545
CONNECTIVE TISSUE DISORDERS WITH MCC
MS-DRG 545 groups Medicare inpatient hospital stays for: CONNECTIVE TISSUE DISORDERS WITH MCC. This is a medical MS-DRG. It falls under MDC 08 (Diseases and Disorders of the Musculoskeletal System and Connective Tissue).
Payment & Classification Data
Official CMS values from the current fiscal year's IPPS Final Rule.
| Major Diagnostic Category | MDC 08 — Diseases and Disorders of the Musculoskeletal System and Connective Tissue |
| DRG Type | Medical |
| Severity Level | MCC |
| Relative Weight | 2.4817 |
| Relative Weight (10% Cap Applied) | 2.4817 |
| Geometric Mean Length of Stay | 5.5 days |
| Arithmetic Mean Length of Stay | 8.3 days |
| Post-Acute Transfer DRG | Yes |
| Special Pay Transfer DRG | No |
Defining Codes (FY2026)
561 diagnosis codes can drive assignment here: D89.82, E85.0, E85.1, E85.2, E85.3, E85.4, E85.81, E85.82, E85.89, E85.9, G72.41, G72.49 and 549 more.
From the CMS MS-DRG Definitions Manual (Appendices B and E). Assignment also depends on severity, discharge status and the rest of the claim.
Contextual Map
Every relationship of 545 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.
Major Diagnostic Category
- MDC 08 — Diseases and Disorders of the Musculoskeletal System and Connective Tissue [MDC]
Defining diagnoses (561)
- D89.82 — Autoimmune lymphoproliferative syndrome [ALPS] [Grouper diagnosis]
- E85.0 — Non-neuropathic heredofamilial amyloidosis [Grouper diagnosis]
- E85.1 — Neuropathic heredofamilial amyloidosis [Grouper diagnosis]
- E85.2 — Heredofamilial amyloidosis, unspecified [Grouper diagnosis]
- E85.3 — Secondary systemic amyloidosis [Grouper diagnosis]
- E85.4 — Organ-limited amyloidosis [Grouper diagnosis]
- E85.81 — Light chain (AL) amyloidosis [Grouper diagnosis]
- E85.82 — Wild-type transthyretin-related (ATTR) amyloidosis [Grouper diagnosis]
- and 553 more
DRG family
- DRG 546 — CONNECTIVE TISSUE DISORDERS WITH CC [DRG family]: “CONNECTIVE TISSUE DISORDERS WITH CC — same CMS DRG family (545-547), split by severity.”
- DRG 547 — CONNECTIVE TISSUE DISORDERS WITHOUT CC/MCC [DRG family]: “CONNECTIVE TISSUE DISORDERS WITHOUT CC/MCC — same CMS DRG family (545-547), split by severity.”