Hydrocodone/APAP

NDC 72189-650 · Direct_Rx

Generic nameHydrocodone/APAP

Dosage formTABLET

RouteORAL

Active ingredient(s)HYDROCODONE BITARTRATE, ACETAMINOPHEN

Strength325; 10 mg/1; mg/1

Pharmacologic classOpioid Agonist [EPC], Opioid Agonists [MoA]

DEA scheduleCII

Marketing categoryANDA

Packages

72189-650-30 — 30 TABLET in 1 BOTTLE (72189-650-30)

72189-650-60 — 60 TABLET in 1 BOTTLE (72189-650-60)

Related Codes

Same active ingredient

FDA lists these products with the same active ingredient.

72189-375 — Oxycodone/APAP, 72189-376 — Acetaminophen and Codeine Phosphate, 72189-382 — Tramadol Hydrochloride and Acetaminophen, 72189-397 — Oxycodone/APAP, 72189-399 — Hydrocodone/APAP, 72189-406 — HYDROCODONE/APAP, 72189-407 — Hydrocodone/APAP, 72189-441 — Butal/APAP/Caff, 72189-600 — BUTAL/APAP/CAFFEINE, 72189-649 — Hydrocodone/APAP, 72189-671 — Tramadol/APAP, 72245-193 — oxycodone and acetaminophen, 72245-648 — oxycodone hydrochloride and acetaminophen, 72245-681 — oxycodone and acetaminophen, 72245-682 — oxycodone and acetaminophen, 72245-683 — oxycodone and acetaminophen, 72260-129 — ACETAMINOPHEN and IBUPROFEN, 72288-008 — Acetaminophen, 72288-056 — Acetaminophen, Dextromethorphan HBr, Doxylamine succinate, 72288-105 — Acetaminophen, +3514 more

From the FDA National Drug Code Directory, retrieved August 24, 2026. Product listings are submitted by labelers; FDA does not verify them.

Read from: FDA National Drug Code Directory, product.txt and package.txt (accessdata.fda.gov/cder/ndctext.zip) — Snapshot retrieved 2026-08-24, loaded 2026-08-24; CMS Medicare Part B Drug Average Sales Price (ASP) Pricing Files (cms.gov/medicare/payment/part-b-drugs/asp-pricing-files) -- the NDC-HCPCS crosswalk and Part B payment limit files — 2026 Q4 (October 2026 release). All data sources · How to read the labels

Current data releases:ICD-10-CM FY2027 · ICD-10-PCS FY2027 · HCPCS October 2026 · MS-DRG v44 · Medicare Code Editor v44.0 · NCCI PTP Q4 2026 · MUE Q4 2026 · NCD code lists 2026-01 · LCD export September 28, 2026 · All releases and sources