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Adult Cough and Chest Congestion Relief DM

NDC 21130-385 · Safeway, Inc.

Generic nameDextromethorphan HBr, Guaifenesin
Dosage formLIQUID
RouteORAL
Active ingredient(s)DEXTROMETHORPHAN HYDROBROMIDE, GUAIFENESIN
Strength20; 200 mg/10mL; mg/10mL
Pharmacologic classDecreased Respiratory Secretion Viscosity [PE], Expectorant [EPC], Increased Respiratory Secretions [PE], Sigma-1 Agonist [EPC], Sigma-1 Receptor Agonists [MoA], Uncompetitive N-methyl-D-aspartate Receptor Antagonist [EPC], Uncompetitive NMDA Receptor Antagonists [MoA]
Marketing categoryOTC MONOGRAPH DRUG

Packages

21130-385-04 — 1 BOTTLE, PLASTIC in 1 BOX (21130-385-04) / 118 mL in 1 BOTTLE, PLASTIC

21130-385-08 — 1 BOTTLE, PLASTIC in 1 BOX (21130-385-08) / 237 mL in 1 BOTTLE, PLASTIC

Related Codes

Same active ingredient

FDA lists these products with the same active ingredient.

17856-6312 — dextromethorphan polistirex, 21130-012 — dextromethorphan polistirex, 21130-036 — Acetaminophen, Dextromethorphan HBr, Guaifenesin, Phenylephrine HCl, 21130-044 — Acetaminophen, Dextromethorphan Hydrobromide, Doxylamine Succinate, 21130-091 — acetaminophen, dextromethorphan hbr, guaifenesin, phenylephrine hcl, 21130-129 — Acetaminophen, Dextromethorphan HBr, Doxylamine Succinate, Phenylephrine HCl, 21130-162 — Dextromethorphan Hydrobromide, Guaifenesin, and Phenylephrine Hydrochloride, 21130-179 — Guaifenesin, 21130-343 — Acetaminophen, Dextromethorphan Hydrobromide, Doxylamine Succinate, 21130-378 — Dextromethorphan HBr, Phenylephrine HCl, 21130-399 — Guaifenesin, 21130-436 — acetaminophen, dextromethorphan hbr, guaifenesin, phenylephrine hcl, 21130-454 — dextromethorphan hydrobromide, guaifenesin, 21130-499 — Dextromethorphan Hydrobromide, Doxylamine Succinate, 21130-505 — Dextromethorphan HBr, Guaifenesin, 21130-520 — dextromethorphan polistirex, 21130-538 — dextromethorphan polistirex, 21130-554 — Guaifenesin, 21130-580 — Acetaminophen Dextromethorphan HBr Phenylephrine HCl, 21130-583 — Dextromethorphan HBr, Guaifenesin, +2508 more

Read from: FDA National Drug Code Directory, product.txt and package.txt (accessdata.fda.gov/cder/ndctext.zip) — Snapshot retrieved 2026-08-24, loaded 2026-08-24; CMS Medicare Part B Drug Average Sales Price (ASP) Pricing Files (cms.gov/medicare/payment/part-b-drugs/asp-pricing-files) -- the NDC-HCPCS crosswalk and Part B payment limit files — 2026 Q3 (July 2026 release). All data sources · How to read the labels