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G72.2 ICD-10-CM Code: Myopathy due to other toxic agents

Compare with another codeCheck this code on a claim

Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.

Coding at a Glance

Tabular directives
5 Excludes1 · 1 code-first instruction

Billable · FY2027A valid, specific ICD-10-CM code, reportable for dates of service in FY2027.

What you need to know

Source: CMS/NCHS Official ICD-10-CM tabular notes, quoted. From the CMS/NCHS tabular list for the release in force. A note the category or block publishes applies to this code too; the Instructions section marks which is which.

Code firstSequence the underlying condition before this code
Excludes1Never report with this code
  • arthrogryposis multiplex congenita (Q74.3)
  • dermatopolymyositis (M33.-)
  • ischemic infarction of muscle (M62.2-)
  • myositis (M60.-)

+1 more in Instructions

Most relevant related codes MedCoder-derived

Read off the official notes above and this code’s own position in the tabular list. Which to report is a documentation question; Compare shows the two side by side.

CompareCheck ClaimView Related Codes

Inpatient Payment Groups (MS-DRG)

Potential MS-DRG participation — not a DRG assignment.

MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v44, Appendix B.

  • MS-DRG 091 — OTHER DISORDERS OF NERVOUS SYSTEM WITH MCC (MDC 01)
  • MS-DRG 092 — OTHER DISORDERS OF NERVOUS SYSTEM WITH CC (MDC 01)
  • MS-DRG 093 — OTHER DISORDERS OF NERVOUS SYSTEM WITHOUT CC/MCC (MDC 01)

A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.

Coding instructions

Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for G72.2 in the official ICD-10-CM tabular list, quoted as published.

Source: CMS/CDC — ICD-10-CM Tabular ListRelease: FY2027Effective: October 1, 2026

Trace:FY2027 changesChange historyRelease, file and checksum

Notes without a marker are published on G72.2 itself; “inherited from” names the category or block whose note applies here.

Excludes1 — Not Coded Here

Conditions generally not reported together with this code (Excludes1) -- an error unless the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Source: inherited from G72

Code First

Underlying conditions that must be sequenced before this code.

Coder workflow for G72.2

MedCoder structured workflow — derived from this code’s own official record

Before you code G72.2

  1. G72.2’s title joins a condition with an associated condition or complication. Confirm each component is documented. Where the classification presumes the link through the “with” convention, only a provider statement that the conditions are unrelated defeats it. A combination code is assigned only when it fully identifies the documented conditions; a required second code for the stage, type or manifestation is still reported when the notes ask for it (Guidelines I.B.9, I.A.15).

    Guide: Combination codes →

  2. Check the Excludes1 note: if the documentation supports a condition named there, do not simply proceed with G72.2. Excludes1 conditions are not reported together with this code unless the record shows they are unrelated (Guidelines I.A.12.a).

    See the official tabular notes

Choose the right path

  1. Does the documentation support a condition named in G72.2’s Excludes1 note?
    Yes → Do not simply proceed: review the excluded code. Both are reported only when the record shows the two conditions are unrelated.
    No → Continue.

    ReviewQ74.3, M33, M62.2, M60, M33.2

  2. Is the underlying (etiologic) condition the Code First note names documented?
    Yes → Sequence the underlying condition first, then G72.2.
    No → Continue; do not add an underlying condition the record does not document.

Consider G72.2. Then confirm the code is valid for the date of service in the Verify section.

Documentation check

The provider’s diagnostic statement
Codes are assigned from the provider’s documented diagnosis, not from clinical criteria, test values or a medication list (Guidelines I.A.19).
The associated condition or complication
Whether the associated condition the title names is documented; the “with” convention presumes some links, and a provider statement that the conditions are unrelated defeats it (Guidelines I.A.15).
The underlying (etiologic) condition
Named in the Code First note; sequenced before this code when documented (Guidelines I.A.13).

Official instructions as workflow

  • Excludes1 — check before selecting G72.2(5 notes)

    Coding workflow: If the documentation supports a condition named in this note, do not simply proceed with G72.2: the two are not reported together. The one exception is when the record shows the two conditions are unrelated to each other.

    CompareQ74.3, M33, M62.2, M60, M33.2

    See the official tabular notes · Guidelines I.A.12.a

  • Code First — sequencing check(1 note)

    Coding workflow: Check whether the underlying or etiologic condition the note names is documented. When it is, sequence it before G72.2. Do not add an underlying condition the record does not document.

    See the official tabular notes · Guidelines I.A.13

Coding decision scenarios

Pattern scenarios for this code’s structure — decision rules, not clinical cases

Documentation: Both the condition G72.2 describes and a condition named in its Excludes1 note are documented for the same encounter.

Coding question: Can both codes be reported?

Path: Review the Excludes1 note and the excluded code, and look for a provider statement on whether the two conditions are related.

Reason: Excludes1 means the two are not coded together; the exception is when the record shows the conditions are unrelated to each other (Guidelines I.A.12.a).

ReviewQ74.3, M33, M62.2, M60, M33.2

Documentation: Only one of the components this code’s title joins is documented.

Coding question: Is G72.2 supported?

Path: Review the code for the documented component on its own.

Reason: A combination code is assigned only when it fully identifies the documented conditions; otherwise the documented component takes its own code (Guidelines I.B.9).

Documentation: The underlying condition the Code First note names is documented alongside this condition.

Coding question: How are the two sequenced?

Path: Review the Code First note.

Reason: The underlying condition is sequenced first and the manifestation follows (Guidelines I.A.13).

Every row is derived from this code’s own record — its title, tabular notes, 7th-character family and same-category siblings — with fixed MedCoder wording; nothing is inferred about a patient. The official notes and guideline text are in the sections each row links to, and they control.

Don’t confuse G72.2 with…

MedCoder analysis — pairs from this code’s official notes, distinctions written by MedCoder

The codes most likely to be picked instead of G72.2 — named in its own official notes, or sharing its laterality or encounter family — with what separates them and which documentation moves the case. Each links to the full comparison.

  • Q74.3— Excludes1 conflict (Excludes1 — generally not reported together)

    Not coded here — the tabular list excludes this pair for the same encounter.

    Not reported together with this code, except where the two conditions are documented as unrelated.

    What moves you there: Documentation of arthrogryposis multiplex congenita moves the case to Q74.3; the two are not reported together unless documented as unrelated.

    Full comparison: G72.2 vs Q74.3 →

  • M33— Excludes1 conflict (Excludes1 — generally not reported together)

    Not coded here — the tabular list excludes this pair for the same encounter.

    Not reported together with this code, except where the two conditions are documented as unrelated.

    What moves you there: Documentation of dermatopolymyositis moves the case to M33; the two are not reported together unless documented as unrelated.

    Full comparison: G72.2 vs M33 →

  • M62.2— Excludes1 conflict (Excludes1 — generally not reported together)

    Not coded here — the tabular list excludes this pair for the same encounter.

    Not reported together with this code, except where the two conditions are documented as unrelated.

    What moves you there: Documentation of ischemic infarction of muscle moves the case to M62.2; the two are not reported together unless documented as unrelated.

    Full comparison: G72.2 vs M62.2 →

  • M60— Excludes1 conflict (Excludes1 — generally not reported together)

    Not coded here — the tabular list excludes this pair for the same encounter.

    Not reported together with this code, except where the two conditions are documented as unrelated.

    What moves you there: Documentation of myositis moves the case to M60; the two are not reported together unless documented as unrelated.

    Full comparison: G72.2 vs M60 →

  • M33.2— Excludes1 conflict (Excludes1 — generally not reported together)

    Not coded here — the tabular list excludes this pair for the same encounter.

    Not reported together with this code, except where the two conditions are documented as unrelated.

    What moves you there: Documentation of polymyositis moves the case to M33.2; the two are not reported together unless documented as unrelated.

    Full comparison: G72.2 vs M33.2 →

  • G72.9— Specificity relationship (Review)

    Overlapping diagnoses in the same category.

    Overlapping codes in the same category — the documentation decides which is the more specific fit.

    What moves you there: A record that documents no more than “Myopathy, unspecified” takes G72.9; specificity in the record moves it back here.

    Full comparison: G72.2 vs G72.9 →

Relationships are read from this code's own official notes, its laterality siblings and its encounter family; the wording of each distinction is MedCoder editorial, and the documentation named in each “what moves you there” line is the official note phrase or sibling title itself. Source: CMS ICD-10-CM tabular instructional notes; ICD-10-CM Official Guidelines, Section I.A.12.a.

Coding context

Guidelines, coding notes, decision aids, relationships (with MS-DRG and CCSR classification), hierarchy, HCC, coverage and the context map: what a coder reaches for after the core. Each section names whether it is official source data, a MedCoder-derived relationship or MedCoder editorial.

Code Overview

Myopathy due to other toxic agents is a billable ICD-10-CM diagnosis code (G72.2).

MedCoder summary Summary composed by MedCoder from this code's official ICD-10-CM record. The tabular instructional notes themselves appear verbatim below.

Verify Before Coding

  • CC as a secondary diagnosis (FY2027). Can raise the stay's MS-DRG severity tier.

From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.

Relationships & Classification

MedCoder-derived relationships — computed from published CMS and AHRQ datasets

Other codes that name G72.2 or its code family, from the CMS ICD-10-CM tabular instructional notes. Tabular-note edges are stored at the code family level that carries each note.

Referenced by 5 Excludes2 notes: M60 — Myositis (via G72.-), M60-M63 — Disorders of muscles (M60-M63) (via G72.-), M61 — Calcification and ossification of muscle (via G72.-), M62 — Other disorders of muscle (via G72.-), M63 — Disorders of muscle in diseases classified elsewhere (via G72.-).

These codes’ tabular lists name this diagnosis as distinct — both may be reported when both are documented.

Referenced by 1 Code First instruction: M62.84 — Sarcopenia (via G72.-).

Each of these codes carries a Code First note naming this condition — when that code is reported, THIS code is sequenced first, ahead of it.

MS-DRG Grouper Relationships (FY2027)

Potential MS-DRG participation — not a DRG assignment.

FY2027 MS-DRG: CC — Complication or Comorbidity. Reported as a secondary diagnosis, this code raises the stay's MS-DRG severity tier — except when the principal diagnosis is one of 45 clinically related codes on its CMS exclusion list.

Named in the grouper logic of 3 MS-DRGs: DRG 091 (MDC 01), DRG 092 (MDC 01), DRG 093 (MDC 01).

From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.

Clinical classification (AHRQ CCSR):INJ030 — Drug induced or toxic related condition (default); NVS018 — Myopathies.

Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.

Related Codes

Same clinical process (MS-DRG)

Acts as CC — raises the severity of other admissions. CMS groups these diagnoses into one MS-DRG principal-diagnosis exclusion process — a CC/MCC on this list never raises severity when the principal diagnosis is also on it.

G71.13 — Myotonic chondrodystrophy, G71.14 — Drug induced myotonia, G71.19 — Other specified myotonic disorders, G71.20 — Congenital myopathy, unspecified, G71.21 — Nemaline myopathy, G71.220 — X-linked myotubular myopathy, G71.228 — Other centronuclear myopathy, G71.29 — Other congenital myopathy, G71.3 — Mitochondrial myopathy, not elsewhere classified, G71.8 — Other primary disorders of muscles, G71.9 — Primary disorder of muscle, unspecified, G72.0 — Drug-induced myopathy, G72.1 — Alcoholic myopathy, G72.3 — Periodic paralysis, G72.81 — Critical illness myopathy, G72.89 — Other specified myopathies, G72.9 — Myopathy, unspecified, G96.9 — Disorder of central nervous system, unspecified, G98.0 — Neurogenic arthritis, not elsewhere classified, G98.8 — Other disorders of nervous system, +24 more

Same clinical category (CCSR)

AHRQ's Clinical Classifications Software groups these diagnoses under the same clinical categories (Drug induced or toxic related condition, Myopathies).

G71.20 — Congenital myopathy, unspecified, G71.21 — Nemaline myopathy, G71.220 — X-linked myotubular myopathy, G71.228 — Other centronuclear myopathy, G71.29 — Other congenital myopathy, G71.3 — Mitochondrial myopathy, not elsewhere classified, G71.8 — Other primary disorders of muscles, G71.9 — Primary disorder of muscle, unspecified, G72.0 — Drug-induced myopathy, G72.1 — Alcoholic myopathy, G72.3 — Periodic paralysis, G72.41 — Inclusion body myositis [IBM], G72.49 — Other inflammatory and immune myopathies, not elsewhere classified, G72.81 — Critical illness myopathy, G72.89 — Other specified myopathies, G72.9 — Myopathy, unspecified, G73.1 — Lambert-Eaton syndrome in neoplastic disease, G73.3 — Myasthenic syndromes in other diseases classified elsewhere, G73.7 — Myopathy in diseases classified elsewhere, G92 — Toxic encephalopathy, +297 more

Same Index main term, other category

The ICD-10-CM Index to Diseases and Injuries files this code under the main term “Myopathy”; these codes share that main term but sit in a different category of the Tabular List.

E85.0 — Non-neuropathic heredofamilial amyloidosis (in, amyloidosis), E88.9 — Metabolic disorder, unspecified (in, metabolic disease NEC), G71.02 — Facioscapulohumeral muscular dystrophy (scapulohumeral), G71.035 — Limb girdle muscular dystrophy due to anoctamin-5 dysfunction (Miyoshi, type 3), G71.09 — Other specified muscular dystrophies (ocular), G71.11 — Myotonic muscular dystrophy (mytonic, proximal), G71.20 — Congenital myopathy, unspecified (congenital), G71.21 — Nemaline myopathy (rod), G71.220 — X-linked myotubular myopathy (myotubular), G71.228 — Other centronuclear myopathy (centronuclear), G71.29 — Other congenital myopathy (central core), G71.3 — Mitochondrial myopathy, not elsewhere classified (mitochondrial NEC), G71.8 — Other primary disorders of muscles (primary, specified NEC), G71.9 — Primary disorder of muscle, unspecified (primary), H05.82 — Myopathy of extraocular muscles (extraocular muscles), M30.0 — Polyarteritis nodosa (in, polyarteritis nodosa), M31.6 — Other giant cell arteritis (in, giant cell arteritis), M32.19 — Other organ or system involvement in systemic lupus erythematosus (in, systemic lupus erythematosus), M34.82 — Systemic sclerosis with myopathy (in, scleroderma), M35.03 — Sjögren syndrome with myopathy (in, sicca syndrome), +15 more

Contextual Map

Every relationship of G72.2 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Run G72.2 with these 14 related codes in Claim Check

Hierarchy

Code First (15)

Referenced by Excludes2 notes

Referenced by Code First instructions

  • M62.84 — Sarcopenia[Code First](via G72.-): “other and unspecified myopathies (G72.-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2027

Clinical classification (CCSR)

MS-DRG Grouper

MDC crossing

  • MDC 01 — Diseases and Disorders of the Nervous System[MDC crossing]: “Diseases and Disorders of the Nervous System — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs. 8,919 same-MDC procedures group here; browse them on the MDC page.”— CMS MS-DRG Definitions Manual · FY2027

Index entries

  • Myopathy, in (due to), toxic agent NEC[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2027
  • Myopathy, toxic[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2027

Nearest codes (11)

Change history

  • FY2016 — In the code set at ICD-10-CM adoption [Change history]— CMS release files (code change ledger) · icd10cm-fy2016

Reference

Index terms and tables, published questions and FAQ, every source behind this page with its release and checksum, the date-of-service check and the complete change history.

Indexed Clinical Terms (2)

Official source data — entries quoted as published, in the Index’s own lookup phrasing

Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code. These are alphabetic-index entries shown as the Index writes them — lookup phrasing, not necessarily the wording of a final diagnosis.

Sources for this page

Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.

Code, title, tabular notes and index terms Official source data
CMS/CDC ICD-10-CM FY2027 tabular list, index and tables, effective October 1, 2026 Release, file and checksum · Publisher’s page
Claim edits Official source data
CMS Definitions of Medicare Code Edits — v44.0 (October 2026) Release, file and checksum · Publisher’s page
Inpatient payment groups Official source data
CMS MS-DRG Definitions Manual (incl. Appendix B diagnosis index, Appendix C CC/MCC list, Appendix E procedure index) and IPPS Final Rule tables — v44 Release, file and checksum · Publisher’s page
Change history and date-of-service validity Official source data
CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page
Comparisons, relationships and the contextual map MedCoder-derived relationship
Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears
Summary and FAQ answers MedCoder editorial explanation
Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.

Current data releases:ICD-10-CM FY2027 · ICD-10-PCS FY2027 · HCPCS October 2026 · MS-DRG v44 · Medicare Code Editor v44.0 · NCCI PTP Q4 2026 · MUE Q4 2026 · NCD code lists 2026-01 · LCD export September 20, 2026 · All releases and sources

Labels on this page: Official source data · MedCoder-derived relationship · MedCoder editorial explanation. How to read the labels · All data sources and release dates · CMS coding rules

Cite this page

Reference this page in a research guide, syllabus or article. The release is included because code content changes each year.

MedCoder.ai. "G72.2 — Myopathy due to other toxic agents." ICD-10-CM FY2027. https://medcoder.ai/icd10/code/g72.2-myopathy-due-to-other-toxic-agents

Change history

  • FY2016 — October 1, 2015
    In the code set at ICD-10-CM adoption
    Myopathy due to other toxic agents

No changes since FY2016 — additions, deletions, description changes and billable-status changes are tracked through FY2027, and none are recorded for this code. Note changes are tracked from FY2027 only.

Nearest Codes in This Family

Official ICD-10-CM classifications closest to G72.2 in its code family, with their registry titles.

View all codes in the G72 family