541 MS-DRG: OSTEOMYELITIS WITHOUT CC/MCC
MS-DRG 541 groups Medicare inpatient hospital stays for: OSTEOMYELITIS WITHOUT CC/MCC. This is a medical MS-DRG. It falls under MDC 08 (Diseases and Disorders of the Musculoskeletal System and Connective Tissue).
Payment & Classification Data
Official CMS values from the FY2027 IPPS Final Rule Table 5.
| Major Diagnostic Category | MDC 08 — Diseases and Disorders of the Musculoskeletal System and Connective Tissue |
| DRG Type | Medical |
| Severity Level | None |
| Relative Weight | 0.8297 |
| Relative Weight (10% Cap Applied) | 0.8297 |
| Geometric Mean Length of Stay | 2.8 days |
| Arithmetic Mean Length of Stay | 3.7 days |
| Post-Acute Transfer DRG | Yes |
| Special Pay Transfer DRG | No |
Defining Codes (FY2027)
220 diagnosis codes can drive assignment here: A02.24, A18.01, A18.03, A51.46, A52.77, A54.41, M46.20, M46.21, M46.22, M46.23, M46.24, M46.25 and 208 more.
From the CMS MS-DRG Definitions Manual (Appendices B and E). Assignment also depends on severity, discharge status and the rest of the claim.
Contextual Map
Every relationship of 541 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.
Major Diagnostic Category
- MDC 08 — Diseases and Disorders of the Musculoskeletal System and Connective Tissue[MDC]— CMS MS-DRG Definitions Manual · FY2027
Defining diagnoses (220)
- A02.24 — Salmonella osteomyelitis[Grouper diagnosis]— CMS MS-DRG Definitions Manual (Appendix B) · FY2027
- A18.01 — Tuberculosis of spine[Grouper diagnosis]— CMS MS-DRG Definitions Manual (Appendix B) · FY2027
- A18.03 — Tuberculosis of other bones[Grouper diagnosis]— CMS MS-DRG Definitions Manual (Appendix B) · FY2027
- A51.46 — Secondary syphilitic osteopathy[Grouper diagnosis]— CMS MS-DRG Definitions Manual (Appendix B) · FY2027
- A52.77 — Syphilis of bone and joint[Grouper diagnosis]— CMS MS-DRG Definitions Manual (Appendix B) · FY2027
- A54.41 — Gonococcal spondylopathy[Grouper diagnosis]— CMS MS-DRG Definitions Manual (Appendix B) · FY2027
- M46.20 — Osteomyelitis of vertebra, site unspecified[Grouper diagnosis]— CMS MS-DRG Definitions Manual (Appendix B) · FY2027
- M46.21 — Osteomyelitis of vertebra, occipito-atlanto-axial region[Grouper diagnosis]— CMS MS-DRG Definitions Manual (Appendix B) · FY2027
- and 212 more
DRG family
- DRG 539 — OSTEOMYELITIS WITH MCC[DRG family]: “OSTEOMYELITIS WITH MCC — same CMS DRG family (539-541), split by severity.”— CMS MS-DRG Definitions Manual (DRG family 539-541) · FY2027
- DRG 540 — OSTEOMYELITIS WITH CC[DRG family]: “OSTEOMYELITIS WITH CC — same CMS DRG family (539-541), split by severity.”— CMS MS-DRG Definitions Manual (DRG family 539-541) · FY2027
Read from: CMS MS-DRG Definitions Manual (incl. Appendix B diagnosis index, Appendix C CC/MCC list, Appendix E procedure index) and IPPS Final Rule tables — v44. All data sources · How to read the labels