O99.825 ICD-10-CM Code: Streptococcus B carrier state complicating the puerperium

Coding instructions

Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for O99.825 in the official ICD-10-CM tabular list, quoted as published.

Source: CMS/CDC — ICD-10-CM Tabular ListRelease: FY2026Effective: October 1, 2025

Notes without a marker are published on O99.825 itself; “inherited from” names the category or block whose note applies here.

Coder workflow for O99.825

MedCoder structured workflow — derived from this code’s own official record

Before you code O99.825

1. Confirm the condition is documented as complicating the pregnancy, childbirth, or the puerperium, and check the trimester where the code carries one and the fetus character where the category requires it. Chapter 15 codes belong on the maternal record only and take sequencing priority over codes from other chapters. It is the provider’s responsibility to state that a condition is not affecting the pregnancy; the trimester is assigned from the documentation (Guidelines I.C.15.a, I.C.15.a.1, I.C.15.a.3).

   Guide: How to choose an ICD-10-CM code →

2. Check the Excludes1 note: if the documentation supports a condition named there, do not simply proceed with O99.825. Excludes1 conditions are not reported together with this code unless the record shows they are unrelated (Guidelines I.A.12.a).

   See the official tabular notes

Choose the right path

1. Does the documentation support a condition named in O99.825’s Excludes1 note?
   Yes → Do not simply proceed: review the excluded code. Both are reported only when the record shows the two conditions are unrelated.
   No → Continue.

   ReviewZ22.330

Consider O99.825. Then work the Use Additional Code note, and confirm the code is valid for the date of service in the Verify section.

Documentation check

The provider’s diagnostic statement

Codes are assigned from the provider’s documented diagnosis, not from clinical criteria, test values or a medication list (Guidelines I.A.19).

Trimester

Assigned from the documented trimester at the encounter, or the trimester in which the condition developed for inpatient stays (Guidelines I.C.15.a.3).

The conditions the Use Additional Code note names

Reported with this code when documented; a conditional instruction (“if applicable”, “if known”) applies only when the record supports it.

Official instructions as workflow

• Excludes1 — check before selecting O99.825(1 note)

  Coding workflow: If the documentation supports a condition named in this note, do not simply proceed with O99.825: the two are not reported together. The one exception is when the record shows the two conditions are unrelated to each other.

  CompareZ22.330

  See the official tabular notes · Guidelines I.A.12.a

• Excludes2 — not part of O99.825(7 notes)

  Coding workflow: The conditions named in this note are not included in O99.825. When the record documents both, both may be reported; the note is a boundary, not a prohibition.

  CompareO23, O9A.1, O34, O90.49, O9A.2

  See the official tabular notes · Guidelines I.A.12.b

• Use Additional Code — after identifying O99.825(2 notes)

  Coding workflow: Check whether the documentation supports the additional code(s) the note names, and report them with O99.825 when it does. Where the instruction is conditional (“if applicable”, “if known”), it applies only when the record documents the condition.

  See the official tabular notes · Guidelines I.A.13

Coding decision scenarios

Pattern scenarios for this code’s structure — decision rules, not clinical cases

Every row is derived from this code’s own record — its title, tabular notes, 7th-character family and same-category siblings — with fixed MedCoder wording; nothing is inferred about a patient. The official notes and guideline text are in the sections each row links to, and they control.

Indexed Clinical Terms (1)

Official source data — entries quoted as published, in the Index’s own lookup phrasing

Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code. These are alphabetic-index entries shown as the Index writes them — lookup phrasing, not necessarily the wording of a final diagnosis.

• Puerperal, puerperium (complicated by, complications), infection, maternal, streptococcus group Bcarrier state (GBS)

Don’t confuse O99.825 with…

MedCoder analysis — pairs from this code’s official notes, distinctions written by MedCoder

The codes most likely to be picked instead of O99.825 — named in its own official notes, or sharing its laterality or encounter family — with what separates them and which documentation moves the case. Each links to the full comparison.

• Z22.330— Excludes1 conflict (Excludes1 — generally not reported together)

  Not coded here — the tabular list excludes this pair for the same encounter.

  Not reported together with this code, except where the two conditions are documented as unrelated.

  What moves you there: Documentation of Carrier of streptococcus group B (GBS) in a nonpregnant woman moves the case to Z22.330; the two are not reported together unless documented as unrelated.

  Full comparison: O99.825 vs Z22.330 →

• O23— Excludes2 relationship (Informational)

  Distinct conditions — both may be reported.

  A distinct condition — both may be reported when both are documented.

  What moves you there: Documentation of genitourinary infections in pregnancy adds O23; it is not part of this code and both may be reported when both are documented.

  Full comparison: O99.825 vs O23 →

• O86.1— Excludes2 relationship (Informational)

  Distinct conditions — both may be reported.

  A distinct condition — both may be reported when both are documented.

  What moves you there: Documentation of infection of genitourinary tract following delivery adds O86.1; it is not part of this code and both may be reported when both are documented.

  Full comparison: O99.825 vs O86.1 →

• O86.4— Excludes2 relationship (Informational)

  Distinct conditions — both may be reported.

  A distinct condition — both may be reported when both are documented.

  What moves you there: Documentation of infection of genitourinary tract following delivery adds O86.4; it is not part of this code and both may be reported when both are documented.

  Full comparison: O99.825 vs O86.4 →

• O9A.1— Excludes2 relationship (Informational)

  Distinct conditions — both may be reported.

  A distinct condition — both may be reported when both are documented.

  What moves you there: Documentation of malignant neoplasm complicating pregnancy, childbirth and the puerperium adds O9A.1; it is not part of this code and both may be reported when both are documented.

  Full comparison: O99.825 vs O9A.1 →

• O34— Excludes2 relationship (Informational)

  Distinct conditions — both may be reported.

  A distinct condition — both may be reported when both are documented.

  What moves you there: Documentation of maternal care for known or suspected abnormality of maternal pelvic organs adds O34; it is not part of this code and both may be reported when both are documented.

  Full comparison: O99.825 vs O34 →

Relationships are read from this code's own official notes, its laterality siblings and its encounter family; the wording of each distinction is MedCoder editorial, and the documentation named in each “what moves you there” line is the official note phrase or sibling title itself. Source: CMS ICD-10-CM tabular instructional notes; ICD-10-CM Official Guidelines, Section I.A.12.a.

Decision Points

The directives on this code's own record, as a pre-claim checklist.

1. 2 Use Additional Code instructions — report the named additional code(s) when the documentation supports them. See the Use Additional Code notes
2. 1 Excludes1 entry — codes named there are generally not reported together with this code (Guidelines I.A.12.a). See the Excludes1 notes
3. 7 Excludes2 entries — those conditions are not part of this code and may be reported additionally when documented. See the Excludes2 notes

Checklist rows are derived from this code's own official directives; the wording of each check is MedCoder editorial. The official notes themselves are in the sections each row links to.

Verify Before Coding

• Principal-diagnosis restriction. The Medicare Code Editor lists this code as unacceptable as a principal diagnosis: it describes a circumstance influencing health status rather than a current illness or injury being treated. It is valid as a secondary diagnosis.
• Age-restricted: the Medicare Code Editor lists this as a maternity (age 9-64) diagnosis; other ages are presumed incorrect.

From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.

Relationships & Classification

MedCoder structured relationships — computed from published CMS and AHRQ datasets

Other codes that name O99.825 or its code family, from the CMS ICD-10-CM tabular instructional notes. Tabular-note edges are stored at the code family level that carries each note.

Referenced by 1 Excludes1 note: Z22.330 — Carrier of Group B streptococcus (via O99.82.-).

These codes’ tabular lists mark this diagnosis as mutually exclusive — not reported together unless the conditions are documented as unrelated.

Referenced by 11 Excludes2 notes: O20 — Hemorrhage in early pregnancy (via O99.-), O20-O29 — Other maternal disorders predominantly related to pregnancy (O20-O29) (via O99.-), O21 — Excessive vomiting in pregnancy (via O99.-), O22 — Venous complications and hemorrhoids in pregnancy (via O99.-), O23 — Infections of genitourinary tract in pregnancy (via O99.-), O24 — Diabetes mellitus in pregnancy, childbirth, and the puerperium (via O99.-), O25 — Malnutrition in pregnancy, childbirth and the puerperium (via O99.-), O26 — Maternal care for other conditions predominantly related to pregnancy (via O99.-), O28 — Abnormal findings on antenatal screening of mother (via O99.-), O29 — Complications of anesthesia during pregnancy (via O99.-), O98 — Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium (via O99.82.-).

These codes’ tabular lists name this diagnosis as distinct — both may be reported when both are documented.

MS-DRG Grouper Relationships (FY2026)

Potential MS-DRG participation — not a DRG assignment.

FY2026 MS-DRG: not on the CMS CC/MCC list — as a secondary diagnosis this code does not change MS-DRG severity for that release.

Named in the grouper logic of 2 MS-DRGs: DRG 769 (MDC 14), DRG 776 (MDC 14).

From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.

Clinical classification (AHRQ CCSR):FAC024 — Carrier status; PRG027 — Complications specified during the puerperium (default).

Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.

Related Codes

Principal diagnosis restriction (Medicare Code Editor)

Not acceptable as a principal diagnosis on an inpatient claim.

Same clinical category (CCSR)

AHRQ's Clinical Classifications Software groups these diagnoses under the same clinical categories (Carrier status, Complications specified during the puerperium).

O99.335 — Smoking (tobacco) complicating the puerperium, O99.345 — Other mental disorders complicating the puerperium, O99.355 — Diseases of the nervous system complicating the puerperium, O99.43 — Diseases of the circulatory system complicating the puerperium, O99.53 — Diseases of the respiratory system complicating the puerperium, O99.63 — Diseases of the digestive system complicating the puerperium, O99.73 — Diseases of the skin and subcutaneous tissue complicating the puerperium, O99.815 — Abnormal glucose complicating the puerperium, O99.820 — Streptococcus B carrier state complicating pregnancy, O99.824 — Streptococcus B carrier state complicating childbirth, O99.830 — Other infection carrier state complicating pregnancy, O99.834 — Other infection carrier state complicating childbirth, O99.835 — Other infection carrier state complicating the puerperium, O99.845 — Bariatric surgery status complicating the puerperium, O99.893 — Other specified diseases and conditions complicating puerperium, O9A.13 — Malignant neoplasm complicating the puerperium, O9A.23 — Injury, poisoning and certain other consequences of external causes complicating the puerperium, O9A.33 — Physical abuse complicating the puerperium, O9A.43 — Sexual abuse complicating the puerperium, O9A.53 — Psychological abuse complicating the puerperium, +137 more

Same Index main term, other category

The ICD-10-CM Index to Diseases and Injuries files this code under the main terms “Puerperal, puerperium”, “Carrierof”; these codes share that main term but sit in a different category of the Tabular List.

O98.03 — Tuberculosis complicating the puerperium (infection, maternal, tuberculosis), O98.13 — Syphilis complicating the puerperium (infection, maternal, syphilis), O98.23 — Gonorrhea complicating the puerperium (gonorrhea), O98.33 — Other infections with a predominantly sexual mode of transmission complicating the puerperium (infection, maternal, sexually transmitted NEC), O98.43 — Viral hepatitis complicating the puerperium (infection, maternal, viral hepatitis), O98.53 — Other viral diseases complicating the puerperium (infection, maternal, viral NEC), O98.63 — Protozoal diseases complicating the puerperium (infection, maternal, protozoal), O98.73 — Human immunodeficiency virus [HIV] disease complicating the puerperium (infection, maternal, human immunodeficiency virus), O98.83 — Other maternal infectious and parasitic diseases complicating the puerperium (infection, maternal, specified NEC), O98.93 — Unspecified maternal infectious and parasitic disease complicating the puerperium (infection, maternal), O9A.13 — Malignant neoplasm complicating the puerperium (malignancy), O9A.23 — Injury, poisoning and certain other consequences of external causes complicating the puerperium (trauma, non-obstetric), O9A.33 — Physical abuse complicating the puerperium (trauma, non-obstetric, caused by abuse), O9A.43 — Sexual abuse complicating the puerperium (trauma, non-obstetric, caused by abuse, sexual), O9A.53 — Psychological abuse complicating the puerperium (trauma, non-obstetric, caused by abuse, psychological), Z14.01 — Asymptomatic hemophilia A carrier (genetic, hemophilia A), Z14.02 — Symptomatic hemophilia A carrier (genetic, hemophilia A, symptomatic), Z14.1 — Cystic fibrosis carrier (genetic, cystic fibrosis), Z14.8 — Genetic carrier of other disease (genetic), Z22.0 — Carrier of typhoid (typhoid), +93 more

Contextual Map

Every relationship of O99.825 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Run O99.825 with these 9 related codes in Claim Check

Hierarchy

• O00-O9A — Chapter 15: Pregnancy, Childbirth and the Puerperium (O00-O9A) (O00-O9A)[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• O94-O9A — Other obstetric conditions, not elsewhere classified[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2026

Referenced by Excludes1 notes

• Z22.330 — Carrier of Group B streptococcus[Excludes1](via O99.82.-): “Carrier of streptococcus group B (GBS) complicating pregnancy, childbirth and the puerperium (O99.82-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026

Referenced by Excludes2 notes (11)

• O20 — Hemorrhage in early pregnancy[Excludes2](via O99.-): “maternal diseases classifiable elsewhere but complicating pregnancy, labor and delivery, and the puerperium (O98-O99)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• O20-O29 — Other maternal disorders predominantly related to pregnancy (O20-O29)[Excludes2](via O99.-): “maternal diseases classifiable elsewhere but complicating pregnancy, labor and delivery, and the puerperium (O98-O99)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• O21 — Excessive vomiting in pregnancy[Excludes2](via O99.-): “maternal diseases classifiable elsewhere but complicating pregnancy, labor and delivery, and the puerperium (O98-O99)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• O22 — Venous complications and hemorrhoids in pregnancy[Excludes2](via O99.-): “maternal diseases classifiable elsewhere but complicating pregnancy, labor and delivery, and the puerperium (O98-O99)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• O23 — Infections of genitourinary tract in pregnancy[Excludes2](via O99.-): “maternal diseases classifiable elsewhere but complicating pregnancy, labor and delivery, and the puerperium (O98-O99)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• O24 — Diabetes mellitus in pregnancy, childbirth, and the puerperium[Excludes2](via O99.-): “maternal diseases classifiable elsewhere but complicating pregnancy, labor and delivery, and the puerperium (O98-O99)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• O25 — Malnutrition in pregnancy, childbirth and the puerperium[Excludes2](via O99.-): “maternal diseases classifiable elsewhere but complicating pregnancy, labor and delivery, and the puerperium (O98-O99)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• O26 — Maternal care for other conditions predominantly related to pregnancy[Excludes2](via O99.-): “maternal diseases classifiable elsewhere but complicating pregnancy, labor and delivery, and the puerperium (O98-O99)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• and 3 more

Clinical classification (CCSR)

• FAC024 — Carrier status[CCSR]— AHRQ CCSR for ICD-10-CM Diagnoses (HCUP)
• PRG027 — Complications specified during the puerperium[CCSR]— AHRQ CCSR for ICD-10-CM Diagnoses (HCUP)

MS-DRG Grouper

• DRG 769 — POSTPARTUM AND POST ABORTION DIAGNOSES WITH O.R. PROCEDURES[MS-DRG]: “POSTPARTUM AND POST ABORTION DIAGNOSES WITH O.R. PROCEDURES (MDC 14)”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026
• DRG 776 — POSTPARTUM AND POST ABORTION DIAGNOSES WITHOUT O.R. PROCEDURES[MS-DRG]: “POSTPARTUM AND POST ABORTION DIAGNOSES WITHOUT O.R. PROCEDURES (MDC 14)”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026

MDC crossing

• MDC 14 — Pregnancy, Childbirth and the Puerperium[MDC crossing]: “Pregnancy, Childbirth and the Puerperium — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs. 94 same-MDC procedures group here; browse them on the MDC page.”— CMS MS-DRG Definitions Manual · FY2026

Index entries

• Puerperal, puerperium (complicated by, complications), infection, maternal, streptococcus group Bcarrier state (GBS)[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026

Nearest codes (40)

• O99 — Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• O99.53 — Diseases of the respiratory system complicating the puerperium[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• O99.6 — Diseases of the digestive system complicating pregnancy, childbirth and the puerperium[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• O99.61 — Diseases of the digestive system complicating pregnancy[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• O99.611 — Diseases of the digestive system complicating pregnancy, first trimester[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• O99.612 — Diseases of the digestive system complicating pregnancy, second trimester[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• O99.613 — Diseases of the digestive system complicating pregnancy, third trimester[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• O99.619 — Diseases of the digestive system complicating pregnancy, unspecified trimester[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• and 32 more

Change history

• FY2016 — In the code set at ICD-10-CM adoption [Change history]— CMS release files (code change ledger) · icd10cm-fy2016

Sources for this page

Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.

Code, title, tabular notes and index terms Official source data

CMS/CDC ICD-10-CM FY2026 tabular list, index and tables, effective October 1, 2025 Release, file and checksum · Publisher’s page

Claim edits Official source data

CMS Definitions of Medicare Code Edits — v43.1 (April 2026) Release, file and checksum · Publisher’s page

Inpatient payment groups Official source data

CMS MS-DRG Definitions Manual (incl. Appendix B diagnosis index, Appendix C CC/MCC list, Appendix E procedure index) and IPPS Final Rule tables — v43 Release, file and checksum · Publisher’s page

Change history and date-of-service validity Official source data

CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page

Comparisons, relationships and the contextual map MedCoder structured relationship

Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears

Summary and FAQ answers MedCoder explanation

Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.

Labels on this page: Official source data · MedCoder structured relationship · MedCoder explanation. How to read the labels · All data sources and release dates

Nearest Codes in This Family

Official ICD-10-CM classifications closest to O99.825 in its code family, with their registry titles.

• O99.814 — Abnormal glucose complicating childbirth
• O99.815 — Abnormal glucose complicating the puerperium
• O99.82 — Streptococcus B carrier state complicating pregnancy, childbirth and the puerperium
• O99.820 — Streptococcus B carrier state complicating pregnancy
• O99.824 — Streptococcus B carrier state complicating childbirth
• O99.83 — Other infection carrier state complicating pregnancy, childbirth and the puerperium
• O99.830 — Other infection carrier state complicating pregnancy
• O99.834 — Other infection carrier state complicating childbirth
• O99.835 — Other infection carrier state complicating the puerperium
• O99.84 — Bariatric surgery status complicating pregnancy, childbirth and the puerperium

View all codes in the O99 family