P27.0 ICD-10-CM Code: Wilson-Mikity syndrome

Coding instructions

Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for P27.0 in the official ICD-10-CM tabular list, quoted as published.

Source: CMS/CDC — ICD-10-CM Tabular ListRelease: FY2026Effective: October 1, 2025

Notes without a marker are published on P27.0 itself; “inherited from” names the category or block whose note applies here.

Coder workflow for P27.0

MedCoder structured workflow — derived from this code’s own official record

Documentation check

The provider’s diagnostic statement

Codes are assigned from the provider’s documented diagnosis, not from clinical criteria, test values or a medication list (Guidelines I.A.19).

Acuity

Acute or chronic as documented; when both are documented and separate codes exist, both are reported with the acute code first (Guidelines I.B.8).

Official instructions as workflow

• Excludes2 — not part of P27.0(1 note)

  Coding workflow: The conditions named in this note are not included in P27.0. When the record documents both, both may be reported; the note is a boundary, not a prohibition.

  See the official tabular notes · Guidelines I.A.12.b

Every row is derived from this code’s own record — its title, tabular notes, 7th-character family and same-category siblings — with fixed MedCoder wording; nothing is inferred about a patient. The official notes and guideline text are in the sections each row links to, and they control.

Indexed Clinical Terms (6)

Official source data — entries quoted as published, in the Index’s own lookup phrasing

Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code. These are alphabetic-index entries shown as the Index writes them — lookup phrasing, not necessarily the wording of a final diagnosis.

• Bubbly lung syndrome
• Dysmaturity, pulmonary (newborn) (Wilson-Mikity)
• Mikity-Wilson disease or syndrome
• Syndrome, bubbly lung
• Syndrome, pulmonary, dysmaturity (Wilson-Mikity)
• Wilson-Mikity syndrome

Don’t confuse P27.0 with…

MedCoder analysis — pairs from this code’s official notes, distinctions written by MedCoder

The codes most likely to be picked instead of P27.0 — named in its own official notes, or sharing its laterality or encounter family — with what separates them and which documentation moves the case. Each links to the full comparison.

• P27.9— Specificity relationship (Review)

  Overlapping diagnoses in the same category.

  Overlapping codes in the same category — the documentation decides which is the more specific fit.

  What moves you there: A record that documents no more than “Unspecified chronic respiratory disease originating in the perinatal period” takes P27.9; specificity in the record moves it back here.

  Full comparison: P27.0 vs P27.9 →

• P22.0— Excludes2 relationship (Informational)

  Distinct conditions — both may be reported.

  A distinct condition — both may be reported when both are documented.

  What moves you there: Documentation of respiratory distress of newborn adds P22.0; it is not part of this code and both may be reported when both are documented.

  Full comparison: P27.0 vs P22.0 →

• P22.9— Excludes2 relationship (Informational)

  Distinct conditions — both may be reported.

  A distinct condition — both may be reported when both are documented.

  What moves you there: Documentation of respiratory distress of newborn adds P22.9; it is not part of this code and both may be reported when both are documented.

  Full comparison: P27.0 vs P22.9 →

Relationships are read from this code's own official notes, its laterality siblings and its encounter family; the wording of each distinction is MedCoder editorial, and the documentation named in each “what moves you there” line is the official note phrase or sibling title itself. Source: CMS ICD-10-CM tabular instructional notes; ICD-10-CM Official Guidelines, Section I.A.12.a.

Verify Before Coding

• MCC as a secondary diagnosis (FY2026). Can raise the stay's MS-DRG severity tier.

From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.

Relationships & Classification

MedCoder structured relationships — computed from published CMS and AHRQ datasets

MS-DRG Grouper Relationships (FY2026)

Potential MS-DRG participation — not a DRG assignment.

FY2026 MS-DRG: MCC — Major Complication or Comorbidity. Reported as a secondary diagnosis, this code raises the stay's MS-DRG severity tier — except when the principal diagnosis is one of 78 clinically related codes on its CMS exclusion list.

Named in the grouper logic of 3 MS-DRGs: DRG 196 (MDC 04), DRG 197 (MDC 04), DRG 198 (MDC 04).

From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.

Clinical classification (AHRQ CCSR):PNL006 — Respiratory perinatal condition (default).

Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.

Related Codes

Same clinical process (MS-DRG)

Acts as MCC — raises the severity of other admissions. CMS groups these diagnoses into one MS-DRG principal-diagnosis exclusion process — a CC/MCC on this list never raises severity when the principal diagnosis is also on it.

P24.9 — Neonatal aspiration, unspecified, P25.0 — Interstitial emphysema originating in the perinatal period, P25.1 — Pneumothorax originating in the perinatal period, P25.2 — Pneumomediastinum originating in the perinatal period, P25.3 — Pneumopericardium originating in the perinatal period, P25.8 — Other conditions related to interstitial emphysema originating in the perinatal period, P26.0 — Tracheobronchial hemorrhage originating in the perinatal period, P26.1 — Massive pulmonary hemorrhage originating in the perinatal period, P26.8 — Other pulmonary hemorrhages originating in the perinatal period, P26.9 — Unspecified pulmonary hemorrhage originating in the perinatal period, P27.1 — Bronchopulmonary dysplasia originating in the perinatal period, P27.8 — Other chronic respiratory diseases originating in the perinatal period, P27.9 — Unspecified chronic respiratory disease originating in the perinatal period, P28.0 — Primary atelectasis of newborn, P28.10 — Unspecified atelectasis of newborn, P28.11 — Resorption atelectasis without respiratory distress syndrome, P28.19 — Other atelectasis of newborn, P28.2 — Cyanotic attacks of newborn, P28.30 — Primary sleep apnea of newborn, unspecified, P28.31 — Primary central sleep apnea of newborn, +57 more

Same CMS-HCC risk category (V28)

CMS maps these diagnoses to the same Hierarchical Condition Category (Cardio-Respiratory Failure and Shock) for risk-adjusted payment.

J96.21 — Acute and chronic respiratory failure with hypoxia, J96.22 — Acute and chronic respiratory failure with hypercapnia, J96.90 — Respiratory failure, unspecified, unspecified whether with hypoxia or hypercapnia, J96.91 — Respiratory failure, unspecified with hypoxia, J96.92 — Respiratory failure, unspecified with hypercapnia, P22.0 — Respiratory distress syndrome of newborn, P26.0 — Tracheobronchial hemorrhage originating in the perinatal period, P26.1 — Massive pulmonary hemorrhage originating in the perinatal period, P26.8 — Other pulmonary hemorrhages originating in the perinatal period, P26.9 — Unspecified pulmonary hemorrhage originating in the perinatal period, P27.1 — Bronchopulmonary dysplasia originating in the perinatal period, P27.8 — Other chronic respiratory diseases originating in the perinatal period, P27.9 — Unspecified chronic respiratory disease originating in the perinatal period, P28.0 — Primary atelectasis of newborn, P28.10 — Unspecified atelectasis of newborn, P28.11 — Resorption atelectasis without respiratory distress syndrome, P28.19 — Other atelectasis of newborn, P28.5 — Respiratory failure of newborn, P29.81 — Cardiac arrest of newborn, R57.0 — Cardiogenic shock, +15 more

Related risk categories

These categories interact through CMS's HCC hierarchy — one can suppress the other's risk-adjustment weight when both are present on a claim.

Respirator Dependence/Tracheostomy Status/Complications, Respiratory Arrest

Same clinical category (CCSR)

AHRQ's Clinical Classifications Software groups these diagnoses under the same clinical category (Respiratory perinatal condition).

P24.9 — Neonatal aspiration, unspecified, P25.0 — Interstitial emphysema originating in the perinatal period, P25.1 — Pneumothorax originating in the perinatal period, P25.2 — Pneumomediastinum originating in the perinatal period, P25.3 — Pneumopericardium originating in the perinatal period, P25.8 — Other conditions related to interstitial emphysema originating in the perinatal period, P26.0 — Tracheobronchial hemorrhage originating in the perinatal period, P26.1 — Massive pulmonary hemorrhage originating in the perinatal period, P26.8 — Other pulmonary hemorrhages originating in the perinatal period, P26.9 — Unspecified pulmonary hemorrhage originating in the perinatal period, P27.1 — Bronchopulmonary dysplasia originating in the perinatal period, P27.8 — Other chronic respiratory diseases originating in the perinatal period, P27.9 — Unspecified chronic respiratory disease originating in the perinatal period, P28.0 — Primary atelectasis of newborn, P28.10 — Unspecified atelectasis of newborn, P28.11 — Resorption atelectasis without respiratory distress syndrome, P28.19 — Other atelectasis of newborn, P28.2 — Cyanotic attacks of newborn, P28.3 — Primary sleep apnea of newborn, P28.30 — Primary sleep apnea of newborn, unspecified, +33 more

Contextual Map

Every relationship of P27.0 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Hierarchy

• P00-P96 — Chapter 16: Certain Conditions Originating in the Perinatal Period (P00-P96) (P00-P96)[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• P19-P29 — Respiratory and cardiovascular disorders specific to the perinatal period[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2026

Clinical classification (CCSR)

• PNL006 — Respiratory perinatal condition[CCSR]— AHRQ CCSR for ICD-10-CM Diagnoses (HCUP)

Risk adjustment (CMS-HCC)

• HCC 213 — Cardio-Respiratory Failure and Shock [CMS-HCC]— CMS-HCC V28 · 2026

MS-DRG Grouper

• MCC — Major Complication or Comorbidity [MS-DRG severity]: “As a secondary diagnosis this code can raise the stay's MS-DRG severity tier (MCC).”— CMS MS-DRG Definitions Manual (Appendix C) · FY2026
• DRG 196 — INTERSTITIAL LUNG DISEASE WITH MCC[MS-DRG]: “INTERSTITIAL LUNG DISEASE WITH MCC (MDC 04)”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026
• DRG 197 — INTERSTITIAL LUNG DISEASE WITH CC[MS-DRG]: “INTERSTITIAL LUNG DISEASE WITH CC (MDC 04)”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026
• DRG 198 — INTERSTITIAL LUNG DISEASE WITHOUT CC/MCC[MS-DRG]: “INTERSTITIAL LUNG DISEASE WITHOUT CC/MCC (MDC 04)”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026

MDC crossing

• MDC 04 — Diseases and Disorders of the Respiratory System[MDC crossing]: “Diseases and Disorders of the Respiratory System — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs. 3,998 same-MDC procedures group here; browse them on the MDC page.”— CMS MS-DRG Definitions Manual · FY2026

Index entries

• Bubbly lung syndrome[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
• Dysmaturity, pulmonary (newborn) (Wilson-Mikity)[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
• Mikity-Wilson disease or syndrome[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
• Syndrome, bubbly lung[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
• Syndrome, pulmonary, dysmaturity (Wilson-Mikity)[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
• Wilson-Mikity syndrome[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026

Nearest codes

• P27 — Chronic respiratory disease originating in the perinatal period[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• P27.1 — Bronchopulmonary dysplasia originating in the perinatal period[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• P27.8 — Other chronic respiratory diseases originating in the perinatal period[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• P27.9 — Unspecified chronic respiratory disease originating in the perinatal period[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026

Change history

• FY2016 — In the code set at ICD-10-CM adoption [Change history]— CMS release files (code change ledger) · icd10cm-fy2016

Sources for this page

Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.

Code, title, tabular notes and index terms Official source data

CMS/CDC ICD-10-CM FY2026 tabular list, index and tables, effective October 1, 2025 Release, file and checksum · Publisher’s page

Claim edits Official source data

CMS Definitions of Medicare Code Edits — v43.1 (April 2026) Release, file and checksum · Publisher’s page

Inpatient payment groups Official source data

CMS MS-DRG Definitions Manual (incl. Appendix B diagnosis index, Appendix C CC/MCC list, Appendix E procedure index) and IPPS Final Rule tables — v43 Release, file and checksum · Publisher’s page

Risk adjustment Official source data

2026 Mid-Year Final ICD-10 Mappings + Model Software (cms.gov/files/zip/2026-midyear-final-icd-10-mappings.zip, 2026-midyear-final-model-software.zip) — CMS-HCC V28, PY2026 mid-year final release Release, file and checksum · Publisher’s page

Change history and date-of-service validity Official source data

CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page

Comparisons, relationships and the contextual map MedCoder structured relationship

Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears

Summary and FAQ answers MedCoder explanation

Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.

Labels on this page: Official source data · MedCoder structured relationship · MedCoder explanation. How to read the labels · All data sources and release dates

Nearest Codes in This Family

Official ICD-10-CM classifications closest to P27.0 in its code family, with their registry titles.

• P27 — Chronic respiratory disease originating in the perinatal period
• P27.1 — Bronchopulmonary dysplasia originating in the perinatal period
• P27.8 — Other chronic respiratory diseases originating in the perinatal period
• P27.9 — Unspecified chronic respiratory disease originating in the perinatal period

View all codes in the P27 family