T78.2XXD ICD-10-CM Code: Anaphylactic shock, unspecified, subsequent encounter
Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.
Inpatient Payment Groups (MS-DRG)
MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v43.0, Appendix B.
- MS-DRG 949 — AFTERCARE WITH CC/MCC (MDC 23)
- MS-DRG 950 — AFTERCARE WITHOUT CC/MCC (MDC 23)
A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.
Official Registry Overview & Definition
Official Tabular Instructional Notes
Sequencing, inclusion, and exclusion notes published for T78.2XXD in the official ICD-10-CM tabular list.
Inclusion Terms
Alternative terms the tabular list files under this code.
- Allergic shock
- Anaphylactic reaction
- Anaphylaxis
Excludes1 — Not Coded Here
Conditions generally not reported together with this code (Excludes1) -- an error unless the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
- anaphylactic reaction or shock due to adverse effect of correct medicinal substance properly administered (T88.6) Compare T78.2XXD vs T88.6 →
- anaphylactic reaction or shock due to adverse food reaction (T78.0-) Compare T78.2XXD vs T78.0 →
- anaphylactic reaction or shock due to serum (T80.5-) Compare T78.2XXD vs T80.5 →
Excludes2 — Not Included Here
Conditions not covered by this code, but which may be reported alongside it when both are present.
- complications of surgical and medical care NEC (T80-T88) Compare T78.2XXD vs T80 →
Code Also
Additional codes that may be required to fully describe the encounter.
- Code also, if applicable, place of occurrence, such as:
- highway rest stop (Y92.523)
- school (private) (public) (state) as the place of occurrence of the external cause (Y92.21-)
- service areas as the place of occurrence of the external cause (Y92.52-)
- single-family non-institutional (private) house as the place of occurrence of the external cause (Y92.01-)
- transport vehicle as the place of occurrence of the external cause (Y92.81-)
Change history
No changes recorded for this code — unchanged since the FY2016 baseline of the change ledger.
Verify Before Coding
- Billable — reportable as written.
From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim.
Contextual Map
Every relationship of T78.2XXD in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.
Hierarchy
- T78.2 — Anaphylactic shock, unspecified [Hierarchy]
Referenced by Excludes1 notes
- T75 — Other and unspecified effects of other external causes [Excludes1](via T78.-): “adverse effects NEC (T78.-)”
Clinical classification (CCSR)
- INJ067 — Allergic reactions, subsequent encounter [CCSR]
Potential MS-DRG
- DRG 949 — AFTERCARE WITH CC/MCC [MS-DRG]: “AFTERCARE WITH CC/MCC (MDC 23)”
- DRG 950 — AFTERCARE WITHOUT CC/MCC [MS-DRG]: “AFTERCARE WITHOUT CC/MCC (MDC 23)”
Nearest codes (40)
- T78 — Adverse effects, not elsewhere classified [Sibling]
- T78.119S — Other adverse food reaction due to milk and dairy products with baked milk tolerance/reactivity, unspecified, sequela [Sibling]
- T78.12 — Other adverse food reaction due to eggs [Sibling]
- T78.120 — Other adverse food reaction due to egg with tolerance to baked egg [Sibling]
- T78.120A — Other adverse food reaction due to egg with tolerance to baked egg, initial encounter [Sibling]
- T78.120D — Other adverse food reaction due to egg with tolerance to baked egg, subsequent encounter [Sibling]
- T78.120S — Other adverse food reaction due to egg with tolerance to baked egg, sequela [Sibling]
- T78.121 — Other adverse food reaction due to egg with reactivity to baked egg [Sibling]
- and 32 more
Referenced by Other Codes
Clinical classification (AHRQ CCSR):INJ067 — Allergic reactions, subsequent encounter (default).
Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.
Potential MS-DRG Relationships (FY2026)
Not on the CMS CC/MCC list — as a secondary diagnosis this code does not change MS-DRG severity.
Named in the grouper logic of 2 MS-DRGs: DRG 949 (MDC 23), DRG 950 (MDC 23).
From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.
Official ICD-10-CM tabular notes on other codes that name T78.2XXD or its code family.
1 Excludes1 notes: T75 (via T78.-).
Frequently Asked Questions (FAQ) & Clinical Guidance
Does T78.2XXD require a 7th character?
Yes. The appropriate 7th character is to be added to each code from category T78.
Nearest Codes in This Family
Official ICD-10-CM classifications closest to T78.2XXD in its code family, with their registry titles.
- T78.19XA — Other adverse food reactions, not elsewhere classified, initial encounter
- T78.19XD — Other adverse food reactions, not elsewhere classified, subsequent encounter
- T78.19XS — Other adverse food reactions, not elsewhere classified, sequela
- T78.2 — Anaphylactic shock, unspecified
- T78.2XXA — Anaphylactic shock, unspecified, initial encounter
- T78.2XXS — Anaphylactic shock, unspecified, sequela
- T78.3 — Angioneurotic edema
- T78.3XXA — Angioneurotic edema, initial encounter
- T78.3XXD — Angioneurotic edema, subsequent encounter
- T78.3XXS — Angioneurotic edema, sequela