Otrexup

NDC 54436-022 · Antares Pharma, Inc.

Generic namemethotrexate

Dosage formINJECTION, SOLUTION

RouteSUBCUTANEOUS

Active ingredient(s)METHOTREXATE

Strength22.5 mg/.4mL

Pharmacologic classFolate Analog Metabolic Inhibitor [EPC], Folic Acid Metabolism Inhibitors [MoA]

Marketing categoryNDA

Packages

54436-022-01 — 1 SYRINGE in 1 CARTON (54436-022-01) / .4 mL in 1 SYRINGE

54436-022-03 — 1 SYRINGE in 1 CARTON (54436-022-03) / .4 mL in 1 SYRINGE

54436-022-04 — 4 SYRINGE in 1 CARTON (54436-022-04) / .4 mL in 1 SYRINGE (54436-022-02)

FDA lists these products with the same active ingredient.

0143-9367 — Methotrexate, 0143-9516 — Methotrexate, 0143-9517 — Methotrexate, 0143-9518 — Methotrexate, 0143-9519 — Methotrexate, 0143-9830 — Methotrexate, 0904-7141 — Methotrexate, 16729-277 — Methotrexate, 50268-554 — Methotrexate, 52652-2001 — Methotrexate, 54436-010 — methotrexate, 54436-012 — methotrexate, 54436-015 — methotrexate, 54436-017 — methotrexate, 54436-020 — methotrexate, 54436-025 — methotrexate, 68382-775 — Methotrexate, 70771-1058 — Methotrexate, 81927-204 — Methotrexate

From the FDA National Drug Code Directory, retrieved 2026-08-24. Product listings are submitted by labelers; FDA does not verify them.