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C49.3 vs C57.3

C49.3 (Malignant neoplasm of connective and soft tissue of thorax) compared with C57.3 (Malignant neoplasm of parametrium), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).

Can these codes be reported together?

Yes, when both are documented. C49.3 carries an Excludes2 note covering C57.3: “malignant neoplasm of uterine ligament (C57.3)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

Side by side

C49.3Malignant neoplasm of connective and soft tissue of thoraxC57.3Malignant neoplasm of parametrium
Billing statusBillableBillable
ClassificationC00-D49 — Neoplasms (C00-D49)C00-D49 — Neoplasms (C00-D49)
DefinitionMalignant neoplasm of connective and soft tissue of thorax is a billable ICD-10-CM diagnosis code (C49.3).Malignant neoplasm of parametrium is a billable ICD-10-CM diagnosis code (C57.3).
Includes
malignant neoplasm of blood vessel
malignant neoplasm of bursa
malignant neoplasm of cartilage
malignant neoplasm of fascia
malignant neoplasm of skin of female genital organs
Malignant neoplasm of uterine ligament NOS

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources