D72.18 ICD-10-CM Code: Eosinophilia in diseases classified elsewhere
Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.
Inpatient Payment Groups (MS-DRG)
MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v43.0, Appendix B.
- MS-DRG 814 — RETICULOENDOTHELIAL AND IMMUNITY DISORDERS WITH MCC (MDC 16)
- MS-DRG 815 — RETICULOENDOTHELIAL AND IMMUNITY DISORDERS WITH CC (MDC 16)
- MS-DRG 816 — RETICULOENDOTHELIAL AND IMMUNITY DISORDERS WITHOUT CC/MCC (MDC 16)
A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.
Official Registry Overview & Definition
Official Tabular Instructional Notes
Sequencing, inclusion, and exclusion notes published for D72.18 in the official ICD-10-CM tabular list.
Excludes1 — Not Coded Here
Conditions generally not reported together with this code (Excludes1) -- an error unless the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
- basophilia (D72.824) Compare D72.18 vs D72.824 →
- immunity disorders (D80-D89) Compare D72.18 vs D80 →
- preleukemia (syndrome) (D46.9) Compare D72.18 vs D46.9 →
Excludes2 — Not Included Here
Conditions not covered by this code, but which may be reported alongside it when both are present.
- Löffler's syndrome (J82.89) Compare D72.18 vs J82.89 →
- pulmonary eosinophilia (J82.-) Compare D72.18 vs J82 →
- neutropenia (D70) Compare D72.18 vs D70 →
Code First
Underlying conditions that must be sequenced before this code.
- underlying disease, such as:
- chronic myelomonocytic leukemia (C93.1-)
Indexed Clinical Terms (1)
Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code.
- Eosinophilia (allergic) (idiopathic) (secondary), in disease classified elsewhere
Frequently Compared Codes
The official Excludes notes on D72.18 name these codes. Each comparison page covers when the two can — or must not — be reported together.
Change history
- FY2021 — 2020-10-01Added to the code setEosinophilia in diseases classified elsewhereFY2021 changes
Verify Before Coding
- Principal-diagnosis restriction. This is a manifestation code: the Medicare Code Editor requires the underlying condition (etiology) to be sequenced first, with this code reported after it.
From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim.
Referenced by Other Codes
Clinical classification (AHRQ CCSR):BLD007 — Diseases of white blood cells.
Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.
Potential MS-DRG Relationships (FY2026)
Not on the CMS CC/MCC list — as a secondary diagnosis this code does not change MS-DRG severity.
Named in the grouper logic of 3 MS-DRGs: DRG 814 (MDC 16), DRG 815 (MDC 16), DRG 816 (MDC 16).
From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.
Official ICD-10-CM tabular notes on other codes that name D72.18 or its code family.
Contextual Map
Every relationship of D72.18 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.
Hierarchy
- D50-D89 — Chapter 3: Diseases of the Blood and Blood-forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89) (D50-D89) [Hierarchy]
Code First
- C93.1 — Chronic myelomonocytic leukemia [Code First]: “chronic myelomonocytic leukemia (C93.1-)” · check together
Referenced by Code Also instructions
- C93.1 — Chronic myelomonocytic leukemia [Code Also]: “, if applicable, eosinophilia (D72.18)” · check together
- C94.8 — Other specified leukemias [Code Also]: “, if applicable, eosinophilia (D72.18)” · check together
Clinical classification (CCSR)
- BLD007 — Diseases of white blood cells [CCSR]
Potential MS-DRG
- DRG 814 — RETICULOENDOTHELIAL AND IMMUNITY DISORDERS WITH MCC [MS-DRG]: “RETICULOENDOTHELIAL AND IMMUNITY DISORDERS WITH MCC (MDC 16)”
- DRG 815 — RETICULOENDOTHELIAL AND IMMUNITY DISORDERS WITH CC [MS-DRG]: “RETICULOENDOTHELIAL AND IMMUNITY DISORDERS WITH CC (MDC 16)”
- DRG 816 — RETICULOENDOTHELIAL AND IMMUNITY DISORDERS WITHOUT CC/MCC [MS-DRG]: “RETICULOENDOTHELIAL AND IMMUNITY DISORDERS WITHOUT CC/MCC (MDC 16)”
MDC crossing · procedures (1614)
- MDC 16 — Diseases and Disorders of Blood, Blood Forming Organs and Immunologic Disorders [MDC crossing]: “Diseases and Disorders of Blood, Blood Forming Organs and Immunologic Disorders — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs.”
- 02HV02Z — Insertion of Monitoring Device into Superior Vena Cava, Open Approach [Same-MDC procedure]: “Insertion of Monitoring Device into Superior Vena Cava, Open Approach — grouped in MDC 16, the procedure side of this code's crossing.” · check together
- 02HV0DZ — Insertion of Intraluminal Device into Superior Vena Cava, Open Approach [Same-MDC procedure]: “Insertion of Intraluminal Device into Superior Vena Cava, Open Approach — grouped in MDC 16, the procedure side of this code's crossing.” · check together
- 02HV3DZ — Insertion of Intraluminal Device into Superior Vena Cava, Percutaneous Approach [Same-MDC procedure]: “Insertion of Intraluminal Device into Superior Vena Cava, Percutaneous Approach — grouped in MDC 16, the procedure side of this code's crossing.” · check together
- 02HV42Z — Insertion of Monitoring Device into Superior Vena Cava, Percutaneous Endoscopic Approach [Same-MDC procedure]: “Insertion of Monitoring Device into Superior Vena Cava, Percutaneous Endoscopic Approach — grouped in MDC 16, the procedure side of this code's crossing.” · check together
- 02HV4DZ — Insertion of Intraluminal Device into Superior Vena Cava, Percutaneous Endoscopic Approach [Same-MDC procedure]: “Insertion of Intraluminal Device into Superior Vena Cava, Percutaneous Endoscopic Approach — grouped in MDC 16, the procedure side of this code's crossing.” · check together
- and 1609 more
Index entries
- Eosinophilia (allergic) (idiopathic) (secondary), in disease classified elsewhere[Index term]
Nearest codes (27)
- D72 — Other disorders of white blood cells [Sibling]
- D72.0 — Genetic anomalies of leukocytes [Sibling]
- D72.1 — Eosinophilia [Sibling]
- D72.10 — Eosinophilia, unspecified [Sibling]
- D72.11 — Hypereosinophilic syndrome [HES] [Sibling]
- D72.110 — Idiopathic hypereosinophilic syndrome [IHES] [Sibling]
- D72.111 — Lymphocytic Variant Hypereosinophilic Syndrome [LHES] [Sibling]
- D72.118 — Other hypereosinophilic syndrome [Sibling]
- and 19 more
Change history
- FY2021 — Added to the code set [Change history]
Nearest Codes in This Family
Official ICD-10-CM classifications closest to D72.18 in its code family, with their registry titles.
- D72.110 — Idiopathic hypereosinophilic syndrome [IHES]
- D72.111 — Lymphocytic Variant Hypereosinophilic Syndrome [LHES]
- D72.118 — Other hypereosinophilic syndrome
- D72.119 — Hypereosinophilic syndrome [HES], unspecified
- D72.12 — Drug rash with eosinophilia and systemic symptoms syndrome
- D72.19 — Other eosinophilia
- D72.8 — Other specified disorders of white blood cells
- D72.81 — Decreased white blood cell count
- D72.810 — Lymphocytopenia
- D72.818 — Other decreased white blood cell count