Skip to main content
Compare/D57 vs D58

D57 vs D58

D57 (Sickle-cell disorders) compared with D58 (Other hereditary hemolytic anemias), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.

Can these codes be reported together?

No — do not report together. D57 carries an Excludes1 note covering D58: “other hemoglobinopathies (D58.-)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Side by side

D57Sickle-cell disordersD58Other hereditary hemolytic anemias
Billing statusNon-billable header

Report instead: D57.00, D57.01, D57.02, D57.03, D57.04

Non-billable header

Report instead: D58.0, D58.1, D58.2, D58.8, D58.9

ClassificationD50-D89 — Diseases of the Blood and Blood-forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89)D50-D89 — Diseases of the Blood and Blood-forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89)
DefinitionSickle-cell disorders is a non-billable ICD-10-CM category code (D57).Other hereditary hemolytic anemias is a non-billable ICD-10-CM category code (D58).
Use additional code
code for any associated fever (R50.81)

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources