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F43.0 ICD-10-CM Code: Acute stress reaction

Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.

Coding at a Glance

Tabular directives
6 inclusion terms

Inpatient Payment Groups (MS-DRG)

Potential MS-DRG participation — not a DRG assignment.

MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v43, Appendix B.

  • MS-DRG 880 — ACUTE ADJUSTMENT REACTION AND PSYCHOSOCIAL DYSFUNCTION (MDC 19)

A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.

Coding instructions

Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for F43.0 in the official ICD-10-CM tabular list, quoted as published.

Source: CMS/CDC — ICD-10-CM Tabular ListRelease: FY2026Effective: October 1, 2025

Inclusion Terms

Alternative terms the tabular list files under this code.

  • Acute crisis reaction
  • Acute reaction to stress
  • Combat and operational stress reaction
  • Combat fatigue
  • Crisis state
  • Psychic shock

Code Overview

Acute stress reaction is a billable ICD-10-CM diagnosis code (F43.0).

MedCoder summary Summary composed by MedCoder from this code's official ICD-10-CM record. The tabular instructional notes themselves appear verbatim below.

Indexed Clinical Terms (27)

Official source data — entries quoted as published, in the Index’s own lookup phrasing

Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code. These are alphabetic-index entries shown as the Index writes them — lookup phrasing, not necessarily the wording of a final diagnosis.

Verify Before Coding

  • No Medicare Code Editor or MS-DRG Definitions Manual restrictions apply to this code.

From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.

Relationships & Classification

MedCoder structured relationships — computed from published CMS and AHRQ datasets

Other codes that name F43.0 or its code family, from the CMS ICD-10-CM tabular instructional notes. Tabular-note edges are stored at the code family level that carries each note.

Referenced by 2 Excludes1 notes: R53.8 — Other malaise and fatigue, R57 — Shock, not elsewhere classified.

These codes’ tabular lists mark this diagnosis as mutually exclusive — not reported together unless the conditions are documented as unrelated.

Referenced by 2 Excludes2 notes: F41 — Other anxiety disorders, F93.0 — Separation anxiety disorder of childhood (via F43.-).

These codes’ tabular lists name this diagnosis as distinct — both may be reported when both are documented.

MS-DRG Grouper Relationships (FY2026)

Potential MS-DRG participation — not a DRG assignment.

FY2026 MS-DRG: not on the CMS CC/MCC list — as a secondary diagnosis this code does not change MS-DRG severity for that release.

Named in the grouper logic of 1 MS-DRG: DRG 880 (MDC 19).

From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.

Clinical classification (AHRQ CCSR):MBD007 — Trauma- and stressor-related disorders (default).

Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.

Related Codes

Same clinical category (CCSR)

AHRQ's Clinical Classifications Software groups these diagnoses under the same clinical category (Trauma- and stressor-related disorders).

F43.10 — Post-traumatic stress disorder, unspecified, F43.11 — Post-traumatic stress disorder, acute, F43.12 — Post-traumatic stress disorder, chronic, F43.20 — Adjustment disorder, unspecified, F43.21 — Adjustment disorder with depressed mood, F43.22 — Adjustment disorder with anxiety, F43.23 — Adjustment disorder with mixed anxiety and depressed mood, F43.24 — Adjustment disorder with disturbance of conduct, F43.25 — Adjustment disorder with mixed disturbance of emotions and conduct, F43.29 — Adjustment disorder with other symptoms, F43.8 — Other reactions to severe stress, F43.81 — Prolonged grief disorder, F43.89 — Other reactions to severe stress, F43.9 — Reaction to severe stress, unspecified, F44.0 — Dissociative amnesia, F44.1 — Dissociative fugue, F44.2 — Dissociative stupor, F44.4 — Conversion disorder with motor symptom or deficit, F44.5 — Conversion disorder with seizures or convulsions, F44.6 — Conversion disorder with sensory symptom or deficit, +7 more

Same Index main term, other category

The ICD-10-CM Index to Diseases and Injuries files this code under the main terms “Fugue”, “Stupor”, “Disturbance”, …; these codes share that main term but sit in a different category of the Tabular List.

F33.3 — Major depressive disorder, recurrent, severe with psychotic symptoms (reactive, depressive, recurrent), F33.8 — Other recurrent depressive disorders (depressive, recurrent episode), F33.9 — Major depressive disorder, recurrent, unspecified (depressive, affective, recurrent episode), F34.1 — Dysthymic disorder (depressive, neurotic), F40.10 — Social phobia, unspecified (emotions specific to childhood and adolescence, with, shyness), F40.9 — Phobic anxiety disorder, unspecified (phobic), F41.0 — Panic disorder [episodic paroxysmal anxiety], F41.1 — Generalized anxiety disorder (anxiety), F42.2 — Mixed obsessional thoughts and acts (compulsive, mixed with obsessional thoughts), F42.8 — Other obsessive-compulsive disorder (compulsive), F44.1 — Dissociative fugue (hysterical), F44.2 — Dissociative stupor (psychogenic), F44.4 — Conversion disorder with motor symptom or deficit (psychomotor), F44.6 — Conversion disorder with sensory symptom or deficit (sensation NEC, hysterical), F44.89 — Other dissociative and conversion disorders (confusional), F44.9 — Dissociative and conversion disorder, unspecified (dissociative), F45.20 — Hypochondriacal disorder, unspecified (hypochondriacal), F45.8 — Other somatoform disorders (oculogyric, psychogenic), F45.9 — Somatoform disorder, unspecified (psychogenic), F48.1 — Depersonalization-derealization syndrome (neurotic, with depersonalization), +339 more

Contextual Map

Every relationship of F43.0 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Run F43.0 with these 4 related codes in Claim Check

Hierarchy

Referenced by Excludes1 notes

Referenced by Excludes2 notes

Clinical classification (CCSR)

MS-DRG Grouper

MDC crossing

  • MDC 19 — Mental Diseases and Disorders[MDC crossing]: “Mental Diseases and Disorders — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs.”— CMS MS-DRG Definitions Manual · FY2026

Index entries (27)

  • Battle exhaustion[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
  • Combat fatigue[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
  • Crisis, acute reaction[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
  • Crisis, emotional, acute reaction to stress[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
  • Crisis, state (acute reaction)[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
  • Delirium, delirious (acute or subacute) (not alcohol- or drug-induced), exhaustion[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
  • Disorder (of), acute, stress[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
  • Disorder (of), dissociative, brief reactive[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
  • and 19 more

Nearest codes (17)

Change history

  • FY2016 — In the code set at ICD-10-CM adoption [Change history]— CMS release files (code change ledger) · icd10cm-fy2016

Sources for this page

Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.

Code, title, tabular notes and index terms Official source data
CMS/CDC ICD-10-CM FY2026 tabular list, index and tables, effective October 1, 2025 Release, file and checksum · Publisher’s page
Claim edits Official source data
CMS Definitions of Medicare Code Edits — v43.1 (April 2026) Release, file and checksum · Publisher’s page
Inpatient payment groups Official source data
CMS MS-DRG Definitions Manual (incl. Appendix B diagnosis index, Appendix C CC/MCC list, Appendix E procedure index) and IPPS Final Rule tables — v43 Release, file and checksum · Publisher’s page
Change history and date-of-service validity Official source data
CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page
Comparisons, relationships and the contextual map MedCoder structured relationship
Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears
Summary and FAQ answers MedCoder explanation
Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.

Labels on this page: Official source data · MedCoder structured relationship · MedCoder explanation. How to read the labels · All data sources and release dates

Cite this page

Reference this page in a research guide, syllabus or article. The release is included because code content changes each year.

MedCoder.ai. "F43.0 — Acute stress reaction." ICD-10-CM FY2026. https://medcoder.ai/icd10/code/f43.0-acute-stress-reaction

Change history

  • FY2016 — October 1, 2015
    In the code set at ICD-10-CM adoption
    Acute stress reaction

No changes since FY2016 — additions, deletions, description changes and billable-status changes are tracked through FY2027 (effective October 1, 2026), and none are recorded for this code. Note changes are tracked from FY2027 only.

Nearest Codes in This Family

Official ICD-10-CM classifications closest to F43.0 in its code family, with their registry titles.

View all codes in the F43 family