T40.69 ICD-10-CM Code: Poisoning by, adverse effect of and underdosing of other narcotics
Billing Status: NO. This is a clinician non-billable / parent hierarchy grouping in the ICD-10-CM system.
Coding at a Glance
- 7th character
- Required — see the character table on this page
Coding instructions
Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for T40.69 in the official ICD-10-CM tabular list, quoted as published.
Notes without a marker are published on T40.69 itself; “inherited from” names the category or block whose note applies here.
Includes
Conditions the official ICD-10-CM tabular list includes under this code.
- adverse effect of correct substance properly administered
- poisoning by overdose of substance
- poisoning by wrong substance given or taken in error
- underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed
Source: inherited from T36-T50
Excludes1 — Not Coded Here
Conditions generally not reported together with this code (Excludes1) -- an error unless the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
- toxic reaction to local anesthesia in pregnancy (O29.3-) Compare T40.69 vs O29.3 →
Source: inherited from T36-T50
Excludes2 — Not Included Here
Conditions not covered by this code, but which may be reported alongside it when both are present.
- drug dependence and related mental and behavioral disorders due to psychoactive substance use (F10.-F19.-) inherited from T40Compare T40.69 vs F10 →
- abuse and dependence of psychoactive substances (F10-F19) inherited from T36-T50Compare T40.69 vs F10 →
- abuse of non-dependence-producing substances (F55.-) inherited from T36-T50Compare T40.69 vs F55 →
- immunodeficiency due to drugs (D84.821) inherited from T36-T50Compare T40.69 vs D84.821 →
- drug reaction and poisoning affecting newborn (P00-P96) inherited from T36-T50Compare T40.69 vs P00 →
- pathological drug intoxication (inebriation) (F10-F19) inherited from T36-T50Compare T40.69 vs F10 →
Code First
Underlying conditions that must be sequenced before this code.
- Code first, for adverse effects, the nature of the adverse effect, such as:
- adverse effect NOS (T88.7)
- aspirin gastritis (K29.-)
- blood disorders (D56-D76)
- contact dermatitis (L23-L25)
- dermatitis due to substances taken internally (L27.-)
- nephropathy (N14.0-N14.2)
Source: inherited from T36-T50
Use Additional Code
Supplementary codes the tabular list directs you to add.
- Use additional code(s) to specify:
- manifestations of poisoning
- underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
- underdosing of medication regimen (Z91.12-, Z91.13-)
Source: inherited from T36-T50
7th Character Guide
"The appropriate 7th character is to be added to each code from category T40"
- A — initial encounter
- D — subsequent encounter
- S — sequela
How the encounter character is assigned. “Initial encounter” means the patient is receiving active treatment for the condition — it is not limited to the first visit, and a different or new provider giving active treatment still assigns it. “Subsequent encounter” covers care during the healing or recovery phase after active treatment. “Sequela” is for complications or conditions that arise as a direct result of the original condition.
ICD-10-CM Official Guidelines for Coding and Reporting, Section I.C.19.a (paraphrased by MedCoder).
Variant codes in this family
T40.691A, T40.691D, T40.691S, T40.692A, T40.692D, T40.692S, T40.693A, T40.693D
Character meanings are CMS's official 7th-character extensions for this family, as carried in each variant code's official description; variant codes are registry rows. The explanation of how the encounter character is assigned is MedCoder editorial, distinct from the official content above it.
Code Overview
MedCoder summary Summary composed by MedCoder from this code's official ICD-10-CM record. The tabular instructional notes themselves appear verbatim below.
Decision Points
The directives on this code's own record, as a pre-claim checklist.
- A 7th character applies in this family. Confirm the documented encounter matches the character assigned. See the official 7th-character definitions and this code’s variants
- Sequencing: 7 Code First instructions — the underlying condition is sequenced before this code when present. See the Code First notes
- 4 Use Additional Code instructions — report the named additional code(s) when the documentation supports them. See the Use Additional Code notes
- 1 Excludes1 entry — codes named there are generally not reported together with this code (Guidelines I.A.12.a). See the Excludes1 notes
- 6 Excludes2 entries — those conditions are not part of this code and may be reported additionally when documented. See the Excludes2 notes
Checklist rows are derived from this code's own official directives; the wording of each check is MedCoder editorial. The official notes themselves are in the sections each row links to.
Verify Before Coding
- Not billable as written — a more specific code is required: T40.691A, T40.691D, T40.691S, T40.692A, T40.692D.
- Requires a 7th character. "The appropriate 7th character is to be added to each code from category T40" Options: T40.691A, T40.691D, T40.691S, T40.692A, T40.692D, T40.692S
From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.
Relationships & Classification
Other codes that name T40.69 or its code family, from the CMS ICD-10-CM tabular instructional notes. Tabular-note edges are stored at the code family level that carries each note.
Referenced by 1 Excludes1 note: T41 — Poisoning by, adverse effect of and underdosing of anesthetics and therapeutic gases (via T40.-).
These codes’ tabular lists mark this diagnosis as mutually exclusive — not reported together unless the conditions are documented as unrelated.
Referenced by 14 Excludes2 notes across 3 chapters: F11.2 — Opioid dependence (via T40.-), T41.3 — Poisoning by, adverse effect of and underdosing of local anesthetics (via T40.-), T43 — Poisoning by, adverse effect of and underdosing of psychotropic drugs, not elsewhere classified (via T40.-), T80 — Complications following infusion, transfusion and therapeutic injection (via T40.-), T80-T88 — Complications of surgical and medical care, not elsewhere classified (T80-T88) (via T40.-), T81 — Complications of procedures, not elsewhere classified (via T40.-), T82 — Complications of cardiac and vascular prosthetic devices, implants and grafts (via T40.-), T83 — Complications of genitourinary prosthetic devices, implants and grafts (via T40.-), T84 — Complications of internal orthopedic prosthetic devices, implants and grafts (via T40.-), T85 — Complications of other internal prosthetic devices, implants and grafts (via T40.-), T86 — Complications of transplanted organs and tissue (via T40.-), T87 — Complications peculiar to reattachment and amputation (via T40.-), T88 — Other complications of surgical and medical care, not elsewhere classified (via T40.-), Y63 — Failure in dosage during surgical and medical care (via T40.-).
These codes’ tabular lists name this diagnosis as distinct — both may be reported when both are documented.
Referenced by 20 Code First instructions across 13 chapters: D64.2 — Secondary sideroblastic anemia due to drugs and toxins (via T40.-), E03.2 — Hypothyroidism due to medicaments and other exogenous substances (via T40.-), E09 — Drug or chemical induced diabetes mellitus (via T40.-), F02 — Dementia in other diseases classified elsewhere (via T40.-), G92.8 — Other toxic encephalopathy (via T40.-), G92.9 — Unspecified toxic encephalopathy (via T40.-), H35.38 — Toxic maculopathy (via T40.-), H91.0 — Ototoxic hearing loss (via T40.-), I42.7 — Cardiomyopathy due to drug and external agent (via T40.-), K22.1 — Ulcer of esophagus (via T40.-), K71 — Toxic liver disease (via T40.-), L53.0 — Toxic erythema (via T40.-), M34.2 — Systemic sclerosis induced by drug and chemical (via T40.-), N14 — Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions (via T40.-), P58.4 — Neonatal jaundice due to drugs or toxins transmitted from mother or given to newborn (via T40.-), Z91.12 — Patient's intentional underdosing of medication regimen (via T40.-), Z91.13 — Patient's unintentional underdosing of medication regimen (via T40.-), Z91.14 — Patient's other noncompliance with medication regimen (via T40.-), Z91.A2 — Caregiver's intentional underdosing of patient's medication regimen (via T40.-), Z91.A3 — Caregiver's unintentional underdosing of patient's medication regimen (via T40.-).
Each of these codes carries a Code First note naming this condition — when that code is reported, THIS code is sequenced first, ahead of it.
Referenced by 99 Use Additional Code instructions across 15 chapters: D46 — Myelodysplastic syndromes (via T40.-), D52.1 — Drug-induced folate deficiency anemia (via T40.-), D59.0 — Drug-induced autoimmune hemolytic anemia (via T40.-), D59.2 — Drug-induced nonautoimmune hemolytic anemia (via T40.-), D59.39 — Other hemolytic-uremic syndrome (via T40.-), D61.1 — Drug-induced aplastic anemia (via T40.-), D64.2 — Secondary sideroblastic anemia due to drugs and toxins (via T40.-), D70.2 — Other drug-induced agranulocytosis (via T40.-), D72.12 — Drug rash with eosinophilia and systemic symptoms syndrome (via T40.-), D84.821 — Immunodeficiency due to drugs (via T40.-), D89.3 — Immune reconstitution syndrome (via T40.-), E03.2 — Hypothyroidism due to medicaments and other exogenous substances (via T40.-), E06.4 — Drug-induced thyroiditis (via T40.-), E09 — Drug or chemical induced diabetes mellitus (via T40.-), E16.0 — Drug-induced hypoglycemia without coma (via T40.-), E22.1 — Hyperprolactinemia (via T40.-), E23.1 — Drug-induced hypopituitarism (via T40.-), E24.2 — Drug-induced Cushing's syndrome (via T40.-), E25.8 — Other adrenogenital disorders (via T40.-), E27.3 — Drug-induced adrenocortical insufficiency (via T40.-), +79 more.
These codes instruct coders to additionally report this code when it applies.
Referenced by 1 Code Also instruction: Z91.1 — Patient's noncompliance with medical treatment and regimen (via T40.-).
These codes suggest coding this condition alongside when both are present.
Contextual Map
Every relationship of T40.69 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.
Run T40.69 with these 24 related codes in Claim Check
Hierarchy
- S00-T88 — Chapter 19: Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88) (S00-T88)[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
Referenced by Excludes1 notes
- T41 — Poisoning by, adverse effect of and underdosing of anesthetics and therapeutic gases[Excludes1](via T40.-): “opioids (T40.0-T40.2-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
Referenced by Excludes2 notes (14)
- F11.2 — Opioid dependence[Excludes2](via T40.-): “opioid poisoning (T40.0-T40.2-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- T41.3 — Poisoning by, adverse effect of and underdosing of local anesthetics[Excludes2](via T40.-): “poisoning by cocaine used as a central nervous system stimulant (T40.5X1-T40.5X4)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- T43 — Poisoning by, adverse effect of and underdosing of psychotropic drugs, not elsewhere classified[Excludes2](via T40.-): “psychodysleptics [hallucinogens] (T40.7-T40.9-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- T80 — Complications following infusion, transfusion and therapeutic injection[Excludes2](via T40.-): “poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4 or 6)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- T80-T88 — Complications of surgical and medical care, not elsewhere classified (T80-T88)[Excludes2](via T40.-): “poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4 or 6)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- T81 — Complications of procedures, not elsewhere classified[Excludes2](via T40.-): “poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- T82 — Complications of cardiac and vascular prosthetic devices, implants and grafts[Excludes2](via T40.-): “poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4 or 6)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- T83 — Complications of genitourinary prosthetic devices, implants and grafts[Excludes2](via T40.-): “poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4 or 6)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- and 6 more
Referenced by Code First instructions (20)
- D64.2 — Secondary sideroblastic anemia due to drugs and toxins[Code First](via T40.-): “poisoning due to drug or toxin, if applicable (T36-T65 with fifth or sixth character 1-4)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- E03.2 — Hypothyroidism due to medicaments and other exogenous substances[Code First](via T40.-): “poisoning due to drug or toxin, if applicable (T36-T65 with fifth or sixth character 1-4)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- E09 — Drug or chemical induced diabetes mellitus[Code First](via T40.-): “poisoning due to drug or toxin, if applicable (T36-T65 with fifth or sixth character 1-4)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- F02 — Dementia in other diseases classified elsewhere[Code First](via T40.-): “intoxications (T36-T65)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- G92.8 — Other toxic encephalopathy[Code First](via T40.-): “poisoning due to drug or toxin, if applicable, (T36-T65 with fifth or sixth character 1-4)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- G92.9 — Unspecified toxic encephalopathy[Code First](via T40.-): “poisoning due to drug or toxin, if applicable, (T36-T65 with fifth or sixth character 1-4)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- H35.38 — Toxic maculopathy[Code First](via T40.-): “poisoning due to drug or toxin, if applicable (T36-T65 with fifth or sixth character 1-4)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- H91.0 — Ototoxic hearing loss[Code First](via T40.-): “poisoning due to drug or toxin, if applicable (T36-T65 with fifth or sixth character 1-4)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- and 12 more
Referenced by Use Additional Code instructions (99)
- D46 — Myelodysplastic syndromes[Use Additional Code](via T40.-): “code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- D52.1 — Drug-induced folate deficiency anemia[Use Additional Code](via T40.-): “code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- D59.0 — Drug-induced autoimmune hemolytic anemia[Use Additional Code](via T40.-): “code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- D59.2 — Drug-induced nonautoimmune hemolytic anemia[Use Additional Code](via T40.-): “code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- D59.39 — Other hemolytic-uremic syndrome[Use Additional Code](via T40.-): “code, if applicable, for adverse effect to identify drug (T36-T50 with fifth or sixth character 5)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- D61.1 — Drug-induced aplastic anemia[Use Additional Code](via T40.-): “code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- D64.2 — Secondary sideroblastic anemia due to drugs and toxins[Use Additional Code](via T40.-): “code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- D70.2 — Other drug-induced agranulocytosis[Use Additional Code](via T40.-): “code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- and 91 more
Referenced by Code Also instructions
- Z91.1 — Patient's noncompliance with medical treatment and regimen[Code Also](via T40.-): “, if applicable, to identify underdosing of specific drug (T36-T50 with final character 6)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
Nearest codes (40)
- T40 — Poisoning by, adverse effect of and underdosing of narcotics and psychodysleptics [hallucinogens][Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- T40.602 — Poisoning by unspecified narcotics, intentional self-harm[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- T40.602A — Poisoning by unspecified narcotics, intentional self-harm, initial encounter[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- T40.602D — Poisoning by unspecified narcotics, intentional self-harm, subsequent encounter[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- T40.602S — Poisoning by unspecified narcotics, intentional self-harm, sequela[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- T40.603 — Poisoning by unspecified narcotics, assault[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- T40.603A — Poisoning by unspecified narcotics, assault, initial encounter[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- T40.603D — Poisoning by unspecified narcotics, assault, subsequent encounter[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- and 32 more
Change history
- FY2016 — In the code set at ICD-10-CM adoption [Change history]— CMS release files (code change ledger) · icd10cm-fy2016
Common coding questions
Can T40.69 be billed directly?
No. T40.69 (Poisoning by, adverse effect of and underdosing of other narcotics) is a non-billable ICD-10-CM category code. A more specific billable subcode must be selected based on clinical documentation.
Does T40.69 require a 7th character?
Yes. The appropriate 7th character is to be added to each code from category T40.
Sources for this page
Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.
- Code, title, tabular notes and index terms Official source data
- CMS/CDC ICD-10-CM FY2026 tabular list, index and tables, effective October 1, 2025 Release, file and checksum · Publisher’s page
- Claim edits Official source data
- CMS Definitions of Medicare Code Edits — v43.1 (April 2026) Release, file and checksum · Publisher’s page
- Change history and date-of-service validity Official source data
- CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page
- Comparisons, relationships and the contextual map MedCoder structured relationship
- Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears
- Summary and FAQ answers MedCoder explanation
- Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.
Labels on this page: Official source data · MedCoder structured relationship · MedCoder explanation. How to read the labels · All data sources and release dates
Change history
- FY2016 — October 1, 2015In the code set at ICD-10-CM adoptionPoisoning by, adverse effect of and underdosing of other narcotics
No changes since FY2016 — additions, deletions, description changes and billable-status changes are tracked through FY2027 (effective October 1, 2026), and none are recorded for this code. Note changes are tracked from FY2027 only.
Nearest Codes in This Family
Official ICD-10-CM classifications closest to T40.69 in its code family, with their registry titles.
- T40.605S — Adverse effect of unspecified narcotics, sequela
- T40.606 — Underdosing of unspecified narcotics
- T40.606A — Underdosing of unspecified narcotics, initial encounter
- T40.606D — Underdosing of unspecified narcotics, subsequent encounter
- T40.606S — Underdosing of unspecified narcotics, sequela
- T40.691 — Poisoning by other narcotics, accidental (unintentional)
- T40.691A — Poisoning by other narcotics, accidental (unintentional), initial encounter
- T40.691D — Poisoning by other narcotics, accidental (unintentional), subsequent encounter
- T40.691S — Poisoning by other narcotics, accidental (unintentional), sequela
- T40.692 — Poisoning by other narcotics, intentional self-harm