C96.2 ICD-10-CM Code: Malignant mast cell neoplasm
Compare with another code for C96.2Check this code on a claim
Billing Status: NO. This is a non-billable ICD-10-CM code: report a more specific billable code beneath it.
Coding at a Glance
- Official instructions
- 4 Excludes1 · 4 Excludes2
Not billable · FY2027A non-billable heading in the tabular list: report a more specific code beneath it.
What you need to know
Source: CMS/NCHS Official ICD-10-CM tabular notes, quoted. From the CMS/NCHS tabular list for the release in force. A note the category or block publishes applies to this code too, and is marked with where it comes from.
- Excludes1Not reported with this code unless documented as unrelated
Where it sits Source: CMS/NCHS
Under:Chapter 2: NeoplasmsC00-C96 Malignant neoplasmsC81-C96 Malignant neoplasms of lymphoid, hematopoietic and related tissueC96 Other and unspecified malignant neoplasms of lymphoid, hematopoietic and related tissue
Codes under C96.2 (4)
Most relevant related codes MedCoder-derived
Read off the official notes above and this code’s own position in the tabular list. Which to report is a documentation question; Compare shows the two side by side.
Coding instructions
Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for C96.2 in the official ICD-10-CM tabular list, quoted as published.
Source: CMS/CDC — ICD-10-CM Tabular ListRelease: FY2027Effective: October 1, 2026
Trace:FY2027 changesChange historyRelease, file and checksum
Notes without a marker are published on C96.2 itself; “inherited from” names the category or block whose note applies here.
Excludes1 — Not Coded Here
Conditions generally not reported together with this code (Excludes1) -- an error unless the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
- indolent mastocytosis (D47.02) Compare C96.2 vs D47.02 →
- mast cell leukemia (C94.30) Compare C96.2 vs C94.30 →
- mastocytosis (congenital) (cutaneous) (Q82.2) Compare C96.2 vs Q82.2 →
- personal history of other malignant neoplasms of lymphoid, hematopoietic and related tissues (Z85.79) inherited from C96Compare C96.2 vs Z85.79 →
Excludes2 — Not Included Here
Conditions not covered by this code, but which may be reported alongside it when both are present.
- Kaposi's sarcoma of lymph nodes (C46.3) Compare C96.2 vs C46.3 →
- secondary and unspecified neoplasm of lymph nodes (C77.-) Compare C96.2 vs C77 →
- secondary neoplasm of bone marrow (C79.52) Compare C96.2 vs C79.52 →
- secondary neoplasm of spleen (C78.89) Compare C96.2 vs C78.89 →
Source: inherited from C81-C96
Coder workflow for C96.2
MedCoder structured workflow — derived from this code’s own official record
Before you code C96.2
- C96.2 is not reportable as written. Select the more specific code beneath it that the documentation supports. Codes are reported to the highest level of specificity the classification provides (Guidelines I.B.2).
ReviewC96.20, C96.21, C96.22, C96.29
See the relationships section · Guide: How to choose an ICD-10-CM code →
- Confirm the documented site and behavior (this code’s block classifies malignant neoplasms), whether the site is primary or secondary, and whether the malignancy is current or a personal history: a previously excised malignancy with no further treatment and no evidence of disease is history, not current disease. Verify the site against the Table of Neoplasms. Neoplasm chapter guidelines (Guidelines I.C.2.a, I.C.2.d, I.C.2.m).
See the Table of Neoplasms entries · Guide: Active cancer vs history of cancer →
- Check the Excludes1 note: if the documentation supports a condition named there, do not simply proceed with the code beneath C96.2. Excludes1 conditions are not reported together with this code unless the record shows they are unrelated (Guidelines I.A.12.a).
Choose the right path
- Does the documentation support one of the more specific codes beneath C96.2?
Yes → Select that code and continue the checks below on its own page.
No → C96.2 cannot be reported as written. Where the codes beneath it include an unspecified code, that code applies when the record goes no further; otherwise query for the missing detail. - Does the documentation support a condition named in C96.2’s Excludes1 note?
Yes → Do not simply proceed: review the excluded code. Both are reported only when the record shows the two conditions are unrelated.
No → Continue.
Report the code beneath C96.2 that the documentation supports, not C96.2 itself. Then confirm that code is valid for the date of service on its own page.
Documentation check
- The provider’s diagnostic statement
- Codes are assigned from the provider’s documented diagnosis, not from clinical criteria, test values or a medication list (Guidelines I.A.19).
- Anatomical site
- At the most specific level the record states; a site the classification separates cannot be assumed from a procedure or a measurement.
- Behavior and current-versus-history status
- Malignant, in situ, benign or uncertain; primary or secondary; current disease or personal history (Guidelines I.C.2.m).
Official instructions as workflow
Excludes1 — check before selecting C96.2(4 notes)
Coding workflow: If the documentation supports a condition named in this note, do not simply proceed with C96.2: the two are not reported together. The one exception is when the record shows the two conditions are unrelated to each other.
CompareD47.02, C94.30, Q82.2, Z85.79
See the official tabular notes · Guidelines I.A.12.a
Excludes2 — not part of C96.2(4 notes)
Coding workflow: The conditions named in this note are not included in C96.2. When the record documents both, both may be reported; the note is a boundary, not a prohibition.
CompareC46.3, C77, C79.52, C78.89
See the official tabular notes · Guidelines I.A.12.b
Coding decision scenarios
Pattern scenarios for this code’s structure — decision rules, not clinical cases
Documentation: Both the condition C96.2 describes and a condition named in its Excludes1 note are documented for the same encounter.
Coding question: Can both codes be reported?
Path: Review the Excludes1 note and the excluded code, and look for a provider statement on whether the two conditions are related.
Reason: Excludes1 means the two are not coded together; the exception is when the record shows the conditions are unrelated to each other (Guidelines I.A.12.a).
Every row is derived from this code’s own record — its title, tabular notes, 7th-character family and same-category siblings — with fixed MedCoder wording; nothing is inferred about a patient. The official notes and guideline text are in the sections each row links to, and they control.
Coding context
Guidelines, coding notes, decision aids, relationships (with MS-DRG and CCSR classification), hierarchy, HCC, coverage and the context map: what a coder reaches for after the core. Each section names whether it is official source data, a MedCoder-derived relationship or MedCoder editorial.
Code Overview
MedCoder summary Summary composed by MedCoder from this code's official ICD-10-CM record. The tabular instructional notes themselves appear verbatim below.
Verify Before Coding
From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.
Relationships & Classification
MedCoder-derived relationships — computed from published CMS and AHRQ datasets
Other codes that name C96.2 or its code family, from the CMS ICD-10-CM tabular instructional notes. Tabular-note edges are stored at the code family level that carries each note.
Referenced by 5 Excludes1 notes across 3 chapters: C76 — Malignant neoplasm of other and ill-defined sites (via C96.-), C77 — Secondary and unspecified malignant neoplasm of lymph nodes (via C96.-), D47.0 — Mast cell neoplasms of uncertain behavior, D89.4 — Mast cell activation syndrome and related disorders, Q82.2 — Congenital cutaneous mastocytosis.
These codes’ tabular lists mark this diagnosis as mutually exclusive — not reported together unless the conditions are documented as unrelated.
Referenced by 2 Code First instructions across 2 chapters: N16 — Renal tubulo-interstitial disorders in diseases classified elsewhere, Z15.0 — Genetic susceptibility to malignant neoplasm (via C96.-).
Each of these codes carries a Code First note naming this condition — when that code is reported, THIS code is sequenced first, ahead of it.
Clinical classification (AHRQ CCSR):NEO058 — Non-Hodgkin lymphoma (default).
Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.
Related Codes
Same clinical category (CCSR)
AHRQ's Clinical Classifications Software groups these diagnoses under the same clinical category (Non-Hodgkin lymphoma).
Contextual Map
Every relationship of C96.2 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.
Run C96.2 with these 9 related codes in Claim Check
Hierarchy
- C00-D49 — Chapter 2: Neoplasms (C00-D49) (C00-D49)[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2027
- C81-C96 — Malignant neoplasms of lymphoid, hematopoietic and related tissue[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2027
Excludes1
- C94.30 — Mast cell leukemia not having achieved remission[Excludes1]: “mast cell leukemia (C94.30)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2027
- D47.02 — Systemic mastocytosis[Excludes1]: “indolent mastocytosis (D47.02)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2027
- Q82.2 — Congenital cutaneous mastocytosis[Excludes1]: “mastocytosis (congenital) (cutaneous) (Q82.2)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2027
Referenced by Excludes1 notes
- C76 — Malignant neoplasm of other and ill-defined sites[Excludes1](via C96.-): “malignant neoplasm of lymphoid, hematopoietic and related tissue (C81-C96)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2027
- C77 — Secondary and unspecified malignant neoplasm of lymph nodes[Excludes1](via C96.-): “malignant neoplasm of lymph nodes, specified as primary (C81-C86, C88, C96.-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2027
- D47.0 — Mast cell neoplasms of uncertain behavior[Excludes1]: “malignant mast cell neoplasm (C96.2-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2027
- D89.4 — Mast cell activation syndrome and related disorders[Excludes1]: “malignant mast cell neoplasm (C96.2-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2027
- Q82.2 — Congenital cutaneous mastocytosis[Excludes1]: “malignant mastocytosis (C96.2-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2027
Referenced by Code First instructions
- N16 — Renal tubulo-interstitial disorders in diseases classified elsewhere[Code First]: “lymphoma (C81.0-C85.9, C96.0-C96.9)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2027
- Z15.0 — Genetic susceptibility to malignant neoplasm[Code First](via C96.-): “, if applicable, any current malignant neoplasm (C00-C75, C81-C96)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2027
Clinical classification (CCSR)
- NEO058 — Non-Hodgkin lymphoma[CCSR]— AHRQ CCSR for ICD-10-CM Diagnoses (HCUP)
Nearest codes (12)
- C96 — Other and unspecified malignant neoplasms of lymphoid, hematopoietic and related tissue[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2027
- C96.0 — Multifocal and multisystemic (disseminated) Langerhans-cell histiocytosis[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2027
- C96.20 — Malignant mast cell neoplasm, unspecified[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2027
- C96.21 — Aggressive systemic mastocytosis[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2027
- C96.22 — Mast cell sarcoma[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2027
- C96.29 — Other malignant mast cell neoplasm[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2027
- C96.4 — Sarcoma of dendritic cells (accessory cells)[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2027
- C96.5 — Multifocal and unisystemic Langerhans-cell histiocytosis[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2027
- and 4 more
Change history (4)
- FY2018 — Became a non-billable header[Change history]— CMS release files (code change ledger) · icd10cm-fy2018
- and 3 more
Reference
Index terms and tables, published questions and FAQ, every source behind this page with its release and checksum, the date-of-service check and the complete change history.
Common coding questions
MedCoder editorial
Can C96.2 be billed directly?
No. C96.2 (Malignant mast cell neoplasm) is a non-billable ICD-10-CM category code. A more specific billable subcode must be selected based on clinical documentation.
Sources for this page
Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.
- Code, title, tabular notes and index terms Official source data
- CMS/CDC ICD-10-CM FY2027 tabular list, index and tables, effective October 1, 2026 Release, file and checksum · Publisher’s page
- Claim edits Official source data
- CMS Definitions of Medicare Code Edits — v44.0 (October 2026) Release, file and checksum · Publisher’s page
- Change history and date-of-service validity Official source data
- CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page
- Comparisons, relationships and the contextual map MedCoder-derived relationship
- Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears
- Summary and FAQ answers MedCoder editorial explanation
- Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.
Current data releases:ICD-10-CM FY2027 · ICD-10-PCS FY2027 · HCPCS October 2026 · MS-DRG v44 · Medicare Code Editor v44.0 · NCCI PTP Q4 2026 · MUE Q4 2026 · NCD code lists 2026-01 · LCD export September 28, 2026 · All releases and sources
Labels on this page: Official source data · MedCoder-derived relationship · MedCoder editorial explanation. How to read the labels · All data sources and release dates · CMS coding rules
Cite this page
Reference this page in a research guide, syllabus or article. The release is included because code content changes each year.
MedCoder.ai. "C96.2 — Malignant mast cell neoplasm." ICD-10-CM FY2027. https://medcoder.ai/icd10/code/c96.2-malignant-mast-cell-neoplasm
Change history
- FY2018 — October 1, 2017Became a non-billable headerFY2018 changes
- FY2018 — October 1, 2017Description revisedMalignant mast cell tumor → Malignant mast cell neoplasmFY2018 changes
- FY2018 — October 1, 2017Short description revisedMalignant mast cell tumor → Malignant mast cell neoplasmFY2018 changes
- FY2016 — October 1, 2015In the code set at ICD-10-CM adoptionMalignant mast cell tumor
Nearest Codes in This Family
Official ICD-10-CM classifications closest to C96.2 in its code family, with their registry titles.
- C96 — Other and unspecified malignant neoplasms of lymphoid, hematopoietic and related tissue
- C96.0 — Multifocal and multisystemic (disseminated) Langerhans-cell histiocytosis
- C96.20 — Malignant mast cell neoplasm, unspecified
- C96.21 — Aggressive systemic mastocytosis
- C96.22 — Mast cell sarcoma
- C96.29 — Other malignant mast cell neoplasm
- C96.4 — Sarcoma of dendritic cells (accessory cells)
- C96.5 — Multifocal and unisystemic Langerhans-cell histiocytosis
- C96.6 — Unifocal Langerhans-cell histiocytosis
- C96.9 — Malignant neoplasm of lymphoid, hematopoietic and related tissue, unspecified