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C57.3 ICD-10-CM Code: Malignant neoplasm of parametrium

Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.

Coding at a Glance

Tabular directives
2 inclusion terms
Risk adjustment
CMS-HCC V28: 1 category · CMS-HCC V22 category 10 · RxHCC V08 category 22

Inpatient Payment Groups (MS-DRG)

Potential MS-DRG participation — not a DRG assignment.

MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v43, Appendix B.

  • MS-DRG 736 — UTERINE AND ADNEXA PROCEDURES FOR OVARIAN OR ADNEXAL MALIGNANCY WITH MCC (MDC 13)
  • MS-DRG 737 — UTERINE AND ADNEXA PROCEDURES FOR OVARIAN OR ADNEXAL MALIGNANCY WITH CC (MDC 13)
  • MS-DRG 738 — UTERINE AND ADNEXA PROCEDURES FOR OVARIAN OR ADNEXAL MALIGNANCY WITHOUT CC/MCC (MDC 13)
  • MS-DRG 739 — UTERINE AND ADNEXA PROCEDURES FOR NON-OVARIAN AND NON-ADNEXAL MALIGNANCY WITH MCC (MDC 13)
  • MS-DRG 740 — UTERINE AND ADNEXA PROCEDURES FOR NON-OVARIAN AND NON-ADNEXAL MALIGNANCY WITH CC (MDC 13)
  • MS-DRG 741 — UTERINE AND ADNEXA PROCEDURES FOR NON-OVARIAN AND NON-ADNEXAL MALIGNANCY WITHOUT CC/MCC (MDC 13)
  • MS-DRG 754 — MALIGNANCY, FEMALE REPRODUCTIVE SYSTEM WITH MCC (MDC 13)
  • MS-DRG 755 — MALIGNANCY, FEMALE REPRODUCTIVE SYSTEM WITH CC (MDC 13)
  • MS-DRG 756 — MALIGNANCY, FEMALE REPRODUCTIVE SYSTEM WITHOUT CC/MCC (MDC 13)

A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.

Risk Adjustment (CMS-HCC)

Payment categories this diagnosis maps to under CMS-HCC V28, payment year 2026.

  • HCC 22 — Bladder, Colorectal, and Other Cancers (supersedes HCC 23)

Other models: CMS-HCC V22 HCC 10 · RxHCC V08 HCC 22

Risk scores depend on the enrollee's full accepted diagnosis set and segment; a category mapping alone does not determine payment.

Coding instructions

Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for C57.3 in the official ICD-10-CM tabular list, quoted as published.

Source: CMS/CDC — ICD-10-CM Tabular ListRelease: FY2026Effective: October 1, 2025

Notes without a marker are published on C57.3 itself; “inherited from” names the category or block whose note applies here.

Includes

Conditions the official ICD-10-CM tabular list includes under this code.

  • malignant neoplasm of skin of female genital organs

Source: inherited from C51-C58

Inclusion Terms

Alternative terms the tabular list files under this code.

  • Malignant neoplasm of uterine ligament NOS

Coder workflow for C57.3

MedCoder structured workflow — derived from this code’s own official record

Before you code C57.3

  1. Confirm the documented site and behavior (this code’s block classifies malignant neoplasms), whether the site is primary or secondary, and whether the malignancy is current or a personal history: a previously excised malignancy with no further treatment and no evidence of disease is history, not current disease. Verify the site against the Table of Neoplasms. Neoplasm chapter guidelines (Guidelines I.C.2.a, I.C.2.d, I.C.2.m).

    See the Table of Neoplasms entries · Guide: Active cancer vs history of cancer →

Documentation check

The provider’s diagnostic statement
Codes are assigned from the provider’s documented diagnosis, not from clinical criteria, test values or a medication list (Guidelines I.A.19).
Anatomical site
At the most specific level the record states; a site the classification separates cannot be assumed from a procedure or a measurement.
Behavior and current-versus-history status
Malignant, in situ, benign or uncertain; primary or secondary; current disease or personal history (Guidelines I.C.2.m).

Every row is derived from this code’s own record — its title, tabular notes, 7th-character family and same-category siblings — with fixed MedCoder wording; nothing is inferred about a patient. The official notes and guideline text are in the sections each row links to, and they control.

Code Overview

Malignant neoplasm of parametrium is a billable ICD-10-CM diagnosis code (C57.3).

MedCoder summary Summary composed by MedCoder from this code's official ICD-10-CM record. The tabular instructional notes themselves appear verbatim below.

Neoplasm Table Sites (7)

Official source data — entries quoted as published, in the Index’s own lookup phrasing

Anatomical sites from the official ICD-10-CM Table of Neoplasms that map to this code, with the matching behavior column.

  • Neoplasm, neoplastic, ligament, sacro-uterine — Malignant, Primary
  • Neoplasm, neoplastic, ligament, uterine — Malignant, Primary
  • Neoplasm, neoplastic, ligament, uterosacral — Malignant, Primary
  • Neoplasm, neoplastic, parametrium — Malignant, Primary
  • Neoplasm, neoplastic, sacrouterine ligament — Malignant, Primary
  • Neoplasm, neoplastic, uterosacral ligament — Malignant, Primary
  • Neoplasm, neoplastic, uterus, uteri, uterine, ligament — Malignant, Primary

Verify Before Coding

  • No Medicare Code Editor or MS-DRG Definitions Manual restrictions apply to this code.

From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.

Relationships & Classification

MedCoder structured relationships — computed from published CMS and AHRQ datasets

Other codes that name C57.3 or its code family, from the CMS ICD-10-CM tabular instructional notes, the CMS Table of Neoplasms and the CMS Table of Neoplasms (site match derived from the code title). Tabular-note edges are stored at the code family level that carries each note.

Referenced by 1 Excludes2 note: C49 — Malignant neoplasm of other connective and soft tissue.

These codes’ tabular lists name this diagnosis as distinct — both may be reported when both are documented.

Referenced by 4 Same-site neoplasm codes: C79.82 — Secondary malignant neoplasm of genital organsCompare C57.3 vs C79.82 →, D28.2 — Benign neoplasm of uterine tubes and ligamentsCompare C57.3 vs D28.2 →, D39.8 — Neoplasm of uncertain behavior of other specified female genital organsCompare C57.3 vs D39.8 →, D49.59 — Neoplasm of unspecified behavior of other genitourinary organCompare C57.3 vs D49.59 →.

These codes represent related neoplasm behaviors affecting the same anatomic site.

Referenced by 1 Screening & history code: Z85.42 — Personal history of malignant neoplasm of other parts of uterusCompare C57.3 vs Z85.42 →.

These codes represent screening tests and history codes that refer to this active disease condition.

MS-DRG Grouper Relationships (FY2026)

Potential MS-DRG participation — not a DRG assignment.

FY2026 MS-DRG: not on the CMS CC/MCC list — as a secondary diagnosis this code does not change MS-DRG severity for that release.

Named in the grouper logic of 9 MS-DRGs: DRG 736 (MDC 13), DRG 737 (MDC 13), DRG 738 (MDC 13), DRG 739 (MDC 13), DRG 740 (MDC 13), DRG 741 (MDC 13), DRG 754 (MDC 13), DRG 755 (MDC 13), DRG 756 (MDC 13).

From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.

Clinical classification (AHRQ CCSR):NEO038 — Female reproductive system cancers - all other types (default).

Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.

Related Codes

Same CMS-HCC risk category (V28)

CMS maps these diagnoses to the same Hierarchical Condition Category (Bladder, Colorectal, and Other Cancers) for risk-adjusted payment.

C56.9 — Malignant neoplasm of unspecified ovary, C57.00 — Malignant neoplasm of unspecified fallopian tube, C57.01 — Malignant neoplasm of right fallopian tube, C57.02 — Malignant neoplasm of left fallopian tube, C57.10 — Malignant neoplasm of unspecified broad ligament, C57.11 — Malignant neoplasm of right broad ligament, C57.12 — Malignant neoplasm of left broad ligament, C57.20 — Malignant neoplasm of unspecified round ligament, C57.21 — Malignant neoplasm of right round ligament, C57.22 — Malignant neoplasm of left round ligament, C57.4 — Malignant neoplasm of uterine adnexa, unspecified, C57.7 — Malignant neoplasm of other specified female genital organs, C57.8 — Malignant neoplasm of overlapping sites of female genital organs, C57.9 — Malignant neoplasm of female genital organ, unspecified, C58 — Malignant neoplasm of placenta, C64.1 — Malignant neoplasm of right kidney, except renal pelvis, C64.2 — Malignant neoplasm of left kidney, except renal pelvis, C64.9 — Malignant neoplasm of unspecified kidney, except renal pelvis, C65.1 — Malignant neoplasm of right renal pelvis, C65.2 — Malignant neoplasm of left renal pelvis, +105 more

Related risk categories

These categories interact through CMS's HCC hierarchy — one can suppress the other's risk-adjustment weight when both are present on a claim.

Cancer Metastatic to Lung, Liver, Brain, and Other Organs; Acute Myeloid Leukemia Except Promyelocytic, Cancer Metastatic to Bone, Other and Unspecified Metastatic Cancer; Acute Leukemia Except Myeloid, Myelodysplastic Syndromes, Multiple Myeloma, and Other Cancers, Lung and Other Severe Cancers, Lymphoma and Other Cancers, Prostate, Breast, and Other Cancers and Tumors

Same clinical category (CCSR)

AHRQ's Clinical Classifications Software groups these diagnoses under the same clinical category (Female reproductive system cancers - all other types).

C51.0 — Malignant neoplasm of labium majus, C51.1 — Malignant neoplasm of labium minus, C51.2 — Malignant neoplasm of clitoris, C51.8 — Malignant neoplasm of overlapping sites of vulva, C57.10 — Malignant neoplasm of unspecified broad ligament, C57.11 — Malignant neoplasm of right broad ligament, C57.12 — Malignant neoplasm of left broad ligament, C57.20 — Malignant neoplasm of unspecified round ligament, C57.21 — Malignant neoplasm of right round ligament, C57.22 — Malignant neoplasm of left round ligament, C57.4 — Malignant neoplasm of uterine adnexa, unspecified, C57.7 — Malignant neoplasm of other specified female genital organs, C57.8 — Malignant neoplasm of overlapping sites of female genital organs, C57.9 — Malignant neoplasm of female genital organ, unspecified, C58 — Malignant neoplasm of placenta, D07.30 — Carcinoma in situ of unspecified female genital organs, D07.39 — Carcinoma in situ of other female genital organs

Lab tests where this diagnosis supports Medicare coverage (NCD)

Medicare's National Coverage Determination (NCD) program lists this diagnosis as medical justification for these lab tests.

Gamma-glutamyl Transferase (GGT) Test, Iron Panel

Contextual Map

Every relationship of C57.3 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Run C57.3 with this related code in Claim Check

Hierarchy

Same site

Referenced by Excludes2 notes

Referenced by Same-site neoplasm codes

Referenced by Screening & history codes MedCoder-derived

Clinical classification (CCSR)

Risk adjustment (CMS-HCC)

  • HCC 22 — Bladder, Colorectal, and Other Cancers [CMS-HCC]: “Bladder, Colorectal, and Other Cancers — supersedes HCC 23 (Prostate, Breast, and Other Cancers and Tumors)”— CMS-HCC V28 · 2026

MS-DRG Grouper (9)

MDC crossing

  • MDC 13 — Diseases and Disorders of the Female Reproductive System[MDC crossing]: “Diseases and Disorders of the Female Reproductive System — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs. 2,232 same-MDC procedures group here; browse them on the MDC page.”— CMS MS-DRG Definitions Manual · FY2026

Neoplasm sites

  • Neoplasm, neoplastic, ligament, sacro-uterine — Neoplasm, neoplastic, ligament, sacro-uterine — Malignant, Primary [Neoplasm table]: “Neoplasm, neoplastic, ligament, sacro-uterine (Malignant, Primary)”— CMS Table of Neoplasms · icd10cm-fy2026
  • Neoplasm, neoplastic, ligament, uterine — Neoplasm, neoplastic, ligament, uterine — Malignant, Primary [Neoplasm table]: “Neoplasm, neoplastic, ligament, uterine (Malignant, Primary)”— CMS Table of Neoplasms · icd10cm-fy2026
  • Neoplasm, neoplastic, ligament, uterosacral — Neoplasm, neoplastic, ligament, uterosacral — Malignant, Primary [Neoplasm table]: “Neoplasm, neoplastic, ligament, uterosacral (Malignant, Primary)”— CMS Table of Neoplasms · icd10cm-fy2026
  • Neoplasm, neoplastic, parametrium — Neoplasm, neoplastic, parametrium — Malignant, Primary [Neoplasm table]: “Neoplasm, neoplastic, parametrium (Malignant, Primary)”— CMS Table of Neoplasms · icd10cm-fy2026
  • Neoplasm, neoplastic, sacrouterine ligament — Neoplasm, neoplastic, sacrouterine ligament — Malignant, Primary [Neoplasm table]: “Neoplasm, neoplastic, sacrouterine ligament (Malignant, Primary)”— CMS Table of Neoplasms · icd10cm-fy2026
  • Neoplasm, neoplastic, uterosacral ligament — Neoplasm, neoplastic, uterosacral ligament — Malignant, Primary [Neoplasm table]: “Neoplasm, neoplastic, uterosacral ligament (Malignant, Primary)”— CMS Table of Neoplasms · icd10cm-fy2026
  • Neoplasm, neoplastic, uterus, uteri, uterine, ligament — Neoplasm, neoplastic, uterus, uteri, uterine, ligament — Malignant, Primary [Neoplasm table]: “Neoplasm, neoplastic, uterus, uteri, uterine, ligament (Malignant, Primary)”— CMS Table of Neoplasms · icd10cm-fy2026

Nearest codes (17)

Change history

  • FY2016 — In the code set at ICD-10-CM adoption [Change history]— CMS release files (code change ledger) · icd10cm-fy2016

Sources for this page

Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.

Code, title, tabular notes and index terms Official source data
CMS/CDC ICD-10-CM FY2026 tabular list, index and tables, effective October 1, 2025 Release, file and checksum · Publisher’s page
Claim edits Official source data
CMS Definitions of Medicare Code Edits — v43.1 (April 2026) Release, file and checksum · Publisher’s page
Inpatient payment groups Official source data
CMS MS-DRG Definitions Manual (incl. Appendix B diagnosis index, Appendix C CC/MCC list, Appendix E procedure index) and IPPS Final Rule tables — v43 Release, file and checksum · Publisher’s page
Risk adjustment Official source data
2026 Mid-Year Final ICD-10 Mappings + Model Software (cms.gov/files/zip/2026-midyear-final-icd-10-mappings.zip, 2026-midyear-final-model-software.zip) — CMS-HCC V28, PY2026 mid-year final release Release, file and checksum · Publisher’s page
Change history and date-of-service validity Official source data
CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page
Comparisons, relationships and the contextual map MedCoder structured relationship
Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears
Summary and FAQ answers MedCoder explanation
Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.

Labels on this page: Official source data · MedCoder structured relationship · MedCoder explanation. How to read the labels · All data sources and release dates

Cite this page

Reference this page in a research guide, syllabus or article. The release is included because code content changes each year.

MedCoder.ai. "C57.3 — Malignant neoplasm of parametrium." ICD-10-CM FY2026. https://medcoder.ai/icd10/code/c57.3-malignant-neoplasm-of-parametrium

Change history

  • FY2016 — October 1, 2015
    In the code set at ICD-10-CM adoption
    Malignant neoplasm of parametrium

No changes since FY2016 — additions, deletions, description changes and billable-status changes are tracked through FY2027 (effective October 1, 2026), and none are recorded for this code. Note changes are tracked from FY2027 only.

Nearest Codes in This Family

Official ICD-10-CM classifications closest to C57.3 in its code family, with their registry titles.

View all codes in the C57 family