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A07.2 ICD-10-CM Code: Cryptosporidiosis

Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.

Coding at a Glance

Inpatient Payment Groups (MS-DRG)

Potential MS-DRG participation — not a DRG assignment.

MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v43, Appendix B.

  • MS-DRG 371 — MAJOR GASTROINTESTINAL DISORDERS AND PERITONEAL INFECTIONS WITH MCC (MDC 06)
  • MS-DRG 372 — MAJOR GASTROINTESTINAL DISORDERS AND PERITONEAL INFECTIONS WITH CC (MDC 06)
  • MS-DRG 373 — MAJOR GASTROINTESTINAL DISORDERS AND PERITONEAL INFECTIONS WITHOUT CC/MCC (MDC 06)

A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.

Risk Adjustment (CMS-HCC)

Payment categories this diagnosis maps to under CMS-HCC V28, payment year 2026.

  • HCC 6 — Opportunistic Infections

Other models: CMS-HCC V22 HCC 6 · RxHCC V08 HCC 5

Risk scores depend on the enrollee's full accepted diagnosis set and segment; a category mapping alone does not determine payment.

Code Overview

Cryptosporidiosis is a billable ICD-10-CM diagnosis code (A07.2).

MedCoder summary Summary composed by MedCoder from this code's official ICD-10-CM record. The tabular instructional notes themselves appear verbatim below.

Indexed Clinical Terms (4)

Official source data — entries quoted as published, in the Index’s own lookup phrasing

Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code. These are alphabetic-index entries shown as the Index writes them — lookup phrasing, not necessarily the wording of a final diagnosis.

Verify Before Coding

  • CC as a secondary diagnosis (FY2026). Can raise the stay's MS-DRG severity tier.

From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.

Relationships & Classification

MedCoder structured relationships — computed from published CMS and AHRQ datasets

Other codes that name A07.2 or its code family, from the CMS ICD-10-CM tabular instructional notes. Tabular-note edges are stored at the code family level that carries each note.

Referenced by 15 Excludes1 notes: A06 — Amebiasis (via A07.-), B50 — Plasmodium falciparum malaria (via A07.-), B50-B64 — Protozoal diseases (B50-B64) (via A07.-), B51 — Plasmodium vivax malaria (via A07.-), B52 — Plasmodium malariae malaria (via A07.-), B53 — Other specified malaria (via A07.-), B54 — Unspecified malaria (via A07.-), B55 — Leishmaniasis (via A07.-), B56 — African trypanosomiasis (via A07.-), B57 — Chagas' disease (via A07.-), B58 — Toxoplasmosis (via A07.-), B59 — Pneumocystosis (via A07.-), B60 — Other protozoal diseases, not elsewhere classified, B60 — Other protozoal diseases, not elsewhere classified (via A07.-), B64 — Unspecified protozoal disease (via A07.-).

These codes’ tabular lists mark this diagnosis as mutually exclusive — not reported together unless the conditions are documented as unrelated.

Referenced by 6 Excludes2 notes: P35 — Congenital viral diseases (via A07.-), P35-P39 — Infections specific to the perinatal period (P35-P39) (via A07.-), P36 — Bacterial sepsis of newborn (via A07.-), P37 — Other congenital infectious and parasitic diseases (via A07.-), P38 — Omphalitis of newborn (via A07.-), P39 — Other infections specific to the perinatal period (via A07.-).

These codes’ tabular lists name this diagnosis as distinct — both may be reported when both are documented.

MS-DRG Grouper Relationships (FY2026)

Potential MS-DRG participation — not a DRG assignment.

FY2026 MS-DRG: CC — Complication or Comorbidity. Reported as a secondary diagnosis, this code raises the stay's MS-DRG severity tier — except when the principal diagnosis is one of 67 clinically related codes on its CMS exclusion list.

Named in the grouper logic of 3 MS-DRGs: DRG 371 (MDC 06), DRG 372 (MDC 06), DRG 373 (MDC 06).

From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.

Clinical classification (AHRQ CCSR):DIG001 — Intestinal infection (default); INF009 — Parasitic, other specified and unspecified infections.

Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.

Related Codes

Same clinical process (MS-DRG)

Acts as CC — raises the severity of other admissions. CMS groups these diagnoses into one MS-DRG principal-diagnosis exclusion process — a CC/MCC on this list never raises severity when the principal diagnosis is also on it.

A04.72 — Enterocolitis due to Clostridium difficile, not specified as recurrent, A04.8 — Other specified bacterial intestinal infections, A04.9 — Bacterial intestinal infection, unspecified, A05.0 — Foodborne staphylococcal intoxication, A05.2 — Foodborne Clostridium perfringens [Clostridium welchii] intoxication, A06.0 — Acute amebic dysentery, A06.1 — Chronic intestinal amebiasis, A06.2 — Amebic nondysenteric colitis, A06.9 — Amebiasis, unspecified, A07.1 — Giardiasis [lambliasis], A07.3 — Isosporiasis, A07.4 — Cyclosporiasis, A07.8 — Other specified protozoal intestinal diseases, A07.9 — Protozoal intestinal disease, unspecified, A08.0 — Rotaviral enteritis, A08.11 — Acute gastroenteropathy due to Norwalk agent, A08.19 — Acute gastroenteropathy due to other small round viruses, A08.2 — Adenoviral enteritis, A08.31 — Calicivirus enteritis, A08.32 — Astrovirus enteritis, +46 more

Same CMS-HCC risk category (V28)

CMS maps these diagnoses to the same Hierarchical Condition Category (Opportunistic Infections) for risk-adjusted payment.

A31.0 — Pulmonary mycobacterial infection, A31.2 — Disseminated mycobacterium avium-intracellulare complex (DMAC), B25.0 — Cytomegaloviral pneumonitis, B25.1 — Cytomegaloviral hepatitis, B25.2 — Cytomegaloviral pancreatitis, B25.8 — Other cytomegaloviral diseases, B25.9 — Cytomegaloviral disease, unspecified, B37.1 — Pulmonary candidiasis, B37.7 — Candidal sepsis, B37.81 — Candidal esophagitis, B44.0 — Invasive pulmonary aspergillosis, B44.1 — Other pulmonary aspergillosis, B44.2 — Tonsillar aspergillosis, B44.7 — Disseminated aspergillosis, B44.89 — Other forms of aspergillosis, B44.9 — Aspergillosis, unspecified, B45.0 — Pulmonary cryptococcosis, B45.1 — Cerebral cryptococcosis, B45.2 — Cutaneous cryptococcosis, B45.3 — Osseous cryptococcosis, +16 more

Same clinical category (CCSR)

AHRQ's Clinical Classifications Software groups these diagnoses under the same clinical categories (Intestinal infection, Parasitic, other specified and unspecified infections).

A06.4 — Amebic liver abscess, A06.5 — Amebic lung abscess, A06.6 — Amebic brain abscess, A06.7 — Cutaneous amebiasis, A06.81 — Amebic cystitis, A06.82 — Other amebic genitourinary infections, A06.89 — Other amebic infections, A06.9 — Amebiasis, unspecified, A07.0 — Balantidiasis, A07.1 — Giardiasis [lambliasis], A07.3 — Isosporiasis, A07.4 — Cyclosporiasis, A07.8 — Other specified protozoal intestinal diseases, A07.9 — Protozoal intestinal disease, unspecified, A08.0 — Rotaviral enteritis, A08.11 — Acute gastroenteropathy due to Norwalk agent, A08.19 — Acute gastroenteropathy due to other small round viruses, A08.2 — Adenoviral enteritis, A08.31 — Calicivirus enteritis, A08.32 — Astrovirus enteritis, +278 more

Same Index main term, other category

The ICD-10-CM Index to Diseases and Injuries files this code under the main terms “Gastroenteritis”, “Diarrhea, diarrheal”, “Cryptosporidiosis”; these codes share that main term but sit in a different category of the Tabular List.

A04.4 — Other intestinal Escherichia coli infections (due to, Escherichia coli), A04.5 — Campylobacter enteritis (due to, Campylobacter), A04.6 — Enteritis due to Yersinia enterocolitica (due to, Yersinia enterocolitica), A04.71 — Enterocolitis due to Clostridium difficile, recurrent (due to, Clostridium difficile, recurrent), A04.72 — Enterocolitis due to Clostridium difficile, not specified as recurrent (due to, Clostridium difficile, not specified as recurrent), A04.8 — Other specified bacterial intestinal infections (due to, Staphylococcus), A04.9 — Bacterial intestinal infection, unspecified (due to, bacteria), A06.0 — Acute amebic dysentery (amebic), A06.1 — Chronic intestinal amebiasis (amebic, chronic), A06.2 — Amebic nondysenteric colitis (amebic, nondysenteric), A08.0 — Rotaviral enteritis (rotaviral), A08.11 — Acute gastroenteropathy due to Norwalk agent (viral NEC, Norwalk agent), A08.39 — Other viral enteritis (viral NEC, infantile), A08.4 — Viral intestinal infection, unspecified (viral NEC), A08.8 — Other specified intestinal infections (due to, specified organism NEC), A09 — Infectious gastroenteritis and colitis, unspecified (epidemic), A18.32 — Tuberculous enteritis (tuberculous), B49 — Unspecified mycosis (mycotic NEC), B65.2 — Schistosomiasis due to Schistosoma japonicum (due to, S. japonicum), B76.1 — Necatoriasis (due to, Necator americanus), +29 more

Lab tests where this diagnosis supports Medicare coverage (NCD)

Medicare's National Coverage Determination (NCD) program lists this diagnosis as medical justification for these lab tests.

Fecal Occult Blood Test (FOBT), HIV Screening Test, Iron Panel

Contextual Map

Every relationship of A07.2 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Run A07.2 with these 14 related codes in Claim Check

Hierarchy

Referenced by Excludes1 notes (15)

  • A06 — Amebiasis[Excludes1](via A07.-): “other protozoal intestinal diseases (A07.-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
  • B50 — Plasmodium falciparum malaria[Excludes1](via A07.-): “other protozoal intestinal diseases (A07.-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
  • B50-B64 — Protozoal diseases (B50-B64)[Excludes1](via A07.-): “other protozoal intestinal diseases (A07.-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
  • B51 — Plasmodium vivax malaria[Excludes1](via A07.-): “other protozoal intestinal diseases (A07.-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
  • B52 — Plasmodium malariae malaria[Excludes1](via A07.-): “other protozoal intestinal diseases (A07.-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
  • B53 — Other specified malaria[Excludes1](via A07.-): “other protozoal intestinal diseases (A07.-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
  • B54 — Unspecified malaria[Excludes1](via A07.-): “other protozoal intestinal diseases (A07.-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
  • B55 — Leishmaniasis[Excludes1](via A07.-): “other protozoal intestinal diseases (A07.-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
  • and 7 more

Referenced by Excludes2 notes

Clinical classification (CCSR)

Risk adjustment (CMS-HCC)

  • HCC 6 — Opportunistic Infections [CMS-HCC]— CMS-HCC V28 · 2026

MS-DRG Grouper

MDC crossing

  • MDC 06 — Diseases and Disorders of the Digestive System[MDC crossing]: “Diseases and Disorders of the Digestive System — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs. 5,744 same-MDC procedures group here; browse them on the MDC page.”— CMS MS-DRG Definitions Manual · FY2026

Index entries

  • Cryptosporidiosis[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
  • Diarrhea, diarrheal (disease) (infantile) (inflammatory), due to, Cryptosporidium[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
  • Gastroenteritis (acute) (chronic) (noninfectious), due to, Cryptosporidium[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
  • Infection, infected, infective (opportunistic), Cryptosporidium[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026

Nearest codes

Change history

  • FY2016 — In the code set at ICD-10-CM adoption [Change history]— CMS release files (code change ledger) · icd10cm-fy2016

Sources for this page

Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.

Code, title, tabular notes and index terms Official source data
CMS/CDC ICD-10-CM FY2026 tabular list, index and tables, effective October 1, 2025 Release, file and checksum · Publisher’s page
Claim edits Official source data
CMS Definitions of Medicare Code Edits — v43.1 (April 2026) Release, file and checksum · Publisher’s page
Inpatient payment groups Official source data
CMS MS-DRG Definitions Manual (incl. Appendix B diagnosis index, Appendix C CC/MCC list, Appendix E procedure index) and IPPS Final Rule tables — v43 Release, file and checksum · Publisher’s page
Risk adjustment Official source data
2026 Mid-Year Final ICD-10 Mappings + Model Software (cms.gov/files/zip/2026-midyear-final-icd-10-mappings.zip, 2026-midyear-final-model-software.zip) — CMS-HCC V28, PY2026 mid-year final release Release, file and checksum · Publisher’s page
Change history and date-of-service validity Official source data
CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page
Comparisons, relationships and the contextual map MedCoder structured relationship
Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears
Summary and FAQ answers MedCoder explanation
Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.

Labels on this page: Official source data · MedCoder structured relationship · MedCoder explanation. How to read the labels · All data sources and release dates

Cite this page

Reference this page in a research guide, syllabus or article. The release is included because code content changes each year.

MedCoder.ai. "A07.2 — Cryptosporidiosis." ICD-10-CM FY2026. https://medcoder.ai/icd10/code/a07.2-cryptosporidiosis

Change history

  • FY2016 — October 1, 2015
    In the code set at ICD-10-CM adoption
    Cryptosporidiosis

No changes since FY2016 — additions, deletions, description changes and billable-status changes are tracked through FY2027 (effective October 1, 2026), and none are recorded for this code. Note changes are tracked from FY2027 only.

Nearest Codes in This Family

Official ICD-10-CM classifications closest to A07.2 in its code family, with their registry titles.

View all codes in the A07 family