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Compare/E23.0 vs E28

E23.0 vs E28

E23.0 (Hypopituitarism) compared with E28 (Ovarian dysfunction), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.

Can these codes be reported together?

No — do not report together. E28 carries an Excludes1 note covering E23.0: “isolated gonadotropin deficiency (E23.0)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Side by side

E23.0HypopituitarismE28Ovarian dysfunction
Billing statusBillableNon-billable header

Report instead: E28.0, E28.1, E28.2, E28.310, E28.319

ClassificationE00-E89 — Endocrine, Nutritional and Metabolic Diseases (E00-E89)E00-E89 — Endocrine, Nutritional and Metabolic Diseases (E00-E89)
DefinitionHypopituitarism is a billable ICD-10-CM diagnosis code (E23.0).Ovarian dysfunction is a non-billable ICD-10-CM category code (E28).
Includes
the listed conditions whether the disorder is in the pituitary or the hypothalamus
Fertile eunuch syndrome
Hypogonadotropic hypogonadism
Idiopathic growth hormone deficiency
Use additional code
code, if applicable, for associated cachexia (E88.A)

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources