F32.1 ICD-10-CM Code: Major depressive disorder, single episode, moderate
Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.
Inpatient Payment Groups (MS-DRG)
MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v43.0 (FY2026), Appendix B.
- MS-DRG 885 — PSYCHOSES (MDC 19)
A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.
Risk Adjustment (CMS-HCC)
Payment categories this diagnosis maps to under CMS-HCC V28, payment year 2026.
- HCC 155 — Major Depression, Moderate or Severe, without Psychosis
Other models: CMS-HCC V22 HCC 58 · RxHCC V08 HCC 132
Risk scores depend on the enrollee's full accepted diagnosis set and segment; a category mapping alone does not determine payment.
Official Registry Overview & Definition
Official Tabular Instructional Notes
Sequencing, inclusion, and exclusion notes published for F32.1 in the official ICD-10-CM tabular list.
Includes
Conditions the official ICD-10-CM tabular list includes under this code.
- single episode of agitated depression
- single episode of depressive reaction
- single episode of major depression
- single episode of psychogenic depression
- single episode of reactive depression
- single episode of vital depression
Excludes1 — Not Coded Here
Conditions that can never be reported with this code; the two are mutually exclusive.
- bipolar disorder (F31.-)
- manic episode (F30.-)
- recurrent depressive disorder (F33.-)
Excludes2 — Not Included Here
Conditions not covered by this code, but which may be reported alongside it when both are present.
- adjustment disorder (F43.2)
Nearest Codes in This Family
Official ICD-10-CM classifications closest to F32.1 in its code family, with their registry titles.
- F32 — Depressive episode
- F32.0 — Major depressive disorder, single episode, mild
- F32.2 — Major depressive disorder, single episode, severe without psychotic features
- F32.3 — Major depressive disorder, single episode, severe with psychotic features
- F32.4 — Major depressive disorder, single episode, in partial remission
- F32.5 — Major depressive disorder, single episode, in full remission
- F32.8 — Other depressive episodes
- F32.81 — Premenstrual dysphoric disorder
- F32.89 — Other specified depressive episodes
- F32.9 — Major depressive disorder, single episode, unspecified
Indexed Clinical Terms (2)
Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code.
- Disorder (of), depressive, major, single episode, moderate
- Episode, depressive, major, moderate