T78.41XA (Arthus phenomenon, initial encounter) compared with T80 (Complications following infusion, transfusion and therapeutic injection), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).
Distinct conditions — both may be reported.
“complications of surgical and medical care NEC (T80-T88)”
An Excludes2 note means the excluded condition is not part of the code above it, but a patient can have both. Report both when both are documented.
Source: CMS ICD-10-CM tabular instructional notes
Yes, when both are documented. T78.41XA carries an Excludes2 note covering T80: “complications of surgical and medical care NEC (T80-T88)”
Excludes2 marks distinct conditions — both may be reported when both are documented.
| T78.41XAArthus phenomenon, initial encounter | T80Complications following infusion, transfusion and therapeutic injection | |
|---|---|---|
| Billing status | Billable | Non-billable header Report instead: T80.0XXA, T80.0XXD, T80.0XXS, T80.1XXA, T80.1XXD |
| Classification | S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88) | S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88) |
| Definition | Arthus phenomenon, initial encounter is a billable ICD-10-CM diagnosis code (T78.41A). | Complications following infusion, transfusion and therapeutic injection is a non-billable ICD-10-CM category code (T80). |
| 7th character | The appropriate 7th character is to be added to each code from category T78 | The appropriate 7th character is to be added to each code from category T80 |
| Includes | Arthus reaction | complications following perfusion |
| Use additional code | — | code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5) code(s) to identify the specified condition resulting from the complication code to identify devices involved and details of circumstances (Y62-Y82) |
Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources