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Alka-Seltzer Plus Severe Cold PowerFast Fizz Non Drowsy

NDC 0280-0024 · Bayer HealthCare LLC.

Generic nameasprin, dextromethorphan hydrobromide, phenylephrine bitartrate
Dosage formTABLET, EFFERVESCENT
RouteORAL
Active ingredient(s)ASPIRIN, PHENYLEPHRINE BITARTRATE, DEXTROMETHORPHAN HYDROBROMIDE
Strength325; 10; 7.8 mg/1; mg/1; mg/1
Pharmacologic classAdrenergic alpha1-Agonists [MoA], Anti-Inflammatory Agents, Non-Steroidal [CS], Cyclooxygenase Inhibitors [MoA], Decreased Platelet Aggregation [PE], Decreased Prostaglandin Production [PE], Nonsteroidal Anti-inflammatory Drug [EPC], Platelet Aggregation Inhibitor [EPC], Sigma-1 Agonist [EPC], Sigma-1 Receptor Agonists [MoA], Uncompetitive N-methyl-D-aspartate Receptor Antagonist [EPC], Uncompetitive NMDA Receptor Antagonists [MoA], alpha-1 Adrenergic Agonist [EPC]
Marketing categoryOTC MONOGRAPH DRUG

Packages

0280-0024-01 — 10 POUCH in 1 CARTON (0280-0024-01) / 2 TABLET, EFFERVESCENT in 1 POUCH

0280-0024-02 — 24 POUCH in 1 CARTON (0280-0024-02) / 2 TABLET, EFFERVESCENT in 1 POUCH

Related Codes

Same active ingredient

FDA lists these products with the same active ingredient.

0113-6019 — brompheniramine maleate, dextromethorphan hydrobromide, 0113-7019 — acetaminophen, dextromethorphan hydrobromide, 0116-4024 — Promethazine Hydrochloride and Dextromethorphan Hydrobromide, 0121-0933 — Brompheniramine Maleate, Pseudoephedrine Hydrochloride, and Dextromethorphan Hydrobromide, 0121-1070 — Promethazine Hydrochloride and Dextromethorphan Hydrobromide, 0135-7033 — acetaminophen, dextromethorphan HBr, 0135-7034 — acetaminophen, chlorpheniramine maleate, dextromethorphan HBr, 0280-0020 — aspirin, chlorpheniramine maleate, phenylephrine bitartrate, 0280-0021 — aspirin, dextromethorphan hydrobromide, doxylamine succinate, phenylephrine bitartrate, 0280-0023 — aspirin, chlorpheniramine maleate, dextromethorphan hydrobromide, phenylephrine bitartrate, 0280-0055 — chlorpheniramine maleate, dextromethorphan hydrobromide, acetaminophen, phenylephrine hydrochloride, 0280-0060 — aspirin, chlorpheniramine maleate, phenylephrine bitartrate, 0280-0061 — acetaminophen, dextromethorphan hydrobromide, guaifenesin, phenylephrine hydrochloride, 0280-0064 — Aspirin and caffeine, 0280-0068 — aspirin, doxylamine succinate, dextromethorphan hydrobromide, phenylephrine bitartrate, 0280-0084 — ANHYDROUS CITRIC ACID, ASPIRIN, and SODIUM BICARBONATE, 0280-0087 — Alka-Seltzer Original Flavor, 0280-0088 — chlorpheniramine maleate, acetaminophen, phenylephrine hydrochloride, dextromethorphan hydrobromide, 0280-0089 — dextromethorphan hydrobromide, guaifenesin, 0280-0092 — Acetaminophen, Chlorpheniramine malaeate, Dextromethorphan hydrobromide, Phenylephrine hydrochloride, +2694 more

From the FDA National Drug Code Directory, retrieved August 24, 2026. Product listings are submitted by labelers; FDA does not verify them.

Read from: FDA National Drug Code Directory, product.txt and package.txt (accessdata.fda.gov/cder/ndctext.zip) — Snapshot retrieved 2026-08-24, loaded 2026-08-24; CMS Medicare Part B Drug Average Sales Price (ASP) Pricing Files (cms.gov/medicare/payment/part-b-drugs/asp-pricing-files) -- the NDC-HCPCS crosswalk and Part B payment limit files — 2026 Q3 (July 2026 release). All data sources · How to read the labels