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ICD-10/O99.324

O99.324 ICD-10-CM Code: Drug use complicating childbirth

Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.

Inpatient Payment Groups (MS-DRG)

MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v43.0 (FY2026), Appendix B.

  • MS-DRG 998 — PRINCIPAL DIAGNOSIS INVALID AS DISCHARGE DIAGNOSIS (MDC 14)

A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.

Code Set: Valid FY2026 and FY2027. FY2026 took effect October 1, 2025.

Official Registry Overview & Definition

Drug use complicating childbirth is a billable ICD-10-CM diagnosis code (O99.324).

Official Tabular Instructional Notes

Sequencing, inclusion, and exclusion notes published for O99.324 in the official ICD-10-CM tabular list.

Includes

Conditions the official ICD-10-CM tabular list includes under this code.

  • conditions which complicate the pregnant state, are aggravated by the pregnancy or are a main reason for obstetric care

Excludes2 — Not Included Here

Conditions not covered by this code, but which may be reported alongside it when both are present.

  • when the reason for maternal care is that the condition is known or suspected to have affected the fetus (O35-O36)

Use Additional Code

Supplementary codes the tabular list directs you to add.

  • Use additional code(s) from F11-F16 and F18-F19 to identify manifestations of the drug use
  • Use additional code to identify specific condition

Nearest Codes in This Family

Official ICD-10-CM classifications closest to O99.324 in its code family, with their registry titles.

  • O99.32 — Drug use complicating pregnancy, childbirth, and the puerperium
  • O99.320 — Drug use complicating pregnancy, unspecified trimester
  • O99.321 — Drug use complicating pregnancy, first trimester
  • O99.322 — Drug use complicating pregnancy, second trimester
  • O99.323 — Drug use complicating pregnancy, third trimester
  • O99.325 — Drug use complicating the puerperium
  • O99.33 — Tobacco use disorder complicating pregnancy, childbirth, and the puerperium
  • O99.330 — Smoking (tobacco) complicating pregnancy, unspecified trimester
  • O99.331 — Smoking (tobacco) complicating pregnancy, first trimester
  • O99.332 — Smoking (tobacco) complicating pregnancy, second trimester

View all codes in the O99 family

Indexed Clinical Terms (1)

Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code.

  • Delivery (childbirth) (labor), complicated, by, drug use