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E89.6 ICD-10-CM Code: Postprocedural adrenocortical (-medullary) hypofunction

Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.

Coding at a Glance

Tabular directives
1 Excludes2
Risk adjustment
CMS-HCC V22 category 23 · RxHCC V08 category 43

Inpatient Payment Groups (MS-DRG)

Potential MS-DRG participation — not a DRG assignment.

MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v43, Appendix B.

  • MS-DRG 643 — ENDOCRINE DISORDERS WITH MCC (MDC 10)
  • MS-DRG 644 — ENDOCRINE DISORDERS WITH CC (MDC 10)
  • MS-DRG 645 — ENDOCRINE DISORDERS WITHOUT CC/MCC (MDC 10)

A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.

Coding instructions

Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for E89.6 in the official ICD-10-CM tabular list, quoted as published.

Source: CMS/CDC — ICD-10-CM Tabular ListRelease: FY2026Effective: October 1, 2025

Notes without a marker are published on E89.6 itself; “inherited from” names the category or block whose note applies here.

Excludes2 — Not Included Here

Conditions not covered by this code, but which may be reported alongside it when both are present.

Source: inherited from E89

Coder workflow for E89.6

MedCoder structured workflow — derived from this code’s own official record

Documentation check

The provider’s diagnostic statement
Codes are assigned from the provider’s documented diagnosis, not from clinical criteria, test values or a medication list (Guidelines I.A.19).

Official instructions as workflow

  • Excludes2 — not part of E89.6(1 note)

    Coding workflow: The conditions named in this note are not included in E89.6. When the record documents both, both may be reported; the note is a boundary, not a prohibition.

    CompareE36.0, E36.1, E36.8

    See the official tabular notes · Guidelines I.A.12.b

Every row is derived from this code’s own record — its title, tabular notes, 7th-character family and same-category siblings — with fixed MedCoder wording; nothing is inferred about a patient. The official notes and guideline text are in the sections each row links to, and they control.

Code Overview

Postprocedural adrenocortical (-medullary) hypofunction is a billable ICD-10-CM diagnosis code (E89.6).

MedCoder summary Summary composed by MedCoder from this code's official ICD-10-CM record. The tabular instructional notes themselves appear verbatim below.

Indexed Clinical Terms (5)

Official source data — entries quoted as published, in the Index’s own lookup phrasing

Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code. These are alphabetic-index entries shown as the Index writes them — lookup phrasing, not necessarily the wording of a final diagnosis.

Verify Before Coding

  • CC as a secondary diagnosis (FY2026). Can raise the stay's MS-DRG severity tier.

From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.

Relationships & Classification

MedCoder structured relationships — computed from published CMS and AHRQ datasets

Other codes that name E89.6 or its code family, from the CMS ICD-10-CM tabular instructional notes. Tabular-note edges are stored at the code family level that carries each note.

Referenced by 12 Excludes2 notes across 3 chapters: E36 — Intraoperative complications of endocrine system (via E89.-), T80 — Complications following infusion, transfusion and therapeutic injection (via E89.-), T80-T88 — Complications of surgical and medical care, not elsewhere classified (T80-T88) (via E89.-), T81 — Complications of procedures, not elsewhere classified (via E89.-), T82 — Complications of cardiac and vascular prosthetic devices, implants and grafts (via E89.-), T83 — Complications of genitourinary prosthetic devices, implants and grafts (via E89.-), T84 — Complications of internal orthopedic prosthetic devices, implants and grafts (via E89.-), T85 — Complications of other internal prosthetic devices, implants and grafts (via E89.-), T86 — Complications of transplanted organs and tissue (via E89.-), T87 — Complications peculiar to reattachment and amputation (via E89.-), T88 — Other complications of surgical and medical care, not elsewhere classified (via E89.-), Z90 — Acquired absence of organs, not elsewhere classified (via E89.-).

These codes’ tabular lists name this diagnosis as distinct — both may be reported when both are documented.

MS-DRG Grouper Relationships (FY2026)

Potential MS-DRG participation — not a DRG assignment.

FY2026 MS-DRG: CC — Complication or Comorbidity. Reported as a secondary diagnosis, this code raises the stay's MS-DRG severity tier — except when the principal diagnosis is one of 22 clinically related codes on its CMS exclusion list.

Named in the grouper logic of 3 MS-DRGs: DRG 643 (MDC 10), DRG 644 (MDC 10), DRG 645 (MDC 10).

From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.

Clinical classification (AHRQ CCSR):END014 — Postprocedural or postoperative endocrine or metabolic complication (default).

Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.

Related Codes

Same clinical process (MS-DRG)

Acts as CC — raises the severity of other admissions. CMS groups these diagnoses into one MS-DRG principal-diagnosis exclusion process — a CC/MCC on this list never raises severity when the principal diagnosis is also on it.

A18.7 — Tuberculosis of adrenal glands, A18.82 — Tuberculosis of other endocrine glands, A18.84 — Tuberculosis of heart, A18.89 — Tuberculosis of other sites, E27.0 — Other adrenocortical overactivity, E27.1 — Primary adrenocortical insufficiency, E27.2 — Addisonian crisis, E27.3 — Drug-induced adrenocortical insufficiency, E27.40 — Unspecified adrenocortical insufficiency, E27.49 — Other adrenocortical insufficiency, E27.5 — Adrenomedullary hyperfunction, E27.8 — Other specified disorders of adrenal gland, E27.9 — Disorder of adrenal gland, unspecified, E30.9 — Disorder of puberty, unspecified, E34.1 — Other hypersecretion of intestinal hormones, E34.50 — Androgen insensitivity syndrome, unspecified, E34.51 — Complete androgen insensitivity syndrome, E34.52 — Partial androgen insensitivity syndrome, E34.8 — Other specified endocrine disorders, E34.9 — Endocrine disorder, unspecified, +1 more

Same clinical category (CCSR)

AHRQ's Clinical Classifications Software groups these diagnoses under the same clinical category (Postprocedural or postoperative endocrine or metabolic complication).

E36.01 — Intraoperative hemorrhage and hematoma of an endocrine system organ or structure complicating an endocrine system procedure, E36.02 — Intraoperative hemorrhage and hematoma of an endocrine system organ or structure complicating other procedure, E36.11 — Accidental puncture and laceration of an endocrine system organ or structure during an endocrine system procedure, E36.12 — Accidental puncture and laceration of an endocrine system organ or structure during other procedure, E36.8 — Other intraoperative complications of endocrine system, E89.0 — Postprocedural hypothyroidism, E89.1 — Postprocedural hypoinsulinemia, E89.2 — Postprocedural hypoparathyroidism, E89.3 — Postprocedural hypopituitarism, E89.40 — Asymptomatic postprocedural ovarian failure, E89.41 — Symptomatic postprocedural ovarian failure, E89.5 — Postprocedural testicular hypofunction, E89.810 — Postprocedural hemorrhage of an endocrine system organ or structure following an endocrine system procedure, E89.811 — Postprocedural hemorrhage of an endocrine system organ or structure following other procedure, E89.820 — Postprocedural hematoma of an endocrine system organ or structure following an endocrine system procedure, E89.821 — Postprocedural hematoma of an endocrine system organ or structure following other procedure, E89.822 — Postprocedural seroma of an endocrine system organ or structure following an endocrine system procedure, E89.823 — Postprocedural seroma of an endocrine system organ or structure following other procedure, E89.89 — Other postprocedural endocrine and metabolic complications and disorders

Same Index main term, other category

The ICD-10-CM Index to Diseases and Injuries files this code under the main terms “Status”, “Absence”, “Hypofunction”; these codes share that main term but sit in a different category of the Tabular List.

D80.4 — Selective deficiency of immunoglobulin M [IgM] (immunoglobulin, isolated NEC, IgM), E03.1 — Congenital hypothyroidism without goiter (thyroid, congenital), E23.0 — Hypopituitarism (pituitary), E27.1 — Primary adrenocortical insufficiency (adrenocortical, primary), E27.3 — Drug-induced adrenocortical insufficiency (adrenocortical, drug-induced), E27.40 — Unspecified adrenocortical insufficiency (adrenocortical), E28.39 — Other primary ovarian failure (ovary), E29.1 — Testicular hypofunction (testicular), E32.8 — Other diseases of thymus (thymicus), E88.09 — Other disorders of plasma-protein metabolism, not elsewhere classified (albumin in blood), F07.81 — Postconcussional syndrome (postcommotio cerebri), G40.901 — Epilepsy, unspecified, not intractable, with status epilepticus (epileptic, epilepticus), G80.3 — Athetoid cerebral palsy (marmoratus), H93.8 — Other specified disorders of ear (ear, congenital, acquired), I20.9 — Angina pectoris, unspecified (anginosus), K00.0 — Anodontia (teeth, tooth), K08.101 — Complete loss of teeth, unspecified cause, class I (teeth, tooth, acquired, class I), K08.102 — Complete loss of teeth, unspecified cause, class II (teeth, tooth, acquired, class II), K08.103 — Complete loss of teeth, unspecified cause, class III (teeth, tooth, acquired, class III), K08.104 — Complete loss of teeth, unspecified cause, class IV (teeth, tooth, acquired, class IV), +276 more

Lab tests where this diagnosis supports Medicare coverage (NCD)

Medicare's National Coverage Determination (NCD) program lists this diagnosis as medical justification for these lab tests.

Thyroid Stimulating Hormone (TSH)

Contextual Map

Every relationship of E89.6 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Run E89.6 with these 8 related codes in Claim Check

Hierarchy

Referenced by Excludes2 notes (12)

Clinical classification (CCSR)

MS-DRG Grouper

  • CC — Complication or Comorbidity [MS-DRG severity]: “As a secondary diagnosis this code can raise the stay's MS-DRG severity tier (CC).”— CMS MS-DRG Definitions Manual (Appendix C) · FY2026
  • DRG 643 — ENDOCRINE DISORDERS WITH MCC[MS-DRG]: “ENDOCRINE DISORDERS WITH MCC (MDC 10)”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026
  • DRG 644 — ENDOCRINE DISORDERS WITH CC[MS-DRG]: “ENDOCRINE DISORDERS WITH CC (MDC 10)”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026
  • DRG 645 — ENDOCRINE DISORDERS WITHOUT CC/MCC[MS-DRG]: “ENDOCRINE DISORDERS WITHOUT CC/MCC (MDC 10)”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026

MDC crossing

  • MDC 10 — Endocrine, Nutritional and Metabolic Diseases and Disorders[MDC crossing]: “Endocrine, Nutritional and Metabolic Diseases and Disorders — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs. 5,008 same-MDC procedures group here; browse them on the MDC page.”— CMS MS-DRG Definitions Manual · FY2026

Index entries

  • Absence (of) (organ or part) (complete or partial), adrenal (gland) (congenital), acquired[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
  • Complication (s) (from) (of), endocrine, postprocedural, adrenal hypofunction[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
  • Hypofunction, adrenocortical, postprocedural[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
  • Hypofunction, adrenomedullary, postprocedural[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
  • Status (post), adrenalectomy (unilateral) (bilateral)[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026

Nearest codes (22)

Change history

  • FY2016 — In the code set at ICD-10-CM adoption [Change history]— CMS release files (code change ledger) · icd10cm-fy2016

Sources for this page

Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.

Code, title, tabular notes and index terms Official source data
CMS/CDC ICD-10-CM FY2026 tabular list, index and tables, effective October 1, 2025 Release, file and checksum · Publisher’s page
Claim edits Official source data
CMS Definitions of Medicare Code Edits — v43.1 (April 2026) Release, file and checksum · Publisher’s page
Inpatient payment groups Official source data
CMS MS-DRG Definitions Manual (incl. Appendix B diagnosis index, Appendix C CC/MCC list, Appendix E procedure index) and IPPS Final Rule tables — v43 Release, file and checksum · Publisher’s page
Change history and date-of-service validity Official source data
CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page
Comparisons, relationships and the contextual map MedCoder structured relationship
Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears
Summary and FAQ answers MedCoder explanation
Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.

Labels on this page: Official source data · MedCoder structured relationship · MedCoder explanation. How to read the labels · All data sources and release dates

Cite this page

Reference this page in a research guide, syllabus or article. The release is included because code content changes each year.

MedCoder.ai. "E89.6 — Postprocedural adrenocortical (-medullary) hypofunction." ICD-10-CM FY2026. https://medcoder.ai/icd10/code/e89.6-postprocedural-adrenocortical-medullary-hypofunction

Change history

  • FY2016 — October 1, 2015
    In the code set at ICD-10-CM adoption
    Postprocedural adrenocortical (-medullary) hypofunction

No changes since FY2016 — additions, deletions, description changes and billable-status changes are tracked through FY2027 (effective October 1, 2026), and none are recorded for this code. Note changes are tracked from FY2027 only.

Nearest Codes in This Family

Official ICD-10-CM classifications closest to E89.6 in its code family, with their registry titles.

View all codes in the E89 family