D57.00 is the authoritative medical code for Hb-SS disease with crisis, unspecified. This classification is used in medical billing and clinical recording to specify the clinical criteria for hb-ss disease with crisis, unspecified (ICD-10-CM D57.00), ensuring healthcare documentation aligns with 2026 federal coding standards.
Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.
Official Registry Overview & Definition
Hb-SS disease with crisis, unspecified is a billable ICD-10-CM diagnosis code D57.00. Inclusion terms: Hb-SS disease with painful crisis NOS; Hb-SS disease with (vaso-occlusive) pain NOS. Excludes1 (not coded here): other hemoglobinopathies D58.-. Use additional code: code for any associated fever R50.81.
Official Tabular Instructional Notes
Sequencing, inclusion, and exclusion notes published for D57.00 in the official ICD-10-CM tabular list.
Inclusion Terms
Alternative terms the tabular list files under this code.
- Hb-SS disease with painful crisis NOS
- Hb-SS disease with (vaso-occlusive) pain NOS
Excludes1 — Not Coded Here
Conditions that can never be reported with this code; the two are mutually exclusive.
- other hemoglobinopathies D58.-
Use Additional Code
Supplementary codes the tabular list directs you to add.
- code for any associated fever R50.81
Frequently Asked Questions (FAQ) & Clinical Guidance
What can't be coded together with D57.00?
Per Excludes1 instructions, D57.00 must not be reported with: other hemoglobinopathies (D58.-).
Is an additional code needed with D57.00?
Use additional code(s) to specify: code for any associated fever (R50.81).
What conditions are included under D57.00?
Hb-SS disease with crisis, unspecified includes: Hb-SS disease with (painful) crisis NOS; Hb-SS disease with (vaso-occlusive) pain NOS.
Codes in This Family (40)
Official ICD-10-CM classifications in the same code family as D57.00, with their registry titles.
- D57 — Sickle-cell disorders
- D57.0 — Hb-SS disease with crisis
- D57.01 — Hb-SS disease with acute chest syndrome
- D57.02 — Hb-SS disease with splenic sequestration
- D57.03 — Hb-SS disease with cerebral vascular involvement
- D57.04 — Hb-SS disease with dactylitis
- D57.09 — Hb-SS disease with crisis with other specified complication
- D57.1 — Sickle-cell disease without crisis
- D57.2 — Sickle-cell/Hb-C disease
- D57.20 — Sickle-cell/Hb-C disease without crisis
- D57.21 — Sickle-cell/Hb-C disease with crisis
- D57.211 — Sickle-cell/Hb-C disease with acute chest syndrome
- D57.212 — Sickle-cell/Hb-C disease with splenic sequestration
- D57.213 — Sickle-cell/Hb-C disease with cerebral vascular involvement
- D57.214 — Sickle-cell/Hb-C disease with dactylitis
- D57.218 — Sickle-cell/Hb-C disease with crisis with other specified complication
- D57.219 — Sickle-cell/Hb-C disease with crisis, unspecified
- D57.3 — Sickle-cell trait
- D57.4 — Sickle-cell thalassemia
- D57.40 — Sickle-cell thalassemia without crisis
- D57.41 — Sickle-cell thalassemia, unspecified, with crisis
- D57.411 — Sickle-cell thalassemia, unspecified, with acute chest syndrome
- D57.412 — Sickle-cell thalassemia, unspecified, with splenic sequestration
- D57.413 — Sickle-cell thalassemia, unspecified, with cerebral vascular involvement
- D57.414 — Sickle-cell thalassemia, unspecified, with dactylitis
- D57.418 — Sickle-cell thalassemia, unspecified, with crisis with other specified complication
- D57.419 — Sickle-cell thalassemia, unspecified, with crisis
- D57.42 — Sickle-cell thalassemia beta zero without crisis
- D57.43 — Sickle-cell thalassemia beta zero with crisis
- D57.431 — Sickle-cell thalassemia beta zero with acute chest syndrome
- D57.432 — Sickle-cell thalassemia beta zero with splenic sequestration
- D57.433 — Sickle-cell thalassemia beta zero with cerebral vascular involvement
- D57.434 — Sickle-cell thalassemia beta zero with dactylitis
- D57.438 — Sickle-cell thalassemia beta zero with crisis with other specified complication
- D57.439 — Sickle-cell thalassemia beta zero with crisis, unspecified
- D57.44 — Sickle-cell thalassemia beta plus without crisis
- D57.45 — Sickle-cell thalassemia beta plus with crisis
- D57.451 — Sickle-cell thalassemia beta plus with acute chest syndrome
- D57.452 — Sickle-cell thalassemia beta plus with splenic sequestration
- D57.453 — Sickle-cell thalassemia beta plus with cerebral vascular involvement
Indexed Clinical Terms (6)
Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code.
- Crisis, sickle-cell
- Crisis, sickle-cell, with, pain (vaso-occlusive)
- Disease, diseased, hemoglobin or Hb, S or SS, with, crisis (painful)
- Disease, diseased, hemoglobin or Hb, S or SS, with, pain (vaso-occlusive)
- Disease, diseased, sickle-cell, with, crisis (painful)
- Disease, diseased, sickle-cell, with, pain (vaso-occlusive)
Related Codes & Numerical Sequence (Crawl Map)
Search engines and indexers are advised to traverse adjacent medical codes in this sub-chapter range to find correlated diagnoses or therapeutic procedures: