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Q97.0 ICD-10-CM Code: Karyotype 47, XXX

Compare with another codeCheck this code on a claim

Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.

Coding at a Glance

Tabular directives
1 Excludes1 · 1 Excludes2

Billable · FY2027A valid, specific ICD-10-CM code, reportable for dates of service in FY2027.

What you need to know

Source: CMS/NCHS Official ICD-10-CM tabular notes, quoted. From the CMS/NCHS tabular list for the release in force. A note the category or block publishes applies to this code too; the Instructions section marks which is which.

Excludes1Never report with this code
  • Turner's syndrome (Q96.-)
Excludes2Not included here; may be reported together
  • mitochondrial metabolic disorders (E88.4-)

Most relevant related codes MedCoder-derived

Read off the official notes above and this code’s own position in the tabular list. Which to report is a documentation question; Compare shows the two side by side.

CompareCheck ClaimView Related Codes

Inpatient Payment Groups (MS-DRG)

Potential MS-DRG participation — not a DRG assignment.

MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v44, Appendix B.

  • MS-DRG 742 — UTERINE AND ADNEXA PROCEDURES FOR NON-MALIGNANCY WITH CC/MCC (MDC 13)
  • MS-DRG 743 — UTERINE AND ADNEXA PROCEDURES FOR NON-MALIGNANCY WITHOUT CC/MCC (MDC 13)
  • MS-DRG 760 — MENSTRUAL AND OTHER FEMALE REPRODUCTIVE SYSTEM DISORDERS WITH CC/MCC (MDC 13)
  • MS-DRG 761 — MENSTRUAL AND OTHER FEMALE REPRODUCTIVE SYSTEM DISORDERS WITHOUT CC/MCC (MDC 13)

A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.

Coding instructions

Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for Q97.0 in the official ICD-10-CM tabular list, quoted as published.

Source: CMS/CDC — ICD-10-CM Tabular ListRelease: FY2027Effective: October 1, 2026

Trace:FY2027 changesChange historyRelease, file and checksum

Notes without a marker are published on Q97.0 itself; “inherited from” names the category or block whose note applies here.

Excludes1 — Not Coded Here

Conditions generally not reported together with this code (Excludes1) -- an error unless the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Source: inherited from Q97

Excludes2 — Not Included Here

Conditions not covered by this code, but which may be reported alongside it when both are present.

Source: inherited from Q90-Q99

Coder workflow for Q97.0

MedCoder structured workflow — derived from this code’s own official record

Before you code Q97.0

  1. Check the Excludes1 note: if the documentation supports a condition named there, do not simply proceed with Q97.0. Excludes1 conditions are not reported together with this code unless the record shows they are unrelated (Guidelines I.A.12.a).

    See the official tabular notes

Choose the right path

  1. Does the documentation support a condition named in Q97.0’s Excludes1 note?
    Yes → Do not simply proceed: review the excluded code. Both are reported only when the record shows the two conditions are unrelated.
    No → Continue.

    ReviewQ96

Consider Q97.0. Then confirm the code is valid for the date of service in the Verify section.

Documentation check

The provider’s diagnostic statement
Codes are assigned from the provider’s documented diagnosis, not from clinical criteria, test values or a medication list (Guidelines I.A.19).
The associated condition or complication
Whether the associated condition the title names is documented; the “with” convention presumes some links, and a provider statement that the conditions are unrelated defeats it (Guidelines I.A.15).

Official instructions as workflow

  • Excludes1 — check before selecting Q97.0(1 note)

    Coding workflow: If the documentation supports a condition named in this note, do not simply proceed with Q97.0: the two are not reported together. The one exception is when the record shows the two conditions are unrelated to each other.

    CompareQ96

    See the official tabular notes · Guidelines I.A.12.a

  • Excludes2 — not part of Q97.0(1 note)

    Coding workflow: The conditions named in this note are not included in Q97.0. When the record documents both, both may be reported; the note is a boundary, not a prohibition.

    CompareE88.4

    See the official tabular notes · Guidelines I.A.12.b

Coding decision scenarios

Pattern scenarios for this code’s structure — decision rules, not clinical cases

Documentation: Both the condition Q97.0 describes and a condition named in its Excludes1 note are documented for the same encounter.

Coding question: Can both codes be reported?

Path: Review the Excludes1 note and the excluded code, and look for a provider statement on whether the two conditions are related.

Reason: Excludes1 means the two are not coded together; the exception is when the record shows the conditions are unrelated to each other (Guidelines I.A.12.a).

ReviewQ96

Every row is derived from this code’s own record — its title, tabular notes, 7th-character family and same-category siblings — with fixed MedCoder wording; nothing is inferred about a patient. The official notes and guideline text are in the sections each row links to, and they control.

Don’t confuse Q97.0 with…

MedCoder analysis — pairs from this code’s official notes, distinctions written by MedCoder

The codes most likely to be picked instead of Q97.0 — named in its own official notes, or sharing its laterality or encounter family — with what separates them and which documentation moves the case. Each links to the full comparison.

  • Q96— Excludes1 conflict (Excludes1 — generally not reported together)

    Not coded here — the tabular list excludes this pair for the same encounter.

    Not reported together with this code, except where the two conditions are documented as unrelated.

    What moves you there: Documentation of Turner's syndrome moves the case to Q96; the two are not reported together unless documented as unrelated.

    Full comparison: Q97.0 vs Q96 →

  • Q97.9— Specificity relationship (Review)

    Overlapping diagnoses in the same category.

    Overlapping codes in the same category — the documentation decides which is the more specific fit.

    What moves you there: A record that documents no more than “Sex chromosome abnormality, female phenotype, unspecified” takes Q97.9; specificity in the record moves it back here.

    Full comparison: Q97.0 vs Q97.9 →

  • E88.4— Excludes2 relationship (Informational)

    Distinct conditions — both may be reported.

    A distinct condition — both may be reported when both are documented.

    What moves you there: Documentation of mitochondrial metabolic disorders adds E88.4; it is not part of this code and both may be reported when both are documented.

    Full comparison: Q97.0 vs E88.4 →

Relationships are read from this code's own official notes, its laterality siblings and its encounter family; the wording of each distinction is MedCoder editorial, and the documentation named in each “what moves you there” line is the official note phrase or sibling title itself. Source: CMS ICD-10-CM tabular instructional notes; ICD-10-CM Official Guidelines, Section I.A.12.a.

Coding context

Guidelines, coding notes, decision aids, relationships (with MS-DRG and CCSR classification), hierarchy, HCC, coverage and the context map: what a coder reaches for after the core. Each section names whether it is official source data, a MedCoder-derived relationship or MedCoder editorial.

Code Overview

Karyotype 47, XXX is a billable ICD-10-CM diagnosis code (Q97.0).

MedCoder summary Summary composed by MedCoder from this code's official ICD-10-CM record. The tabular instructional notes themselves appear verbatim below.

Verify Before Coding

  • No Medicare Code Editor or MS-DRG Definitions Manual restrictions apply to this code.

From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.

Relationships & Classification

MedCoder-derived relationships — computed from published CMS and AHRQ datasets

Other codes that name Q97.0 or its code family, from the CMS ICD-10-CM tabular instructional notes. Tabular-note edges are stored at the code family level that carries each note.

Referenced by 10 Excludes1 notes across 3 chapters: E25 — Adrenogenital disorders (via Q97.-), Q50 — Congenital malformations of ovaries, fallopian tubes and broad ligaments (via Q97.-), Q50-Q56 — Congenital malformations of genital organs (Q50-Q56) (via Q97.-), Q51 — Congenital malformations of uterus and cervix (via Q97.-), Q52 — Other congenital malformations of female genitalia (via Q97.-), Q53 — Undescended and ectopic testicle (via Q97.-), Q54 — Hypospadias (via Q97.-), Q55 — Other congenital malformations of male genital organs (via Q97.-), Q56 — Indeterminate sex and pseudohermaphroditism (via Q97.-), Z15 — Genetic susceptibility to disease (via Q97.-).

These codes’ tabular lists mark this diagnosis as mutually exclusive — not reported together unless the conditions are documented as unrelated.

Referenced by 1 Code First instruction: D84.81 — Immunodeficiency due to conditions classified elsewhere (via Q97.-).

Each of these codes carries a Code First note naming this condition — when that code is reported, THIS code is sequenced first, ahead of it.

MS-DRG Grouper Relationships (FY2027)

Potential MS-DRG participation — not a DRG assignment.

FY2027 MS-DRG: not on the CMS CC/MCC list — as a secondary diagnosis this code does not change MS-DRG severity for that release.

Named in the grouper logic of 4 MS-DRGs: DRG 742 (MDC 13), DRG 743 (MDC 13), DRG 760 (MDC 13), DRG 761 (MDC 13).

From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.

Clinical classification (AHRQ CCSR):MAL009 — Chromosomal abnormalities (default).

Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.

Related Codes

Same clinical category (CCSR)

AHRQ's Clinical Classifications Software groups these diagnoses under the same clinical category (Chromosomal abnormalities).

Q95.5 — Individual with autosomal fragile site, Q95.8 — Other balanced rearrangements and structural markers, Q95.9 — Balanced rearrangement and structural marker, unspecified, Q96.0 — Karyotype 45, X, Q96.1 — Karyotype 46, X iso (Xq), Q96.2 — Karyotype 46, X with abnormal sex chromosome, except iso (Xq), Q96.3 — Mosaicism, 45, X/46, XX or XY, Q96.4 — Mosaicism, 45, X/other cell line(s) with abnormal sex chromosome, Q96.8 — Other variants of Turner's syndrome, Q96.9 — Turner's syndrome, unspecified, Q97.1 — Female with more than three X chromosomes, Q97.2 — Mosaicism, lines with various numbers of X chromosomes, Q97.3 — Female with 46, XY karyotype, Q97.8 — Other specified sex chromosome abnormalities, female phenotype, Q97.9 — Sex chromosome abnormality, female phenotype, unspecified, Q98.0 — Klinefelter syndrome karyotype 47, XXY, Q98.1 — Klinefelter syndrome, male with more than two X chromosomes, Q98.3 — Other male with 46, XX karyotype, Q98.4 — Klinefelter syndrome, unspecified, Q98.5 — Karyotype 47, XYY, +56 more

Same Index main term, other category

The ICD-10-CM Index to Diseases and Injuries files this code under the main terms “Karyotype”, “Triple”; these codes share that main term but sit in a different category of the Tabular List.

Q50.32 — Ovarian streak (46,XX, with streak gonads), Q51.818 — Other congenital malformations of uterus (uteri), Q56.1 — Male pseudohermaphroditism, not elsewhere classified (46,XY, with streak gonads), Q63.0 — Accessory kidney (kidneys), Q96.0 — Karyotype 45, X (45,X), Q96.1 — Karyotype 46, X iso (Xq) (46,X, iso), Q96.2 — Karyotype 46, X with abnormal sex chromosome, except iso (Xq) (with abnormality except iso), Q98.0 — Klinefelter syndrome karyotype 47, XXY (47,XXY), Q98.3 — Other male with 46, XX karyotype (46,XX), Q98.5 — Karyotype 47, XYY (47,XYY), Q99.1 — 46, XX true hermaphrodite (46,XX, hermaphrodite), Z17.421 — Hormone receptor negative with human epidermal growth factor receptor 2 negative status (negative breast cancer)

Contextual Map

Every relationship of Q97.0 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Run Q97.0 with these 9 related codes in Claim Check

Hierarchy

Referenced by Excludes1 notes (10)

Referenced by Code First instructions

Clinical classification (CCSR)

MS-DRG Grouper

MDC crossing

  • MDC 13 — Diseases and Disorders of the Female Reproductive System[MDC crossing]: “Diseases and Disorders of the Female Reproductive System — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs. 2,238 same-MDC procedures group here; browse them on the MDC page.”— CMS MS-DRG Definitions Manual · FY2027

Index entries

  • Karyotype, 47,XXX[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2027
  • Syndrome, triple X, female[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2027
  • Triple, X, female[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2027

Nearest codes

Change history

  • FY2016 — In the code set at ICD-10-CM adoption [Change history]— CMS release files (code change ledger) · icd10cm-fy2016

Reference

Index terms and tables, published questions and FAQ, every source behind this page with its release and checksum, the date-of-service check and the complete change history.

Indexed Clinical Terms (3)

Official source data — entries quoted as published, in the Index’s own lookup phrasing

Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code. These are alphabetic-index entries shown as the Index writes them — lookup phrasing, not necessarily the wording of a final diagnosis.

Sources for this page

Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.

Code, title, tabular notes and index terms Official source data
CMS/CDC ICD-10-CM FY2027 tabular list, index and tables, effective October 1, 2026 Release, file and checksum · Publisher’s page
Claim edits Official source data
CMS Definitions of Medicare Code Edits — v44.0 (October 2026) Release, file and checksum · Publisher’s page
Inpatient payment groups Official source data
CMS MS-DRG Definitions Manual (incl. Appendix B diagnosis index, Appendix C CC/MCC list, Appendix E procedure index) and IPPS Final Rule tables — v44 Release, file and checksum · Publisher’s page
Change history and date-of-service validity Official source data
CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page
Comparisons, relationships and the contextual map MedCoder-derived relationship
Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears
Summary and FAQ answers MedCoder editorial explanation
Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.

Current data releases:ICD-10-CM FY2027 · ICD-10-PCS FY2027 · HCPCS October 2026 · MS-DRG v44 · Medicare Code Editor v44.0 · NCCI PTP Q4 2026 · MUE Q4 2026 · NCD code lists 2026-01 · LCD export September 20, 2026 · All releases and sources

Labels on this page: Official source data · MedCoder-derived relationship · MedCoder editorial explanation. How to read the labels · All data sources and release dates · CMS coding rules

Cite this page

Reference this page in a research guide, syllabus or article. The release is included because code content changes each year.

MedCoder.ai. "Q97.0 — Karyotype 47, XXX." ICD-10-CM FY2027. https://medcoder.ai/icd10/code/q97.0-karyotype-47-xxx

Change history

  • FY2016 — October 1, 2015
    In the code set at ICD-10-CM adoption
    Karyotype 47, XXX

No changes since FY2016 — additions, deletions, description changes and billable-status changes are tracked through FY2027, and none are recorded for this code. Note changes are tracked from FY2027 only.

Nearest Codes in This Family

Official ICD-10-CM classifications closest to Q97.0 in its code family, with their registry titles.

View all codes in the Q97 family