
- Inpatient payment groups Official source data
- CMS MS-DRG Definitions Manual (incl. Appendix B diagnosis index, Appendix C CC/MCC list, Appendix E procedure index) and IPPS Final Rule tables — v43 Release, file and checksum · Publisher’s page
- Change history and date-of-service validity Official source data
- CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page
- Comparisons, relationships and the contextual map MedCoder structured relationship
- Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears
- Summary and FAQ answers MedCoder explanation
- Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.
Labels on this page: Official source data · MedCoder structured relationship · MedCoder explanation. How to read the labels · All data sources and release dates
Cite this page
Reference this page in a research guide, syllabus or article. The release is included because code content changes each year.
MedCoder.ai. "N64.52 — Nipple discharge." ICD-10-CM FY2026. https://medcoder.ai/icd10/code/n64.52-nipple-discharge
Change history
- FY2016 — October 1, 2015In the code set at ICD-10-CM adoptionNipple discharge
No changes since FY2016 — additions, deletions, description changes and billable-status changes are tracked through FY2027 (effective October 1, 2026), and none are recorded for this code. Note changes are tracked from FY2027 only.
Nearest Codes in This Family
Official ICD-10-CM classifications closest to N64.52 in its code family, with their registry titles.
- N64.2 — Atrophy of breast
- N64.3 — Galactorrhea not associated with childbirth
- N64.4 — Mastodynia
- N64.5 — Other signs and symptoms in breast
- N64.51 — Induration of breast
- N64.53 — Retraction of nipple
- N64.59 — Other signs and symptoms in breast
- N64.8 — Other specified disorders of breast
- N64.81 — Ptosis of breast
- N64.82 — Hypoplasia of breast