542 MS-DRG: PATHOLOGICAL FRACTURES AND MUSCULOSKELETAL AND CONNECTIVE TISSUE MALIGNANCY WITH MCC
MS-DRG 542 groups Medicare inpatient hospital stays for: PATHOLOGICAL FRACTURES AND MUSCULOSKELETAL AND CONNECTIVE TISSUE MALIGNANCY WITH MCC. This is a medical MS-DRG. It falls under MDC 08 (Diseases and Disorders of the Musculoskeletal System and Connective Tissue).
Payment & Classification Data
Official CMS values from the FY2027 IPPS Final Rule Table 5.
| Major Diagnostic Category | MDC 08 — Diseases and Disorders of the Musculoskeletal System and Connective Tissue |
| DRG Type | Medical |
| Severity Level | MCC |
| Relative Weight | 1.7211 |
| Relative Weight (10% Cap Applied) | 1.7211 |
| Geometric Mean Length of Stay | 4.9 days |
| Arithmetic Mean Length of Stay | 6.6 days |
| Post-Acute Transfer DRG | Yes |
| Special Pay Transfer DRG | No |
Defining Codes (FY2027)
280 diagnosis codes can drive assignment here: C40.00, C40.01, C40.02, C40.10, C40.11, C40.12, C40.20, C40.21, C40.22, C40.30, C40.31, C40.32 and 268 more.
From the CMS MS-DRG Definitions Manual (Appendices B and E). Assignment also depends on severity, discharge status and the rest of the claim.
Contextual Map
Every relationship of 542 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.
Major Diagnostic Category
- MDC 08 — Diseases and Disorders of the Musculoskeletal System and Connective Tissue[MDC]— CMS MS-DRG Definitions Manual · FY2027
Defining diagnoses (280)
- C40.00 — Malignant neoplasm of scapula and long bones of unspecified upper limb[Grouper diagnosis]— CMS MS-DRG Definitions Manual (Appendix B) · FY2027
- C40.01 — Malignant neoplasm of scapula and long bones of right upper limb[Grouper diagnosis]— CMS MS-DRG Definitions Manual (Appendix B) · FY2027
- C40.02 — Malignant neoplasm of scapula and long bones of left upper limb[Grouper diagnosis]— CMS MS-DRG Definitions Manual (Appendix B) · FY2027
- C40.10 — Malignant neoplasm of short bones of unspecified upper limb[Grouper diagnosis]— CMS MS-DRG Definitions Manual (Appendix B) · FY2027
- C40.11 — Malignant neoplasm of short bones of right upper limb[Grouper diagnosis]— CMS MS-DRG Definitions Manual (Appendix B) · FY2027
- C40.12 — Malignant neoplasm of short bones of left upper limb[Grouper diagnosis]— CMS MS-DRG Definitions Manual (Appendix B) · FY2027
- C40.20 — Malignant neoplasm of long bones of unspecified lower limb[Grouper diagnosis]— CMS MS-DRG Definitions Manual (Appendix B) · FY2027
- C40.21 — Malignant neoplasm of long bones of right lower limb[Grouper diagnosis]— CMS MS-DRG Definitions Manual (Appendix B) · FY2027
- and 272 more
DRG family
- DRG 543 — PATHOLOGICAL FRACTURES AND MUSCULOSKELETAL AND CONNECTIVE TISSUE MALIGNANCY WITH CC[DRG family]: “PATHOLOGICAL FRACTURES AND MUSCULOSKELETAL AND CONNECTIVE TISSUE MALIGNANCY WITH CC — same CMS DRG family (542-544), split by severity.”— CMS MS-DRG Definitions Manual (DRG family 542-544) · FY2027
- DRG 544 — PATHOLOGICAL FRACTURES AND MUSCULOSKELETAL AND CONNECTIVE TISSUE MALIGNANCY WITHOUT CC/MCC[DRG family]: “PATHOLOGICAL FRACTURES AND MUSCULOSKELETAL AND CONNECTIVE TISSUE MALIGNANCY WITHOUT CC/MCC — same CMS DRG family (542-544), split by severity.”— CMS MS-DRG Definitions Manual (DRG family 542-544) · FY2027
Read from: CMS MS-DRG Definitions Manual (incl. Appendix B diagnosis index, Appendix C CC/MCC list, Appendix E procedure index) and IPPS Final Rule tables — v44. All data sources · How to read the labels · How MedCoder verifies its implementation
Current data releases:ICD-10-CM FY2027 · ICD-10-PCS FY2027 · HCPCS October 2026 · MS-DRG v44 · Medicare Code Editor v44.0 · NCCI PTP Q4 2026 · MUE Q4 2026 · NCD code lists 2026-01 · LCD export September 28, 2026 · All releases and sources