G31.82 is the authoritative medical code for Leigh's disease. This classification is used in medical billing and clinical recording to specify the clinical criteria for leigh's disease (ICD-10-CM G31.82), ensuring healthcare documentation aligns with 2026 federal coding standards.
Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.
Official Registry Overview & Definition
Leigh's disease is a billable ICD-10-CM diagnosis code G31.82. Inclusion terms: Subacute necrotizing encephalopathy. Excludes2 (not included here): Reye's syndrome G93.7. Use additional code: code, if applicable, for codes G31.0-G31.83, G31.85-G31.9, to identify:; dementia with anxiety (F02.84, F02.A4, F02.B4, F02.C4); dementia with behavioral disturbance (F02.81-, F02.A1-, F02.B1-, F02.C1-); dementia with mood disturbance (F02.83, F02.A3, F02.B3, F02.C3); dementia with psychotic disturbance (F02.82, F02.A2, F02.B2, F02.C2); dementia without behavioral disturbance (F02.80, F02.A0, F02.B0, F02.C0); mild neurocognitive disorder due to known physiological condition F06.7-.
Official Tabular Instructional Notes
Sequencing, inclusion, and exclusion notes published for G31.82 in the official ICD-10-CM tabular list.
Inclusion Terms
Alternative terms the tabular list files under this code.
- Subacute necrotizing encephalopathy
Excludes2 — Not Included Here
Conditions not covered by this code, but which may be reported alongside it when both are present.
Use Additional Code
Supplementary codes the tabular list directs you to add.
- code, if applicable, for codes G31.0-G31.83, G31.85-G31.9, to identify:
- dementia with anxiety (F02.84, F02.A4, F02.B4, F02.C4)
- dementia with behavioral disturbance (F02.81-, F02.A1-, F02.B1-, F02.C1-)
- dementia with mood disturbance (F02.83, F02.A3, F02.B3, F02.C3)
- dementia with psychotic disturbance (F02.82, F02.A2, F02.B2, F02.C2)
- dementia without behavioral disturbance (F02.80, F02.A0, F02.B0, F02.C0)
- mild neurocognitive disorder due to known physiological condition F06.7-
Frequently Asked Questions (FAQ) & Clinical Guidance
Can G31.82 be reported alongside related conditions?
Per Excludes2 instructions, G31.82 and the following may both be reported when both are present: Reye's syndrome (G93.7).
Is an additional code needed with G31.82?
Use additional code(s) to specify: code, if applicable, for codes G31.0-G31.83, G31.85-G31.9, to identify:; dementia with anxiety (F02.84, F02.A4, F02.B4, F02.C4); dementia with behavioral disturbance (F02.81-, F02.A1-, F02.B1-, F02.C1-); dementia with mood disturbance (F02.83, F02.A3, F02.B3, F02.C3).
What conditions are included under G31.82?
Leigh's disease includes: Subacute necrotizing encephalopathy.
Codes in This Family (16)
Official ICD-10-CM classifications in the same code family as G31.82, with their registry titles.
- G31 — Other degenerative diseases of nervous system, not elsewhere classified
- G31.0 — Frontotemporal dementia
- G31.01 — Pick's disease
- G31.09 — Other frontotemporal neurocognitive disorder
- G31.1 — Senile degeneration of brain, not elsewhere classified
- G31.2 — Degeneration of nervous system due to alcohol
- G31.8 — Other specified degenerative diseases of nervous system
- G31.80 — Leukodystrophy, unspecified
- G31.81 — Alpers disease
- G31.83 — Neurocognitive disorder with Lewy bodies
- G31.84 — Mild cognitive impairment of uncertain or unknown etiology
- G31.85 — Corticobasal degeneration
- G31.86 — Alexander disease
- G31.87 — Primary progressive apraxia of speech
- G31.89 — Other specified degenerative diseases of nervous system
- G31.9 — Degenerative disease of nervous system, unspecified
Indexed Clinical Terms (2)
Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code.
- Encephalopathy (acute), necrotizing, subacute (Leigh)
- Leigh's disease
Related Codes & Numerical Sequence (Crawl Map)
Search engines and indexers are advised to traverse adjacent medical codes in this sub-chapter range to find correlated diagnoses or therapeutic procedures: