Q93.88 ICD-10-CM Code: Other microdeletions

Coding instructions

Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for Q93.88 in the official ICD-10-CM tabular list, quoted as published.

Source: CMS/CDC — ICD-10-CM Tabular ListRelease: FY2026Effective: October 1, 2025

Notes without a marker are published on Q93.88 itself; “inherited from” names the category or block whose note applies here.

Coder workflow for Q93.88

MedCoder structured workflow — derived from this code’s own official record

Before you code Q93.88

1. “Other” (NEC) means the condition is specified in the record but no dedicated code captures it. Confirm the documented form is not one a sibling code names before settling on Q93.88; if the record states no specifics at all, the unspecified sibling applies instead. “Other” codes are for documented conditions the classification gives no specific code; “unspecified” codes are for records lacking the detail (Guidelines I.A.9.a, I.A.9.b).

   ReviewQ93.81, Q93.82

   See the relationships section · Guide: Other vs unspecified (NEC vs NOS) →

Documentation check

The provider’s diagnostic statement

Codes are assigned from the provider’s documented diagnosis, not from clinical criteria, test values or a medication list (Guidelines I.A.19).

Any detail beyond this code’s title

What the record states that a more specific sibling code would capture — or its absence, which itself supports the unspecified code.

Official instructions as workflow

• Excludes2 — not part of Q93.88(1 note)

  Coding workflow: The conditions named in this note are not included in Q93.88. When the record documents both, both may be reported; the note is a boundary, not a prohibition.

  CompareE88.4

  See the official tabular notes · Guidelines I.A.12.b

Every row is derived from this code’s own record — its title, tabular notes, 7th-character family and same-category siblings — with fixed MedCoder wording; nothing is inferred about a patient. The official notes and guideline text are in the sections each row links to, and they control.

Indexed Clinical Terms (4)

Official source data — entries quoted as published, in the Index’s own lookup phrasing

Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code. These are alphabetic-index entries shown as the Index writes them — lookup phrasing, not necessarily the wording of a final diagnosis.

• Deletion (s), microdeletions NEC
• Microdeletions NEC
• Syndrome, Miller-Dieker
• Syndrome, Smith-Magenis

Don’t confuse Q93.88 with…

MedCoder analysis — pairs from this code’s official notes, distinctions written by MedCoder

The codes most likely to be picked instead of Q93.88 — named in its own official notes, or sharing its laterality or encounter family — with what separates them and which documentation moves the case. Each links to the full comparison.

• E88.4— Excludes2 relationship (Informational)

  Distinct conditions — both may be reported.

  A distinct condition — both may be reported when both are documented.

  What moves you there: Documentation of mitochondrial metabolic disorders adds E88.4; it is not part of this code and both may be reported when both are documented.

  Full comparison: Q93.88 vs E88.4 →

Relationships are read from this code's own official notes, its laterality siblings and its encounter family; the wording of each distinction is MedCoder editorial, and the documentation named in each “what moves you there” line is the official note phrase or sibling title itself. Source: CMS ICD-10-CM tabular instructional notes; ICD-10-CM Official Guidelines, Section I.A.12.a.

Verify Before Coding

• CC as a secondary diagnosis (FY2026). Can raise the stay's MS-DRG severity tier.

From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.

Relationships & Classification

MedCoder structured relationships — computed from published CMS and AHRQ datasets

Other codes that name Q93.88 or its code family, from the CMS ICD-10-CM tabular instructional notes. Tabular-note edges are stored at the code family level that carries each note.

Referenced by 10 Excludes1 notes across 3 chapters: E25 — Adrenogenital disorders (via Q93.-), Q50 — Congenital malformations of ovaries, fallopian tubes and broad ligaments (via Q93.-), Q50-Q56 — Congenital malformations of genital organs (Q50-Q56) (via Q93.-), Q51 — Congenital malformations of uterus and cervix (via Q93.-), Q52 — Other congenital malformations of female genitalia (via Q93.-), Q53 — Undescended and ectopic testicle (via Q93.-), Q54 — Hypospadias (via Q93.-), Q55 — Other congenital malformations of male genital organs (via Q93.-), Q56 — Indeterminate sex and pseudohermaphroditism (via Q93.-), Z15 — Genetic susceptibility to disease (via Q93.-).

These codes’ tabular lists mark this diagnosis as mutually exclusive — not reported together unless the conditions are documented as unrelated.

Referenced by 1 Code First instruction: D84.81 — Immunodeficiency due to conditions classified elsewhere (via Q93.-).

Each of these codes carries a Code First note naming this condition — when that code is reported, THIS code is sequenced first, ahead of it.

MS-DRG Grouper Relationships (FY2026)

Potential MS-DRG participation — not a DRG assignment.

FY2026 MS-DRG: CC — Complication or Comorbidity. Reported as a secondary diagnosis, this code raises the stay's MS-DRG severity tier — except when the principal diagnosis is one of 68 clinically related codes on its CMS exclusion list.

Named in the grouper logic of 1 MS-DRG: DRG 884 (MDC 19).

From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.

Clinical classification (AHRQ CCSR):MAL009 — Chromosomal abnormalities (default).

Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.

Related Codes

Same clinical process (MS-DRG)

Acts as CC — raises the severity of other admissions. CMS groups these diagnoses into one MS-DRG principal-diagnosis exclusion process — a CC/MCC on this list never raises severity when the principal diagnosis is also on it.

Q93.1 — Whole chromosome monosomy, mosaicism (mitotic nondisjunction), Q93.2 — Chromosome replaced with ring, dicentric or isochromosome, Q93.3 — Deletion of short arm of chromosome 4, Q93.4 — Deletion of short arm of chromosome 5, Q93.51 — Angelman syndrome, Q93.52 — Phelan-McDermid syndrome, Q93.59 — Other deletions of part of a chromosome, Q93.7 — Deletions with other complex rearrangements, Q93.81 — Velo-cardio-facial syndrome, Q93.82 — Williams syndrome, Q93.89 — Other deletions from the autosomes, Q93.9 — Deletion from autosomes, unspecified, Q95.0 — Balanced translocation and insertion in normal individual, Q95.1 — Chromosome inversion in normal individual, Q95.2 — Balanced autosomal rearrangement in abnormal individual, Q95.3 — Balanced sex/autosomal rearrangement in abnormal individual, Q95.5 — Individual with autosomal fragile site, Q95.8 — Other balanced rearrangements and structural markers, Q95.9 — Balanced rearrangement and structural marker, unspecified, Q96.0 — Karyotype 45, X, +47 more

Same clinical category (CCSR)

AHRQ's Clinical Classifications Software groups these diagnoses under the same clinical category (Chromosomal abnormalities).

Q93.2 — Chromosome replaced with ring, dicentric or isochromosome, Q93.3 — Deletion of short arm of chromosome 4, Q93.4 — Deletion of short arm of chromosome 5, Q93.5 — Other deletions of part of a chromosome, Q93.51 — Angelman syndrome, Q93.52 — Phelan-McDermid syndrome, Q93.59 — Other deletions of part of a chromosome, Q93.7 — Deletions with other complex rearrangements, Q93.81 — Velo-cardio-facial syndrome, Q93.82 — Williams syndrome, Q93.89 — Other deletions from the autosomes, Q93.9 — Deletion from autosomes, unspecified, Q95.0 — Balanced translocation and insertion in normal individual, Q95.1 — Chromosome inversion in normal individual, Q95.2 — Balanced autosomal rearrangement in abnormal individual, Q95.3 — Balanced sex/autosomal rearrangement in abnormal individual, Q95.5 — Individual with autosomal fragile site, Q95.8 — Other balanced rearrangements and structural markers, Q95.9 — Balanced rearrangement and structural marker, unspecified, Q96.0 — Karyotype 45, X, +56 more

Contextual Map

Every relationship of Q93.88 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Run Q93.88 with these 9 related codes in Claim Check

Hierarchy

• Q00-QA1 — Chapter 17: Congenital Malformations, Deformations and Chromosomal Abnormalities (Q00-QA1) (Q00-QA1)[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2026

Referenced by Excludes1 notes (10)

• E25 — Adrenogenital disorders[Excludes1](via Q93.-): “chromosomal abnormalities (Q90-Q99)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• Q50 — Congenital malformations of ovaries, fallopian tubes and broad ligaments[Excludes1](via Q93.-): “syndromes associated with anomalies in the number and form of chromosomes (Q90-Q99)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• Q50-Q56 — Congenital malformations of genital organs (Q50-Q56)[Excludes1](via Q93.-): “syndromes associated with anomalies in the number and form of chromosomes (Q90-Q99)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• Q51 — Congenital malformations of uterus and cervix[Excludes1](via Q93.-): “syndromes associated with anomalies in the number and form of chromosomes (Q90-Q99)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• Q52 — Other congenital malformations of female genitalia[Excludes1](via Q93.-): “syndromes associated with anomalies in the number and form of chromosomes (Q90-Q99)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• Q53 — Undescended and ectopic testicle[Excludes1](via Q93.-): “syndromes associated with anomalies in the number and form of chromosomes (Q90-Q99)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• Q54 — Hypospadias[Excludes1](via Q93.-): “syndromes associated with anomalies in the number and form of chromosomes (Q90-Q99)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• Q55 — Other congenital malformations of male genital organs[Excludes1](via Q93.-): “syndromes associated with anomalies in the number and form of chromosomes (Q90-Q99)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• and 2 more

Referenced by Code First instructions

• D84.81 — Immunodeficiency due to conditions classified elsewhere[Code First](via Q93.-): “chromosomal abnormalities (Q90-Q99)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026

Clinical classification (CCSR)

• MAL009 — Chromosomal abnormalities[CCSR]— AHRQ CCSR for ICD-10-CM Diagnoses (HCUP)

MS-DRG Grouper

• CC — Complication or Comorbidity [MS-DRG severity]: “As a secondary diagnosis this code can raise the stay's MS-DRG severity tier (CC).”— CMS MS-DRG Definitions Manual (Appendix C) · FY2026
• DRG 884 — ORGANIC DISTURBANCES AND INTELLECTUAL DISABILITY[MS-DRG]: “ORGANIC DISTURBANCES AND INTELLECTUAL DISABILITY (MDC 19)”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026

MDC crossing

• MDC 19 — Mental Diseases and Disorders[MDC crossing]: “Mental Diseases and Disorders — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs.”— CMS MS-DRG Definitions Manual · FY2026

Index entries

• Deletion (s), microdeletions NEC[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
• Microdeletions NEC[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
• Syndrome, Miller-Dieker[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
• Syndrome, Smith-Magenis[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026

Nearest codes (16)

• Q93 — Monosomies and deletions from the autosomes, not elsewhere classified[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• Q93.0 — Whole chromosome monosomy, nonmosaicism (meiotic nondisjunction)[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• Q93.1 — Whole chromosome monosomy, mosaicism (mitotic nondisjunction)[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• Q93.2 — Chromosome replaced with ring, dicentric or isochromosome[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• Q93.3 — Deletion of short arm of chromosome 4[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• Q93.4 — Deletion of short arm of chromosome 5[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• Q93.5 — Other deletions of part of a chromosome[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• Q93.51 — Angelman syndrome[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• and 8 more

Change history

• FY2016 — In the code set at ICD-10-CM adoption [Change history]— CMS release files (code change ledger) · icd10cm-fy2016

Sources for this page

Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.

Code, title, tabular notes and index terms Official source data

CMS/CDC ICD-10-CM FY2026 tabular list, index and tables, effective October 1, 2025 Release, file and checksum · Publisher’s page

Claim edits Official source data

CMS Definitions of Medicare Code Edits — v43.1 (April 2026) Release, file and checksum · Publisher’s page

Inpatient payment groups Official source data

CMS MS-DRG Definitions Manual (incl. Appendix B diagnosis index, Appendix C CC/MCC list, Appendix E procedure index) and IPPS Final Rule tables — v43 Release, file and checksum · Publisher’s page

Change history and date-of-service validity Official source data

CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page

Comparisons, relationships and the contextual map MedCoder structured relationship

Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears

Summary and FAQ answers MedCoder explanation

Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.

Labels on this page: Official source data · MedCoder structured relationship · MedCoder explanation. How to read the labels · All data sources and release dates

Nearest Codes in This Family

Official ICD-10-CM classifications closest to Q93.88 in its code family, with their registry titles.

• Q93.5 — Other deletions of part of a chromosome
• Q93.51 — Angelman syndrome
• Q93.52 — Phelan-McDermid syndrome
• Q93.59 — Other deletions of part of a chromosome
• Q93.7 — Deletions with other complex rearrangements
• Q93.8 — Other deletions from the autosomes
• Q93.81 — Velo-cardio-facial syndrome
• Q93.82 — Williams syndrome
• Q93.89 — Other deletions from the autosomes
• Q93.9 — Deletion from autosomes, unspecified

View all codes in the Q93 family