C22 vs C78.7
C22 (Malignant neoplasm of liver and intrahepatic bile ducts) compared with C78.7 (Secondary malignant neoplasm of liver and intrahepatic bile duct), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.
Can these codes be reported together?
No — do not report together. C22 carries an Excludes1 note covering C78.7: “secondary malignant neoplasm of liver and intrahepatic bile duct (C78.7)”
Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
Side by side
| C22Malignant neoplasm of liver and intrahepatic bile ducts | C78.7Secondary malignant neoplasm of liver and intrahepatic bile duct | |
|---|---|---|
| Billing status | Non-billable header | Billable |
| Classification | C00-D49 — Neoplasms (C00-D49) | C00-D49 — Neoplasms (C00-D49) |
| Definition | Malignant neoplasm of liver and intrahepatic bile ducts is a non-billable ICD-10-CM category code (C22). | Secondary malignant neoplasm of liver and intrahepatic bile duct is a billable ICD-10-CM diagnosis code (C78.7). |
| Use additional code | code to identify: alcohol abuse and dependence (F10.-) hepatitis B (B16.-, B18.0-B18.1) | — |
Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources