T86.8402 ICD-10-CM Code: Corneal transplant rejection, left eye

Coding instructions

Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for T86.8402 in the official ICD-10-CM tabular list, quoted as published.

Source: CMS/CDC — ICD-10-CM Tabular ListRelease: FY2026Effective: October 1, 2025

Notes without a marker are published on T86.8402 itself; “inherited from” names the category or block whose note applies here.

7th Character Guide

• 1 — right eye
• 2 — left eye (this page’s code)
• 3 — bilateral
• 9 — unspecified eye

Variant codes in this family

T86.8401, T86.8402, T86.8403, T86.8409

Character meanings are CMS's official 7th-character extensions for this family, as carried in each variant code's official description; variant codes are registry rows. The explanation of how the encounter character is assigned is MedCoder editorial, distinct from the official content above it.

Coder workflow for T86.8402

MedCoder structured workflow — derived from this code’s own official record

Before you code T86.8402

1. A 7th character is required in this family. Confirm the documentation supports the character assigned — its meaning in this family is defined in the official instruction. This page’s code carries “2”. The official 7th-character definitions for this family are quoted in the guide.

   See the 7th Character Guide

2. Laterality is coded in this family. Confirm the side documented — right, left, or bilateral — and select the matching code (this page’s code: left). The unspecified-side code applies only when the record states no side. Laterality is assigned from the documented side; where a bilateral code exists and both sides are documented, it is used instead of two unilateral codes (Guidelines I.B.13).

   See the relationships section · Guide: Laterality coding →

Choose the right path

1. Is the side documented?
   Yes → Select the code for the documented side (or the bilateral code when both sides are documented and one exists).
   No → Use the unspecified-side code only when the record states no side; a query is the alternative.
2. Does the documentation support one of this family’s 7th-character values?
   Yes → Assign the matching 7th character; the variant codes are in the 7th Character Guide.
   No → The code is invalid without its 7th character — query for the missing element.

Consider T86.8402. Then work the Use Additional Code note, and confirm the code is valid for the date of service in the Verify section.

Documentation check

The provider’s diagnostic statement

Codes are assigned from the provider’s documented diagnosis, not from clinical criteria, test values or a medication list (Guidelines I.A.19).

Laterality

Right, left or bilateral as documented; unspecified only when the record states no side (Guidelines I.B.13).

7th-character basis

The documented element this family’s 7th character records (see the official definitions in the 7th Character Guide).

The conditions the Use Additional Code note names

Reported with this code when documented; a conditional instruction (“if applicable”, “if known”) applies only when the record supports it.

Official instructions as workflow

• Excludes2 — not part of T86.8402(22 notes)

  Coding workflow: The conditions named in this note are not included in T86.8402. When the record documents both, both may be reported; the note is a boundary, not a prohibition.

  CompareT85.3, Z93, Z43, Z44, R50.82, G97.0

  See the official tabular notes · Guidelines I.A.12.b

• Use Additional Code — after identifying T86.8402(7 notes)

  Coding workflow: Check whether the documentation supports the additional code(s) the note names, and report them with T86.8402 when it does. Where the instruction is conditional (“if applicable”, “if known”), it applies only when the record documents the condition.

  ReviewD89.81, C80.2, D47.Z1

  See the official tabular notes · Guidelines I.A.13

Coding decision scenarios

Pattern scenarios for this code’s structure — decision rules, not clinical cases

Every row is derived from this code’s own record — its title, tabular notes, 7th-character family and same-category siblings — with fixed MedCoder wording; nothing is inferred about a patient. The official notes and guideline text are in the sections each row links to, and they control.

Official Coding Guidelines

Official source data — quoted verbatim from the CMS/NCHS Official Guidelines

Official source data — quoted verbatim from the CMS/NCHS Official Guidelines

Verbatim excerpts from the ICD-10-CM Official Guidelines for Coding and Reporting (CMS/NCHS) that govern this code.

Don’t confuse T86.8402 with…

MedCoder analysis — pairs from this code’s official notes, distinctions written by MedCoder

The codes most likely to be picked instead of T86.8402 — named in its own official notes, or sharing its laterality or encounter family — with what separates them and which documentation moves the case. Each links to the full comparison.

• T86.8409— Specificity relationship (Review)

  Overlapping diagnoses in the same category.

  Overlapping codes in the same category — the documentation decides which is the more specific fit.

  What moves you there: A record that documents no more than “Corneal transplant rejection, unspecified eye” takes T86.8409; specificity in the record moves it back here.

  Full comparison: T86.8402 vs T86.8409 →

• T86.8401— Laterality relationship (Review)

  Same condition; these differ only in which side is documented.

  The same condition on the other side; the documented side decides, and a bilateral code, where one exists, replaces the pair when both sides are documented.

  What moves you there: A documented right side moves the case to T86.8401.

  Full comparison: T86.8402 vs T86.8401 →

• T86.8403— Laterality relationship (Review)

  Same condition; these differ only in which side is documented.

  The same condition on the other side; the documented side decides, and a bilateral code, where one exists, replaces the pair when both sides are documented.

  What moves you there: Documentation of both sides moves the case to T86.8403.

  Full comparison: T86.8402 vs T86.8403 →

• T85.3— Excludes2 relationship (Informational)

  Distinct conditions — both may be reported.

  A distinct condition — both may be reported when both are documented.

  What moves you there: Documentation of mechanical complications of corneal graft adds T85.3; it is not part of this code and both may be reported when both are documented.

  Full comparison: T86.8402 vs T85.3 →

• Z93— Excludes2 relationship (Informational)

  Distinct conditions — both may be reported.

  A distinct condition — both may be reported when both are documented.

  What moves you there: Documentation of artificial opening status adds Z93; it is not part of this code and both may be reported when both are documented.

  Full comparison: T86.8402 vs Z93 →

• Z43— Excludes2 relationship (Informational)

  Distinct conditions — both may be reported.

  A distinct condition — both may be reported when both are documented.

  What moves you there: Documentation of closure of external stoma adds Z43; it is not part of this code and both may be reported when both are documented.

  Full comparison: T86.8402 vs Z43 →

Relationships are read from this code's own official notes, its laterality siblings and its encounter family; the wording of each distinction is MedCoder editorial, and the documentation named in each “what moves you there” line is the official note phrase or sibling title itself. Source: CMS ICD-10-CM tabular instructional notes; ICD-10-CM Official Guidelines, Section I.A.12.a.

Decision Points

The directives on this code's own record, as a pre-claim checklist.

1. A 7th character applies in this family. Confirm the documented encounter matches the character assigned. See the official 7th-character definitions and this code’s variants
2. Laterality is coded in this family. Confirm the documented side matches the code — the opposite-side siblings are in the relationships section. See the opposite-side sibling codes
3. 7 Use Additional Code instructions — report the named additional code(s) when the documentation supports them. See the Use Additional Code notes
4. 22 Excludes2 entries — those conditions are not part of this code and may be reported additionally when documented. See the Excludes2 notes

Checklist rows are derived from this code's own official directives; the wording of each check is MedCoder editorial. The official notes themselves are in the sections each row links to.

Verify Before Coding

• CC as a secondary diagnosis (FY2026). Can raise the stay's MS-DRG severity tier.

From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.

Relationships & Classification

MedCoder structured relationships — computed from published CMS and AHRQ datasets

Other codes that name T86.8402 or its code family, from the CMS ICD-10-CM tabular instructional notes. Tabular-note edges are stored at the code family level that carries each note.

Referenced by 2 Excludes1 notes across 2 chapters: T88.7 — Unspecified adverse effect of drug or medicament (via T86.-), Z98.85 — Transplanted organ removal status (via T86.-).

These codes’ tabular lists mark this diagnosis as mutually exclusive — not reported together unless the conditions are documented as unrelated.

Referenced by 9 Excludes2 notes across 2 chapters: D89 — Other disorders involving the immune mechanism, not elsewhere classified (via T86.-), T78 — Adverse effects, not elsewhere classified (via T86.-), T79 — Certain early complications of trauma, not elsewhere classified (via T86.-), T81 — Complications of procedures, not elsewhere classified (via T86.-), T82 — Complications of cardiac and vascular prosthetic devices, implants and grafts (via T86.-), T83 — Complications of genitourinary prosthetic devices, implants and grafts (via T86.-), T84 — Complications of internal orthopedic prosthetic devices, implants and grafts (via T86.-), T85 — Complications of other internal prosthetic devices, implants and grafts (via T86.-), T85.3 — Mechanical complication of other ocular prosthetic devices, implants and grafts (via T86.84.-).

These codes’ tabular lists name this diagnosis as distinct — both may be reported when both are documented.

Referenced by 4 Code First instructions across 2 chapters: C80.2 — Malignant neoplasm associated with transplanted organ (via T86.-), D47.Z1 — Post-transplant lymphoproliferative disorder (PTLD) (via T86.-), D89.81 — Graft-versus-host disease (via T86.-), D89.83 — Cytokine release syndrome (via T86.-).

Each of these codes carries a Code First note naming this condition — when that code is reported, THIS code is sequenced first, ahead of it.

MS-DRG Grouper Relationships (FY2026)

Potential MS-DRG participation — not a DRG assignment.

FY2026 MS-DRG: CC — Complication or Comorbidity. Reported as a secondary diagnosis, this code raises the stay's MS-DRG severity tier — except when the principal diagnosis is one of 8 clinically related codes on its CMS exclusion list.

Named in the grouper logic of 2 MS-DRGs: DRG 124 (MDC 02), DRG 125 (MDC 02).

From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.

Clinical classification (AHRQ CCSR):INJ036 — Complication of transplanted organs or tissue, initial encounter (default).

Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.

Related Codes

Same clinical process (MS-DRG)

Acts as CC — raises the severity of other admissions. CMS groups these diagnoses into one MS-DRG principal-diagnosis exclusion process — a CC/MCC on this list never raises severity when the principal diagnosis is also on it.

T86.8401 — Corneal transplant rejection, right eye, T86.8403 — Corneal transplant rejection, bilateral, T86.8409 — Corneal transplant rejection, unspecified eye, T86.8411 — Corneal transplant failure, right eye, T86.8412 — Corneal transplant failure, left eye, T86.8413 — Corneal transplant failure, bilateral, T86.8419 — Corneal transplant failure, unspecified eye

Same condition, opposite side

Same category and title, differing only in which side of the body is affected.

T86.8401 — Corneal transplant rejection, right eye (right)Compare T86.8402 vs T86.8401 →, T86.8403 — Corneal transplant rejection, bilateral (bilateral)Compare T86.8402 vs T86.8403 →, T86.8409 — Corneal transplant rejection, unspecified eye (unspecified)Compare T86.8402 vs T86.8409 →

Same clinical category (CCSR)

AHRQ's Clinical Classifications Software groups these diagnoses under the same clinical category (Complication of transplanted organs or tissue, initial encounter).

T86.822 — Skin graft (allograft) (autograft) infection, T86.828 — Other complications of skin graft (allograft) (autograft), T86.829 — Unspecified complication of skin graft (allograft) (autograft), T86.830 — Bone graft rejection, T86.831 — Bone graft failure, T86.832 — Bone graft infection, T86.838 — Other complications of bone graft, T86.839 — Unspecified complication of bone graft, T86.840 — Corneal transplant rejection, T86.8401 — Corneal transplant rejection, right eye, T86.8403 — Corneal transplant rejection, bilateral, T86.8409 — Corneal transplant rejection, unspecified eye, T86.841 — Corneal transplant failure, T86.8411 — Corneal transplant failure, right eye, T86.8412 — Corneal transplant failure, left eye, T86.8413 — Corneal transplant failure, bilateral, T86.8419 — Corneal transplant failure, unspecified eye, T86.842 — Corneal transplant infection, T86.8421 — Corneal transplant infection, right eye, T86.8422 — Corneal transplant infection, left eye, +76 more

Same Index main term, other category

The ICD-10-CM Index to Diseases and Injuries files this code under the main term “Rejection”; these codes share that main term but sit in a different category of the Tabular List.

F50.89 — Other specified eating disorder

Lab tests where this diagnosis supports Medicare coverage (NCD)

Medicare's National Coverage Determination (NCD) program lists this diagnosis as medical justification for these lab tests.

Partial Thromboplastin Time (PTT) Test, Prothrombin Time Test and INR (PT/INR)

Contextual Map

Every relationship of T86.8402 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Run T86.8402 with these 14 related codes in Claim Check

Hierarchy

• S00-T88 — Chapter 19: Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88) (S00-T88)[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• T80-T88 — Complications of surgical and medical care, not elsewhere classified[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2026

Referenced by Excludes1 notes

• T88.7 — Unspecified adverse effect of drug or medicament[Excludes1](via T86.-): “specified adverse effects of drugs and medicaments (A00-R94 and T80-T88.6, T88.8)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• Z98.85 — Transplanted organ removal status[Excludes1](via T86.-): “encounter for removal of transplanted organ -code to complication of transplanted organ (T86.-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026

Referenced by Excludes2 notes (9)

• D89 — Other disorders involving the immune mechanism, not elsewhere classified[Excludes2](via T86.-): “transplant failure and rejection (T86.-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• T78 — Adverse effects, not elsewhere classified[Excludes2](via T86.-): “complications of surgical and medical care NEC (T80-T88)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• T79 — Certain early complications of trauma, not elsewhere classified[Excludes2](via T86.-): “complications occurring during or following medical procedures (T80-T88)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• T81 — Complications of procedures, not elsewhere classified[Excludes2](via T86.-): “complications of transplanted organs and tissue (T86.-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• T82 — Complications of cardiac and vascular prosthetic devices, implants and grafts[Excludes2](via T86.-): “failure and rejection of transplanted organs and tissue (T86.-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• T83 — Complications of genitourinary prosthetic devices, implants and grafts[Excludes2](via T86.-): “failure and rejection of transplanted organs and tissue (T86.-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• T84 — Complications of internal orthopedic prosthetic devices, implants and grafts[Excludes2](via T86.-): “failure and rejection of transplanted organs and tissues (T86.-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• T85 — Complications of other internal prosthetic devices, implants and grafts[Excludes2](via T86.-): “failure and rejection of transplanted organs and tissue (T86.-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• and 1 more

Referenced by Code First instructions

• C80.2 — Malignant neoplasm associated with transplanted organ[Code First](via T86.-): “complication of transplanted organ (T86.-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• D47.Z1 — Post-transplant lymphoproliferative disorder (PTLD)[Code First](via T86.-): “complications of transplanted organs and tissue (T86.-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• D89.81 — Graft-versus-host disease[Code First](via T86.-): “complications of transplanted organs and tissue (T86.-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• D89.83 — Cytokine release syndrome[Code First](via T86.-): “complications of transplanted organs and tissue (T86.-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026

Clinical classification (CCSR)

• INJ036 — Complication of transplanted organs or tissue, initial encounter[CCSR]— AHRQ CCSR for ICD-10-CM Diagnoses (HCUP)

MS-DRG Grouper

• CC — Complication or Comorbidity [MS-DRG severity]: “As a secondary diagnosis this code can raise the stay's MS-DRG severity tier (CC).”— CMS MS-DRG Definitions Manual (Appendix C) · FY2026
• DRG 124 — OTHER DISORDERS OF THE EYE WITH MCC OR THROMBOLYTIC AGENT[MS-DRG]: “OTHER DISORDERS OF THE EYE WITH MCC OR THROMBOLYTIC AGENT (MDC 02)”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026
• DRG 125 — OTHER DISORDERS OF THE EYE WITHOUT MCC[MS-DRG]: “OTHER DISORDERS OF THE EYE WITHOUT MCC (MDC 02)”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026

MDC crossing

• MDC 02 — Diseases and Disorders of the Eye[MDC crossing]: “Diseases and Disorders of the Eye — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs. 1,200 same-MDC procedures group here; browse them on the MDC page.”— CMS MS-DRG Definitions Manual · FY2026

Nearest codes (40)

• T86 — Complications of transplanted organs and tissue[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• T86.810 — Lung transplant rejection[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• T86.811 — Lung transplant failure[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• T86.812 — Lung transplant infection[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• T86.818 — Other complications of lung transplant[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• T86.819 — Unspecified complication of lung transplant[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• T86.82 — Complications of skin graft (allograft) (autograft)[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• T86.820 — Skin graft (allograft) rejection[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• and 32 more

Change history

• FY2021 — Added to the code set[Change history]— CMS release files (code change ledger) · icd10cm-fy2021

Relevant guides

• Transplant Complication or Transplant Status? T86 vs Z94, and CKD After a Kidney Transplant →

Sources for this page

Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.

Code, title, tabular notes and index terms Official source data

CMS/CDC ICD-10-CM FY2026 tabular list, index and tables, effective October 1, 2025 Release, file and checksum · Publisher’s page

Coding guidelines Official source data

ICD-10-CM Official Guidelines for Coding and Reporting (FY2026), quoted by section Release, file and checksum · Publisher’s page

Claim edits Official source data

CMS Definitions of Medicare Code Edits — v43.1 (April 2026) Release, file and checksum · Publisher’s page

Inpatient payment groups Official source data

CMS MS-DRG Definitions Manual (incl. Appendix B diagnosis index, Appendix C CC/MCC list, Appendix E procedure index) and IPPS Final Rule tables — v43 Release, file and checksum · Publisher’s page

Change history and date-of-service validity Official source data

CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page

Comparisons, relationships and the contextual map MedCoder structured relationship

Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears

Summary and FAQ answers MedCoder explanation

Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.

Labels on this page: Official source data · MedCoder structured relationship · MedCoder explanation. How to read the labels · All data sources and release dates

Nearest Codes in This Family

Official ICD-10-CM classifications closest to T86.8402 in its code family, with their registry titles.

• T86.838 — Other complications of bone graft
• T86.839 — Unspecified complication of bone graft
• T86.84 — Complications of corneal transplant
• T86.840 — Corneal transplant rejection
• T86.8401 — Corneal transplant rejection, right eye
• T86.8403 — Corneal transplant rejection, bilateral
• T86.8409 — Corneal transplant rejection, unspecified eye
• T86.841 — Corneal transplant failure
• T86.8411 — Corneal transplant failure, right eye
• T86.8412 — Corneal transplant failure, left eye

View all codes in the T86 family