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ICD-10/F32.1

F32.1 ICD-10-CM Code: Major depressive disorder, single episode, moderate

Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.

Inpatient Payment Groups (MS-DRG)

MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v43.0 (FY2026), Appendix B.

A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.

Risk Adjustment (CMS-HCC)

Payment categories this diagnosis maps to under CMS-HCC V28, payment year 2026.

  • HCC 155 — Major Depression, Moderate or Severe, without Psychosis

Other models: CMS-HCC V22 HCC 58 · RxHCC V08 HCC 132

Risk scores depend on the enrollee's full accepted diagnosis set and segment; a category mapping alone does not determine payment.

Official Registry Overview & Definition

Major depressive disorder, single episode, moderate is a billable ICD-10-CM diagnosis code (F32.1).

Official Tabular Instructional Notes

Sequencing, inclusion, and exclusion notes published for F32.1 in the official ICD-10-CM tabular list.

Includes

Conditions the official ICD-10-CM tabular list includes under this code.

  • single episode of agitated depression
  • single episode of depressive reaction
  • single episode of major depression
  • single episode of psychogenic depression
  • single episode of reactive depression
  • single episode of vital depression

Excludes1 — Not Coded Here

Conditions that can never be reported with this code; the two are mutually exclusive.

  • bipolar disorder (F31.-)
  • manic episode (F30.-)
  • recurrent depressive disorder (F33.-)

Excludes2 — Not Included Here

Conditions not covered by this code, but which may be reported alongside it when both are present.

  • adjustment disorder (F43.2)

Nearest Codes in This Family

Official ICD-10-CM classifications closest to F32.1 in its code family, with their registry titles.

  • F32 — Depressive episode
  • F32.0 — Major depressive disorder, single episode, mild
  • F32.2 — Major depressive disorder, single episode, severe without psychotic features
  • F32.3 — Major depressive disorder, single episode, severe with psychotic features
  • F32.4 — Major depressive disorder, single episode, in partial remission
  • F32.5 — Major depressive disorder, single episode, in full remission
  • F32.8 — Other depressive episodes
  • F32.81 — Premenstrual dysphoric disorder
  • F32.89 — Other specified depressive episodes
  • F32.9 — Major depressive disorder, single episode, unspecified

View all codes in the F32 family

Indexed Clinical Terms (2)

Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code.

  • Disorder (of), depressive, major, single episode, moderate
  • Episode, depressive, major, moderate