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E16.A3 ICD-10-CM Code: Hypoglycemia level 3

Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.

Coding at a Glance

Tabular directives
1 inclusion term

Inpatient Payment Groups (MS-DRG)

Potential MS-DRG participation — not a DRG assignment.

MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v43, Appendix B.

  • MS-DRG 643 — ENDOCRINE DISORDERS WITH MCC (MDC 10)
  • MS-DRG 644 — ENDOCRINE DISORDERS WITH CC (MDC 10)
  • MS-DRG 645 — ENDOCRINE DISORDERS WITHOUT CC/MCC (MDC 10)

A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.

Coding instructions

Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for E16.A3 in the official ICD-10-CM tabular list, quoted as published.

Source: CMS/CDC — ICD-10-CM Tabular ListRelease: FY2026Effective: October 1, 2025

Inclusion Terms

Alternative terms the tabular list files under this code.

  • Decreased blood glucose level 3

Code Overview

Hypoglycemia level 3 is a billable ICD-10-CM diagnosis code (E16.A3).

MedCoder summary Summary composed by MedCoder from this code's official ICD-10-CM record. The tabular instructional notes themselves appear verbatim below.

Indexed Clinical Terms (2)

Official source data — entries quoted as published, in the Index’s own lookup phrasing

Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code. These are alphabetic-index entries shown as the Index writes them — lookup phrasing, not necessarily the wording of a final diagnosis.

Verify Before Coding

  • No Medicare Code Editor or MS-DRG Definitions Manual restrictions apply to this code.

From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.

Relationships & Classification

MedCoder structured relationships — computed from published CMS and AHRQ datasets

Other codes that name E16.A3 or its code family, from the CMS ICD-10-CM tabular instructional notes. Tabular-note edges are stored at the code family level that carries each note.

Referenced by 1 Code First instruction: G63 — Polyneuropathy in diseases classified elsewhere (via E16.-).

Each of these codes carries a Code First note naming this condition — when that code is reported, THIS code is sequenced first, ahead of it.

Referenced by 9 Use Additional Code instructions: E08.64 — Diabetes mellitus due to underlying condition with hypoglycemia (via E16.A.-), E09.64 — Drug or chemical induced diabetes mellitus with hypoglycemia (via E16.A.-), E10.64 — Type 1 diabetes mellitus with hypoglycemia (via E16.A.-), E11.64 — Type 2 diabetes mellitus with hypoglycemia (via E16.A.-), E13.64 — Other specified diabetes mellitus with hypoglycemia (via E16.A.-), E16.0 — Drug-induced hypoglycemia without coma (via E16.A.-), E16.1 — Other hypoglycemia (via E16.A.-), E16.2 — Hypoglycemia, unspecified (via E16.A.-), E89.83 — Postprocedural hypoglycemia following a procedure (via E16.A.-).

These codes instruct coders to additionally report this code when it applies.

MS-DRG Grouper Relationships (FY2026)

Potential MS-DRG participation — not a DRG assignment.

FY2026 MS-DRG: not on the CMS CC/MCC list — as a secondary diagnosis this code does not change MS-DRG severity for that release.

Named in the grouper logic of 3 MS-DRGs: DRG 643 (MDC 10), DRG 644 (MDC 10), DRG 645 (MDC 10).

From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.

Clinical classification (AHRQ CCSR):END015 — Other specified and unspecified endocrine disorders (default).

Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.

Related Codes

Same clinical category (CCSR)

AHRQ's Clinical Classifications Software groups these diagnoses under the same clinical category (Other specified and unspecified endocrine disorders).

E15 — Nondiabetic hypoglycemic coma, E16.0 — Drug-induced hypoglycemia without coma, E16.1 — Other hypoglycemia, E16.2 — Hypoglycemia, unspecified, E16.3 — Increased secretion of glucagon, E16.4 — Increased secretion of gastrin, E16.8 — Other specified disorders of pancreatic internal secretion, E16.9 — Disorder of pancreatic internal secretion, unspecified, E16.A1 — Hypoglycemia level 1, E16.A2 — Hypoglycemia level 2, E20.0 — Idiopathic hypoparathyroidism, E20.1 — Pseudohypoparathyroidism, E20.8 — Other hypoparathyroidism, E20.810 — Autosomal dominant hypocalcemia, E20.811 — Secondary hypoparathyroidism in diseases classified elsewhere, E20.812 — Autoimmune hypoparathyroidism, E20.818 — Other specified hypoparathyroidism due to impaired parathyroid hormone secretion, E20.819 — Hypoparathyroidism due to impaired parathyroid hormone secretion, unspecified, E20.89 — Other specified hypoparathyroidism, E20.9 — Hypoparathyroidism, unspecified, +83 more

Same Index main term, other category

The ICD-10-CM Index to Diseases and Injuries files this code under the main terms “Decrease”, “Hypoglycemia”; these codes share that main term but sit in a different category of the Tabular List.

D58.8 — Other specified hereditary hemolytic anemias (fragility of erythrocytes), D69.6 — Thrombocytopenia, unspecified (platelets), D72.810 — Lymphocytopenia (lymphocytes), D72.818 — Other decreased white blood cell count (leukocytes, specified NEC), D72.819 — Decreased white blood cell count, unspecified (leukocytes), E15 — Nondiabetic hypoglycemic coma (coma), E23.0 — Hypopituitarism (function, pituitary), E28.39 — Other primary ovarian failure (estrogen), E71.19 — Other disorders of branched-chain amino-acid metabolism (leucine-induced), E87.8 — Other disorders of electrolyte and fluid balance, not elsewhere classified (tolerance, salt and water), E89.40 — Asymptomatic postprocedural ovarian failure (estrogen, postablative), E89.41 — Symptomatic postprocedural ovarian failure (estrogen, postablative, symptomatic), E89.830 — Post bariatric hypoglycemia (post bariatric), E89.838 — Other postprocedural hypoglycemia (postprocedural), H54.7 — Unspecified visual loss (vision NEC), K86.89 — Other specified diseases of pancreas (function, parenchyma of pancreas), K90.3 — Pancreatic steatorrhea (function, lipase), K90.49 — Malabsorption due to intolerance, not elsewhere classified (tolerance, fat), P70.0 — Syndrome of infant of mother with gestational diabetes (in infant of diabetic mother, gestational diabetes), P70.1 — Syndrome of infant of a diabetic mother (in infant of diabetic mother), +10 more

Lab tests where this diagnosis supports Medicare coverage (NCD)

Medicare's National Coverage Determination (NCD) program lists this diagnosis as medical justification for these lab tests.

HbA1c Test (Glycated Hemoglobin), Blood Glucose Test

Contextual Map

Every relationship of E16.A3 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Run E16.A3 with these 9 related codes in Claim Check

Hierarchy

Referenced by Code First instructions

Referenced by Use Additional Code instructions (9)

Clinical classification (CCSR)

MS-DRG Grouper

MDC crossing

  • MDC 10 — Endocrine, Nutritional and Metabolic Diseases and Disorders[MDC crossing]: “Endocrine, Nutritional and Metabolic Diseases and Disorders — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs. 5,008 same-MDC procedures group here; browse them on the MDC page.”— CMS MS-DRG Definitions Manual · FY2026

Index entries

  • Decrease (d), blood, glucose, level 3[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
  • Hypoglycemia (spontaneous), level, 3[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026

Nearest codes (11)

Change history

Sources for this page

Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.

Code, title, tabular notes and index terms Official source data
CMS/CDC ICD-10-CM FY2026 tabular list, index and tables, effective October 1, 2025 Release, file and checksum · Publisher’s page
Claim edits Official source data
CMS Definitions of Medicare Code Edits — v43.1 (April 2026) Release, file and checksum · Publisher’s page
Inpatient payment groups Official source data
CMS MS-DRG Definitions Manual (incl. Appendix B diagnosis index, Appendix C CC/MCC list, Appendix E procedure index) and IPPS Final Rule tables — v43 Release, file and checksum · Publisher’s page
Change history and date-of-service validity Official source data
CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page
Comparisons, relationships and the contextual map MedCoder structured relationship
Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears
Summary and FAQ answers MedCoder explanation
Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.

Labels on this page: Official source data · MedCoder structured relationship · MedCoder explanation. How to read the labels · All data sources and release dates

Cite this page

Reference this page in a research guide, syllabus or article. The release is included because code content changes each year.

MedCoder.ai. "E16.A3 — Hypoglycemia level 3." ICD-10-CM FY2026. https://medcoder.ai/icd10/code/e16.a3-hypoglycemia-level-3

Change history

  • FY2025 — October 1, 2024
    Added to the code set
    Hypoglycemia level 3
    FY2025 changes

Nearest Codes in This Family

Official ICD-10-CM classifications closest to E16.A3 in its code family, with their registry titles.

View all codes in the E16 family