T78.2XXD vs T88.6
T78.2XXD (Anaphylactic shock, unspecified, subsequent encounter) compared with T88.6 (Anaphylactic reaction due to adverse effect of correct drug or medicament properly administered), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.
Can these codes be reported together?
No — do not report together. T78.2XXD carries an Excludes1 note covering T88.6: “anaphylactic reaction or shock due to adverse effect of correct medicinal substance properly administered (T88.6)”
Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
Yes, when both are documented. T78.2XXD carries an Excludes2 note covering T88.6: “complications of surgical and medical care NEC (T80-T88)”
Excludes2 marks distinct conditions — both may be reported when both are documented.
Side by side
| T78.2XXDAnaphylactic shock, unspecified, subsequent encounter | T88.6Anaphylactic reaction due to adverse effect of correct drug or medicament properly administered | |
|---|---|---|
| Billing status | Billable | Non-billable header |
| Classification | S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88) | S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88) |
| Definition | Anaphylactic shock, unspecified, subsequent encounter is a billable ICD-10-CM diagnosis code (T78.2D). | Anaphylactic reaction due to adverse effect of correct drug or medicament properly administered is a non-billable ICD-10-CM category code (T88.6). |
| 7th character | The appropriate 7th character is to be added to each code from category T78 | The appropriate 7th character is to be added to each code from category T88 |
| Includes | Allergic shock Anaphylactic reaction Anaphylaxis | Anaphylactic shock due to adverse effect of correct drug or medicament properly administered Anaphylactoid reaction NOS |
| Use additional code | — | code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5) code(s) to identify the specified condition resulting from the complication code to identify devices involved and details of circumstances (Y62-Y82) |
Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources