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B00.7 ICD-10-CM Code: Disseminated herpesviral disease

Compare with another codeCheck this code on a claim

Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.

Coding at a Glance

Tabular directives
1 inclusion term · 1 Excludes1 · 3 Excludes2
Risk adjustment
CMS-HCC V28: 1 category · CMS-HCC V22 category 2

Billable · FY2027A valid, specific ICD-10-CM code, reportable for dates of service in FY2027.

What you need to know

Source: CMS/NCHS Official ICD-10-CM tabular notes, quoted. From the CMS/NCHS tabular list for the release in force. A note the category or block publishes applies to this code too; the Instructions section marks which is which.

Excludes1Never report with this code
  • congenital herpesviral infections (P35.2)
Excludes2Not included here; may be reported together
  • anogenital herpesviral infection (A60.-)
  • gammaherpesviral mononucleosis (B27.0-)
  • herpangina (B08.5)
IncludesWhat this code covers
  • Herpesviral sepsis

Most relevant related codes MedCoder-derived

Read off the official notes above and this code’s own position in the tabular list. Which to report is a documentation question; Compare shows the two side by side.

CompareCheck ClaimView Related Codes

Inpatient Payment Groups (MS-DRG)

Potential MS-DRG participation — not a DRG assignment.

MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v44, Appendix B.

  • MS-DRG 791 — PREMATURITY WITH MAJOR PROBLEMS (MDC 15)
  • MS-DRG 793 — FULL TERM NEONATE WITH MAJOR PROBLEMS (MDC 15)
  • MS-DRG 870 — SEPTICEMIA OR SEVERE SEPSIS WITH MV >96 HOURS (MDC 18)
  • MS-DRG 871 — SEPTICEMIA OR SEVERE SEPSIS WITHOUT MV >96 HOURS WITH MCC (MDC 18)
  • MS-DRG 872 — SEPTICEMIA OR SEVERE SEPSIS WITHOUT MV >96 HOURS WITHOUT MCC (MDC 18)
  • MS-DRG 974 — HIV WITH MAJOR RELATED CONDITION WITH MCC (MDC 25)
  • MS-DRG 975 — HIV WITH MAJOR RELATED CONDITION WITH CC (MDC 25)
  • MS-DRG 976 — HIV WITH MAJOR RELATED CONDITION WITHOUT CC/MCC (MDC 25)

A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.

Risk Adjustment (CMS-HCC)

Payment categories this diagnosis maps to under CMS-HCC V28, payment year 2026.

  • HCC 2 — Septicemia, Sepsis, Systemic Inflammatory Response Syndrome/Shock

Other models: CMS-HCC V22 HCC 2

Risk scores depend on the enrollee's full accepted diagnosis set and segment; a category mapping alone does not determine payment.

Coding instructions

Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for B00.7 in the official ICD-10-CM tabular list, quoted as published.

Source: CMS/CDC — ICD-10-CM Tabular ListRelease: FY2027Effective: October 1, 2026

Trace:FY2027 changesChange historyRelease, file and checksum

Notes without a marker are published on B00.7 itself; “inherited from” names the category or block whose note applies here.

Inclusion Terms

Alternative terms the tabular list files under this code.

  • Herpesviral sepsis

Excludes1 — Not Coded Here

Conditions generally not reported together with this code (Excludes1) -- an error unless the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Source: inherited from B00

Excludes2 — Not Included Here

Conditions not covered by this code, but which may be reported alongside it when both are present.

Source: inherited from B00

Coder workflow for B00.7

MedCoder structured workflow — derived from this code’s own official record

Before you code B00.7

  1. Check the Excludes1 note: if the documentation supports a condition named there, do not simply proceed with B00.7. Excludes1 conditions are not reported together with this code unless the record shows they are unrelated (Guidelines I.A.12.a).

    See the official tabular notes

Choose the right path

  1. Does the documentation support a condition named in B00.7’s Excludes1 note?
    Yes → Do not simply proceed: review the excluded code. Both are reported only when the record shows the two conditions are unrelated.
    No → Continue.

    ReviewP35.2

Consider B00.7. Then confirm the code is valid for the date of service in the Verify section.

Documentation check

The provider’s diagnostic statement
Codes are assigned from the provider’s documented diagnosis, not from clinical criteria, test values or a medication list (Guidelines I.A.19).

Official instructions as workflow

  • Excludes1 — check before selecting B00.7(1 note)

    Coding workflow: If the documentation supports a condition named in this note, do not simply proceed with B00.7: the two are not reported together. The one exception is when the record shows the two conditions are unrelated to each other.

    CompareP35.2

    See the official tabular notes · Guidelines I.A.12.a

  • Excludes2 — not part of B00.7(3 notes)

    Coding workflow: The conditions named in this note are not included in B00.7. When the record documents both, both may be reported; the note is a boundary, not a prohibition.

    CompareA60, B27.0, B08.5

    See the official tabular notes · Guidelines I.A.12.b

Coding decision scenarios

Pattern scenarios for this code’s structure — decision rules, not clinical cases

Documentation: Both the condition B00.7 describes and a condition named in its Excludes1 note are documented for the same encounter.

Coding question: Can both codes be reported?

Path: Review the Excludes1 note and the excluded code, and look for a provider statement on whether the two conditions are related.

Reason: Excludes1 means the two are not coded together; the exception is when the record shows the conditions are unrelated to each other (Guidelines I.A.12.a).

ReviewP35.2

Every row is derived from this code’s own record — its title, tabular notes, 7th-character family and same-category siblings — with fixed MedCoder wording; nothing is inferred about a patient. The official notes and guideline text are in the sections each row links to, and they control.

Don’t confuse B00.7 with…

MedCoder analysis — pairs from this code’s official notes, distinctions written by MedCoder

The codes most likely to be picked instead of B00.7 — named in its own official notes, or sharing its laterality or encounter family — with what separates them and which documentation moves the case. Each links to the full comparison.

  • P35.2— Excludes1 conflict (Excludes1 — generally not reported together)

    Not coded here — the tabular list excludes this pair for the same encounter.

    Not reported together with this code, except where the two conditions are documented as unrelated.

    What moves you there: Documentation of congenital herpesviral infections moves the case to P35.2; the two are not reported together unless documented as unrelated.

    Full comparison: B00.7 vs P35.2 →

  • B00.9— Specificity relationship (Review)

    Overlapping diagnoses in the same category.

    Overlapping codes in the same category — the documentation decides which is the more specific fit.

    What moves you there: A record that documents no more than “Herpesviral infection, unspecified” takes B00.9; specificity in the record moves it back here.

    Full comparison: B00.7 vs B00.9 →

  • A60— Excludes2 relationship (Informational)

    Distinct conditions — both may be reported.

    A distinct condition — both may be reported when both are documented.

    What moves you there: Documentation of anogenital herpesviral infection adds A60; it is not part of this code and both may be reported when both are documented.

    Full comparison: B00.7 vs A60 →

  • B27.0— Excludes2 relationship (Informational)

    Distinct conditions — both may be reported.

    A distinct condition — both may be reported when both are documented.

    What moves you there: Documentation of gammaherpesviral mononucleosis adds B27.0; it is not part of this code and both may be reported when both are documented.

    Full comparison: B00.7 vs B27.0 →

  • B08.5— Excludes2 relationship (Informational)

    Distinct conditions — both may be reported.

    A distinct condition — both may be reported when both are documented.

    What moves you there: Documentation of herpangina adds B08.5; it is not part of this code and both may be reported when both are documented.

    Full comparison: B00.7 vs B08.5 →

Relationships are read from this code's own official notes, its laterality siblings and its encounter family; the wording of each distinction is MedCoder editorial, and the documentation named in each “what moves you there” line is the official note phrase or sibling title itself. Source: CMS ICD-10-CM tabular instructional notes; ICD-10-CM Official Guidelines, Section I.A.12.a.

Coding context

Guidelines, coding notes, decision aids, relationships (with MS-DRG and CCSR classification), hierarchy, HCC, coverage and the context map: what a coder reaches for after the core. Each section names whether it is official source data, a MedCoder-derived relationship or MedCoder editorial.

Code Overview

Disseminated herpesviral disease is a billable ICD-10-CM diagnosis code (B00.7).

MedCoder summary Summary composed by MedCoder from this code's official ICD-10-CM record. The tabular instructional notes themselves appear verbatim below.

Verify Before Coding

  • MCC as a secondary diagnosis (FY2027). Can raise the stay's MS-DRG severity tier.

From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.

Relationships & Classification

MedCoder-derived relationships — computed from published CMS and AHRQ datasets

Other codes that name B00.7 or its code family, from the CMS ICD-10-CM tabular instructional notes. Tabular-note edges are stored at the code family level that carries each note.

Referenced by 2 Excludes2 notes: A41 — Other sepsis, B10 — Other human herpesviruses (via B00.-).

These codes’ tabular lists name this diagnosis as distinct — both may be reported when both are documented.

Referenced by 1 Code First instruction: H67 — Otitis media in diseases classified elsewhere (via B00.-).

Each of these codes carries a Code First note naming this condition — when that code is reported, THIS code is sequenced first, ahead of it.

Referenced by 1 Code Also instruction: D81.82 — Activated Phosphoinositide 3-kinase Delta Syndrome [APDS] (via B00.-).

These codes suggest coding this condition alongside when both are present.

MS-DRG Grouper Relationships (FY2027)

Potential MS-DRG participation — not a DRG assignment.

FY2027 MS-DRG: MCC — Major Complication or Comorbidity. Reported as a secondary diagnosis, this code raises the stay's MS-DRG severity tier — except when the principal diagnosis is one of 41 clinically related codes on its CMS exclusion list. Does not count toward severity when the stay groups to DRGs 974-976 (HIV with Major Related Condition).

Named in the grouper logic of 8 MS-DRGs: DRG 791 (MDC 15), DRG 793 (MDC 15), DRG 870 (MDC 18), DRG 871 (MDC 18), DRG 872 (MDC 18), DRG 974 (MDC 25), DRG 975 (MDC 25), DRG 976 (MDC 25).

From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.

Clinical classification (AHRQ CCSR):INF008 — Viral infection (default).

Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.

Related Codes

Same clinical process (MS-DRG)

Acts as MCC — raises the severity of other admissions. CMS groups these diagnoses into one MS-DRG principal-diagnosis exclusion process — a CC/MCC on this list never raises severity when the principal diagnosis is also on it.

A41.51 — Sepsis due to Escherichia coli [E. coli], A41.52 — Sepsis due to Pseudomonas, A41.53 — Sepsis due to Serratia, A41.54 — Sepsis due to Acinetobacter baumannii, A41.59 — Other Gram-negative sepsis, A41.81 — Sepsis due to Enterococcus, A41.89 — Other specified sepsis, A41.9 — Sepsis, unspecified organism, A42.7 — Actinomycotic sepsis, A54.86 — Gonococcal sepsis, B00.82 — Herpes simplex myelitis, B00.89 — Other herpesviral infection, B00.9 — Herpesviral infection, unspecified, B10.81 — Human herpesvirus 6 infection, B10.82 — Human herpesvirus 7 infection, B10.89 — Other human herpesvirus infection, B37.7 — Candidal sepsis, B92 — Sequelae of leprosy, B94.2 — Sequelae of viral hepatitis, B94.8 — Sequelae of other specified infectious and parasitic diseases, +20 more

Same CMS-HCC risk category (V28)

CMS maps these diagnoses to the same Hierarchical Condition Category (Septicemia, Sepsis, Systemic Inflammatory Response Syndrome/Shock) for risk-adjusted payment.

A41.52 — Sepsis due to Pseudomonas, A41.53 — Sepsis due to Serratia, A41.54 — Sepsis due to Acinetobacter baumannii, A41.59 — Other Gram-negative sepsis, A41.81 — Sepsis due to Enterococcus, A41.89 — Other specified sepsis, A41.9 — Sepsis, unspecified organism, A42.7 — Actinomycotic sepsis, A48.3 — Toxic shock syndrome, A54.86 — Gonococcal sepsis, B37.7 — Candidal sepsis, M35.81 — Multisystem inflammatory syndrome, P02.70 — Newborn affected by fetal inflammatory response syndrome, P36.0 — Sepsis of newborn due to streptococcus, group B, P36.10 — Sepsis of newborn due to unspecified streptococci, P36.19 — Sepsis of newborn due to other streptococci, P36.2 — Sepsis of newborn due to Staphylococcus aureus, P36.30 — Sepsis of newborn due to unspecified staphylococci, P36.39 — Sepsis of newborn due to other staphylococci, P36.4 — Sepsis of newborn due to Escherichia coli, +31 more

Same clinical category (CCSR)

AHRQ's Clinical Classifications Software groups these diagnoses under the same clinical category (Viral infection).

+309 more

Same Index main term, other category

The ICD-10-CM Index to Diseases and Injuries files this code under the main terms “Herpes, herpesvirus, herpetic”, “Sepsis”; these codes share that main term but sit in a different category of the Tabular List.

A42.7 — Actinomycotic sepsis (actinomycotic), A54.86 — Gonococcal sepsis (gonococcal), A60.00 — Herpesviral infection of urogenital system, unspecified (genital, genitalis), A60.01 — Herpesviral infection of penis (penis), A60.02 — Herpesviral infection of other male genital organs (scrotum), A60.03 — Herpesviral cervicitis (anogenital, urogenital tract, cervix), A60.04 — Herpesviral vulvovaginitis (vulva), A60.09 — Herpesviral infection of other urogenital tract (genital, genitalis, female), A60.1 — Herpesviral infection of perianal skin and rectum (rectum), A60.9 — Anogenital herpesviral infection, unspecified (anogenital), B02.0 — Zoster encephalitis (zoster, encephalitis), B02.1 — Zoster meningitis (zoster, meningitis), B02.21 — Postherpetic geniculate ganglionitis (zoster, oticus), B02.22 — Postherpetic trigeminal neuralgia (zoster, trigeminal neuralgia), B02.23 — Postherpetic polyneuropathy (zoster, polyneuropathy), B02.24 — Postherpetic myelitis (zoster, myelitis), B02.29 — Other postherpetic nervous system involvement (zoster, neuritis, neuralgia), B02.30 — Zoster ocular disease, unspecified (eye), B02.31 — Zoster conjunctivitis (conjunctivitis, zoster), B02.32 — Zoster iridocyclitis (iridocyclitis, zoster), +92 more

Lab tests where this diagnosis supports Medicare coverage (NCD)

Medicare's National Coverage Determination (NCD) program lists this diagnosis as medical justification for these lab tests.

Gamma-glutamyl Transferase (GGT) Test, HIV Screening Test

Contextual Map

Every relationship of B00.7 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Run B00.7 with these 4 related codes in Claim Check

Hierarchy

Referenced by Excludes2 notes

  • A41 — Other sepsis[Excludes2]: “sepsis (due to) (in) herpesviral (B00.7)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2027
  • B10 — Other human herpesviruses[Excludes2](via B00.-): “herpes simplex (B00.-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2027

Referenced by Code First instructions

Referenced by Code Also instructions

Clinical classification (CCSR)

Risk adjustment (CMS-HCC)

  • HCC 2 — Septicemia, Sepsis, Systemic Inflammatory Response Syndrome/Shock [CMS-HCC]— CMS-HCC V28 · 2026

MS-DRG Grouper

MDC crossing

  • MDC 15 — Newborns and Other Neonates with Conditions Originating in Perinatal Period[MDC crossing]: “Newborns and Other Neonates with Conditions Originating in Perinatal Period — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs.”— CMS MS-DRG Definitions Manual · FY2027
  • MDC 18 — Infectious and Parasitic Diseases, Systemic or Unspecified Sites[MDC crossing]: “Infectious and Parasitic Diseases, Systemic or Unspecified Sites — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs. 1 same-MDC procedures group here; browse them on the MDC page.”— CMS MS-DRG Definitions Manual · FY2027

Index entries

  • Disease, diseased, herpesviral, disseminated[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2027
  • Herpes, herpesvirus, herpetic, sepsis[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2027
  • Infection, infected, infective (opportunistic), herpes (simplex), disseminated[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2027
  • Sepsis (generalized) (unspecified organism), herpesviral[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2027

Nearest codes (17)

Change history

  • FY2016 — In the code set at ICD-10-CM adoption [Change history]— CMS release files (code change ledger) · icd10cm-fy2016

Reference

Index terms and tables, published questions and FAQ, every source behind this page with its release and checksum, the date-of-service check and the complete change history.

Indexed Clinical Terms (4)

Official source data — entries quoted as published, in the Index’s own lookup phrasing

Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code. These are alphabetic-index entries shown as the Index writes them — lookup phrasing, not necessarily the wording of a final diagnosis.

Sources for this page

Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.

Code, title, tabular notes and index terms Official source data
CMS/CDC ICD-10-CM FY2027 tabular list, index and tables, effective October 1, 2026 Release, file and checksum · Publisher’s page
Claim edits Official source data
CMS Definitions of Medicare Code Edits — v44.0 (October 2026) Release, file and checksum · Publisher’s page
Inpatient payment groups Official source data
CMS MS-DRG Definitions Manual (incl. Appendix B diagnosis index, Appendix C CC/MCC list, Appendix E procedure index) and IPPS Final Rule tables — v44 Release, file and checksum · Publisher’s page
Risk adjustment Official source data
2026 Mid-Year Final ICD-10 Mappings + Model Software (cms.gov/files/zip/2026-midyear-final-icd-10-mappings.zip, 2026-midyear-final-model-software.zip) — CMS-HCC V28, PY2026 mid-year final release Release, file and checksum · Publisher’s page
Change history and date-of-service validity Official source data
CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page
Comparisons, relationships and the contextual map MedCoder-derived relationship
Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears
Summary and FAQ answers MedCoder editorial explanation
Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.

Current data releases:ICD-10-CM FY2027 · ICD-10-PCS FY2027 · HCPCS October 2026 · MS-DRG v44 · Medicare Code Editor v44.0 · NCCI PTP Q4 2026 · MUE Q4 2026 · NCD code lists 2026-01 · LCD export September 28, 2026 · All releases and sources

Labels on this page: Official source data · MedCoder-derived relationship · MedCoder editorial explanation. How to read the labels · All data sources and release dates · CMS coding rules

Cite this page

Reference this page in a research guide, syllabus or article. The release is included because code content changes each year.

MedCoder.ai. "B00.7 — Disseminated herpesviral disease." ICD-10-CM FY2027. https://medcoder.ai/icd10/code/b00.7-disseminated-herpesviral-disease

Change history

  • FY2016 — October 1, 2015
    In the code set at ICD-10-CM adoption
    Disseminated herpesviral disease

No changes since FY2016 — additions, deletions, description changes and billable-status changes are tracked through FY2027, and none are recorded for this code. Note changes are tracked from FY2027 only.

Nearest Codes in This Family

Official ICD-10-CM classifications closest to B00.7 in its code family, with their registry titles.

View all codes in the B00 family